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Article ; Online: Treatment of hospitalized adult patients with severe ulcerative colitis: Toronto consensus statements.

Bitton, Alain / Buie, Donald / Enns, Robert / Feagan, Brian G / Jones, Jennifer L / Marshall, John K / Whittaker, Scott / Griffiths, Anne M / Panaccione, Remo

The American journal of gastroenterology

2012 Volume 107, Issue 2, Page(s) 179–94; author reply 195

Abstract: Objectives: The objective of this study was to provide updated explicit and relevant consensus statements for clinicians to refer to when managing hospitalized adult patients with acute severe ulcerative colitis (UC).: Methods: The Canadian ... ...

Abstract	Objectives: The objective of this study was to provide updated explicit and relevant consensus statements for clinicians to refer to when managing hospitalized adult patients with acute severe ulcerative colitis (UC). Methods: The Canadian Association of Gastroenterology consensus group of 23 voting participants developed a series of recommendation statements that addressed pertinent clinical questions. An iterative voting and feedback process was used to do this in conjunction with systematic literature reviews. These statements were brought to a formal consensus meeting held in Toronto, Ontario (March 2010), when each statement was discussed, reformulated, voted upon, and subsequently revised until group consensus (at least 80% agreement) was obtained. The modified GRADE (Grading of Recommendations Assessment, Development, and Evaluation) criteria were used to rate the strength of recommendations and the quality of evidence. Results: As a result of the iterative process, consensus was reached on 21 statements addressing four themes (General considerations and nutritional issues, Steroid use and predictors of steroid failure, Cyclosporine and infliximab, and Surgical issues). Conclusions: Key recommendations for the treatment of hospitalized patients with severe UC include early escalation to second-line medical therapy with either infliximab or cyclosporine in individuals in whom parenteral steroids have failed after 72 h. These agents should be used in experienced centers where appropriate support is available. Sequential therapy with cyclosporine and infliximab is not recommended. Surgery is an option when first-line steroid therapy fails, and is indicated when second-line medical therapy fails and/or when complications arise during the hospitalization.
MeSH term(s)	Antibodies, Monoclonal/therapeutic use ; Colitis, Ulcerative/drug therapy ; Colitis, Ulcerative/surgery ; Consensus ; Cyclosporine/therapeutic use ; Hospitalization ; Humans ; Immunosuppressive Agents/therapeutic use ; Infliximab ; Treatment Outcome
Chemical Substances	Antibodies, Monoclonal ; Immunosuppressive Agents ; Cyclosporine (83HN0GTJ6D) ; Infliximab (B72HH48FLU)
Language	English
Publishing date	2012-02
Publishing country	United States
Document type	Journal Article ; Practice Guideline
ZDB-ID	390122-1
ISSN	1572-0241 ; 0002-9270
ISSN (online)	1572-0241
ISSN	0002-9270
DOI	10.1038/ajg.2011.386
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Posttreatment TNM staging is a prognostic indicator of survival and recurrence in tethered or fixed rectal carcinoma after preoperative chemotherapy and radiotherapy.

Chan, Alexander K P / Wong, Alfred / Jenken, Daryl / Heine, John / Buie, Donald / Johnson, Douglas

International journal of radiation oncology, biology, physics

2005 Volume 61, Issue 3, Page(s) 665–677

Abstract: Purpose: To evaluate the prognostic value of the posttreatment TNM stage as a predictor of outcome in locally advanced rectal cancers treated with preoperative chemotherapy and radiotherapy.: Methods and materials: Between 1993 and 2000, 128 patients ...

