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Article ; Online: Hollow waveguide-miniaturized quantum cascade laser heterodyne spectro-radiometer.

Robinson, Iain / Butcher, Helen L / Macleod, Neil A / Weidmann, Damien

2021 Volume 29, Issue 2, Page(s) 2299–2308

Abstract: A miniature thermal infrared laser heterodyne spectro-radiometer based on hybrid optical integration is demonstrated. A quantum cascade laser emitting at 953 ... ...

Abstract	A miniature thermal infrared laser heterodyne spectro-radiometer based on hybrid optical integration is demonstrated. A quantum cascade laser emitting at 953 cm
Language	English
Publishing date	2021-01-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491859-6
ISSN	1094-4087 ; 1094-4087
ISSN (online)	1094-4087
ISSN	1094-4087
DOI	10.1364/OE.415371
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Hollow waveguide integrated laser spectrometer for

Robinson, Iain / Butcher, Helen L / Macleod, Neil A / Weidmann, Damien

Optics express

2019 Volume 27, Issue 24, Page(s) 35670–35688

Abstract: Using hollow waveguide hybrid optical integration, a miniaturized mid-infrared laser absorption spectrometer ... ...

Abstract	Using hollow waveguide hybrid optical integration, a miniaturized mid-infrared laser absorption spectrometer for
Language	English
Publishing date	2019-12-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491859-6
ISSN	1094-4087 ; 1094-4087
ISSN (online)	1094-4087
ISSN	1094-4087
DOI	10.1364/OE.27.035670
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Demonstration and characterization of ultrafast laser-inscribed mid-infrared waveguides in chalcogenide glass IG2.

Butcher, Helen L / MacLachlan, David G / Lee, David / Thomson, Robert R / Weidmann, Damien

Optics express

2018 Volume 26, Issue 8, Page(s) 10930–10943

Abstract: The first demonstration and characterization of ultrafast laser-inscribed mid-infrared (mid-IR) waveguides in ... ...

Abstract	The first demonstration and characterization of ultrafast laser-inscribed mid-infrared (mid-IR) waveguides in Ge
Language	English
Publishing date	2018-04-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491859-6
ISSN	1094-4087 ; 1094-4087
ISSN (online)	1094-4087
ISSN	1094-4087
DOI	10.1364/OE.26.010930
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Whose childhood is it?

Butcher, Helen / Eke, Richard / Lee, Mandy

the roles of children, adults, and policy makers

2009

Abstract: The purpose of this book is to promote a thoughtful engagement with key issues and theories that inform our understanding of childhood. Readers will enjoy, and be provoked by, a sophisticated analysis of the role and function of childhood in twenty-first ...

Institution	ebrary, Inc
Author's details	[edited by] Richard Eke, Helen Butcher and Mandy Lee
Abstract	The purpose of this book is to promote a thoughtful engagement with key issues and theories that inform our understanding of childhood. Readers will enjoy, and be provoked by, a sophisticated analysis of the role and function of childhood in twenty-first century Britain, which can be used as a springboard for further enquiry and exploration. Two intertwined themes permeate the text:. . - Children's sense of self and adults' temporal and cultural fabrications of childhood, and the articulation of these with policy and provision for young children. - Young children and represen
Keywords	Child development ; Early childhood education
Language	English
Size	Online-Ressource (viii, 204 p), ill, 24 cm
Publisher	Continuum
Publishing place	London ;New York
Document type	Book ; Online
Note	Includes bibliographical references and index
ISBN	0826499813 ; 1441173579 ; 9780826499813 ; 9781441173577
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Book: On-line information

Walsh, Brendan P / Butcher, Helen / Freund, Alison

a comprehensive business-user's guide

1987

Institution	Institute of Chartered Accountants in England and Wales
Author's details	Brendan P. Walsh; Helen Butcher; Alison Freund. Institute of Chartered Accountants in England and Wales
Language	English
Size	XLI, 327 S, Ill, 26 cm
Publisher	Basil Blackwell
Publishing place	Oxford u.a
Document type	Book
Note	Includes index
ISBN	0631155430 ; 9780631155430
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article: Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission

Rivett, Lucy / Sridhar, Sushmita / Sparkes, Dominic / Routledge, Matthew / Jones, Nick K / Forrest, Sally / Young, Jamie / Pereira-Dias, Joana / Hamilton, William L / Ferris, Mark / Torok, M Estee / Meredith, Luke / Gupta, Ravi / Lyons, Paul A / Toshner, Mark / Warne, Ben / Bartholdson Scott, Josefin / Cormie, Claire / Gill, Harmeet /

eLife (Cambridge)

Abstract: Significant differences exist in the availability of healthcare worker (HCW) SARS-CoV-2 testing between countries, and existing programmes focus on screening symptomatic rather than asymptomatic staff. Over a 3 week period (April 2020), 1032 asymptomatic ...

