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Book: Neuroimagem

Busatto Filho, Geraldo

(Revista brasileira de psiquiatria ; 23, Supl. 1)

2001

Author's details	ed.: Geraldo Busatto Filho
Series title	Revista brasileira de psiquiatria ; 23, Supl. 1
Collection
Language	Portuguese
Size	SI64, VIII S. : Ill., graph. Darst.
Publishing place	São Paulo
Publishing country	Brazil
Document type	Book
HBZ-ID	HT013185680
Database	Catalogue ZB MED Medicine, Health

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Article ; Online: Psychiatric neuroimaging research in Brazil: historical overview, current challenges, and future opportunities.

Busatto Filho, Geraldo / Rosa, Pedro G / Serpa, Mauricio H / Squarzoni, Paula / Duran, Fabio L

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)

2021 Volume 43, Issue 1, Page(s) 83–101

Abstract: The last four decades have witnessed tremendous growth in research studies applying neuroimaging methods to evaluate pathophysiological and treatment aspects of psychiatric disorders around the world. This article provides a brief history of psychiatric ... ...

Abstract	The last four decades have witnessed tremendous growth in research studies applying neuroimaging methods to evaluate pathophysiological and treatment aspects of psychiatric disorders around the world. This article provides a brief history of psychiatric neuroimaging research in Brazil, including quantitative information about the growth of this field in the country over the past 20 years. Also described are the various methodologies used, the wealth of scientific questions investigated, and the strength of international collaborations established. Finally, examples of the many methodological advances that have emerged in the field of in vivo neuroimaging are provided, with discussion of the challenges faced by psychiatric research groups in Brazil, a country of limited resources, to continue incorporating such innovations to generate novel scientific data of local and global relevance.
MeSH term(s)	Brazil ; Humans ; Mental Disorders/diagnostic imaging ; Neuroimaging
Language	English
Publishing date	2021-02-01
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2024119-7
ISSN	1809-452X ; 1809-452X
ISSN (online)	1809-452X
ISSN	1809-452X
DOI	10.1590/1516-4446-2019-0757
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The impact of a TV report in schizophrenia stigma reduction: A quasi-experimental study.

Bosoni, Nathaly de Oliveira / Busatto Filho, Geraldo / de Barros, Daniel Martins

The International journal of social psychiatry

2017 Volume 63, Issue 3, Page(s) 275–277

Abstract: Background: Stigma is a major problem in schizophrenia, and the most effective way to reduce it is to provide information. But literature lacks studies evaluating long-term efficacy of mass communication.: Aims: This is a pilot study to assess if a ... ...

Abstract	Background: Stigma is a major problem in schizophrenia, and the most effective way to reduce it is to provide information. But literature lacks studies evaluating long-term efficacy of mass communication. Aims: This is a pilot study to assess if a brief intervention (TV report) may have long-term effects. Method: Assessing stigma scores from subjects before and after seeing a vignette. Results: We found that the social distance and restriction to patients not only fell after a brief intervention but also kept lower after 1 and 3 months. Conclusion: We conclude that even brief intervention may create persistent impact in reducing discrimination.
Language	English
Publishing date	2017-05
Publishing country	England
Document type	Journal Article
ZDB-ID	3062-4
ISSN	1741-2854 ; 0020-7640
ISSN (online)	1741-2854
ISSN	0020-7640
DOI	10.1177/0020764016688713
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Article ; Online: From where we came: Absence of internal migration effect on psychosis in two case-control Brazilian samples.

Shuhama, Rosana / Carmo, Lorena de Souza Rodrigues do / Busatto Filho, Geraldo / Santos, Jair Lício Ferreira / Del-Ben, Cristina Marta / Scazufca, Marcia / Menezes, Paulo Rossi

Schizophrenia research

2019 Volume 212, Page(s) 241–242

MeSH term(s)	Adolescent ; Adult ; Brazil/epidemiology ; Case-Control Studies ; Female ; Humans ; Male ; Middle Aged ; Population Dynamics/statistics & numerical data ; Psychotic Disorders/epidemiology ; Young Adult
Language	English
Publishing date	2019-08-08
Publishing country	Netherlands
Document type	Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	639422-x
ISSN	1573-2509 ; 0920-9964
ISSN (online)	1573-2509
ISSN	0920-9964
DOI	10.1016/j.schres.2019.07.042
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Zs.MO 543: Show issues

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Article ; Online: Subjective sleep parameters in prodromal Alzheimer's disease: a case-control study.

Borges, Conrado R / Piovezan, Ronaldo D / Poyares, Dalva R / Busatto Filho, Geraldo / Studart-Neto, Adalberto / Coutinho, Artur M / Tufik, Sergio / Nitrini, Ricardo / Brucki, Sonia M

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)

2021 Volume 43, Issue 5, Page(s) 510–513

Abstract: Objective: People with Alzheimer's disease (AD) dementia have impaired sleep. However, the characteristics of sleep in the early stages of AD are not well known, and studies with the aid of biomarkers are lacking. We assessed the subjective sleep ... ...