Abstract	Purpose: To evaluate the prognostic value of the posttreatment TNM stage as a predictor of outcome in locally advanced rectal cancers treated with preoperative chemotherapy and radiotherapy. Methods and materials: Between 1993 and 2000, 128 patients with tethered (103) or fixed (25) rectal cancers were treated with 50 Gy preoperative pelvic radiotherapy and two cycles of concurrent 5-fluorouracil infusion (20 mg/kg/d) and leucovorin (200 mg/m(2)/d) chemotherapy on Days 1-4 and 22-25 and a single bolus mitomycin C injection (8 mg/m(2)) on Day 1. Of the 128 patients, 111 had Stage T3 and 17 Stage T4 according to the rectal ultrasound or CT findings and clinical evaluation. All 128 patients underwent surgery 8 weeks after chemoradiotherapy. Postoperatively, the disease stage was determined according to the surgical and pathologic findings using the American Joint Committee on Cancer TNM staging system. Results: Of the 128 patients, 32 had postchemoradiotherapy (pCR) Stage 0 (T0N0M0), 37 pCR Stage I, 26 pCR Stage II, 28 pCR Stage III, and 5 pCR Stage IV disease. Of the 128 patients, 79 had pCR Stage T0-T2, 35 pCR Stage T3, and 14 pCR Stage T4. The rate of T stage downstaging was 66% (84 of 128). Of the 128 patients, 25% achieved a pathologic complete response, and 31 (24%) had positive nodal disease. Lymphovascular or perineural invasion was found in 13 patients (10%). The 5-year disease-specific survival rate was 97% for pCR Stage 0, 88% for pCR Stage I, 74% for pCR Stage II, 44% for pCR Stage III, and 0% for pCR Stage IV (p = 0.0000059). The 5-year relapse-free survival rate was 97% for pCR Stage 0, 80% for pCR Stage I, 72% for pCR Stage II, 42% for pCR Stage III, and 0% for pCR Stage IV (p < 0.000001). In univariate analysis, the pretreatment tumor status (fixed vs. tethered tumors), the pCR TNM stage, T stage downstaging, pathologic T4 tumors, node-positive disease after chemoradiotherapy, and lymphovascular or perineural invasion were statistically significant prognosticators of disease-specific survival and relapse-free survival. pCR Stage T4 disease was a strong predictor of local recurrence. The 5-year local control rate was 98% for pCR T0-T2, 89% for pCR T3, and 65% for pCR T4 disease (p = 0.00044). In multivariate analysis, the pCR TNM stage was the most statistically significant independent predictor of survival (p = 0.003) and relapse-free survival (p < 0.001). Conclusion: For patients who underwent preoperative chemoradiotherapy for locally advanced rectal cancer, the pCR TNM stage was a strong prognosticator of recurrence and survival. It can be used to identify high-risk patients for additional postoperative therapy.
MeSH term(s)	Adult ; Aged ; Antineoplastic Agents/therapeutic use ; Combined Modality Therapy ; Female ; Fluorouracil/therapeutic use ; Humans ; Leucovorin/therapeutic use ; Lymphatic Metastasis ; Male ; Middle Aged ; Mitomycin/therapeutic use ; Multivariate Analysis ; Neoplasm Recurrence, Local ; Neoplasm Staging/methods ; Odds Ratio ; Prognosis ; Radiotherapy Dosage ; Rectal Neoplasms/drug therapy ; Rectal Neoplasms/mortality ; Rectal Neoplasms/pathology ; Rectal Neoplasms/radiotherapy ; Recurrence ; Survival Rate
Chemical Substances	Antineoplastic Agents ; Mitomycin (50SG953SK6) ; Leucovorin (Q573I9DVLP) ; Fluorouracil (U3P01618RT)
Language	English
Publishing date	2005-03-01
Publishing country	United States
Document type	Clinical Trial ; Clinical Trial, Phase II ; Journal Article
ZDB-ID	197614-x
ISSN	1879-355X ; 0360-3016
ISSN (online)	1879-355X
ISSN	0360-3016
DOI	10.1016/j.ijrobp.2004.06.206
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Article ; Online: Decreasing colectomy rates for ulcerative colitis: a population-based time trend study.

Kaplan, Gilaad G / Seow, Cynthia H / Ghosh, Subrata / Molodecky, Natalie / Rezaie, Ali / Moran, Gordon W / Proulx, Marie-Claude / Hubbard, James / MacLean, Anthony / Buie, Donald / Panaccione, Remo

The American journal of gastroenterology

2012 Volume 107, Issue 12, Page(s) 1879–1887

Abstract: Objectives: Colectomy rates for ulcerative colitis (UC) have been inconsistently reported. We assessed temporal trends of colectomy rates for UC, stratified by emergent vs. elective colectomy indication.: Methods: From 1997 to 2009, we identified ... ...

Abstract	Objectives: Colectomy rates for ulcerative colitis (UC) have been inconsistently reported. We assessed temporal trends of colectomy rates for UC, stratified by emergent vs. elective colectomy indication. Methods: From 1997 to 2009, we identified adults hospitalized for a flare of UC. Medical charts were reviewed. Temporal changes were evaluated using linear regression models to estimate the average annual percent change (AAPC) in surgical rates. Logistic regression analysis compared: (i) UC patients responding to medical management in hospital to those who underwent colectomy; (ii) UC patients who underwent an emergent vs. elective colectomy; and (iii) temporal trends of drug utilization. Results: From 1997 to 2009, colectomy rates significantly dropped for elective colectomies with an AAPC of -7.4% (95% confidence interval (CI): -10.8%, -3.9%). The rate of emergent colectomies remained stable with an AAPC of -1.4% (95% CI: -4.8%, 2.0%). Azathioprine/6-mercaptopurine prescriptions increased from 1997 to 2009 (odds ratio (OR)=1.15; 95% CI: 1.09-1.22) and infliximab use increased after 2005 (OR=1.68; 95% CI: 1.25-2.26). A 13% per year risk adjusted reduction in the odds of colectomy (OR=0.87; 95% CI: 0.83-0.92) was observed in UC patients responding to medical management compared with those who required colectomy. Emergent colectomy patients had a shorter duration of flare (<2 weeks vs. 2-8 weeks, OR=5.31; 95% CI: 1.58-17.81) and underwent colectomy early after diagnosis (<1 year vs. 1-3 years, OR=5.48; 95% CI: 2.18-13.79). Conclusions: From 1997 to 2009, use of purine anti-metabolites increased and elective colectomy rates in UC patients decreased significantly. In contrast, emergent colectomy rates were stable, which may have been due to rapid progression of disease activity.
MeSH term(s)	Adult ; Aged ; Alberta/epidemiology ; Azathioprine/therapeutic use ; Colectomy/statistics & numerical data ; Colectomy/trends ; Colitis, Ulcerative/drug therapy ; Colitis, Ulcerative/surgery ; Drug Prescriptions/statistics & numerical data ; Elective Surgical Procedures/statistics & numerical data ; Emergency Treatment/statistics & numerical data ; Female ; Humans ; Immunosuppressive Agents/therapeutic use ; Linear Models ; Logistic Models ; Male ; Medical Records ; Mercaptopurine/therapeutic use ; Middle Aged ; Odds Ratio ; Retrospective Studies ; Time Factors
Chemical Substances	Immunosuppressive Agents ; Mercaptopurine (E7WED276I5) ; Azathioprine (MRK240IY2L)
Language	English
Publishing date	2012-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	390122-1
ISSN	1572-0241 ; 0002-9270
ISSN (online)	1572-0241
ISSN	0002-9270
DOI	10.1038/ajg.2012.333
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Article: Primary carcinoma of the rectovaginal septum diagnosed as uterine prolapse.

