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  1. Article ; Online: Getting better at quantifying the toxicity of glucocorticoids.

    Buttgereit, Frank

    The Lancet. Rheumatology

    2023  Volume 5, Issue 7, Page(s) e368–e370

    MeSH term(s) Glucocorticoids/toxicity
    Chemical Substances Glucocorticoids
    Language English
    Publishing date 2023-08-21
    Publishing country England
    Document type Journal Article
    ISSN 2665-9913
    ISSN (online) 2665-9913
    DOI 10.1016/S2665-9913(23)00159-5
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  2. Book ; Conference proceedings: Research Symposium Rheumatology and Dermatology

    Buttgereit, Frank

    Berlin, September 16 - 17, 2011 ; abstracts

    (Zeitschrift für Rheumatologie ; 71, Suppl. 1)

    2012  

    Event/congress Research Symposium Rheumatology and Dermatology (2011, Berlin)
    Author's details guest ed. suppl.: Frank Buttgereit
    Series title Zeitschrift für Rheumatologie ; 71, Suppl. 1
    Collection
    Language English
    Size 16 S. : Ill., graph. Darst.
    Publisher Springer-Medizin
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Conference proceedings
    HBZ-ID HT017166168
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Glucocorticoids: surprising new findings on their mechanisms of actions.

    Buttgereit, Frank

    Annals of the rheumatic diseases

    2020  Volume 80, Issue 2, Page(s) 137–139

    MeSH term(s) Animals ; Glucocorticoids/immunology ; Glucocorticoids/pharmacology ; Humans ; Immune System Phenomena/drug effects ; Rheumatic Diseases/drug therapy ; Rheumatic Diseases/immunology
    Chemical Substances Glucocorticoids
    Language English
    Publishing date 2020-11-08
    Publishing country England
    Document type Editorial
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/annrheumdis-2020-218798
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  4. Article ; Online: Views on glucocorticoid therapy in rheumatology: the age of convergence.

    Buttgereit, Frank

    Nature reviews. Rheumatology

    2020  Volume 16, Issue 4, Page(s) 239–246

    Abstract: After decades of sometimes fierce debate about the advantages and disadvantages of glucocorticoids, an age of convergence has been reached. Current recommendations for the management of diseases such as rheumatoid arthritis (RA), polymyalgia rheumatica ... ...

    Abstract After decades of sometimes fierce debate about the advantages and disadvantages of glucocorticoids, an age of convergence has been reached. Current recommendations for the management of diseases such as rheumatoid arthritis (RA), polymyalgia rheumatica and large vessel vasculitis reflect the current consensus that as much glucocorticoid as necessary, but as little as possible, should be used. Over the past few years, a range of glucocorticoid-sparing strategies have been developed, as have tools to improve the management of this therapy. A comprehensive view of glucocorticoid-induced osteoporosis has also emerged that recognizes that bone fragility is not solely determined by the dose and duration of glucocorticoid treatment. Nevertheless, open questions remain around whether long-term use of very low doses of glucocorticoids is a realistic option for patients with RA and whether the search for innovative glucocorticoids or glucocorticoid receptor ligands with improved benefit-to-risk ratios will ultimately be successful.
    MeSH term(s) Antirheumatic Agents/therapeutic use ; Glucocorticoids/therapeutic use ; Humans ; Rheumatic Diseases/drug therapy ; Rheumatology ; Treatment Outcome
    Chemical Substances Antirheumatic Agents ; Glucocorticoids
    Language English
    Publishing date 2020-02-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2491532-4
    ISSN 1759-4804 ; 1759-4790
    ISSN (online) 1759-4804
    ISSN 1759-4790
    DOI 10.1038/s41584-020-0370-z
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  5. Article ; Online: Can we shift the benefit-risk ratio of glucocorticoids?

    Buttgereit, Frank

    The Lancet. Rheumatology

    2019  Volume 2, Issue 1, Page(s) e5–e6

    Language English
    Publishing date 2019-12-09
    Publishing country England
    Document type Journal Article
    ISSN 2665-9913
    ISSN (online) 2665-9913
    DOI 10.1016/S2665-9913(19)30138-9
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  6. Article ; Online: Controversies in rheumatology: maintenance therapy with low-dose glucocorticoids in rheumatoid arthritis.

    Buttgereit, Frank / Kvien, Tore K

    Rheumatology (Oxford, England)

    2022  Volume 62, Issue 1, Page(s) 35–41

    Abstract: Since the beginning of the use of glucocorticoids in clinical medicine, the risk-benefit ratio of these still very important drugs has been debated. There is no doubt that they produce many desirable therapeutic effects quickly and reliably. However, ... ...

