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Book ; Online: Buch-Aisthesis

Busch, Christopher / Ruf, Oliver

Philologie und Gestaltungsdiskurs

(Medien- und Gestaltungsästhetik)

2022

Series title	Medien- und Gestaltungsästhetik
Keywords	Media studies ; Literary studies: general ; Industrial / commercial art & design ; Ästhetik ; Buch ; Buchgestaltung ; Gestaltung ; Angewandte Philologie ; Material Studies ; Medien ; Literatur ; Design ; Medienästhetik ; Allgemeine Literaturwissenschaft ; Analoge Medien ; Medienwissenschaft ; Aesthetics ; Book ; Book Desgin ; Shaping ; Applied Philology ; Media ; Literature ; Media Aesthetics ; Literary Studies ; Analogue Media ; Media Studies
Language	German
Size	1 electronic resource (250 pages)
Publisher	transcript Verlag
Publishing place	Bielefeld
Document type	Book ; Online
Note	German
HBZ-ID	HT030380259
ISBN	9783732861088 ; 3732861082
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book: Aktionsleitfaden - Zukunftschancen für Freund Baum

Schultheiß, Helmut / Frobel, Kai / Mühlleitner, Daniel / Busch, Christopher

mit Basisinformationen, Handlungsempfehlungen und Aktionsvorschlägen für die Erhaltung, Pflege und Neupflanzung von Bäumen im Siedlungsbereich

2017

Title variant	Zukunftschancen für Freund Baum
Institution	Bund Naturschutz in Bayern
Author's details	Autor: Helmut Schultheiß; Co-Autoren: Dr. Kai Frobel, Dr. Daniel Mühlleitner, Christopher Busch ; BUND Naturschutz in Bayern e.V
Keywords	Baum ; Baumschutz ; Bayern ; Bund Naturschutz ; Naturschutz
Language	German
Size	167 Seiten, Illustrationen, 30 cm, 556 g
Publisher	BUND Naturschutz in Bayern e.V
Publishing place	Nürnberg
Publishing country	Germany
Document type	Book
HBZ-ID	HT019841152
ISBN	978-3-9808986-7-6 ; 3-9808986-7-9
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

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Book: The diffusion of cattle ranching and deforestation

Busch, Christopher B. / Vance, Colin

prospects for a hollow frontier in Mexico's Yucatán

(Ruhr economic papers ; 242)

2011

Author's details	Christopher B. Busch and Colin Vance
Series title	Ruhr economic papers ; 242
Collection
Language	English
Size	30 S.
Publisher	RWI
Publishing place	Bochum
Publishing country	Germany
Document type	Book
HBZ-ID	HT016751260
ISBN	978-3-86788-278-1 ; 3-86788-278-9
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

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118/99	available for loan (reading room)	Freihandmagazin (U1)

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Article ; Online: A Comparison of Additional Benefit Assessment Methods for Time-to-Event Endpoints Using Hazard Ratio Point Estimates or Confidence Interval Limits by Means of a Simulation Study.

Büsch, Christopher A / Kirchner, Marietta / Behnisch, Rouven / Kieser, Meinhard

Medical decision making : an international journal of the Society for Medical Decision Making

2024 , Page(s) 272989X241239928

Abstract: Background: For time-to-event endpoints, three additional benefit assessment methods have been developed aiming at an unbiased knowledge about the magnitude of clinical benefit of newly approved treatments. The American Society of Clinical Oncology ( ... ...

