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  1. Article: Idiopathic Spontaneous Pneumoperitoneum and Call for a Multi-Institutional Database.

    Awe, Adam M / Burke, Lauren M B / Long, Millie / Natarajan, Brahma / Overby, David W / Campbell, Shannelle

    ACG case reports journal

    2023  Volume 10, Issue 11, Page(s) e01208

    Abstract: Idiopathic spontaneous pneumoperitoneum (ISP) refers to intraperitoneal air of unknown origin when other more common etiologies such as traumatic, intrathoracic, and gynecologic etiologies have been excluded. We present a case of a 42-year-old woman with ...

    Abstract Idiopathic spontaneous pneumoperitoneum (ISP) refers to intraperitoneal air of unknown origin when other more common etiologies such as traumatic, intrathoracic, and gynecologic etiologies have been excluded. We present a case of a 42-year-old woman with insignificant history presenting with ISP who underwent exploratory laparoscopy and thorough diagnostic workup that was ultimately unrevealing. This case report adds to the existing literature of ISP, and the authors recommend initiating a multi-institutional database to improve our understanding of ISP and contribute to developing consensus guidelines for presumed ISP.
    Language English
    Publishing date 2023-11-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000001208
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Type II Endoleak Nidus Volume on Arterial and Delayed Phases of Initial CT Angiography after Endovascular Abdominal Aortic Aneurysm Repair Predicts Persistent Endoleak and Aneurysm Sac Enlargement.

    Yu, Hyeon / Ellis, Joshua S / Burke, Lauren M B / Isaacson, Ari J / Burke, Charles T

    Radiology. Cardiothoracic imaging

    2021  Volume 3, Issue 1, Page(s) e200527

    Abstract: Purpose: To evaluate type II endoleak nidus volume (ENV) in the arterial phase (ENV: Materials and methods: Ninety-three patients (mean age ± standard deviation, 72 years ± 8; range, 56-88 years) with EVAR and type II endoleak were included in a ... ...

    Abstract Purpose: To evaluate type II endoleak nidus volume (ENV) in the arterial phase (ENV
    Materials and methods: Ninety-three patients (mean age ± standard deviation, 72 years ± 8; range, 56-88 years) with EVAR and type II endoleak were included in a single-institution retrospective study conducted between March 1, 2005, and December 31, 2018. ENV
    Results: The accuracy of ENV
    Conclusion: ENV
    Language English
    Publishing date 2021-02-04
    Publishing country United States
    Document type Journal Article
    ISSN 2638-6135
    ISSN (online) 2638-6135
    DOI 10.1148/ryct.2021200527
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Association of Contrast-Enhanced Ultrasound-Derived Kidney Cortical Microvascular Perfusion with Kidney Function.

    Srivastava, Anand / Sridharan, Anush / Walmer, Rachel W / Kasoji, Sandeep K / Burke, Lauren M B / Dayton, Paul A / Johnson, Kennita A / Chang, Emily H

    Kidney360

    2022  Volume 3, Issue 4, Page(s) 647–656

    Abstract: Background: Individuals with chronic kidney disease (CKD) have decreased kidney cortical microvascular perfusion, which may lead to worsening kidney function over time, but methods to quantify kidney cortical microvascular perfusion are not feasible to ... ...