Nelson, Gregory S / Ghatage, Prafull / Mainprize, Thomas C / Duggan, Máire A / Buie, Donald / Nation, Jill G

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC

2003 Volume 27, Issue 11, Page(s) 1027–1030

Abstract: Background: Primary carcinoma of the rectovaginal septum is very rare. Most cases are associated with documented endometriosis, and patients will often present with vaginal or rectal bleeding.: Case: A 47-year-old woman presented to the emergency ... ...

Abstract	Background: Primary carcinoma of the rectovaginal septum is very rare. Most cases are associated with documented endometriosis, and patients will often present with vaginal or rectal bleeding. Case: A 47-year-old woman presented to the emergency department complaining of urinary symptoms and "something falling out of the vagina." She was diagnosed initially as having uterine prolapse. However, further investigations and surgery showed that she had a primary papillary serous carcinoma of the rectovaginal septum, and the carcinoma later metastasized to the lymph nodes. No evidence of endometriosis was found. Assessment and subsequent treatment of this aggressive tumour was likely delayed because of its initial benign presentation. Conclusion: Our presentation of the case of a woman with primary carcinoma of the rectovaginal septum not associated with a focus of endometriosis shows that this rare aggressive cancer may present in a clinically benign fashion.
MeSH term(s)	Carcinoma, Papillary/diagnosis ; Carcinoma, Papillary/pathology ; Carcinoma, Papillary/secondary ; Diagnosis, Differential ; Fatal Outcome ; Female ; Humans ; Lymphatic Metastasis ; Middle Aged ; Rectal Neoplasms/diagnosis ; Rectal Neoplasms/pathology ; Uterine Prolapse/diagnosis ; Uterine Prolapse/pathology ; Vaginal Neoplasms/diagnosis ; Vaginal Neoplasms/pathology
Language	English
Publishing date	2003-02-24
Publishing country	Netherlands
Document type	Case Reports ; Journal Article
ZDB-ID	2171082-X
ISSN	1701-2163
ISSN	1701-2163
DOI	10.1016/s1701-2163(16)30502-3
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Article ; Online: Postoperative complications and mortality following colectomy for ulcerative colitis.

de Silva, Shanika / Ma, Christopher / Proulx, Marie-Claude / Crespin, Marcelo / Kaplan, Belle S / Hubbard, James / Prusinkiewicz, Martin / Fong, Andrew / Panaccione, Remo / Ghosh, Subrata / Beck, Paul L / Maclean, Anthony / Buie, Donald / Kaplan, Gilaad G

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

2011 Volume 9, Issue 11, Page(s) 972–980

Abstract: Background & aims: Complications after colectomy for ulcerative colitis (UC) have not been well characterized in large, population-based studies. We characterized postoperative in-hospital complications, stratified them by severity, and assessed ... ...

Abstract	Background & aims: Complications after colectomy for ulcerative colitis (UC) have not been well characterized in large, population-based studies. We characterized postoperative in-hospital complications, stratified them by severity, and assessed independent clinical predictors, including use of immunosuppressants. Methods: We performed population-based surveillance using administrative databases to identify all adults (≥18 y) who had an International Classification of Diseases-9th/10th revisions code for UC and a colectomy from 1996 to 2009. All medical charts were reviewed. The primary outcome was severe postoperative complications, including in-hospital mortality. Logistic regression was used to assess predictors of complications after colectomy and then restricted to patients undergoing emergent or elective surgeries. Results: Of the 666 UC patients who underwent a colectomy, a postoperative complication occurred in 27.0% and the mortality rate was 1.5%. Independent predictors of postoperative complications were age (for patients >64 vs 18-34 y: odds ratio [OR], 1.95; 95% confidence interval [CI], 1.07-3.54), comorbidities (>2 vs none: OR, 1.89; 95% CI, 1.06-3.37), and admission status (emergent vs elective colectomy: OR, 1.62; 95% CI, 1.14-2.30). Significant risk factors for an emergent colectomy included time from admission to colectomy (>14 vs 3-14 d: OR, 3.32; 95% CI, 1.62-6.80) and a preoperative complication (≥1 vs 0: OR, 3.04; 95% CI, 1.33-6.91). A prescription of immunosuppressants before colectomies did not increase the risk for postoperative complications. Conclusions: Postoperative complications frequently occur after colectomy for UC, predominantly among elderly patients with multiple comorbidities. Patients who were admitted to the hospital under emergency conditions and did not respond to medical treatment had worse outcomes when surgery was performed 14 or more days after admission.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Colectomy/adverse effects ; Colitis, Ulcerative/surgery ; Female ; Humans ; Male ; Middle Aged ; Postoperative Complications/epidemiology ; Postoperative Complications/mortality ; Risk Factors ; Young Adult
Language	English
Publishing date	2011-11
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2119789-1
ISSN	1542-7714 ; 1542-3565
ISSN (online)	1542-7714
ISSN	1542-3565
DOI	10.1016/j.cgh.2011.07.016
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Article: Repeated failure of epidural analgesia: an association with epidural fat?