Abstract	Background: For time-to-event endpoints, three additional benefit assessment methods have been developed aiming at an unbiased knowledge about the magnitude of clinical benefit of newly approved treatments. The American Society of Clinical Oncology (ASCO) defines a continuous score using the hazard ratio point estimate (HR-PE). The European Society for Medical Oncology (ESMO) and the German Institute for Quality and Efficiency in Health Care (IQWiG) developed methods with an ordinal outcome using lower and upper limits of the 95% HR confidence interval (HR-CI), respectively. We describe all three frameworks for additional benefit assessment aiming at a fair comparison across different stakeholders. Furthermore, we determine which ASCO score is consistent with which ESMO/IQWiG category. Methods: In a comprehensive simulation study with different failure time distributions and treatment effects, we compare all methods using Spearman's correlation and descriptive measures. For determination of ASCO values consistent with categories of ESMO/IQWiG, maximizing weighted Cohen's Kappa approach was used. Results: Our research depicts a high positive relationship between ASCO/IQWiG and a low positive relationship between ASCO/ESMO. An ASCO score smaller than 17, 17 to 20, 20 to 24, and greater than 24 corresponds to ESMO categories. Using ASCO values of 21 and 38 as cutoffs represents IQWiG categories. Limitations: We investigated the statistical aspects of the methods and hence implemented slightly reduced versions of all methods. Conclusions: IQWiG and ASCO are more conservative than ESMO, which often awards the maximal category independent of the true effect and is at risk of overcompensating with various failure time distributions. ASCO has similar characteristics as IQWiG. Delayed treatment effects and underpowered/overpowered studies influence all methods in some degree. Nevertheless, ESMO is the most liberal one. Highlights: For the additional benefit assessment, the American Society of Clinical Oncology (ASCO) uses the hazard ratio point estimate (HR-PE) for their continuous score. In contrast, the European Society for Medical Oncology (ESMO) and the German Institute for Quality and Efficiency in Health Care (IQWiG) use the lower and upper 95% HR confidence interval (HR-CI) to specific thresholds, respectively. ESMO generously assigns maximal scores, while IQWiG is more conservative.This research provides the first comparison between IQWiG and ASCO and describes all three frameworks for additional benefit assessment aiming for a fair comparison across different stakeholders. Furthermore, thresholds for ASCO consistent with ESMO and IQWiG categories are determined, enabling a comparison of the methods in practice in a fair manner.IQWiG and ASCO are the more conservative methods, while ESMO awards high percentages of maximal categories, especially with various failure time distributions. ASCO has similar characteristics as IQWiG. Delayed treatment effects and under/-overpowered studies influence all methods. Nevertheless, ESMO is the most liberal one. An ASCO score smaller than 17, 17 to 20, 20 to 24, and greater than 24 correspond to the categories of ESMO. Using ASCO values of 21 and 38 as cutoffs represents categories of IQWiG.
Language	English
Publishing date	2024-05-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	604497-9
ISSN	1552-681X ; 0272-989X
ISSN (online)	1552-681X
ISSN	0272-989X
DOI	10.1177/0272989X241239928
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Article ; Online: Ceramic anterior veneer restorations in periodontally compromised patients: A retrospective study.

Gaß, Johanna A / Büsch, Christopher / Körner, Gerd A / Bäumer, Amelie M

Clinical advances in periodontics

2023 Volume 13, Issue 4, Page(s) 266–275

Abstract: Background: Successful periodontal therapy can lead to poor esthetic results, especially in the anterior region, for which there are treatment options such as direct composite or indirect veneer restorations. Until now, there are no data describing the ... ...

Abstract	Background: Successful periodontal therapy can lead to poor esthetic results, especially in the anterior region, for which there are treatment options such as direct composite or indirect veneer restorations. Until now, there are no data describing the long-term results of veneer restorations in periodontally treated patients. The aim of this retrospective study was to evaluate the outcome of anterior porcelain veneer restorations in periodontally compromised and noncompromised patients. Methods: Periodontally healthy and periodontally compromised patients, who had received anterior veneer restorations at least 5 years ago, were invited to a follow-up examination. Groups were divided according to their periodontal diagnosis (periodontally healthy, stage I/II, stage III/IV). Tooth loss, veneer loss, biologic parameters, and complication rates were examined. Also, veneers were evaluated according to modified United States Public Health Service criteria. Results: A total of 68 patients with 312 veneers were examined with a mean follow-up time of 8 years. Veneered teeth in patients with periodontitis stage III/IV showed no difference regarding tooth-specific, overall, and functional veneer survival when compared to periodontally healthy patients (Kaplan-Meier analyses). In Cox regression analysis, follow-up time had an impact on complications and veneer loss, whereas periodontal diagnosis showed no significant influence on the survival of restorations. Comparative tests showed that patients with severe periodontitis at baseline have slightly lower veneer survival rates after 8 years and slightly higher complication rates after 13 years. Conclusion: Long-term results and complication rates of veneer restorations in periodontally compromised patients are comparable to periodontally healthy patients over a mean follow-up of 8 years.
MeSH term(s)	United States ; Humans ; Dental Porcelain ; Retrospective Studies ; Esthetics, Dental ; Ceramics ; Periodontitis/complications ; Periodontitis/therapy
Chemical Substances	Dental Porcelain (12001-21-7)
Language	English
Publishing date	2023-06-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2670204-6
ISSN	2163-0097 ; 2573-8046
ISSN (online)	2163-0097
ISSN	2573-8046
DOI	10.1002/cap.10246
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Article ; Online: A Comprehensive Comparison of Additional Benefit Assessment Methods Applied by Institute for Quality and Efficiency in Health Care and European Society for Medical Oncology for Time-to-Event Endpoints After Significant Phase III Trials-A Simulation Study.

