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  1. Article ; Online: Burnout in gastroenterology: raise awareness and identify drivers.

    Buscarini, Elisabetta / Gecse, Krisztina B / Tiniakos, Dina

    United European gastroenterology journal

    2021  Volume 9, Issue 1, Page(s) 128

    MeSH term(s) Burnout, Professional/epidemiology ; Burnout, Psychological/epidemiology ; Gastroenterology ; Humans
    Language English
    Publishing date 2021-02-22
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2728585-6
    ISSN 2050-6414 ; 2050-6406
    ISSN (online) 2050-6414
    ISSN 2050-6406
    DOI 10.1177/2050640620977151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A stubborn fever.

    Pedaci, Marianna / Londoni, Claudio / Bertè, Roberto / Buscarini, Elisabetta

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2021  Volume 54, Issue 10, Page(s) 1444–1445

    MeSH term(s) Fever/etiology ; Humans
    Language English
    Publishing date 2021-10-31
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2021.09.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Burnout among gastroenterologists: How to manage and prevent it.

    Buscarini, Elisabetta / Gecse, Krisztina B / Tiniakos, Dina

    United European gastroenterology journal

    2020  Volume 8, Issue 7, Page(s) 832–834

    Language English
    Publishing date 2020-07-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2728585-6
    ISSN 2050-6414 ; 2050-6406
    ISSN (online) 2050-6414
    ISSN 2050-6406
    DOI 10.1177/2050640620943466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Long pentraxin 3 as a marker of COVID-19 severity: evidences and perspectives.

    Assandri, Roberto / Accordino, Silvia / Canetta, Ciro / Buscarini, Elisabetta / Scartabellati, Alessandro / Tolassi, Chiara / Serana, Federico

    Biochemia medica

    2022  Volume 32, Issue 2, Page(s) 20901

    Abstract: Introduction: Several laboratory tests are characteristically altered in Coronavirus Disease 2019 (COVID-19), but are not totally accurate in predicting the disease outcome. The long pentraxin 3 (PTX3) is quickly released directly at inflammation sites ... ...

    Abstract Introduction: Several laboratory tests are characteristically altered in Coronavirus Disease 2019 (COVID-19), but are not totally accurate in predicting the disease outcome. The long pentraxin 3 (PTX3) is quickly released directly at inflammation sites by many immune cell types. Previous studies have shown that PTX3 correlated with disease severity in various inflammatory conditions. Our study investigated the use of PTX3 as a potential marker of COVID-19 severity and compared its performance in detecting a more severe form of the disease with that of routine laboratory parameters.
    Materials and methods: Stored serum samples of RT-PCR confirmed COVID-19 cases that had been obtained at hospital admission were retrospectively analysed. Intensive care unit (ICU) stay was considered a surrogate endpoint of severe COVID-19. Pentraxin 3 was measured by a commercial enzyme-linked immunosorbent assay.
    Results: A total of 96 patients were recruited from May 1st, 2020 to June 30th, 2020; 75/96 were transferred to ICU. Pentraxin 3 was higher in ICU
    Conclusion: High values of PTX3 predict a more severe COVID-19.
    MeSH term(s) Biomarkers ; C-Reactive Protein/metabolism ; COVID-19/diagnosis ; Ferritins ; Humans ; ROC Curve ; Retrospective Studies ; Serum Amyloid P-Component
    Chemical Substances Biomarkers ; Serum Amyloid P-Component ; PTX3 protein (148591-49-5) ; C-Reactive Protein (9007-41-4) ; Ferritins (9007-73-2)
    Language English
    Publishing date 2022-04-15
    Publishing country Croatia
    Document type Journal Article
    ZDB-ID 1208725-7
    ISSN 1846-7482 ; 1330-0962
    ISSN (online) 1846-7482
    ISSN 1330-0962
    DOI 10.11613/BM.2022.020901
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Response to Bevacizumab for the treatment of Rendu-Osler disease-A note of caution.

    Dupuis-Girod, Sophie / Buscarini, Elisabetta

    Liver international : official journal of the International Association for the Study of the Liver

    2017  Volume 37, Issue 6, Page(s) 928

    Language English
    Publishing date 2017-06
    Publishing country United States
    Document type Letter
    ZDB-ID 2102783-3
    ISSN 1478-3231 ; 1478-3223
    ISSN (online) 1478-3231
    ISSN 1478-3223
    DOI 10.1111/liv.13385
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Hereditary hemorrhagic telangiectasia: to transplant or not to transplant?

