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Article: Depth of Invasion: Influence of the Latest TNM Classification on the Prognosis of Clinical Early Stages of Oral Tongue Squamous Cell Carcinoma and Its Association with Other Histological Risk Factors.

Navarro Cuéllar, Ignacio / Espías Alonso, Samuel / Alijo Serrano, Francisco / Herrera Herrera, Isabel / Zamorano León, José Javier / Del Castillo Pardo de Vera, José Luis / López López, Ana María / Maza Muela, Cristina / Arenas de Frutos, Gema / Ochandiano Caicoya, Santiago / Tousidonis Rial, Manuel / García Sevilla, Alba / Antúnez-Conde, Raúl / Cebrián Carretero, José Luis / García-Hidalgo Alonso, María Isabel / Salmerón Escobar, José Ignacio / Burgueño García, Miguel / Navarro Vila, Carlos / Navarro Cuéllar, Carlos

Cancers

2023 Volume 15, Issue 19

Abstract: Background: The American Joint Committee on Cancer (AJCC), in its 8th edition, introduces modifications to the previous TNM classification, incorporating tumour depth of invasion (DOI). The aim of this research is to analyse the prognosis (in terms of ... ...

Abstract	Background: The American Joint Committee on Cancer (AJCC), in its 8th edition, introduces modifications to the previous TNM classification, incorporating tumour depth of invasion (DOI). The aim of this research is to analyse the prognosis (in terms of disease-free survival and overall survival) of clinical early stage (I and II) squamous cell carcinomas of the oral tongue according to the DOI levels established by the AJCC in its latest TNM classification to assess changes to the T category and global staging system and to evaluate the association between DOI and other histological risk factors. Methods: A retrospective longitudinal observational study of a series of cases was designed. All patients were treated with upfront surgery at our institution between 2010 and 2019. The variables of interest were defined and classified into four groups: demographic, clinical, histological and evolutive control. Univariate and multivariate analyses were carried out and survival functions were calculated using the Kaplan-Meier method. Statistical significance was established for Results: Sixty-one patients were included. The average follow-up time was 47.42 months. Fifteen patients presented a loco-regional relapse (24.59%) and five developed distant disease (8.19%). Twelve patients died (19.67%). Statistically significant differences were observed, with respect to disease-free survival ( Conclusions: Depth of invasion is a histological risk factor in early clinical stages of oral tongue squamous cell carcinoma. Depth of invasion impacts negatively on patient prognosis, is capable per se of modifying the T category and the global tumour staging, and is associated with the presence of cervical metastatic disease, perineural invasion and tumoural differentiation grade.
Language	English
Publishing date	2023-10-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers15194882
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Clinical, radiological and therapeutic features of keratocystic odontogenic tumours: a study over a decade.

Sánchez-Burgos, Rocío / González-Martín-Moro, Javier / Pérez-Fernández, Elia / Burgueño-García, Miguel

Journal of clinical and experimental dentistry

2014 Volume 6, Issue 3, Page(s) e259–64

Abstract: Factors associated with the potential for recurrence of keratocystic odontogenic tumours (KCOT) still remain to be clearly determined and no consensus exists concerning the management of KCOT. The purpose of this study was to evaluate different clinical ... ...

Abstract	Factors associated with the potential for recurrence of keratocystic odontogenic tumours (KCOT) still remain to be clearly determined and no consensus exists concerning the management of KCOT. The purpose of this study was to evaluate different clinical factors associated with KCOT and its treatment methods. A retrospective review was performed of 55 cases treated from 2001 to 2010. Of the 55 cases, 27% were associated with an impacted or semi-impacted tooth. The majority of the lesions (82%) were located in tooth-bearing areas, and the overall mandibular to maxilla ratio of tumour occurrence was 5:1. The treatment options included enucleation, marsupialisation, or peripheral ostectomy, with or without the use of Carnoy´s solution. Recurrence was found in 14 cases (25%). No significant association was seen between recurrence and age, symptomatic cases, location of the lesion, or unilocular or multilocular appearance. The recurrence rate was higher in the group with tooth involvement, more marked in cases with third molar involvement. Statistical analysis showed a significant relation between recurrence and the type of treatment, with higher rates in cases treated with enucleation associated with tooth extraction. In our series, those cases with a closer relation with dental tissues showed a higher risk of recurrence, suggesting the need for a distinct classification for peripheral variants of KCOT. Key words:Keratocystic odontogenic tumour, Odontogenic keratocyst, Odontogenic cysts, Keratocyst, Carnoy's solution.
Language	English
Publishing date	2014-07-01
Publishing country	Spain
Document type	Journal Article
ZDB-ID	2586647-3
ISSN	1989-5488
ISSN	1989-5488
DOI	10.4317/jced.51408
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Versatility of nasolabial flaps in oral cavity reconstructions.