Lang, Scott A / Korzeniewski, Peter / Buie, Donald / Du Plessis, Stephan / Paterson, Kimiko / Morris, Gary

Regional anesthesia and pain medicine

2002 Volume 27, Issue 5, Page(s) 494–500

Abstract: Background and objectives: To report the case of a patient who experienced repeated failed epidural analgesia associated with an unusual amount of fat in the epidural space (epidural lipomatosis).: Case report: A 44-year-old female presented for an ... ...

Abstract	Background and objectives: To report the case of a patient who experienced repeated failed epidural analgesia associated with an unusual amount of fat in the epidural space (epidural lipomatosis). Case report: A 44-year-old female presented for an elective small bowel resection. An L(1-2) epidural catheter was placed for postoperative analgesia. The patient gave no indication of having pain at the time of emergence from general anesthesia or in the first 2 hours in the recovery room. Assessment of the level of hypoesthesia to ice while the patient was comfortable in the recovery room suggested a functional epidural catheter (cephalad level of T(10)). Two hours after admission to the recovery room the patient began to complain of increasing pain. Another 6 mL 0.25% bupivacaine was administered via the catheter. The patient's pain decreased, but remained substantial, and there was minimal evidence of sensory block above the T(10) level. Subsequently, a T(10) epidural catheter was placed. Testing confirmed proper placement of the catheter in the epidural space at the T(10) level. A test dose of 5 mL 0.25% bupivacaine resulted in prompt and complete relief of the patient's pain. However, the level of hypoesthesia to ice did not exceed the T(10) level. Approximately 1 hour later the patient complained of increasing discomfort again. There was no evidence of any sensory block, and there was no response to a bolus of 8 mL 1% lidocaine. A thorough examination of the patient did not suggest any cause for the pain other than a malfunctioning epidural catheter. A third epidural catheter was placed at the T(8-9) level. This catheter was again confirmed to be in the epidural space with a test dose of 10 mL 0.5% bupivacaine. The level of hypoesthesia to ice was restricted to a narrow bilateral band from T(7)-T(9). Analgesia failed 2 hours later. The epidural catheter was removed and the patient's pain was subsequently managed with intravenous patient-controlled analgesia (PCA) morphine. A magnetic resonance imaging (MRI) scan revealed extensive epidural fat dorsal to the spinal cord from C(5)-C(7) and from T(3)-T(9). An imaging diagnosis of asymptomatic epidural lipomatosis was established. Conclusion: We have described a case of repeated failure of epidural analgesia in a patient with epidural lipomatosis.
MeSH term(s)	Adipose Tissue/pathology ; Adult ; Analgesia, Patient-Controlled ; Anesthesia, Epidural ; Crohn Disease/surgery ; Epidural Space/pathology ; Female ; Humans ; Intestine, Small/surgery ; Lipomatosis/complications ; Lipomatosis/pathology ; Magnetic Resonance Imaging ; Pain, Postoperative/pathology ; Treatment Failure
Language	English
Publishing date	2002-09-25
Publishing country	England
Document type	Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1425299-5
ISSN	1532-8651 ; 1098-7339 ; 0146-521X
ISSN (online)	1532-8651
ISSN	1098-7339 ; 0146-521X
DOI	10.1053/rapm.2002.34323
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Article: Practice parameters for the management of anal fissures (revised).

Orsay, Charles / Rakinic, Jan / Perry, W Brian / Hyman, Neil / Buie, Donald / Cataldo, Peter / Newstead, Graham / Dunn, Gary / Rafferty, Janice / Ellis, C Neal / Shellito, Paul / Gregorcyk, Sharon / Ternent, Charles / Kilkenny, John / Tjandra, Joe / Ko, Clifford / Whiteford, Mark / Nelson, Richard

Diseases of the colon and rectum

2004 Volume 47, Issue 12, Page(s) 2003–2007

MeSH term(s)	Botulinum Toxins, Type A/therapeutic use ; Calcium Channel Blockers/therapeutic use ; Colorectal Surgery/adverse effects ; Colorectal Surgery/methods ; Colorectal Surgery/standards ; Evidence-Based Medicine/standards ; Fissure in Ano/etiology ; Fissure in Ano/therapy ; Humans ; Neuromuscular Agents/therapeutic use ; Nitroglycerin/therapeutic use ; Patient Selection ; Research Design/standards ; Treatment Outcome ; Vasodilator Agents/therapeutic use ; Wound Healing
Chemical Substances	Calcium Channel Blockers ; Neuromuscular Agents ; Vasodilator Agents ; Botulinum Toxins, Type A (EC 3.4.24.69) ; Nitroglycerin (G59M7S0WS3)
Language	English
Publishing date	2004-12
Publishing country	United States
Document type	Guideline ; Journal Article ; Practice Guideline
ZDB-ID	212581-x
ISSN	1530-0358 ; 0012-3706
ISSN (online)	1530-0358
ISSN	0012-3706
DOI	10.1007/s10350-004-0785-7
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Article: Practice parameters for the surveillance and follow-up of patients with colon and rectal cancer.