Abstract	Objective: People with Alzheimer's disease (AD) dementia have impaired sleep. However, the characteristics of sleep in the early stages of AD are not well known, and studies with the aid of biomarkers are lacking. We assessed the subjective sleep characteristics of non-demented older adults and compared their amyloid profiles. Methods: We enrolled 30 participants aged ≥ 60 years, with no dementia or major clinical and psychiatric diseases. They underwent [11C]PiB-PET-CT, neuropsychological evaluations, and completed two standardized sleep assessments (Pittsburgh Sleep Quality Inventory and Epworth Sleep Scale). Results: Comparative analysis of subjective sleep parameters across the two groups showed longer times in bed (p = 0.024) and reduced sleep efficiency (p = 0.05) in individuals with positive amyloid. No differences in other subjective sleep parameters were observed. We also found that people with multiple-domain mild cognitive impairment (MCI) had shorter self-reported total sleep times (p = 0.034) and worse overall sleep quality (p = 0.027) compared to those with single-domain MCI. Conclusions: Older adults testing positive for amyloid had a longer time in bed and lower sleep efficiency, regardless of cognitive status. In parallel, individuals with multiple-domain MCI reported shorter sleep duration and lower overall sleep quality.
MeSH term(s)	Aged ; Alzheimer Disease/diagnostic imaging ; Aniline Compounds ; Case-Control Studies ; Cognitive Dysfunction/diagnostic imaging ; Humans ; Positron Emission Tomography Computed Tomography ; Positron-Emission Tomography ; Sleep ; Thiazoles
Chemical Substances	Aniline Compounds ; Thiazoles
Language	English
Publishing date	2021-03-13
Publishing country	Brazil
Document type	Journal Article
ISSN	1809-452X
ISSN (online)	1809-452X
DOI	10.1590/1516-4446-2020-1503
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Article ; Online: Effects of exercise training on brain metabolism and cognitive functioning in sleep apnea.

Ueno-Pardi, Linda M / Souza-Duran, Fabio L / Matheus, Larissa / Rodrigues, Amanda G / Barbosa, Eline R F / Cunha, Paulo J / Carneiro, Camila G / Costa, Naomi A / Ono, Carla R / Buchpiguel, Carlos A / Negrão, Carlos E / Lorenzi-Filho, Geraldo / Busatto-Filho, Geraldo

Scientific reports

2022 Volume 12, Issue 1, Page(s) 9453

Abstract: Impaired glucose metabolism reflects neuronal/synaptic dysfunction and cognitive function decline in patients with obstructive sleep apnea (OSA). The study investigated the extent to which exercise training (ET) improves cerebral metabolic glucose rate ( ... ...

Abstract	Impaired glucose metabolism reflects neuronal/synaptic dysfunction and cognitive function decline in patients with obstructive sleep apnea (OSA). The study investigated the extent to which exercise training (ET) improves cerebral metabolic glucose rate (CMRgl) and cognitive function in patients with OSA. Patients with moderate to severe OSA were randomly assigned to ET (3 times/week, n = 23) or no intervention (control, n = 24). Echocardiography and apolipoprotein ε4 (APOEε4) genotyping were obtained at baseline. Both groups underwent cardiopulmonary exercise testing, polysomnography, cognitive tests, brain magnetic resonance imaging, and
MeSH term(s)	Brain/diagnostic imaging ; Cognition ; Exercise ; Humans ; Sleep Apnea, Obstructive ; Tomography, X-Ray Computed
Language	English
Publishing date	2022-06-08
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-13115-2
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Article ; Online: Depression and temporal lobe epilepsy represent an epiphenomenon sharing similar neural networks: clinical and brain structural evidences.

Valente, Kette D R / Busatto Filho, Geraldo

Arquivos de neuro-psiquiatria

2013 Volume 71, Issue 3, Page(s) 183–190

Abstract: The relationship between depression and epilepsy has been known since ancient times, however, to date, it is not fully understood. The prevalence of psychiatric disorders in persons with epilepsy is high compared to general population. It is assumed that ...