Alonso-Rodríguez, Estefanía / Cebrián-Carretero, José-Luis / Morán-Soto, María-José / Burgueño-García, Miguel

Medicina oral, patologia oral y cirugia bucal

2014 Volume 19, Issue 5, Page(s) e525–30

Abstract: Objectives: Describe the techniques involved and the results obtained witn nasolabial flaps in small and medium-sized defects of the oral cavity. The procedure is an easy resconstructive option with a high success rate and with very good aesthetic and ... ...

Abstract	Objectives: Describe the techniques involved and the results obtained witn nasolabial flaps in small and medium-sized defects of the oral cavity. The procedure is an easy resconstructive option with a high success rate and with very good aesthetic and functional outcomes. Study design: A retrospective analysis of 16 nasolabial flap reconstructions in 15 oncological patients with oral cavity defects undergoing single-stage surgical interventions. We evaluate the tumor type, its location, size, the resective and reconstructive techniques involved, as well as any complications. Results: Out of 15 patients, 9 were male and 6 female, with ages ranging from 60-85 years. The primary tumor was located in the mandibular or maxillary gingiva in 7 patients, the lateral margin of the tongue in 5, the floor of the mouth in 3 and the mandibular symphysis in a single patient. The tumors were of a small to medium size. All patients underwent intraoral resections. In most cases, a cervical dissection was performed. All flaps were completed as single-stage surgical interventions, with 14 unilateral and 2 bilateral procedures. Five patients had received radiotherapy treatment for previous tumors. During the follow up period, which ranged from 4 months to 8 years, only one patient required their flap to be thinned, there were two incidents of surgical wound dehiscence, two hematomas and one orocutaneous fistula, none of which affected the survival of the flap. Conclusions: The nasolabial flap proves highly versatile in oral cavity reconstructions, coupled with a minimal morbidity of the donor region and good aesthetic and functional results. Its high vascularity allows for cervical dissections to be carried out or even for radiotherapy to be administered prior to it. It is straightforward, safe, and carrying it out as a single-stage intervention makes it the ideal surgical option for small to medium intraoral defects in edentulous patients with other comorbidities.
MeSH term(s)	Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell/surgery ; Female ; Humans ; Lip/transplantation ; Male ; Middle Aged ; Mouth/surgery ; Mouth Neoplasms/surgery ; Nose/transplantation ; Reconstructive Surgical Procedures/methods ; Retrospective Studies ; Surgical Flaps
Language	English
Publishing date	2014-09-01
Publishing country	Spain
Document type	Evaluation Study ; Journal Article
ZDB-ID	2171573-7
ISSN	1698-6946 ; 1698-4447
ISSN (online)	1698-6946
ISSN	1698-4447
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Article: Osteochondroma of coronoid process: a rare etiology of jacob disease.

Losa-Muñoz, Pedro Manuel / Burgueño-García, Miguel / González-Martín-Moro, Javier / Sánchez-Burgos, Rocio

Craniomaxillofacial trauma & reconstruction

2014 Volume 7, Issue 4, Page(s) 306–309

Abstract: Jacob disease is a rare entity consisting of the formation of a pseudojoint between the inner surface of the zygoma and the coronoid process. This requires constant contact between the two implicated surfaces. It can be achieved by two mechanisms: one by ...

Abstract	Jacob disease is a rare entity consisting of the formation of a pseudojoint between the inner surface of the zygoma and the coronoid process. This requires constant contact between the two implicated surfaces. It can be achieved by two mechanisms: one by an enlarged coronoid process and two by an anterior displacement of the coronoid process caused by a temporomandibular joint (TMJ) disorder. Although von Langenbeck described coronoid process hyperplasia in 1853, Oscar Jacob was the first author to describe the pathology in 1899. Since then, only a few cases have been published in the literature. The authors report a rare case of Jacob disease caused by an osteochondroma of the coronoid process, which is even less common, and review the literature.
Language	English
Publishing date	2014-06-13
Publishing country	United States
Document type	Case Reports
ISSN	1943-3875
ISSN	1943-3875
DOI	10.1055/s-0034-1378182
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Traqueotomías en pacientes críticos durante la pandemia por COVID-19. Estudio preliminar de nuestra experiencia en el Hospital Universitario La Paz de Madrid