    Dupuis-Girod, Sophie / Buscarini, Elisabetta

    Liver international : official journal of the International Association for the Study of the Liver

    2016  Volume 36, Issue 12, Page(s) 1741–1744

    Abstract: This report comments the case reported by Muller et al. which describes a combination of at least two different indications for orthotopic liver transplant (OLT) in a same patient: hepatocarcinoma and HHT complicated with severe liver involvement and ... ...

    Abstract This report comments the case reported by Muller et al. which describes a combination of at least two different indications for orthotopic liver transplant (OLT) in a same patient: hepatocarcinoma and HHT complicated with severe liver involvement and high output cardiac failure. This case report highlighted that the clear time for OLT in HHT can be difficult to determine. In HHT, if intensive medical approach is not efficient, OLT, has to be considered. In the case of Muller et al., the patient was correctly listed for OLT for a single hepatocellular carcinoma, however, he did not receive a sufficient priority so as to avoid worsening of liver vascular malformations complications. Bevacizumab may be a therapeutic option in the treatment of complicated liver VMs in HHT, However, the recurrence of symptoms after withdrawal of the drug make it unsuitable as a replacement for OLT in the cure of complicated liver VMs in HHT. In the case reported by Muller et al. the right "OLT window" after bevacizumab was lost. The right time for OLT in severe complicated liver VMs in HHT does exist but, as this case illustrates, it can be very difficult to determine. As OLT is a radical cure for liver VMs, with excellent outcomes, it should be the therapeutic choice in patients under the age of 65 years. Bevacizumab may be an interesting option, either for patients over the age of 65 years, or those who are poor candidates for surgery; if these latter respond to bevacizumab they should be re- evaluated for OLT (with a "fast- track") as the prognosis of severe complicated liver VMs is very poor.
    MeSH term(s) Bevacizumab ; Humans ; Liver Neoplasms ; Liver Transplantation ; Male ; Neoplasm Recurrence, Local ; Telangiectasia, Hereditary Hemorrhagic
    Chemical Substances Bevacizumab (2S9ZZM9Q9V)
    Language English
    Publishing date 2016-11-18
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2102783-3
    ISSN 1478-3231 ; 1478-3223
    ISSN (online) 1478-3231
    ISSN 1478-3223
    DOI 10.1111/liv.13210
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Second-generation thrombopoietin receptor agonists: New players in the management of cirrhotic patients undergoing therapeutic endoscopy?

    Radaelli, Franco / Hassan, Cesare / Buscarini, Elisabetta / Dinis-Ribeiro, Mario / Fuccio, Lorenzo

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2021  Volume 53, Issue 10, Page(s) 1362–1363

    MeSH term(s) Cinnamates/therapeutic use ; Endoscopy/methods ; Humans ; Liver Cirrhosis/complications ; Receptors, Thrombopoietin/agonists ; Receptors, Thrombopoietin/therapeutic use ; Surveys and Questionnaires ; Thiazoles/therapeutic use ; Thiophenes/therapeutic use ; Thrombocytopenia/drug therapy ; Thrombocytopenia/etiology
    Chemical Substances Cinnamates ; Receptors, Thrombopoietin ; Thiazoles ; Thiophenes ; avatrombopag (3H8GSZ4SQL) ; lusutrombopag (6LL5JFU42F)
    Language English
    Publishing date 2021-06-02
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2021.05.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Manual of diagnostic ultrasound

    Lutz, Harald / Buscarini, Elisabetta

    2011  

    Institution World Health Organization
    Author's details World Health Organization
    MeSH term(s) Ultrasonography/methods ; Diagnostic Imaging/methods
    Language English
    Dates of publication 2011-9999
    Size v. :, ill. ;, 24 cm.
    Edition 2nd ed.
    Publisher World Health Organization
    Publishing place Geneva, Switzerland
    Document type Book
    Note Edited by Harald T. Lutz and Elisabetta Buscarini.
    ISBN 9789241547451 ; 9241547456 ; 9789241548540 ; 9241548541
    Database Catalogue of the US National Library of Medicine (NLM)

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  9. Article ; Online: Effect of Tofacitinib on One-Year Colectomy Risk in Anti-TNF Refractory Ulcerative Colitis: A Prospective Multicenter Italian Study.