Abstract	Significant differences exist in the availability of healthcare worker (HCW) SARS-CoV-2 testing between countries, and existing programmes focus on screening symptomatic rather than asymptomatic staff. Over a 3 week period (April 2020), 1032 asymptomatic HCWs were screened for SARS-CoV-2 in a large UK teaching hospital. Symptomatic staff and symptomatic household contacts were additionally tested. Real-time RT-PCR was used to detect viral RNA from a throat+nose self-swab. 3% of HCWs in the asymptomatic screening group tested positive for SARS-CoV-2. 17/30 (57%) were truly asymptomatic/pauci-symptomatic. 12/30 (40%) had experienced symptoms compatible with coronavirus disease 2019 (COVID-19)>7 days prior to testing, most self-isolating, returning well. Clusters of HCW infection were discovered on two independent wards. Viral genome sequencing showed that the majority of HCWs had the dominant lineage Bâ1. Our data demonstrates the utility of comprehensive screening of HCWs with minimal or no symptoms. This approach will be critical for protecting patients and hospital staff.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32392129
Database	COVID19

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Article ; Online: Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission

Kean, Iain / Maes, Mailis / Reynolds, Nicola / Wantoch, Michelle / Caddy, Sarah / Caller, Laura / Feltwell, Theresa / Hall, Grant / Hosmillo, Myra / Houldcroft, Charlotte / Jahun, Aminu / Khokhar, Fahad / Yakovleva, Anna / Butcher, Helen / Caputo, Daniela / Clapham-Riley, Debra / Dolling, Helen / Furlong, Anita / Graves, Barbara / Gresley, Emma Le / Kingston, Nathalie / Papadia, Sofia / Stark, Hannah / Stirrups, Kathleen E / Webster, Jennifer / Calder, Joanna / Harris, Julie / Hewitt, Sarah / Kennet, Jane / Meadows, Anne / Rastall, Rebecca / Brien, Criona O / Price, Jo / Publico, Cherry / Rowlands, Jane / Ruffolo, Valentina / Tordesillas, Hugo / Brookes, Karen / Canna, Laura / Cruz, Isabel / Dempsey, Katie / Elmer, Anne / Escoffery, Naidine / Jones, Heather / Ribeiro, Carla / Saunders, Caroline / Wright, Angela / Nyagumbo, Rutendo / Roberts, Anne / Bucke, Ashlea / Hargreaves, Simone / Johnson, Danielle / Narcorda, Aileen / Read, Debbie / Sparke, Christian / Warboys, Lucy / Lagadu, Kirsty / Mactavous, Lenette / Gould, Tim / Raine, Tim / Mather, Claire / Ramenatte, Nicola / Vallier, Anne-Laure / Kasanicki, Mary / Eames, Penelope-Jane / McNicholas, Chris / Thake, Lisa / Bartholomew, Neil / Brown, Nick / Parmar, Surendra / Zhang, Hongyi / Bowring, Ailsa / Martell, Geraldine / Quinnell, Natalie / Wright, Jo / Murphy, Helen / Dunmore, Benjamin J / Legchenko, Ekaterina / Gräf, Stefan / Huang, Christopher / Hodgson, Josh / Hunter, Kelvin / Martin, Jennifer / Mescia, Federica / O'Donnell, Ciara / Pointon, Linda / Shih, Joy / Sutcliffe, Rachel / Tilly, Tobias / Tong, Zhen / Treacy, Carmen / Wood, Jennifer / Bergamaschi, Laura / Betancourt, Ariana / Bowyer, Georgie / De Sa, Aloka / Epping, Maddie / Hinch, Andrew / Huhn, Oisin / Jarvis, Isobel / Lewis, Daniel / Marsden, Joe / McCallum, Simon / Nice, Francescsa / Curran, Martin D / Fuller, Stewart / Chaudhry, Afzal / Shaw, Ashley / Samworth, Richard J / Bradley, John R / Dougan, Gordon / Smith, Kenneth GC / Lehner, Paul J / Matheson, Nicholas J / Wright, Giles / Goodfellow, Ian G / Baker, Stephen / Weekes, Michael P