Diseases of the colon and rectum

2004 Volume 47, Issue 6, Page(s) 807–817

MeSH term(s)	Carcinoembryonic Antigen/blood ; Colectomy ; Colonic Neoplasms/diagnosis ; Colonic Neoplasms/surgery ; Colonoscopy ; Humans ; Neoplasm Metastasis ; Neoplasm Recurrence, Local/diagnosis ; Office Visits ; Population Surveillance/methods ; Rectal Neoplasms/diagnosis ; Rectal Neoplasms/surgery
Chemical Substances	Carcinoembryonic Antigen
Language	English
Publishing date	2004-06
Publishing country	United States
Document type	Guideline ; Journal Article ; Practice Guideline
ZDB-ID	212581-x
ISSN	1530-0358 ; 0012-3706
ISSN (online)	1530-0358
ISSN	0012-3706
DOI	10.1007/s10350-004-0519-x
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Article ; Online: 2023 Canadian Surgery Forum: Sept. 20-23, 2023.

Brière, Raphaëlle / Émond, Marce / Benhamed, Axel / Blanchard, Pierre-Gilles / Drolet, Sébastien / Habashi, Rogeh / Golbon, Bahar / Shellenberger, Jonas / Pasternak, Jesse / Merchant, Shaila / La, Julie / Sawhney, Monakshi / Brogly, Susan / Cadili, Lina / Horkoff, Michael / Ainslie, Scott / Demetrick, Jeffrey / Chai, Brian / Wiseman, Kevin /