Büsch, Christopher A / Krisam, Johannes / Kieser, Meinhard

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

2022

Abstract: Objectives: After a successful Marketing Authorization Application for clinical trials with time-to-event endpoints, the degree of the added benefit from new treatments remains unknown and needs to be assessed. Unfortunately, until now no clear ... ...

Abstract	Objectives: After a successful Marketing Authorization Application for clinical trials with time-to-event endpoints, the degree of the added benefit from new treatments remains unknown and needs to be assessed. Unfortunately, until now no clear definition for added benefit determination of a treatment exists. Nevertheless, European authorities / societies have developed 2 "additional benefit assessment" methods, which have up to now not been compared: the European Society for Medical Oncology (ESMO) developed a dual rule considering relative and absolute benefit. The German Institute for Quality and Efficiency in Health Care (IQWiG) developed a method using upper 95% hazard ratio confidence interval. Methods: We evaluate and compare both methods in an extensive simulation study including different censoring rates, failure time distributions, and treatment effects for sample size calculation. The methods' performance is assessed via Receiver Operating Characteristic curves, Spearman correlation, and percentage of achieved maximal scores. Results: The results show that IQWiG's method has in many situations a lower maximal scoring proportion than ESMO's rule, that is, up to 28.5% versus 94.7%. Various failure time distributions lead to strongly changed maximal scoring percentages for ESMO. High positive correlation between the methods is present for moderate treatment effects. Conclusions: IQWiG's method is usually more conservative than ESMO's. ESMO's rule tends to be more susceptible for various failure time distributions. Using the lower confidence interval limit seems to be a better solution resulting in a higher true-positive rate without increasing the false-positive rate. Thus, IQWiG's method might need to be adapted accordingly to achieve a better overall classification.
Language	English
Publishing date	2022-06-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	1471745-1
ISSN	1524-4733 ; 1098-3015
ISSN (online)	1524-4733
ISSN	1098-3015
DOI	10.1016/j.jval.2022.05.015
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Article ; Online: Peri-implant health after microvascular head and neck reconstruction-A retrospective analysis.

Hoffmann, Korbinian Jochen / Büsch, Christopher / Moratin, Julius / Ristow, Oliver / Hoffmann, Jürgen / Mertens, Christian

Clinical oral implants research

2023 Volume 35, Issue 2, Page(s) 187–200

Abstract: Introduction: Prosthodontic rehabilitation after reconstruction with microvascular revascularized free flaps following ablative tumor surgery is challenging due to the altered anatomical and functional conditions. The aim of this retrospective study was ...