    Abstract Since the beginning of the use of glucocorticoids in clinical medicine, the risk-benefit ratio of these still very important drugs has been debated. There is no doubt that they produce many desirable therapeutic effects quickly and reliably. However, their potential to cause adverse effects, especially with prolonged use in high doses, limits their applicability. We discuss the arguments against and in favour of maintenance therapy with low-dose glucocorticoids in patients with RA, and present recent studies, assessments and conclusions on this question.
    MeSH term(s) Humans ; Glucocorticoids/adverse effects ; Rheumatology ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/chemically induced ; Risk Assessment ; Drug-Related Side Effects and Adverse Reactions ; Antirheumatic Agents/adverse effects
    Chemical Substances Glucocorticoids ; Antirheumatic Agents
    Language English
    Publishing date 2022-06-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/keac355
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    Zs.MO 497: Show issues

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  7. Article ; Online: A new perspective is needed for positive selection of germinal center B cells with higher-affinity B cell receptors.

    Gaber, Timo / Buttgereit, Frank

    Cellular & molecular immunology

    2022  Volume 19, Issue 2, Page(s) 145–146

    MeSH term(s) B-Lymphocytes ; Germinal Center ; Receptors, Antigen, B-Cell
    Chemical Substances Receptors, Antigen, B-Cell
    Language English
    Publishing date 2022-01-07
    Publishing country China
    Document type Journal Article ; Comment
    ZDB-ID 2435097-7
    ISSN 2042-0226 ; 1672-7681
    ISSN (online) 2042-0226
    ISSN 1672-7681
    DOI 10.1038/s41423-021-00823-4
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  8. Article ; Online: The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis.

    Palmowski, Andriko / Boers, Maarten / Kirwan, John / Christensen, Robin / Buttgereit, Frank

    Annals of internal medicine

    2024  Volume 177, Issue 4, Page(s) 546–547

    MeSH term(s) Humans ; Glucocorticoids/therapeutic use ; Blood Pressure ; Arthritis, Rheumatoid/drug therapy ; Antirheumatic Agents/therapeutic use ; Vital Signs
    Chemical Substances Glucocorticoids ; Antirheumatic Agents
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/L24-0006
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  9. Article ; Online: Tocilizumab in Giant Cell Arteritis: Better Understanding the Benefits.

    Buttgereit, Frank / Palmowski, Andriko / Esen, Idil / Brouwer, Elisabeth

    Arthritis & rheumatology (Hoboken, N.J.)

    2023  Volume 75, Issue 4, Page(s) 489–492

    MeSH term(s) Humans ; Giant Cell Arteritis/drug therapy ; Antibodies, Monoclonal, Humanized/therapeutic use ; Glucocorticoids
    Chemical Substances tocilizumab (I031V2H011) ; Antibodies, Monoclonal, Humanized ; Glucocorticoids
    Language English
    Publishing date 2023-01-24
    Publishing country United States
    Document type Editorial
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.42414
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  10. Article ; Online: Trabecular Bone Score in der Rheumatologie : Gibt es einen Nutzen im Vergleich zur alleinigen Osteodensitometrie?

    Boyadzhieva, Zhivana / Palmowski, Andriko / Buttgereit, Frank / Hoff, Paula

    Zeitschrift fur Rheumatologie

    2023  Volume 82, Issue 8, Page(s) 672–677

    Abstract: Patients with inflammatory rheumatic diseases have an increased risk of fractures due to the inflammatory potential of the disease and also because of the treatment with glucocorticoids that is often necessary. According to the current guidelines of the ... ...

    Title translation Trabecular bone score in rheumatology : Are there benefits in comparison to bone densitometry alone?
    Abstract Patients with inflammatory rheumatic diseases have an increased risk of fractures due to the inflammatory potential of the disease and also because of the treatment with glucocorticoids that is often necessary. According to the current guidelines of the Governing Body on Osteology (DVO), the fracture risk can be assessed using dual energy X‑ray absorptiometry and can also be supplemented by measuring the trabecular bone score (TBS). The assessment of the TBS offers additional advantages, for example in glucocorticoid-induced osteoporosis and in patients with osteoproliferative changes of the spine (spondylarthritis) and thus optimizes the fracture risk assessment in the rheumatological patient population.
    Language German
    Publishing date 2023-08-30
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 124985-x
    ISSN 1435-1250 ; 0340-1855 ; 0301-6382
    ISSN (online) 1435-1250
    ISSN 0340-1855 ; 0301-6382
    DOI 10.1007/s00393-023-01407-5
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