del Castillo Pardo de Vera, José Luis / Cebrián Carretero, José Luis / Guiñales Díaz de Cevallos, Jorge / Garrido Ortega, Pedro / Noguera Tomás, Jorge / Manuel Muñoz Caro, Jesús / González Otero, Teresa / Morán Soto, María José / Malet Contreras, Albert / Sánchez Gallego-Albertos, Celia / Figueira Iglesias, Juan Carlos / Asensio Martín, María José / Añón Elizalde, José Manuel / Burgueño García, Miguel

Revista Española de Cirugía Oral y Maxilofacial v.42 n.2 2020

2020

Abstract: RESUMEN El brote epidémico causado por el virus SARS-CoV-2 se encuentra plenamente activo en España. Alrededor del 10-15 % de los pacientes ingresados precisan cuidados en unidades de críticos, siendo intubados de forma prolongada y precisando la ... ...

Abstract	RESUMEN El brote epidémico causado por el virus SARS-CoV-2 se encuentra plenamente activo en España. Alrededor del 10-15 % de los pacientes ingresados precisan cuidados en unidades de críticos, siendo intubados de forma prolongada y precisando la realización de traqueotomías. Se realiza un estudio observacional de las traqueotomías realizadas por nuestro Servicio de Cirugía Oral y Maxilofacial a pacientes COVID-19 de unidades de cuidados intensivos realizadas entre el 17 de marzo y el 17 de abril de 2020. El estudio analiza aspectos epidemiológicos y clínicos de los pacientes, el tipo de técnica quirúrgica empleada, el tiempo quirúrgico, el tipo de cánula empleada, las complicaciones postquirúrgicas y el seguimiento clínico de los pacientes. Un total de 22 pacientes fueron sometidos a traquetomía reglada abierta. Fueron dieciocho hombres y cuatro mujeres de edades entre 40 y 77 años (64,9 años de media). En todos los casos la realización de traqueotomía fue como consecuencia del proceso pulmonar por la neumonia bilateral COVID-19. Dos pacientes presentaron un neumotórax en el postoperatorio inmediato como complicación, un paciente falleció durante la realización del procedimiento y otro tras su llegada a la Unidad de Cuidados Intensivos tras la realización de la traqueotomía. A pesar de que la traqueotomía es una técnica quirúrgica reglada, las características especiales de los pacientes COVID-19 hacen de este procedimiento una situación crítica por la inestabilidad pulmonar y la rápida desaturación del paciente. Todo ello obliga a la realización del procedimiento por facultativos con experiencia para disminuir el tiempo quirúrgico y poder enfrentarse a cualquier eventualidad.
Keywords	COVID-19 ; traqueotomía ; equipo de protección ; riesgo de infección ; covid19
Language	Spanish
Publishing date	2020-06-01
Publisher	Sociedad Española de Cirugía Oral y Maxilofacial y de Cabeza y Cuello
Publishing country	es
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Predictable dental rehabilitation in maxillomandibular reconstruction with free flaps. The role of implant guided surgery.

Cebrian-Carretero, José-Luis / Guiñales-Díaz de Cevallos, Jorge / Sobrino, José-Andrés / Yu, Tomás / Burgueño-García, Miguel

Medicina oral, patologia oral y cirugia bucal

2014 Volume 19, Issue 6, Page(s) e605–11

Abstract: The reconstruction of maxillomandibular defects secondary to oral cancer surgery, represent a great challenge for Maxillofacial surgeons. During the last decades the reconstructive surgery has experimented a big advance due to the development of the ... ...