Abstract	Introduction: Prosthodontic rehabilitation after reconstruction with microvascular revascularized free flaps following ablative tumor surgery is challenging due to the altered anatomical and functional conditions. The aim of this retrospective study was to determine whether the type of graft and the type of peri-implant tissue have an effect on peri-implant inflammatory parameters and implant survival. Materials and methods: Patients who received a free flap reconstruction with subsequent implant-prosthetic rehabilitation between 2010 and 2022 were retrospectively included. The primary outcome variable was the probing depth (PPD) at a minimum of 1 year after completion of prosthetic restoration. Predictive variables were type of free flap, emergence profile, and history of radiation. Results: Seventy-one patients after free flap reconstruction were included in the analysis. At a minimum of 24 months after implant insertion the primary outcome, PPD showed no clinically relevant differences between the types of free flaps used. The emergence profile through a skin island resulted in an increase in BOP compared to native mucosa in the descriptive analysis (p-value > .05). The analysis showed a 5-year implant survival of 96.2% (95% CI: 0.929-0.996) in cases without irradiation and 87.6% (95% CI: 0.810-0.948) with irradiation of the region evaluated (p-value .034). Conclusion: Flap and associated soft tissue type had no significant effect on 5-year implant survival or peri-implant inflammatory parameters. However, the large heterogeneity of the patient population indicates that further prolonged studies are required for a more differentiated assessment of the long-term success.
MeSH term(s)	Humans ; Dental Implantation, Endosseous/methods ; Dental Implants/adverse effects ; Retrospective Studies ; Free Tissue Flaps/surgery ; Plastic Surgery Procedures
Chemical Substances	Dental Implants
Language	English
Publishing date	2023-11-27
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	1067626-0
ISSN	1600-0501 ; 0905-7161
ISSN (online)	1600-0501
ISSN	0905-7161
DOI	10.1111/clr.14214
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Article ; Online: Long-term apical bone gain after implant placement combined with internal sinus-floor elevation without graft.

Rammelsberg, Peter / Pahle, Julia / Büsch, Christopher / Zenthöfer, Andreas

BMC oral health

2020 Volume 20, Issue 1, Page(s) 197

Abstract: Background: To assess changes in apical bone height/bone gain over up to 8 years after implant placement combined with simultaneous internal sinus-floor elevation (ISFE) without use of graft.: Methods: 217 implants were placed in combination with ... ...

Abstract	Background: To assess changes in apical bone height/bone gain over up to 8 years after implant placement combined with simultaneous internal sinus-floor elevation (ISFE) without use of graft. Methods: 217 implants were placed in combination with graft-free ISFE and successfully healed in the posterior maxilla of 138 patients. Radiographs after surgery across an evaluation time of up to 8 years were analyzed. Changes in apical and marginal bone height related to the implants were measured. Differences in bone height over the study period were evaluated by use of Wilcoxon tests. To identify possible influencing factors on apical bone gain and marginal bone loss, backward linear regression variable selections and linear mixed regression models were performed. Results: At the apical aspects of the implants, significant mean vertical bone gain of 2.4 mm (mesial) and 2.6 mm (distal) was observed after 6 months (p < 0.05). Radiographic analysis yielded additional bone gain of up to approximately 3.5 mm over the study period. Small initial bone height was crossed with more pronounced apical bone gain (p < 0.05). Conclusions: If implants are placed combined with graft-free ISFE, significant vertical bone gain, especially in the first year post-op, can be expected. Smaller initial bone height is associated with a higher likelihood for greater bone gain.
MeSH term(s)	Adult ; Aged ; Dental Implantation, Endosseous/adverse effects ; Dental Implants/adverse effects ; Female ; Humans ; Male ; Maxilla/surgery ; Maxillary Sinus ; Middle Aged ; Sinus Floor Augmentation ; Treatment Outcome
Chemical Substances	Dental Implants
Language	English
Publishing date	2020-07-09
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2091511-1
ISSN	1472-6831 ; 1472-6831
ISSN (online)	1472-6831
ISSN	1472-6831
DOI	10.1186/s12903-020-01178-4
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Article ; Online: The effect of transcrestal sinus-floor elevation without graft on the long-term prognosis of maxillary implants.

Rammelsberg, Peter / Kilian, Samuel / Büsch, Christopher / Kappel, Stefanie

Journal of clinical periodontology

2020 Volume 47, Issue 5, Page(s) 640–648

Abstract: Aim: To evaluate the effects of (a) transcrestal sinus-floor elevation (TSFE) and (b) residual bone height on long-term implant survival.: Materials and methods: Chi-squared and t tests were used for descriptive comparison of the groups. Kaplan-Meier ...

