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  1. Article ; Online: Pathology in Practice.

    Aronson, Riley K / Conway, David S / Pumphrey, Stephanie A / Almela, Ramón M / Powers, Adam / Burnum, Annabelle / Conrado, Francisco O

    Journal of the American Veterinary Medical Association

    2022  Volume 261, Issue 1, Page(s) 1–4

    MeSH term(s) Animals ; Animal Diseases/diagnosis
    Language English
    Publishing date 2022-08-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.22.06.0269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Canine spinal cord glioma.

    Rissi, Daniel R / Barber, Renee / Burnum, Annabelle / Miller, Andrew D

    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

    2016  Volume 29, Issue 1, Page(s) 126–132

    Abstract: Spinal cord glioma is uncommonly reported in dogs. We describe the clinicopathologic and diagnostic features of 7 cases of canine spinal cord glioma and briefly review the veterinary literature on this topic. The median age at presentation was 7.2 y. Six ...

    Abstract Spinal cord glioma is uncommonly reported in dogs. We describe the clinicopathologic and diagnostic features of 7 cases of canine spinal cord glioma and briefly review the veterinary literature on this topic. The median age at presentation was 7.2 y. Six females and 1 male were affected and 4 dogs were brachycephalic. The clinical course lasted from 3 d to 12 wk, and clinical signs were progressive and associated with multiple suspected neuroanatomic locations in the spinal cord. Magnetic resonance imaging of 6 cases revealed T2-weighted hyperintense lesions with variable contrast enhancement in the spinal cord. All dogs had a presumptive clinical diagnosis of intraparenchymal neoplasia or myelitis based on history, advanced imaging, and cerebrospinal fluid analysis. Euthanasia was elected in all cases because of poor outcome despite anti-inflammatory or immunosuppressive treatment or because of poor prognosis at the time of diagnosis. Tumor location during autopsy ranged from C1 to L6, with no clear predilection for a specific spinal cord segment. The diagnosis was based on histopathology and the immunohistochemistry expression of glial fibrillary acidic protein, oligodendrocyte lineage transcription factor 2, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, neuron-specific enolase, synaptophysin, and Ki-67. Diagnoses consisted of 4 cases of oligodendroglioma, 2 cases of gliomatosis cerebri, and 1 astrocytoma. This case series further defines the clinicopathologic features of canine spinal glioma and highlights the need for comprehensive immunohistochemistry in addition to routine histopathology to confirm the diagnosis of these tumors.
    MeSH term(s) Animals ; Diagnosis, Differential ; Dog Diseases/diagnosis ; Dog Diseases/diagnostic imaging ; Dog Diseases/pathology ; Dogs ; Female ; Glioma/diagnosis ; Glioma/veterinary ; Immunohistochemistry/veterinary ; Magnetic Resonance Imaging/veterinary ; Male ; Spinal Cord Neoplasms/diagnosis ; Spinal Cord Neoplasms/veterinary
    Language English
    Publishing date 2016-12-20
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 287603-6
    ISSN 1943-4936 ; 1040-6387
    ISSN (online) 1943-4936
    ISSN 1040-6387
    DOI 10.1177/1040638716673127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Canine spinal cord glioma

    Rissi, Daniel R. / Barber, Renee / Burnum, Annabelle / Miller, Andrew D.

    Journal of Veterinary Diagnostic Investigation. 2017 Jan., v. 29, no. 1 p.126-132

    a case series and review of the literature

    2017  

    Abstract: Spinal cord glioma is uncommonly reported in dogs. We describe the clinicopathologic and diagnostic features of 7 cases of canine spinal cord glioma and briefly review the veterinary literature on this topic. The median age at presentation was 7.2 y. Six ...

    Abstract Spinal cord glioma is uncommonly reported in dogs. We describe the clinicopathologic and diagnostic features of 7 cases of canine spinal cord glioma and briefly review the veterinary literature on this topic. The median age at presentation was 7.2 y. Six females and 1 male were affected and 4 dogs were brachycephalic. The clinical course lasted from 3 d to 12 wk, and clinical signs were progressive and associated with multiple suspected neuroanatomic locations in the spinal cord. Magnetic resonance imaging of 6 cases revealed T2-weighted hyperintense lesions with variable contrast enhancement in the spinal cord. All dogs had a presumptive clinical diagnosis of intraparenchymal neoplasia or myelitis based on history, advanced imaging, and cerebrospinal fluid analysis. Euthanasia was elected in all cases because of poor outcome despite anti-inflammatory or immunosuppressive treatment or because of poor prognosis at the time of diagnosis. Tumor location during autopsy ranged from C1 to L6, with no clear predilection for a specific spinal cord segment. The diagnosis was based on histopathology and the immunohistochemistry expression of glial fibrillary acidic protein, oligodendrocyte lineage transcription factor 2, 2′,3′-cyclic-nucleotide 3′-phosphodiesterase, neuron-specific enolase, synaptophysin, and Ki-67. Diagnoses consisted of 4 cases of oligodendroglioma, 2 cases of gliomatosis cerebri, and 1 astrocytoma. This case series further defines the clinicopathologic features of canine spinal glioma and highlights the need for comprehensive immunohistochemistry in addition to routine histopathology to confirm the diagnosis of these tumors.
    Keywords astrocytoma ; cerebrospinal fluid ; disease course ; dogs ; euthanasia ; histopathology ; immunohistochemistry ; immunosuppression ; magnetism ; males ; necropsy ; oligodendroglia ; phosphopyruvate hydratase ; prognosis ; spinal cord ; transcription factors ; Central nervous system tumors ; spinal cord glioma ; spinal cord neoplasia
    Language English
    Dates of publication 2017-01
    Size p. 126-132.
    Publishing place SAGE Publications
    Document type Article ; Online
    ZDB-ID 287603-6
    ISSN 1943-4936 ; 1040-6387
    ISSN (online) 1943-4936
    ISSN 1040-6387
    DOI 10.1177/1040638716673127
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: What is your diagnosis? Digit aspirate from a dog.

    Camus, Melinda S / Burnum, Annabelle / Howerth, Elizabeth W / Brouwer, Christopher J / Sharma, Ajay / Huang, Chien-Tsun

    Veterinary clinical pathology

    2017  Volume 46, Issue 4, Page(s) 635–636

    MeSH term(s) Animals ; Biopsy, Needle/veterinary ; Bone Neoplasms/diagnosis ; Bone Neoplasms/pathology ; Bone Neoplasms/veterinary ; Chondrosarcoma/diagnosis ; Chondrosarcoma/pathology ; Chondrosarcoma/veterinary ; Dog Diseases/diagnosis ; Dogs ; Female ; Foot/diagnostic imaging ; Foot Diseases/diagnosis ; Foot Diseases/pathology ; Foot Diseases/veterinary
    Language English
    Publishing date 2017-06-12
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2114702-4
    ISSN 1939-165X ; 0275-6382
    ISSN (online) 1939-165X
    ISSN 0275-6382
    DOI 10.1111/vcp.12518
    Database MEDical Literature Analysis and Retrieval System OnLINE

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