    Abstract Background: Individuals with chronic kidney disease (CKD) have decreased kidney cortical microvascular perfusion, which may lead to worsening kidney function over time, but methods to quantify kidney cortical microvascular perfusion are not feasible to incorporate into clinical practice. Contrast-enhanced ultrasound (CEUS) may quantify kidney cortical microvascular perfusion, which requires further investigation in individuals across the spectrum of kidney function.
    Methods: We performed CEUS on a native kidney of 83 individuals across the spectrum of kidney function and calculated quantitative CEUS-derived kidney cortical microvascular perfusion biomarkers. Participants had a continuous infusion of the microbubble contrast agent (Definity) with a flash-replenishment sequence during their CEUS scan. Lower values of the microbubble velocity (
    Results: Thirty-eight individuals with CKD (mean age±SD 65.2±12.6 years, median [IQR] eGFR 31.5 [18.9-41.5] ml/min per 1.73 m
    Conclusions: CEUS-derived kidney cortical microvascular perfusion biomarkers are associated with eGFR. Future studies are needed to determine if CEUS-derived kidney cortical microvascular perfusion biomarkers have prognostic value.
    MeSH term(s) Adult ; Aged ; Biomarkers ; Humans ; Kidney/diagnostic imaging ; Middle Aged ; Perfusion ; Renal Insufficiency, Chronic/diagnostic imaging ; Ultrasonography/methods
    Chemical Substances Biomarkers
    Language English
    Publishing date 2022-01-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ISSN 2641-7650
    ISSN (online) 2641-7650
    DOI 10.34067/KID.0005452021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Therapies for hepatocellular carcinoma: overview, clinical indications, and comparative outcome evaluation-part one: curative intention.

    Yacoub, Joseph H / Hsu, Christine C / Fishbein, Thomas M / Mauro, David / Moon, Andrew / He, Aiwu R / Bashir, Mustafa R / Burke, Lauren M B

    Abdominal radiology (New York)

    2021  Volume 46, Issue 8, Page(s) 3528–3539

    Abstract: Hepatocellular carcinoma (HCC) offers unique management challenges as it commonly occurs in the setting of underlying chronic liver disease. The management of HCC is directed primarily by the clinical stage. The most commonly used staging system is the ... ...

    Abstract Hepatocellular carcinoma (HCC) offers unique management challenges as it commonly occurs in the setting of underlying chronic liver disease. The management of HCC is directed primarily by the clinical stage. The most commonly used staging system is the Barcelona-Clinic Liver Cancer system, which considers tumor burden based on imaging, liver function and the patient's performance status. Early-stage HCC can be managed with therapies of curative intent including surgical resection, liver transplantation, and ablative therapies. This manuscript reviews the various treatment options for HCC with a curative intent, such as locablative therapy types, surgical resection, and transplant. Indications, contraindications and outcomes of the various treatment options are reviewed. Multiple concepts relating to liver transplant are discussed including Milan criteria, OPTN policy, MELD exception points, downstaging to transplant and bridging to transplant.
    MeSH term(s) Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/therapy ; Humans ; Intention ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/pathology ; Liver Neoplasms/therapy ; Liver Transplantation ; Neoplasm Staging ; Treatment Outcome
    Language English
    Publishing date 2021-04-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2839786-1
    ISSN 2366-0058 ; 2366-004X
    ISSN (online) 2366-0058
    ISSN 2366-004X
    DOI 10.1007/s00261-021-03069-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Therapies for hepatocellular carcinoma: overview, clinical indications, and comparative outcome evaluation. Part two: noncurative intention.

    Yacoub, Joseph H / Mauro, David / Moon, Andrew / He, Aiwu R / Bashir, Mustafa R / Hsu, Christine C / Fishbein, Thomas M / Burke, Lauren M B

    Abdominal radiology (New York)

    2021  Volume 46, Issue 8, Page(s) 3540–3548

    Abstract: Locoregional therapies can be offered to hepatocellular carcinoma patients as a bridge to transplant, to downstage disease burden for transplant eligibility, or for disease control to prolong survival. Systemic therapies also play a large role in HCC ... ...

    Abstract Locoregional therapies can be offered to hepatocellular carcinoma patients as a bridge to transplant, to downstage disease burden for transplant eligibility, or for disease control to prolong survival. Systemic therapies also play a large role in HCC treatment, occasionally in conjunction with other methods. This manuscript reviews the various treatment options for HCC with a historically noncurative intent.
    MeSH term(s) Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/therapy ; Humans ; Intention ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/therapy
    Language English
    Publishing date 2021-04-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2839786-1
    ISSN 2366-0058 ; 2366-004X
    ISSN (online) 2366-0058
    ISSN 2366-004X
    DOI 10.1007/s00261-021-03074-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Radiology Dictation Errors with COVID-19 Protective Equipment: Does Wearing a Surgical Mask Increase the Dictation Error Rate?