Abstract	Aim: To evaluate the effects of (a) transcrestal sinus-floor elevation (TSFE) and (b) residual bone height on long-term implant survival. Materials and methods: Chi-squared and t tests were used for descriptive comparison of the groups. Kaplan-Meier survival curves and corresponding log-rank tests were used to investigate implant survival over time. Multivariable Cox regressions were performed for the total population and experimental group. Results: A total of 634 patients received 648 implants with TSFE, while 674 implants without TSFE served as controls. Thirty implant failures occurred in the experimental group and 28 in the control group. Ten-year Kaplan-Meier survival curves for the 157 implants (24.3%) still under observation showed a probability of survival of 93.7% for the implants with TSFE and 92.9% for the 72 implants without TSFE (p = .678). The probability of 10-year survival of all implants in the experimental group decreased to 77.4% for implants placed in residual bone heights of 1-3 mm, compared with 95.7% for implant sites with bone heights of 4-6 mm and 97.6% for bone heights of >6 mm. Conclusions: Transcrestal sinus-floor elevation has no negative effect on the long-term implant survival. Membrane perforation or negligible bone height, however, reduces the probability of 10-year survival.
MeSH term(s)	Dental Implantation, Endosseous ; Dental Implants ; Humans ; Maxilla ; Maxillary Sinus/diagnostic imaging ; Maxillary Sinus/surgery ; Prognosis ; Sinus Floor Augmentation
Chemical Substances	Dental Implants
Language	English
Publishing date	2020-03-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	188647-2
ISSN	1600-051X ; 0303-6979
ISSN (online)	1600-051X
ISSN	0303-6979
DOI	10.1111/jcpe.13278
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Article ; Online: Impact of the COVID-19 pandemic on oral health and psychosocial factors.

Ciardo, Antonio / Simon, Marlinde M / Sonnenschein, Sarah K / Büsch, Christopher / Kim, Ti-Sun

Scientific reports

2022 Volume 12, Issue 1, Page(s) 4477

Abstract: The objective of this study was to investigate oral health-related quality of life (OHRQoL) in times of the COVID-19 pandemic and to examine a possible association to psychosocial factors like psychological stress and symptoms of depression and anxiety ... ...

Abstract	The objective of this study was to investigate oral health-related quality of life (OHRQoL) in times of the COVID-19 pandemic and to examine a possible association to psychosocial factors like psychological stress and symptoms of depression and anxiety disorders. Secondary research questions were whether people changed oral hygiene regimens during the COVID-19 pandemic and to what extent dental symptoms existed and developed compared to pre-pandemic. For this cross-sectional study a survey has been conceptualized to determine OHRQoL, stress, depression and anxiety and their specific confounders in a German cohort. Validated questionnaires as OHIP-G14, PHQ-Stress and PHQ-4 have been implemented. Altogether 1178 participants completed the survey between May and August 2020. The overall OHIP-G14 sum score of 4.8 ± 7.5 indicated good OHRQoL. 21% of the participants (n = 248) reported toothache, 23% (n = 270) mucosal problems, 31% (n = 356) hypersensitivity of the teeth and 27% (n = 305) myofacial pain. The PHQ-Stress score (4.5 ± 3.5) demonstrated a mild severity of stress. Depression and anxiety level has been mild to moderate (PHQ-4 score: 2.4 ± 2.6). 38% of the participants stated subjectively greater emotional burden compared to pre-pandemic. Statistically significant differences exist for OHRQoL, stress, anxiety and depression levels between participants with greater, equal or less emotional burden compared to pre-pandemic. COVID-19 history and aggravated levels of depression, anxiety, and stress seem to associate with lower OHRQoL. Psychosocial consequences during pandemic times and their association to oral health should be further investigated.
MeSH term(s)	COVID-19/epidemiology ; Cross-Sectional Studies ; Humans ; Oral Health ; Pandemics ; Quality of Life/psychology
Language	English
Publishing date	2022-03-16
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-07907-9
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