Article ; Online: COV-BT Ire study: safety and efficacy of the BNT162b2 mRNA COVID-19 vaccine in patients with brain tumors.
2022 Volume 43, Issue 6, Page(s) 3519–3522
Abstract: Background: The BNT162b2 vaccine conferred 95% protection against COVID-19 in people aged 16 years or older.: Objective: The aim of this observational study was to evaluate safety and efficacy of vaccine in patients affected by primary brain tumor ( ... ...
| Abstract | Background: The BNT162b2 vaccine conferred 95% protection against COVID-19 in people aged 16 years or older. Objective: The aim of this observational study was to evaluate safety and efficacy of vaccine in patients affected by primary brain tumor (PBT). Methods: We proposed COVID-19 vaccine to all patients affected by PBT followed by Neuroncology Unit of National Cancer Institute Regina Elena. Results: 102 patients received the first dose, 100 the second, and 73 patients received the booster dose. After first dose, we observed one patient with fever and severe fatigue, while after the second one, we recorded adverse events in ten patients. No correlation was observed between adverse events and comorbidities. Conclusions: The COVID-19 vaccine is safe and well tolerated in PBT patients. |
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| MeSH term(s) | BNT162 Vaccine ; Brain Neoplasms/complications ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Humans ; RNA, Messenger ; SARS-CoV-2 | |||||
| Chemical Substances | COVID-19 Vaccines ; RNA, Messenger ; BNT162 Vaccine (N38TVC63NU) | |||||
| Language | English | |||||
| Publishing date | 2022-04-09 | |||||
| Publishing country | Italy | |||||
| Document type | Journal Article ; Observational Study | |||||
| ZDB-ID | 2016546-8 | |||||
| ISSN | 1590-3478 ; 1590-1874 | |||||
| ISSN (online) | 1590-3478 | |||||
| ISSN | 1590-1874 | |||||
| DOI | 10.1007/s10072-022-06054-3 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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