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  1. Article ; Online: Survival following lung volume reduction procedures: results from the UK Lung Volume Reduction (UKLVR) registry.

    Buttery, S C / Lewis, A / Alzetani, A / Bolton, C E / Curtis, K J / Dodd, J W / Habib, A M / Hussain, A / Havelock, T / Jordan, S / Kallis, C / Kemp, S V / Kirk, A / Lawson, R A / Mahadeva, R / Munavvar, M / Naidu, B / Rathinam, S / Shackcloth, M /
    Shah, P L / Tenconi, S / Hopkinson, N S

    BMJ open respiratory research

    2024  Volume 11, Issue 1

    Abstract: Introduction: Lung volume reduction surgery (LVRS) and endobronchial valve (EBV) placement can produce substantial benefits in appropriately selected people with emphysema. The UK Lung Volume Reduction (UKLVR) registry is a national multicentre ... ...

    Abstract Introduction: Lung volume reduction surgery (LVRS) and endobronchial valve (EBV) placement can produce substantial benefits in appropriately selected people with emphysema. The UK Lung Volume Reduction (UKLVR) registry is a national multicentre observational study set up to support quality standards and assess outcomes from LVR procedures at specialist centres across the UK.
    Methods: Data were analysed for all patients undergoing an LVR procedure (LVRS/EBV) who were recruited into the study at participating centres between January 2017 and June 2022, including; disease severity and risk assessment, compliance with guidelines for selection, procedural complications and survival to February 2023.
    Results: Data on 541 patients from 14 participating centres were analysed. Baseline disease severity was similar in patients who had surgery n=244 (44.9%), or EBV placement n=219 (40.9%), for example, forced expiratory volume in 1 s (FEV
    MeSH term(s) Humans ; Male ; Emphysema ; Lung/surgery ; Pneumonectomy/adverse effects ; Pneumonectomy/methods ; Pulmonary Emphysema/surgery ; Registries ; United Kingdom ; Female
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2736454-9
    ISSN 2052-4439 ; 2052-4439
    ISSN (online) 2052-4439
    ISSN 2052-4439
    DOI 10.1136/bmjresp-2023-002092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Physical activity is increased by a 12-week semiautomated telecoaching programme in patients with COPD: a multicentre randomised controlled trial.

    Demeyer, H / Louvaris, Z / Frei, A / Rabinovich, R A / de Jong, C / Gimeno-Santos, E / Loeckx, M / Buttery, S C / Rubio, N / Van der Molen, T / Hopkinson, N S / Vogiatzis, I / Puhan, M A / Garcia-Aymerich, J / Polkey, M I / Troosters, T

    Thorax

    2017  Volume 72, Issue 5, Page(s) 415–423

    Abstract: Rationale: Reduced physical activity (PA) in patients with COPD is associated with a poor prognosis. Increasing PA is a key therapeutic target, but thus far few strategies have been found effective in this patient group.: Objectives: To investigate ... ...

    Abstract Rationale: Reduced physical activity (PA) in patients with COPD is associated with a poor prognosis. Increasing PA is a key therapeutic target, but thus far few strategies have been found effective in this patient group.
    Objectives: To investigate the effectiveness of a 12-week semiautomated telecoaching intervention on PA in patients with COPD in a multicentre European randomised controlled trial.
    Methods: 343 patients from six centres, encompassing a wide spectrum of disease severity, were randomly allocated to either a usual care group (UCG) or a telecoaching intervention group (IG) between June and December 2014. This 12-week intervention included an exercise booklet and a step counter providing feedback both directly and via a dedicated smartphone application. The latter provided an individualised daily activity goal (steps) revised weekly and text messages as well as allowing occasional telephone contacts with investigators. PA was measured using accelerometry during 1 week preceding randomisation and during week 12. Secondary outcomes included exercise capacity and health status. Analyses were based on modified intention to treat.
    Main results: Both groups were comparable at baseline in terms of factors influencing PA. At 12 weeks, the intervention yielded a between-group difference of mean, 95% CI (lower limit - upper limit; ll-ul) +1469, 95% CI (971 to 1965) steps/day and +10.4, 95% CI (6.1 to 14.7) min/day moderate PA; favouring the IG (all p≤0.001). The change in 6-min walk distance was significantly different (13.4, 95% CI (3.40 to 23.5) m, p<0.01), favouring the IG. In IG patients, an improvement could be observed in the functional state domain of the clinical COPD questionnaire (p=0.03) compared with UCG. Other health status outcomes did not differ.
    Conclusions: The amount and intensity of PA can be significantly increased in patients with COPD using a 12-week semiautomated telecoaching intervention including a step counter and an application installed on a smartphone.
    Trial registration number: NCT02158065.
    MeSH term(s) Aged ; Exercise/physiology ; Exercise Therapy/methods ; Female ; Greece ; Humans ; Male ; Middle Aged ; Netherlands ; Prognosis ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Pulmonary Disease, Chronic Obstructive/rehabilitation ; Spirometry ; Switzerland ; Telemedicine ; Treatment Outcome ; United Kingdom
    Language English
    Publishing date 2017-01-30
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 204353-1
    ISSN 1468-3296 ; 0040-6376
    ISSN (online) 1468-3296
    ISSN 0040-6376
    DOI 10.1136/thoraxjnl-2016-209026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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