eLife

2020 Volume 9

Abstract	Significant differences exist in the availability of healthcare worker (HCW) SARS-CoV-2 testing between countries, and existing programmes focus on screening symptomatic rather than asymptomatic staff. Over a 3 week period (April 2020), 1032 asymptomatic HCWs were screened for SARS-CoV-2 in a large UK teaching hospital. Symptomatic staff and symptomatic household contacts were additionally tested. Real-time RT-PCR was used to detect viral RNA from a throat+nose self-swab. 3% of HCWs in the asymptomatic screening group tested positive for SARS-CoV-2. 17/30 (57%) were truly asymptomatic/pauci-symptomatic. 12/30 (40%) had experienced symptoms compatible with coronavirus disease 2019 (COVID-19)>7 days prior to testing, most self-isolating, returning well. Clusters of HCW infection were discovered on two independent wards. Viral genome sequencing showed that the majority of HCWs had the dominant lineage B∙1. Our data demonstrates the utility of comprehensive screening of HCWs with minimal or no symptoms. This approach will be critical for protecting patients and hospital staff.
Keywords	General Biochemistry, Genetics and Molecular Biology ; General Immunology and Microbiology ; General Neuroscience ; General Medicine ; covid19
Language	English
Publisher	eLife Sciences Publications, Ltd
Publishing country	uk
Document type	Article ; Online
ZDB-ID	2687154-3
ISSN	2050-084X
ISSN	2050-084X
DOI	10.7554/elife.58728
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission

Rivett, Lucy / Sridhar, Sushmita / Sparkes, Dominic / Routledge, Matthew / Jones, Nick K / Forrest, Sally / Young, Jamie / Pereira-Dias, Joana / Hamilton, William L / Ferris, Mark / Torok, M Estee / Meredith, Luke / The CITIID-NIHR COVID-19 BioResource Collaboration / Curran, Martin D / Fuller, Stewart / Chaudhry, Afzal / Shaw, Ashley / Samworth, Richard J / Bradley, John R /

Dougan, Gordon / Smith, Kenneth GC / Lehner, Paul J / Matheson, Nicholas J / Wright, Giles / Goodfellow, Ian G / Baker, Stephen / Weekes, Michael P / Gupta, Ravi / Lyons, Paul A / Toshner, Mark / Warne, Ben / Bartholdson Scott, Josefin / Cormie, Claire / Gill, Harmeet / Kean, Iain / Maes, Mailis / Reynolds, Nicola / Wantoch, Michelle / Caddy, Sarah / Caller, Laura / Feltwell, Theresa / Hall, Grant / Hosmillo, Myra / Houldcroft, Charlotte / Jahun, Aminu / Khokhar, Fahad / Yakovleva, Anna / Butcher, Helen / Caputo, Daniela / Clapham-Riley, Debra / Dolling, Helen / Furlong, Anita / Graves, Barbara / Gresley, Emma Le / Kingston, Nathalie / Papadia, Sofia / Stark, Hannah / Stirrups, Kathleen E / Webster, Jennifer / Calder, Joanna / Harris, Julie / Hewitt, Sarah / Kennet, Jane / Meadows, Anne / Rastall, Rebecca / Brien, Criona O / Price, Jo / Publico, Cherry / Rowlands, Jane / Ruffolo, Valentina / Tordesillas, Hugo / Brookes, Karen / Canna, Laura / Cruz, Isabel / Dempsey, Katie / Elmer, Anne / Escoffery, Naidine / Jones, Heather / Ribeiro, Carla / Saunders, Caroline / Wright, Angela / Nyagumbo, Rutendo / Roberts, Anne / Bucke, Ashlea / Hargreaves, Simone / Johnson, Danielle / Narcorda, Aileen / Read, Debbie / Sparke, Christian / Warboys, Lucy / Lagadu, Kirsty / Mactavous, Lenette / Gould, Tim / Raine, Tim / Mather, Claire / Ramenatte, Nicola / Vallier, Anne-Laure / Kasanicki, Mary / Eames, Penelope-Jane / McNicholas, Chris / Thake, Lisa / Bartholomew, Neil / Brown, Nick / Parmar, Surendra / Zhang, Hongyi / Bowring, Ailsa / Martell, Geraldine / Quinnell, Natalie / Wright, Jo / Murphy, Helen / Dunmore, Benjamin J / Legchenko, Ekaterina / Gräf, Stefan / Huang, Christopher / Hodgson, Josh / Hunter, Kelvin / Martin, Jennifer / Mescia, Federica / O'Donnell, Ciara / Pointon, Linda / Shih, Joy / Sutcliffe, Rachel / Tilly, Tobias / Tong, Zhen / Treacy, Carmen / Wood, Jennifer / Bergamaschi, Laura / Betancourt, Ariana / Bowyer, Georgie / De Sa, Aloka / Epping, Maddie / Hinch, Andrew / Huhn, Oisin / Jarvis, Isobel / Lewis, Daniel / Marsden, Joe / McCallum, Simon / Nice, Francescsa