Abstract	The reconstruction of maxillomandibular defects secondary to oral cancer surgery, represent a great challenge for Maxillofacial surgeons. During the last decades the reconstructive surgery has experimented a big advance due to the development of the microsurgical techniques. At present, we are able to reconstruct complex defects using free flaps that provide both soft and bone tissue. Fibula, iliac crest and scapula free flaps have been the three classic options for the maxillomandibular reconstruction owing to the amount of bone that this flaps provide, allowing the posterior dental rehabilitation with implants. Today, our objective it is not only the aesthetic reconstruction, but also the functional reconstruction of the patients enhancing their life quality. Guided implant surgery in free flap reconstructed patients has become an essential tool, helping to define the exact position of the dental implant in the flap. In this way it is possible to look for the areas with better bone conditions, avoiding the osteosynthesis material used to fixate the flap with the native bone and deciding the best biomechanical option, in terms of number and situation of the implants, for the future dental prostheses. In summary, using the guided implant surgery, it is possible to design an exact and predictable dental implant rehabilitation in patients with oral cancer who are reconstructed with free microvascular flap, resulting in an optimal aesthetic and functional result.
MeSH term(s)	Dental Implants ; Free Tissue Flaps ; Humans ; Jaw Neoplasms/surgery ; Male ; Mandible/surgery ; Maxilla/surgery ; Middle Aged ; Reconstructive Surgical Procedures/methods
Chemical Substances	Dental Implants
Language	English
Publishing date	2014-11-01
Publishing country	Spain
Document type	Case Reports ; Journal Article
ZDB-ID	2171573-7
ISSN	1698-6946 ; 1698-4447
ISSN (online)	1698-6946
ISSN	1698-4447
DOI	10.4317/medoral.19116
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Osteochondroma of Coronoid Process: A Rare Etiology of Jacob Disease

Losa-Muñoz, Pedro Manuel / Burgueño-García, Miguel / González-Martín-Moro, Javier / Sánchez-Burgos, Rocio

Craniomaxillofacial Trauma & Reconstruction

2014 Volume 07, Issue 04, Page(s) 306–309

Abstract	Jacob disease is a rare entity consisting of the formation of a pseudojoint between the inner surface of the zygoma and the coronoid process. This requires constant contact between the two implicated surfaces. It can be achieved by two mechanisms: one by an enlarged coronoid process and two by an anterior displacement of the coronoid process caused by a temporomandibular joint (TMJ) disorder. Although von Langenbeck described coronoid process hyperplasia in 1853, Oscar Jacob was the first author to describe the pathology in 1899. Since then, only a few cases have been published in the literature. The authors report a rare case of Jacob disease caused by an osteochondroma of the coronoid process, which is even less common, and review the literature.
Keywords	osteochondroma of coronoid ; Jacob disease ; coronoidectomy
Language	English
Publishing date	2014-06-13
Publisher	Thieme Medical Publishers
Publishing place	Stuttgart ; New York
Document type	Article
ISSN	1943-3883 ; 1943-3875
ISSN (online)	1943-3883
ISSN	1943-3875
DOI	10.1055/s-0034-1378182
Database	Thieme publisher's database

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Article: Transfusion Requirements in Microsurgical Reconstruction in Maxillofacial Surgery: Ethical and Legal Problems of Patients Who Are Jehovah's Witnesses.

Martin, Lorena Pingarron / Arias-Gallo, Javier / Perez-Chrzanowska, Hanna / Seco, Pilar Ruiz / Moro, Javier Gonzalez M / Burgueño-Garcia, Miguel

Craniomaxillofacial trauma & reconstruction

2013 Volume 6, Issue 1, Page(s) 31–36

Abstract: Objective To study transfusion requirements in patients with cancer undergoing head and neck reconstructive surgery and to discuss surgical and anesthetic strategies to reduce blood loss when the patient is a Jehovah's Witness. Material and Methods A ... ...

Abstract	Objective To study transfusion requirements in patients with cancer undergoing head and neck reconstructive surgery and to discuss surgical and anesthetic strategies to reduce blood loss when the patient is a Jehovah's Witness. Material and Methods A descriptive study to expose the percentage of blood transfusions performed in patients with cancer undergoing microsurgical reconstructions in the department of oral and maxillofacial surgery of the referred hospital in the past 9 years. Results Two hundred thirty-seven microsurgical reconstructions were performed in head and neck tumors between January 2001 and December 2009. Statistical analysis shows a significant decrease (p = 0.035) in the number of patients needing transfusions patients in recent years. Conclusions The treatment of patients who are Jehovah's Witnesses is an ethical and moral dilemma for the clinician and in particular for surgeons.
Language	English
Publishing date	2013-01-24
Publishing country	United States
Document type	Journal Article
ISSN	1943-3875
ISSN	1943-3875
DOI	10.1055/s-0033-1333828
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Bronchial impaction of an implant screwdriver after accidental aspiration: report of a case and revision of the literature.