    Femi-Abodunde, Abiola / Olinger, Kristen / Burke, Lauren M B / Benefield, Thad / Lee, Ellie R / McGinty, Katrina / Mervak, Benjamin M

    Journal of digital imaging

    2021  Volume 34, Issue 5, Page(s) 1294–1301

    Abstract: Our aim was to determine the effect of wearing a surgical mask on the number and type of dictation errors in unedited radiology reports. IRB review was waived for this prospective matched-pairs study in which no patient data was used. Model radiology ... ...

    Abstract Our aim was to determine the effect of wearing a surgical mask on the number and type of dictation errors in unedited radiology reports. IRB review was waived for this prospective matched-pairs study in which no patient data was used. Model radiology reports (n = 40) simulated those typical for an academic medical center. Six randomized radiologists dictated using speech-recognition software with and without a surgical mask. Dictations were compared to model reports and errors were classified according to type and severity. A statistical model was used to demonstrate that error rates for all types of errors were greater when masks are worn compared to when they are not (unmasked: 21.7 ± 4.9 errors per 1000 words, masked: 27.1 ± 2.2 errors per 1000 words; adjusted p < 0.0001). A sensitivity analysis was performed, excluding a reader with a large number of errors. The sensitivity analysis found a similar difference in error rates for all types of errors, although significance was attenuated (unmasked: 16.9 ± 1.9 errors per 1000 words, masked: 20.1 ± 2.2 errors per 1000 words; adjusted p = 0.054). We conclude that wearing a mask results in a near-significant increase in the rate of dictation errors in unedited radiology reports created with speech-recognition, although this difference may be accentuated in some groups of radiologists. Additionally, we find that most errors are minor single incorrect words and are unlikely to result in a medically relevant misunderstanding.
    MeSH term(s) COVID-19 ; Humans ; Masks ; Prospective Studies ; Radiology ; Radiology Information Systems ; SARS-CoV-2
    Language English
    Publishing date 2021-09-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1033897-4
    ISSN 1618-727X ; 0897-1889
    ISSN (online) 1618-727X
    ISSN 0897-1889
    DOI 10.1007/s10278-021-00502-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Ultrasound-guided Intralesional Injection of Talimogene laherparepvec (Imlygic) for Advanced Melanoma: Technical Note on a Preliminary Experience.

    Burke, Lauren M B / Yu, Hyeon / Burke, Kaleigh / Gwynn, Morgan / Louie, Raphael J / Ollila, David W / Rn, Paula Landman / Collichio, Frances

    Cardiovascular and interventional radiology

    2021  Volume 44, Issue 5, Page(s) 801–806

    Abstract: Purpose: To evaluate the safety and feasibility of ultrasound-guided intralesional injection of Talimogene laherparepvec (Imlygic, T-VEC) in patients with advanced non-palpable melanoma.: Materials and methods: Fourteen consecutive patients (mean age, ...