2020

Abstract: Funder: Addenbrooke's Charitable Trust, Cambridge University Hospitals; FundRef: http://dx.doi.org/10.13039/501100002927 ... Significant differences exist in the availability of healthcare worker (HCW) SARS-CoV-2 testing between countries, and existing ... ...

Abstract	Funder: Addenbrooke's Charitable Trust, Cambridge University Hospitals; FundRef: http://dx.doi.org/10.13039/501100002927 Significant differences exist in the availability of healthcare worker (HCW) SARS-CoV-2 testing between countries, and existing programmes focus on screening symptomatic rather than asymptomatic staff. Over a 3 week period (April 2020), 1032 asymptomatic HCWs were screened for SARS-CoV-2 in a large UK teaching hospital. Symptomatic staff and symptomatic household contacts were additionally tested. Real-time RT-PCR was used to detect viral RNA from a throat+nose self-swab. 3% of HCWs in the asymptomatic screening group tested positive for SARS-CoV-2. 17/30 (57%) were truly asymptomatic/pauci-symptomatic. 12/30 (40%) had experienced symptoms compatible with coronavirus disease 2019 (COVID-19)>7 days prior to testing, most self-isolating, returning well. Clusters of HCW infection were discovered on two independent wards. Viral genome sequencing showed that the majority of HCWs had the dominant lineage B∙1. Our data demonstrates the utility of comprehensive screening of HCWs with minimal or no symptoms. This approach will be critical for protecting patients and hospital staff.
Keywords	Research Article ; Epidemiology and Global Health ; Human Biology and Medicine ; COVID-19 ; SARS-CoV-2 ; infectious disease ; virology ; occupational health ; emerging pathogens ; Human ; Virus ; covid19
Language	English
Publishing date	2020-06-25T05:08:08Z
Publisher	eLife Sciences Publications, Ltd
Publishing country	uk
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: Author response

Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission

2020

Keywords	covid19
Publisher	eLife Sciences Publications, Ltd
Publishing country	uk
Document type	Book ; Online
DOI	10.7554/elife.58728.sa2
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Combined point of care nucleic acid and antibody testing for SARS-CoV-2 following emergence of D614G Spike Variant

Mlcochova, Petra / Collier, Dami / Ritchie, Allyson / Assennato, Sonny M. / Hosmillo, Myra / Goel, Neha / Meng, Bo / Chatterjee, Krishna / Mendoza, Vivien / Temperton, Nigel J. / Kiss, Leo / James, Leo C. / Ciazynska, Katarzyna A. / Xiong, Xiaoli / Briggs, John AG. / Nathan, James A. / Mescia, Federica / Bergamaschi, Laura / Zhang, Hongyi /