Abstract	The relationship between depression and epilepsy has been known since ancient times, however, to date, it is not fully understood. The prevalence of psychiatric disorders in persons with epilepsy is high compared to general population. It is assumed that the rate of depression ranges from 20 to 55% in patients with refractory epilepsy, especially considering those with temporal lobe epilepsy caused by mesial temporal sclerosis. Temporal lobe epilepsy is a good biological model to understand the common structural basis between depression and epilepsy. Interestingly, mesial temporal lobe epilepsy and depression share a similar neurocircuitry involving: temporal lobes with hippocampus, amygdala and entorhinal and neocortical cortex; the frontal lobes with cingulate gyrus; subcortical structures, such as basal ganglia and thalamus; and the connecting pathways. We provide clinical and brain structural evidences that depression and epilepsy represent an epiphenomenon sharing similar neural networks.
MeSH term(s)	Brain/pathology ; Brain/physiopathology ; Depression/pathology ; Depression/physiopathology ; Epilepsy, Temporal Lobe/pathology ; Epilepsy, Temporal Lobe/physiopathology ; Humans ; Nerve Net/pathology ; Nerve Net/physiopathology ; Neuroimaging
Language	English
Publishing date	2013-03-26
Publishing country	Brazil
Document type	Journal Article ; Review
ZDB-ID	418916-4
ISSN	1678-4227 ; 0004-282X
ISSN (online)	1678-4227
ISSN	0004-282X
DOI	10.1590/s0004-282x2013000300011
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Article ; Online: Episodic Memory, Hippocampal Volume, and Function for Classification of Mild Cognitive Impairment Patients Regarding Amyloid Pathology.

Miotto, Eliane Correa / Brucki, Sonia Maria Dozzi / Cerqueira, Carlos T / Bazán, Paulo R / Silva, Geise Aline de Almeida / Martin, Maria da Graça M / da Silveira, Paula Squarzoni / Faria, Daniele de Paula / Coutinho, Artur Martins / Buchpiguel, Carlos Alberto / Busatto Filho, Geraldo / Nitrini, Ricardo

Journal of Alzheimer's disease : JAD

2022 Volume 89, Issue 1, Page(s) 181–192

Abstract: Background: Previous studies of hippocampal function and volume related to episodic memory deficits in patients with amnestic mild cognitive impairment (aMCI) have produced mixed results including increased or decreased activity and volume. However, ... ...

Abstract	Background: Previous studies of hippocampal function and volume related to episodic memory deficits in patients with amnestic mild cognitive impairment (aMCI) have produced mixed results including increased or decreased activity and volume. However, most of them have not included biomarkers, such as amyloid-β (Aβ) deposition which is the hallmark for early identification of the Alzheimer's disease continuum. Objective: We investigated the role of Aβ deposition, functional hippocampal activity and structural volume in aMCI patients and healthy elderly controls (HC) using a new functional MRI (fMRI) ecological episodic memory task. Methods: Forty-six older adults were included, among them Aβ PET PIB positive (PIB+) aMCI (N = 17), Aβ PET PIB negative (PIB-) aMCI (N = 15), and HC (N = 14). Hippocampal volume and function were analyzed using Freesurfer v6.0 and FSL for news headlines episodic memory fMRI task, and logistic regression for group classification in conjunction with episodic memory task and traditional neuropsychological tests. Results: The aMCI PIB+ and PIB-patients showed significantly worse performance in relation to HC in most traditional neuropsychological tests and within group difference only on story recall and the ecological episodic memory fMRI task delayed recall. The classification model reached a significant accuracy (78%) and the classification pattern characterizing the PIB+ included decreased left hippocampal function and volume, increased right hippocampal function and volume, and worse episodic memory performance differing from PIB-which showed increased left hippocampus volume. Conclusion: The main findings showed differential neural correlates, hippocampal volume and function during episodic memory in aMCI patients with the presence of Aβ deposition.
MeSH term(s)	Aged ; Alzheimer Disease/pathology ; Amyloid/metabolism ; Amyloid beta-Peptides/metabolism ; Amyloidosis/pathology ; Cognitive Dysfunction ; Hippocampus/pathology ; Humans ; Magnetic Resonance Imaging/methods ; Memory, Episodic ; Neuropsychological Tests
Chemical Substances	Amyloid ; Amyloid beta-Peptides
Language	English
Publishing date	2022-07-23
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1440127-7
ISSN	1875-8908 ; 1387-2877
ISSN (online)	1875-8908
ISSN	1387-2877
DOI	10.3233/JAD-220100
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Electroconvulsive therapy practice during the COVID-19 pandemic

Bellini, Helena / Cretaz, Eric / Rigonatti, Luiz Felipe / Conto, Carla Dominique Rodrigues De / Melzer-Ribeiro, Débora Luciana / Busatto-Filho, Geraldo / Brunoni, André Russowsky / Gallucci-Neto, José

Clinics v.75 2020

2020

Keywords	covid19
Language	English
Publishing date	2020-01-01
Publisher	Faculdade de Medicina / USP
Publishing country	br
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A anatomia estrutural e funcional da esquizofrenia

Busatto Filho Geraldo

Revista Brasileira de Psiquiatria, Vol 22, Iss suppl.1, Pp 9-

achados de neuropatologia e neuroimagem

2000 Volume 11

Keywords	Psychiatry ; RC435-571 ; Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Psychiatry ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	2000-01-01T00:00:00Z
Publisher	Associação Brasileira de Psiquiatria - ABP
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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