Hwang, Hamish / Alhumoud, Zainab / Salem, Amro / Lau, Rebecca / Aw, Katherine / Nessim, Carolyn / Gawad, Nada / Alibhai, Kameela / Towaij, Chelsea / Doan, Danielle / Raîche, Isabelle / Valji, Rahim / Turner, Simon / Balmes, Patricia Nicole / Hameed, S Morad / Tan, Jun Guang Kendric / Wijesuriya, Ruwan / Hew, Nicole Lee Chui / Lund, Matthew / Hawel, Jeffrey / Gregor, Jamie / Leslie, Ken / Lenet, Tori / McIsaac, Daniel / Hallet, Julie / Jerath, Angela / Lalu, Manoj / Nicholls, Stuart / Presseau, Justin / Tinmouth, Alan / Verret, Michael / Wherrett, Christopher / Fergusson, Dean / Martel, Guillaume / Sharma, Sahil / McKechnie, Tyler / Talwar, Gaurav / Patel, Janhavi / Heimann, Luke / Doumouras, Aristithes / Hong, Dennis / Eskicioglu, Cagla / Wang, Christine / Guo, Michael / Huang, Longlong / Sun, Shaun / Davis, Noelle / Wang, Julian / Skulsky, Samuel / Sikora, Lindsey / Son, Hyo Jin / Gee, Denise / Gomez, David / Jung, James / Selvam, Rajajee / Seguin, Nieve / Zhang, Lisa / Lacaille-Ranger, Ariane / Moloo, Husein / Follett, Alicia / Holly / Organ, Michael / Pace, David / Balvardi, Saba / Kaneva, Pepa / Semsar-Kazerooni, Koorosh / Mueller, Carmen / Vassiliou, Melina / Al Mahroos, Mohammed / Fiore, Julio F / Schwartzman, Kevin / Feldman, Liane / Karimuddin, Ahmer / Liu, Gui Ping / Crump, Trafford / Sutherland, Jason / Hickey, Kala / Bonisteel, Erin M / Umali, Jurgienne / Dogar, Ibrahim / Warden, Geoffrey / Boone, Darrell / Mathieson, Alexander / Hogan, Michael / Li, Yiran / Best, Gordon / Leong, Rachel / Wiseman, Sam / Alaoui, Ahmed Amine / Hajjar, Roy / Wassef, Evelyne / Metellus, Danny Sebastien / Dagbert, François / Loungnarath, Rasmy / Ratelle, Richard / Schwenter, Frank / Debroux, Éric / Wassef, Ramses / Gagnon-Konamna, Marianne / Pomp, Alfons / Richard, Carole S / Sebajang, Herawaty / Santos, Manuela M / Shi, Ge / Leung, Regina / Lim, Christina / Knowles, Sarah / Parmar, Simran / Debru, Estifanos / Mohamed, Fardowsa / Anakin, Megan / Lee, Yung / Samarasinghe, Yasith / Khamar, Jigish / Petrisor, Bradley / Yang, Ilun / Mughal, Hanaa N / Bhugio, Mumtaz / Gok, Muhammed A / Khan, Usman A / Fernandes, Alisha R / Spence, Richard / Porter, Geoffrey / Hoogerboord, C Marius / Neumann, Katerina / Pillar, Michal / Manhas, Neraj / Melck, Adrienne / Kazi, Tania / Jessani, Ghazal / Tessier, Léa / Archer, Vicki / Park, Lily / Cohen, Dan / Parpia, Sameer / Bhandari, Mohit / Dionne, Joanna / Bolin, Sara / Afford, Rebecca / Armstrong, Madeleine / Grant, Aaron / Van Koughnett, Julie Ann / Clement, Elizabeth / Lange, Claire / Roshan, Aishwi / Scott, Tracy / Nadeau, Kara / Macmillan, Jennifer / Wilson, Jaime / Deschenes, Madeleine / Nurullah, Aruba / Cahill, Caitlin / Chen, Victoria H / Patterson, Keiko M / Wiseman, Sam M / Wen, Betty / Bhudial, Joshua / Barton, Anise / Lie, Jessica / Park, Chan Mi / Yang, Laiji / Gouskova, Natalia / Kim, Dae Hyun / Morris-Janzen, Dunavan / McLellan, Alastair / Archer, Victoria / Cloutier, Zacharie / Berg, Annie / Wiercioch, Wojtek / Labonté, Joëlle / Bisson, Pascale / Bégin, André / Cheng-Oviedo, Sonia Gabriela / Collin, Yves / Hossain, Intekhab / Ellsmere, James / El-Kefraoui, Charbel / Do, Uyen / Miller, Andrew / Kouyoumdjian, Araz / Cui, David / Khorasani, Elahe / Landry, Tara / Amar-Zifkin, Alexandre / Lee, Lawrence / Fiore, Julio / Au, Tran Michelle / Oppenheimer, Mark / Logsetty, Sarvesh / AlShammari, Raghad / AlAbri, Mohammad / Brown, Carl / Raval, Manoj J / Phang, Paul Terry / Bird, Samantha / Baig, Zarrukh / Abu-Omar, Nawaf / Gill, Dilip / Suresh, Soumiya / Ginther, Nathan / Karpinski, Marta / Ghuman, Amandeep / Malik, Peter R A / Zabolotniuk, Taryn / Mashal, Sarah / Boulanger, Nathalie / Watt, Larry / Razek, Tarek / Fata, Paola / Grushka, Jeremy / Wong, Evan G / Landry, Maxim / Mackey, Sarah / Fairbridge, Nicholas / Greene, Alison / Borgoankar, Mark / Kim, Cullen / DeCarvalho, Diana / Wigen, Robin / Walser, Emily / Davidson, Jacob / Dorward, Michael / Muszynski, Leanne / Dann, Celia / Seemann, Natashia / Lam, Jennifer / Harding, Kaitlyn / Lowik, A J / Guinard, Caroline / Ma, Odelle / Mocanu, Valentin / Lin, Andrea / Karmali, Shahzeer / Bigam, David / Greaves, Grant / Parker, Brent / Nguyen, Vu / Ahmed, Azim / Yee, Belinda / Perren, Joël / Norman, Mathew / Grey, Morgan / Perini, Rafael / Jowhari, Fahd / Bak, Adrian / Drung, Jeremy / Allen, Laura / Wiseman, Daniele / Moffat, Bradley / Lee, Jeremy K H / McGuire, Catherine / Tudorache, Mihaela / Park, Lily J / Borges, Flavia K / Nenshi, Rahima / Jacka, Michael / Heels-Ansdell, Diane / Simunovic, Marko / Bogach, Jessica / Serrano, Pablo E / Thabane, Lehana / Devereaux, P J / Farooq, Sauleha / Lester, Erica / Kung, Janice / Bradley, Nori / Ahn, San / Prince, Nicole / Cheng-Boivin, Olivia / Wang, Harry / Quartermain, Liam / Tan, Sherry / Shamess, Jennifer / Simard, Mathilde / Vigil, Humberto / Hanna, Mary / Azam, Riordan / Ko, Gary / Zhu, Mayanne / Raveendran, Yanuga / Lam, Christine / Tang, Janet / Bajwa, Amrit / Englesakis, Marina / Reel, Emma / Cleland, Jordan / Snell, Laura / Lorello, Gianni / Cil, Tulin / Ahn, Hilalion San / Dube, Catherine / Smith, David / Leclerc, Alexie / Rostom, Alaa / Calo, Natalia / Thavorn, Kednapa / Laplante, Simon / Liu, Louis / Khan, Nadia / Okrainec, Allan / Bruyninx, Gladys / Georgescu, Ilinca / Khokhotva, Vladislav / Yang, Shuling / Spoyalo, Karina / Rebello, Thais Ayres / Chhipi-Shrestha, Gyan / Mayson, Kelly / Sadiq, Rehan / Hewage, Kasun / MacNeill, Andrea / Muncner, Susan / Li, Mo Yu / Mihajlovic, Igor / Dykstra, Mark / Snelgrove, Ryan / Wang, Haili / Schweitzer, Christina / Garcha, Ivneet / Jogiat, Uzair / Baracos, Vickie / Turner, Simon R / Eurich, Dean / Filafilo, Heather / Rouhi, Armin / Bédard, Alexandre / Bédard, Eric L R / Patel, Yogita S / Alaichi, Jacob A / Agzarian, John / Hanna, Wael C / Provost, Esther / Shayegan, Bobby / Adili, Anthony / Mistry, Nikkita / Gatti, Anthony A / Farrokhyar, Forough / Xie, Feng / Sullivan, Kerrie A / Liberman, Moishe / Gonzalez, Anne V / Nayak, Rahul / Yasufuku, Kazuhiro / Cross, Sam / Haché, Pier-Luc / Galvaing, Geraud / Simard, Serge / Grégoire, Jocelyn / Bussières, Jean / Lacasse, Yves / Sassi, Sami / Champagne, Catherine / Laliberté, Anne-Sophie / Jeong, Jin Yong / Wilson, Hillary / Blakely, Pam / Dang, Jerry / Sun, Warren / Wong, Clarence / Hakim, Suhail Yaqoob / Azizi, Samim / El-Menyar, Ayman / Rizoli, Sandro / Al-Thani, Hassan / French, Daniel / Li, Chao / Gossen, Shiloh / Bailey, Jon / Tibbo, Phil / Crocker, Candice / Bondzi-Simpson, Adom / Ribeiro, Tiago / Kidane, Biniam / Ko, Michael / Coburn, Natalie / Kulkarni, Girish / Ramzee, Ahmed Faidh / Afifi, Ibrahim / Alani, Mushrek / Chughtai, Talat / Huo, Bright / Manos, Daria / Xu, Zhaolin / Kontouli, Katerina-Maria / Chun, Samuel / Fris, John / Wallace, Allison M R / French, Daniel G / Giffin, Catherine / Dayan, Gabriel / Farivar, Alexander / Weessies, Cara / Robinson, Madeline / Bednarek, Leeann / Buduhan, Gordon / Liu, Richard / Tan, Lawrence / Srinathan, Sadeesh K / Nasralla, Awrad / Safieddine, Najib / Gazala, Sayf / Simone, Carmine / Ahmadi, Negar / Hilzenrat, Roy / Blitz, Maurice / Deen, Shaun / Humer, Michael / Jugnauth, Anand / Kerr, Laura / Sun, Simon / Browne, Ikennah / Patel, Yogita / Hanna, Wael / Loshusan, Brandon / Shamsil, Arefin / Naish, Michael D / Qiabi, Mehdi / Patel, Rajni / Malthaner, Richard / Pooja, Patel / Roberto, Ribeiro / Greg, Hirsch / Daniel, French / Huynh, Caroline / Sharma, Sohat / Vieira, Arthur / Jain, Fagun / Lee, Yejun / Mousa-Doust, Dorsa / Costa, Jonice / Mezei, Michelle / Chapman, Kristine / Briemberg, Hannah / Jack, Kristin / Grant, Kyle / Choi, James / Yee, John / McGuire, Anna L / Abdul, Sami Aftab / Khazoom, Francois / Gilbert, Sebastien / Sundaresan, Sudhir / Jones, Daniel / Seely, Andrew J E / Villeneuve, Patrick J / Maziak, Donna E / Pigeon, Claudie-Anne / Frigault, Jonathan / Roy, Ève-Marie / Bujold-Pitre, Kristopher / Courval, Valérie / Tessier, Lea / Gangam, Nirupa / Lee, Jay / Patel, Ashaka / Ichhpuniani, Simarpreet / Elder, Geoffrey / Chen, Andrew / Logie, Kathleen / Benko, Randy / Castelo, Matthew / Paszat, Lawrence / Hansen, Bettina / Scheer, Adena / Faught, Neil / Nguyen, Lena / Baxter, Nancy / Wu, Kathy / Passos, Edward / Sachdeva, Anjali / Fei, Linda Y N / Caycedo, Antonio / Patel, Sunil / Popa, Teodora / Boudreau, Lee / Grin, Andrea / Wang, Tao / Phang, Terry / Raval, Manoj / Candy, Sydney / Nanda, Kareena / Li, Christine / Kroeker, Karen / Roy, Haven / Helewa, Ramzi M / Johnson, Garrett / Singh, Harminder / Hyun, Eric / Moffatt, Dana / Vergis, Ashley / Balmes, Patricia / Liu, Jerry / Webber, Sandra / Shariff, Farhana / Hochman, Dave / Park, Jason / Robitaille, Stephan / Wang, Anna / Maalouf, Michael / Alali, Naser / Elhaj, Hiba / Liberman, Sender / Charlebois, Patrick / Stein, Barry / Hu, Richard / Williams, Lara / Musselman, Reilly / Lemke, Maddy / Samarasinghe, Nadeesha / Vogt, Kelly / Brackstone, Muriel / Zwiep, Terry / Alam, Armaghan / Ghuman, Anu / James, Nicholas / Laczko, Dora / Lee, Stephanie / Sritharan, Praveen / Hershorn, Olivia / Phang, P Terry / Chen, Alex / Boutros, Marylise / Caminsky, Natasha / Dumitra, Teodora / Faris-Sabboobeh, Sarah / Demian, Marie / Rigas, Georgia / Monton, Olivia / Smith, Allister / Moon, Jeongyoon / Garfinkle, Richard / Vasilevsky, Carol-Ann / Rajabiyazdi, Fateme / Courage, Emily / LeBlanc, Danielle / Benesch, Matthew / Hartwig, Katia / Armstrong, Casey / Engelbrecht, Reniel / Fagan, Mitchell / Borgaonkar, Mark / Shanahan, Jessica / Salama, Ebram / Arsenault, Mylène / Leon, Nathalie / Loiselle, Carmen / Rajabiyazdi, Fatemeh / Brennan, Kelly / Rai, Mandip / Farooq, Ameer / McClintock, Chad / Kong, Weidong / Boukhili, Neyla / Paradis, Tiffany / Liberman, A Sender / Feldman, Liane S / Abner, Deborah / Alam, Tarik / Beyer, Elaine / Evans, Michele / Hill, Mary / Johnston, Debra / Lohnes, Karla / Menard, Svea / Pitcher, Nicole / Sair, Kelly / Smith, Bev / Yarjau, Bonita / LeBlanc, 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Alibrahim, Huseen / Giundi, Christian / Munir, Haroon / Safar, Ali / Sabboobeh, Sarah / Holland, Jessica / Abtahi, Sean / Chhor, Allison / Caminsky, Natasha Grace / Moon, Jenny Jeongyoon / Marinescu, Daniel / Pang, Allison / Al-Abri, Mohammed / Gee, Elliott / Morena, Nina / Ben-Zvi, Libby / Hayman, Victoria / Hou, Mary / Nguyen, Diana / Rentschler, Carrie A / Meguerditchian, Ari N / Mir, Zuhaib / Fei, Linda / McKeown, Sandra / Dinchong, Rachelle / Cofie, Nicholas / Dalgarno, Nancy / Cheifetz, Rona / Jaffer, Alisha / Cullinane, Carolyn / Feeney, Gerard / Jalali, Amirhossein / Merrigan, Anne / Baban, Chwanrow / Buckley, Juliette / Tormey, Shona / Wu, Rongrong / Takabe, Kazuaki / O'Brien, Shalana / Kazazian, Karineh / Abdalaty, Ali Hosni / Brezden, Christine / Burkes, Ron / Chen, Eric / Govindarajan, Anand / Jang, Raymond / Lukovic, Jelena / Mesci, Aruz / Quereshy, Fayez / Swallow, Carol / Marini, Wanda / Zheng, Weiyue / Murakami, Kiichi / Ohashi, Pamela / Reedijk, Michael / Ivankovic, 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Jeff / Bayley, Conrad / Watanabe, Akie / Yao, Susan / Prisman, Eitan / Groot, Gary / Mitmaker, Elliot / Walker, Ross / Wu, Jonn / Lai, Chi Kien / Eskander, Antoine / Wasserman, Jonathan / Mercier, Frederic / Roth, Kathryn / Gill, Sabrina / Villamil, Carlos / Goldstein, David / Munro, Vicki / Pathak, Alok / Lee, Debon / Nguyen, Anne / Rajendran, Luckshi / Claasen, Marco / Ivanics, Tommy / Selzner, Nazia / McGilvray, Ian / Cattral, Mark / Ghanekar, Anand / Moulton, Carol-Anne / Reichman, Trevor / Shwaartz, Chaya / Metser, Ur / Winter, Erin / Gallinger, Steven / Sapisochin, Gonzalo / Glinka, Juan / Waugh, Evelyn / Skaro, Anton / Tang, Epharaim / Charbonneau, Janyssa / Brind'Amour, Alexandre / Turgeon, Alexis F / O'Connor, Sarah / Couture, Thomas / Wang, Yifan / Yoshino, Osamu / Driedger, Michael / Beckman, Michael / Vrochides, Dionisios / Martinie, John / Alabduljabbar, Abdulrahman / Aali, Maral / Lightfoot, Christopher / Gala-Lopez, Boris / Labelle, Maud / D'Aragon, Frédérick / Hirpara, 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Shingoose, Geraldine / Molnar, Amber / Nguyen, Francis / Schneider, Romano / Fecso, Andras B / Sharma, Priya / Maeda, Azusa / Jackson, Timothy / McLean, Cheynne / MacVicar, Sarah / McLennan, Steffane / Purich, Kieran / Birch, Daniel W / Switzer, Noah J / Jeffery, Lisa / Ryley, Alexis / Schellenberg, Morgan / Owattanapanich, Natthida / Emigh, Brent / Nichols, Chance / Dilday, Joshua / Ugarte, Chaiss / Onogawa, Atsushi / Matsushima, Kazuhide / Martin, Matthew J / Inaba, Kenji / Shapiro, Doug / Im, Daniel / Lam, Lydia / Rezende-Neto, Joao / Lemke, Madeline / Leeper, William / Walser, Eric / Bateni, Sarah / Barabash, Victoria / Barr, Austin / Chan, Wing / Warraich, Ahmed / Gillman, Lawrence / Ziesmann, Markus / Momic, Jovana / Yassin, Nouf / Kim, Mella / Makish, Amy / Smith, Shane / Ball, Ian / Moffat, Brad / Parry, Neil / Kroeker, Jenna / Evans, David / Fansia, Nahal / Notik, Chana / Coyle, Guire / Seben, David / Smith, Jaiden / Tanenbaum, Brandy / Freedman, Corey / Nathens, Avery / 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Canadian journal of surgery. Journal canadien de chirurgie

2023 Volume 66, Issue 6 Suppl 1, Page(s) S54–S136

Language	English
Publishing date	2023-12-13
Publishing country	Canada
Document type	Journal Article
ZDB-ID	410651-9
ISSN	1488-2310 ; 0008-428X
ISSN (online)	1488-2310
ISSN	0008-428X
DOI	10.1503/cjs.014223
Database	MEDical Literature Analysis and Retrieval System OnLINE

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