Barmpounakis, Petros / Demeris, Nikos / Skells, Richard / Lyons, Paul A. / Bradley, John / Baker, Steven / Allain, Jean Pierre / Smith, Kenneth GC. / Bousfield, Rachel / Wilson, Michael / Sparkes, Dominic / Amoroso, Glenn / Gkrania-Klotsas, Effrosyni / Hardwick, Susie / Boyle, Adrian / Goodfellow, Ian / Gupta, Ravindra K. / Baker, Stephen / Dougan, Gordon / Gupta, Ravi / Lehner, Paul J. / Lyons, Paul / Matheson, Nicholas J. / Smith, Kenneth G.C. / Toshner, Mark / Weekes, Michael P. / Brown, Nick / Curran, Martin / Palmar, Surendra / Enoch, David / Chapman, Daniel / Shaw, Ashley / Jose, Sherly / Bermperi, Areti / Zerrudo, Julie Ann / Kourampa, Evgenia / Watson, Laura / Worsley, Jieniean / Saunders, Caroline / de Jesus, Ranalie / Domingo, Jason / Pasquale, Ciro / Vergese, Bensi / Vargas, Phoebe / Fabiculana, Marivic / Perales, Marlyn / Mynott, Lee / Blake, Elizabeth / Bates, Amy / Vallier, Anne-Laure / Williams, Alexandra / Phillips, David / Chiu, Edmund / Overhill, Alex / Ramenatte, Nicola / Sipple, Jamal / Frost, Steven / Knock, Helena / Hardy, Richard / Foster, Emily / Davidson, Fiona / Rundell, Viona / Bundi, Purity / Abeseabe, Richmond / Clark, Sarah / Vicente, Isabel / Elmer, Anne / Ribeiro, Carla / Kourampa, Jenny / Kennet, Jane / Rowlands, Jane / Meadows, Anne / O’Brien, Criona / Rastall, Rebecca / Crucusio, Cherry / Hewitt, Sarah / Price, Jane / Calder, Jo / Canna, Laura / Bucke, Ashlea / Tordesillas, Hugo / Harris, Julie / Ruffolo, Valentina / Graves, Barbara / Butcher, Helen / Caputo, Daniela / Le Gresley, Emma / Dunmore, Benjamin J. / Martin, Jennifer / Legchenko, Ekaterina / Treacy, Carmen / Huang, Christopher / Wood, Jennifer / Sutcliffe, Rachel / Hodgson, Josh / Shih, Joy / Graf, Stefan / Tong, Zhen / Tilly, Tobias / O’Donnell, Ciara / Hunter, Kelvin / Pointon, Linda / Pond, Nicole / Wylot, Marta / Jones, Emma / Fawke, Stuart / Bullman, Ben / Turner, Lori / Jarvis, Isobel / Omarjee, Ommar / De Sa, Aloka / Marsden, Joe / Betancourt, Ariana / Perera, Marianne / Epping, Maddie / Richoz, Nathan / Bower, Georgie / Sharma, Rahul / Nice, Francesca / Huhn, Oisin / Yarkoni, Natalia Savoinykh / Romashova, Nika / Lewis, Daniel / Hinch, Andrew / Cossetti, Chiara / Strezlecki, Mateusz / Grenfell, Richard / Stark, Hannah / Walker, Neil / Stirrups, Kathy / Ovington, Nigel / Dewhust, Eleanor / Li, Emily / Papadia, Sofia

2020

Abstract: Rapid COVID-19 diagnosis in hospital is essential, though complicated by 30-50% of nose/throat swabs being negative by SARS-CoV-2 nucleic acid amplification testing (NAAT). Furthermore, the D614G spike mutant now dominates the pandemic and it is unclear ... ...

Abstract	Rapid COVID-19 diagnosis in hospital is essential, though complicated by 30-50% of nose/throat swabs being negative by SARS-CoV-2 nucleic acid amplification testing (NAAT). Furthermore, the D614G spike mutant now dominates the pandemic and it is unclear how serological tests designed to detect anti-Spike antibodies perform against this variant. We assess the diagnostic accuracy of combined rapid antibody point of care (POC) and nucleic acid assays for suspected COVID-19 disease due to either wild type or the D614G spike mutant SARS-CoV-2. The overall detection rate for COVID-19 is 79.2% (95CI 57.8-92.9%) by rapid NAAT alone. Combined point of care antibody test and rapid NAAT is not impacted by D614G and results in very high sensitivity for COVID-19 diagnosis with very high specificity.
Keywords	QR355 Virology ; covid19
Language	English
Publishing date	2020-09-01
Publisher	Elsevier
Publishing country	uk
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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