    Abstract Purpose: To evaluate the safety and feasibility of ultrasound-guided intralesional injection of Talimogene laherparepvec (Imlygic, T-VEC) in patients with advanced non-palpable melanoma.
    Materials and methods: Fourteen consecutive patients (mean age, 67.9 years ± 13.0; range, 40-88; 12 males) with unresectable, locally advanced melanoma underwent ultrasound-guided intralesional injections of T-VEC (July 2016-March 2020) into subcutaneous lesions. Tumor response to the injection was evaluated at the last follow-up. Technical success and complication rates were recorded.
    Results: The T-VEC injection was technically successful in all patients with all lesions successfully punctured (100%). The mean number of lesions, injection cycles, and injection volumes were 4.1 ± 2.6 (1-9), 6.5 ± 3.0 (3-12), and 2.6 mL ± 1.4 (1-4 mL), respectively. During the follow-up period (mean, 21.0 months ± 13.4; range 1-43.6 months), complete remission, partial remission, persistent disease, and disease progression were observed in 6 (42.9%), 3 (21.4%), 1 (7.1%), and 4 (28.6%) patients, respectively. Post-treatment symptoms observed in 9 patients (64.3%), including fever (n = 2), fatigue (n = 1), headache (n = 1), pain (n = 1), mouth sores (n = 1), and flu-like symptoms (n = 3). No injection-related complications occurred in all procedures.
    Conclusion: Intralesional injection of T-VEC for non-palpable metastases under ultrasound guidance is safe and feasible in patients with advanced melanoma.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents, Immunological/administration & dosage ; Biological Products/administration & dosage ; Disease Progression ; Female ; Herpesvirus 1, Human ; Humans ; Injections, Intralesional/methods ; Male ; Melanoma/diagnosis ; Melanoma/drug therapy ; Middle Aged ; Neoplasm Staging ; Oncolytic Virotherapy/adverse effects ; Oncolytic Virotherapy/methods ; Skin Neoplasms/diagnosis ; Skin Neoplasms/surgery ; Therapy, Computer-Assisted/methods ; Ultrasonography, Interventional/methods
    Chemical Substances Antineoplastic Agents, Immunological ; Biological Products ; talimogene laherparepvec
    Language English
    Publishing date 2021-01-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603082-8
    ISSN 1432-086X ; 0342-7196 ; 0174-1551
    ISSN (online) 1432-086X
    ISSN 0342-7196 ; 0174-1551
    DOI 10.1007/s00270-020-02748-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Utility of Pelvic Computed Tomography Angiography Prior to Prostatic Artery Embolization.

    Isaacson, Ari J / Burke, Lauren M B

    Seminars in interventional radiology

    2016  Volume 33, Issue 3, Page(s) 224–230

    Abstract: Pelvic computed tomography angiography (CTA) prior to prostatic artery embolization is a beneficial tool for preprocedural planning to increase the likelihood of success during what can be a challenging procedure. Additionally, the same CTA images can be ...

    Abstract Pelvic computed tomography angiography (CTA) prior to prostatic artery embolization is a beneficial tool for preprocedural planning to increase the likelihood of success during what can be a challenging procedure. Additionally, the same CTA images can be used for calculating the baseline prostate volume as well as for intraprocedural anatomic guidance, adding to the value of the scan. This article discusses the technique used for pelvic CTA and its role in preprocedural assessment of the pelvic vasculature prior to prostatic artery embolization.
    Language English
    Publishing date 2016-03-21
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 848341-3
    ISSN 1098-8963 ; 0739-9529
    ISSN (online) 1098-8963
    ISSN 0739-9529
    DOI 10.1055/s-0036-1586150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Chronic Pancreatitis or Pancreatic Tumor? A Problem-solving Approach.

    Wolske, Kristy Marie / Ponnatapura, Janardhana / Kolokythas, Orpheus / Burke, Lauren M B / Tappouni, Rafel / Lalwani, Neeraj

    Radiographics : a review publication of the Radiological Society of North America, Inc

    2019  Volume 39, Issue 7, Page(s) 1965–1982

    Abstract: Certain inflammatory pancreatic abnormalities may mimic pancreatic ductal adenocarcinoma at imaging, which precludes accurate preoperative diagnosis and may lead to unnecessary surgery. Inflammatory conditions that may appear masslike include mass- ... ...