    Carvalhas Gabrielli, Anna Maria / Ferretti, Francesca / Monico, Camilla Maria / Tombetti, Enrico / Maconi, Giovanni / Romeo, Samanta / Piazza O Sed, Nicole / Caprioli, Flavio / Mazzola, Anna Maria / Alicante, Saverio / Bertè, Roberto / Lolli, Elisabetta / Scribano, Maria Lia / Buscarini, Elisabetta / Ricci, Chiara / Carmagnola, Stefania / Ardizzone, Sandro / Cannatelli, Rosanna

    Digestive diseases and sciences

    2024  

    Abstract: Background: Tofacitinib is an oral Janus kinase inhibitor recently approved to induce and maintain remission in ulcerative colitis (UC).: Aims: Considering the number of anti-TNF non-responders, this study aims to assess the effectiveness and safety ... ...

    Abstract Background: Tofacitinib is an oral Janus kinase inhibitor recently approved to induce and maintain remission in ulcerative colitis (UC).
    Aims: Considering the number of anti-TNF non-responders, this study aims to assess the effectiveness and safety of tofacitinib in a cohort of multi-failure patients with moderate-to-severe UC at 52 weeks.
    Methods: From January 2021 to March 2023, we performed a prospective multicenter study observing adult patients with moderate-to-severe UC starting tofacitinib after an anti-TNF failure for a 52-week-long period. Effectiveness and safety were assessed in terms of colectomy rate, clinical remission and response, endoscopic remission, steroid-free clinical remission, and rate of adverse events.
    Results: We included 58 patients with UC with an age of 42 ± 14.4 years, 59% males, 96.6% left-sided or pancolitis, who were failure to a single (65.5%) or more than one anti-TNF (34.5%). Only 6 (10.3%) patients underwent colectomy. Colectomy was clinically associated with the necessity and the number of extra cycles of tofacitinib 10 mg bid at W8 (p = 0.023) and W24 (p = 0.004), and with a higher partial Mayo score at W8 (p = 0.025). At W52, clinical remission, clinical response, and steroid-free clinical remission were 53.4%, 43.1%, and 48.3%, respectively. Of 22 performed colonoscopies at W52, 11 (50%) showed endoscopic remission. Adverse events occurred in 14 (24.1%) patients, but only 2 (3.4%) led to tofacitinib discontinuation.
    Conclusions: In a real-life setting of patients with anti-TNF refractory UC, tofacitinib has proved to be effective in preventing colectomy and inducing clinical and endoscopic remission at 52 weeks with a good safety profile.
    Language English
    Publishing date 2024-03-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 304250-9
    ISSN 1573-2568 ; 0163-2116
    ISSN (online) 1573-2568
    ISSN 0163-2116
    DOI 10.1007/s10620-024-08394-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Laboratory markers included in the Corona Score can identify false negative results on COVID-19 RT-PCR in the emergency room.

    Assandri, Roberto / Canetta, Ciro / Viganò, Giovanni / Buscarini, Elisabetta / Scartabellati, Alessandro / Montanelli, Alessandro

    Biochemia medica

    2020  Volume 30, Issue 3, Page(s) 30402

    Abstract: After December 2019 outbreak in China, the novel Coronavirus infection (COVID-19) has very quickly overflowed worldwide. Infection causes a clinical syndrome encompassing a wide range of clinical features, from asymptomatic or oligosymptomatic course to ... ...

    Abstract After December 2019 outbreak in China, the novel Coronavirus infection (COVID-19) has very quickly overflowed worldwide. Infection causes a clinical syndrome encompassing a wide range of clinical features, from asymptomatic or oligosymptomatic course to acute respiratory distress and death. In a very recent work we preliminarily observed that several laboratory tests have been shown as characteristically altered in COVID-19. We aimed to use the Corona score, a validated point-based algorithm to predict the likelihood of COVID-19 infection in patients presenting at the Emergency rooms. This approach combines chest images-relative score and several laboratory parameters to classify emergency room patients. Corona score accuracy was satisfactory, increasing the detection of positive patients' rate.
    MeSH term(s) Betacoronavirus/isolation & purification ; Biomarkers/metabolism ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Cohort Studies ; Coronavirus Infections/diagnosis ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/metabolism ; Emergency Service, Hospital/standards ; False Negative Reactions ; Humans ; Negative Results ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/metabolism ; Reproducibility of Results ; Reverse Transcriptase Polymerase Chain Reaction/methods ; Reverse Transcriptase Polymerase Chain Reaction/standards ; SARS-CoV-2 ; Tomography, X-Ray Computed/methods ; Tomography, X-Ray Computed/standards
    Chemical Substances Biomarkers
    Keywords covid19
    Language English
    Publishing date 2020-08-05
    Publishing country Croatia
    Document type Journal Article
    ZDB-ID 1208725-7
    ISSN 1846-7482 ; 1330-0962
    ISSN (online) 1846-7482
    ISSN 1330-0962
    DOI 10.11613/BM.2020.030402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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