Pingarrón Martín, Lorena / Morán Soto, María José / Sánchez Burgos, Rocío / Burgueño García, Miguel

Oral and maxillofacial surgery

2009 Volume 14, Issue 1, Page(s) 43–47

Abstract: Background: Adverse outcomes resulting from aspiration or ingestion of instruments and materials can occur in any dental procedure. Clinical manifestation depends on the location, the obstructive potential of the foreign body, and the temporal factor ... ...

Abstract	Background: Adverse outcomes resulting from aspiration or ingestion of instruments and materials can occur in any dental procedure. Clinical manifestation depends on the location, the obstructive potential of the foreign body, and the temporal factor since the accidental incident. Accidental inhalation of dental appliances can be an even more serious event than ingestion and must always be treated as an emergency situation. Case report: A 62-year-old woman was admitted to our hospital with the suspicion of ingestion of a screwdriver implants. In spite of the clinically asymptomatic presentation, chest radiography in posteroanterior and lateral projections showed a radiopaque dental instrument impacted on the right main inferior bronchus. Rigid bronchoscope was successful to remove the dental instrument under general anesthesia, and the patient was discharged 24 h later. Conclusion: Aspiration and ingestion of dental foreign objects are infrequent, but they can occur at large multidisciplinary dental procedures. These episodes have the potential to result in acute medical and life-threatening emergencies since the beginning of the event or at a late stage in proceeding in the underdiagnosed patient. Prevention of such incidents is, therefore, the best approach via the mandatory use of precautions during all dental procedures, and in case of suspicion with no retrievable material, patient must always be submitted to a radiographic study.
MeSH term(s)	Accidents ; Bronchi ; Bronchoscopy ; Dental Implantation, Endosseous/instrumentation ; Dental Instruments ; Emergencies ; Female ; Foreign Bodies/diagnostic imaging ; Foreign Bodies/therapy ; Humans ; Middle Aged ; Radiography ; Respiratory Aspiration
Language	English
Publishing date	2009-10-16
Publishing country	Germany
Document type	Case Reports ; Journal Article
ZDB-ID	2406731-3
ISSN	1865-1569 ; 1865-1550
ISSN (online)	1865-1569
ISSN	1865-1550
DOI	10.1007/s10006-009-0178-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Tracheotomies in critical patients during the COVID-19 pandemia. Preliminary study of our experiences at La Paz University Hospital of Madrid Traqueotomías en pacientes críticos durante la pandemia por COVID-19. Estudio preliminar de nuestra experiencia e

del Castillo Pardo de Vera, José Luis Cebrián Carretero José Luis Guiñales Díaz de Cevallos Jorge / Garrido Ortega, Pedro / Noguera Tomás, Jorge / Manuel Muñoz Caro, Jesús González Otero Teresa / Morán Soto, María José Malet Contreras Albert / Sánchez Gallego-Albertos, Celia / Figueira Iglesias, Juan Carlos / Asensio Martín, María José Añón Elizalde José Manuel Burgueño García Miguel

Revista Española de Cirugía Oral y Maxilofacial

Abstract: ABSTRACT The outbreak caused by the SARS-CoV-2 virus is currently very active in Spain Many infected people still require to be hospitalized Around 10-15 % of hospitalized patients require intensive care, where they are intubated for a prolonged period, ... ...

Abstract	ABSTRACT The outbreak caused by the SARS-CoV-2 virus is currently very active in Spain Many infected people still require to be hospitalized Around 10-15 % of hospitalized patients require intensive care, where they are intubated for a prolonged period, needing tracheotomies some weeks after the intubation We will be conducting an observational study of the tracheotomies performed by our oral and maxillofacial Department to COVID-19 patients on intensive care units between March 17th and April 17th, 2020 This study will be analyzing the patients' epidemiological and clinical aspects, surgical technique employed, surgical time, type of cannula used, postoperative complications and the patients' clinical monitoring A total of 22 patients underwent open elective tracheotomy There were twenty-two males and three females aged between 40 and 77 (mean: 64,9 years-old) In all cases tracheotomy was carried out due to pulmonary process caused by COVID-19 bilateral pneumonia Two patients presented pneumothorax in the immediate postoperatory care as a complication, one perished during the procedure and another did so after arriving to the Intensive Care Unit after the tracheotomy surgery Even though tracheotomy is a ruled surgical technique, the special characteristics of COVID-19 patients make of this procedure a critical situation, mainly due to lung instability and quick desaturation of the patients This requires the surgery to be carried out by experienced physicians in order to reduce operative time and to be able to react to any eventualities that may arise
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #635795
Database	COVID19

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