    Abstract Certain inflammatory pancreatic abnormalities may mimic pancreatic ductal adenocarcinoma at imaging, which precludes accurate preoperative diagnosis and may lead to unnecessary surgery. Inflammatory conditions that may appear masslike include mass-forming chronic pancreatitis, focal autoimmune pancreatitis, and paraduodenal pancreatitis or "groove pancreatitis." In addition, obstructive chronic pancreatitis can mimic an obstructing ampullary mass or main duct intraductal papillary mucinous neoplasm. Secondary imaging features such as the duct-penetrating sign, biliary or main pancreatic duct skip strictures, a capsulelike rim, the pancreatic duct-to-parenchyma ratio, displaced calcifications in patients with chronic calcific pancreatitis, the "double duct" sign, and vessel encasement or displacement can help to suggest the possibility of an inflammatory mass or a neoplastic process. An awareness of the secondary signs that favor a diagnosis of malignant or inflammatory lesions in the pancreas can help the radiologist to perform the differential diagnosis and determine the degree of suspicion for malignancy. Repeat biopsy or surgical resection may be necessary to achieve an accurate diagnosis and prevent unnecessary surgery for inflammatory conditions.
    MeSH term(s) Autoimmune Pancreatitis/blood ; Autoimmune Pancreatitis/diagnostic imaging ; Biomarkers, Tumor/blood ; CA-19-9 Antigen/blood ; Calcinosis/diagnostic imaging ; Carcinoma, Pancreatic Ductal/blood ; Carcinoma, Pancreatic Ductal/diagnostic imaging ; Diagnosis, Differential ; Humans ; Magnetic Resonance Imaging/methods ; Multidetector Computed Tomography/methods ; Pancreatic Ducts/diagnostic imaging ; Pancreatic Neoplasms/blood ; Pancreatic Neoplasms/diagnostic imaging ; Pancreatitis, Chronic/blood ; Pancreatitis, Chronic/diagnostic imaging ; Ultrasonography/methods
    Chemical Substances Biomarkers, Tumor ; CA-19-9 Antigen
    Language English
    Publishing date 2019-10-04
    Publishing country United States
    Document type Journal Article ; Review ; Webcast
    ZDB-ID 603172-9
    ISSN 1527-1323 ; 0271-5333
    ISSN (online) 1527-1323
    ISSN 0271-5333
    DOI 10.1148/rg.2019190011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Updates on LI-RADS Treatment Response Criteria for Hepatocellular Carcinoma: Focusing on MRI.

    Patel, Richa / Aslam, Anum / Parikh, Neehar D / Mervak, Benjamin / Mubarak, Eman / Higgins, Lily / Lala, Kayli / Conner, Jack F / Khaykin, Valerie / Bashir, Mustafa / Do, Richard Kinh Gian / Burke, Lauren M B / Smith, Elainea N / Kim, Charles Y / Shampain, Kimberly L / Owen, Dawn / Mendiratta-Lala, Mishal

    Journal of magnetic resonance imaging : JMRI

    2023  Volume 57, Issue 6, Page(s) 1641–1654

    Abstract: As the incidence of hepatocellular carcinoma (HCC) and subsequent treatments with liver-directed therapies rise, the complexity of assessing lesion response has also increased. The Liver Imaging Reporting and Data Systems (LI-RADS) treatment response ... ...

    Abstract As the incidence of hepatocellular carcinoma (HCC) and subsequent treatments with liver-directed therapies rise, the complexity of assessing lesion response has also increased. The Liver Imaging Reporting and Data Systems (LI-RADS) treatment response algorithm (LI-RADS TRA) was created to standardize the assessment of response after locoregional therapy (LRT) on contrast-enhanced CT or MRI. Originally created based on expert opinion, these guidelines are currently undergoing revision based on emerging evidence. While many studies support the use of LR-TRA for evaluation of HCC response after thermal ablation and intra-arterial embolic therapy, data suggest a need for refinements to improve assessment after radiation therapy. In this manuscript, we review expected MR imaging findings after different forms of LRT, clarify how to apply the current LI-RADS TRA by type of LRT, explore emerging literature on LI-RADS TRA, and highlight future updates to the algorithm. EVIDENCE LEVEL: 3. TECHNICAL EFFICACY: Stage 2.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/radiotherapy ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/radiotherapy ; Data Systems ; Magnetic Resonance Imaging/methods ; Retrospective Studies ; Contrast Media ; Sensitivity and Specificity
    Chemical Substances Contrast Media
    Language English
    Publishing date 2023-03-05
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 1146614-5
    ISSN 1522-2586 ; 1053-1807
    ISSN (online) 1522-2586
    ISSN 1053-1807
    DOI 10.1002/jmri.28659
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