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Article ; Online: Assessing Gender Differences on the Impact of COVID-19 on the Medical and Social Needs of Dementia Caregivers.

Lloyd, Shawnta L / Caban-Holt, Allison / Starks, Takiyah D / Clark, Jarrel C / Byrd, Goldie S

2023 Volume 67, Issue 2, Page(s) 207–222

Abstract: Our analyses aimed to assess health status and critical needs of caregivers of persons with dementia (PWD) during the COVID-19 pandemic by gender. Between March 2021 and August 2021, respondents ( ...

Abstract	Our analyses aimed to assess health status and critical needs of caregivers of persons with dementia (PWD) during the COVID-19 pandemic by gender. Between March 2021 and August 2021, respondents (
MeSH term(s)	Male ; Humans ; Female ; Caregivers/psychology ; Dementia/complications ; Dementia/epidemiology ; COVID-19 Testing ; Sex Factors ; Pandemics ; COVID-19/epidemiology
Language	English
Publishing date	2023-08-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	779365-0
ISSN	1540-4048 ; 0163-4372
ISSN (online)	1540-4048
ISSN	0163-4372
DOI	10.1080/01634372.2023.2244556
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Article ; Online: Building a Community Partnership for the Development of Health Ministries Within the African American Community: The Triad Pastors Network.

Gwathmey, TanYa M / Williams, K Lamonte / Caban-Holt, Allison / Starks, Takiyah D / Foy, Capri G / Mathews, Allison / Byrd, Goldie S

Journal of community health

2024 Volume 49, Issue 3, Page(s) 559–567

Abstract: African Americans continue to have worse health outcomes despite attempts to reduce health disparities. This is due, in part, to inadequate access to healthcare, but also to the health care and medical mistrust experienced by communities of color. ... ...

Abstract	African Americans continue to have worse health outcomes despite attempts to reduce health disparities. This is due, in part, to inadequate access to healthcare, but also to the health care and medical mistrust experienced by communities of color. Churches and worship centers have historically served as cultural centers of trusted resources for educational, financial, and health information within African American communities and a growing number of collaborations have developed between academic institutions and community/faith entities. Herein, we describe the infrastructure of a true and sustainable partnership developed with > 100 prominent faith leaders within the Piedmont Triad region of North Carolina for the purpose of developing or expanding existing health ministries within houses of worship, to improve health literacy and overall health long-term. The Triad Pastors Network is an asset-based partnership between the Maya Angelou Center for Health Equity at Wake Forest University School of Medicine and faith leaders in the Piedmont Triad region of North Carolina that was created under the guiding principles of community engagement to improve health equity and decrease health disparities experienced by African American communities. A partnership in which co-equality and shared governance are the core of the framework provides an effective means of achieving health-related goals in a productive and efficient manner. Faith-based partnerships are reliable approaches for improving the health literacy needed to address health disparities and inequities in communities of color.
MeSH term(s)	Humans ; Black or African American ; Clergy ; Health Promotion ; North Carolina ; Trust ; Health Literacy ; Health Inequities
Language	English
Publishing date	2024-01-24
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	426631-6
ISSN	1573-3610 ; 0094-5145
ISSN (online)	1573-3610
ISSN	0094-5145
DOI	10.1007/s10900-023-01315-4
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Article ; Online: The Black Men's Health Forum: Improving Health Knowledge and Willingness to Participate in Research.

Lloyd, Shawnta L / Williams, Kelvin L / Pastors Network, Triad / Caban-Holt, Allison / Craft, Suzanne / D Baker, Laura / Byrd, Goldie S

Health education & behavior : the official publication of the Society for Public Health Education

2023 Volume 51, Issue 1, Page(s) 104–112

Abstract: The Black Men's Health Forum, a 6-week online health education intervention for African American men and accountability partners of African American men, was conducted to increase awareness of health issues that disproportionately affect African American ...

Abstract	The Black Men's Health Forum, a 6-week online health education intervention for African American men and accountability partners of African American men, was conducted to increase awareness of health issues that disproportionately affect African American men. In this article, we describe the intervention and report on the immediate benefits of the intervention, including changes in health knowledge and perception of research participation. Participants completed a pre-evaluation prior to participating in the forum and a post-evaluation after each session to capture data on sociodemographic information, medical history, health knowledge, and health behaviors. A total of 60 participants (30 African American men and 30 accountability partners) completed the forum. African American men had a mean age of 61.1 years while accountability partners had a mean age of 57.6 years. Overall health knowledge increased by 6.9 points for African American men and 2.8 points for accountability partners. Before the forum began, nine African American men reported ever participating in a research study. The proportion of African American men who reported that they would definitely participate in research in the next 12 months after participating in the forum increased by 40%. Through culturally tailored programming, the Black Men's Health Forum increased access to health information as well as African American male medical professionals and health researchers for African American men in the community. Exposure to health information resulted in significant increases in health knowledge and willingness to participate in health research among African American men.
MeSH term(s)	Humans ; Male ; Middle Aged ; Black or African American ; Health Behavior ; Health Education ; Men's Health ; Health Knowledge, Attitudes, Practice ; Patient Participation
Language	English
Publishing date	2023-10-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	1362906-2
ISSN	1552-6127 ; 1090-1981
ISSN (online)	1552-6127
ISSN	1090-1981
DOI	10.1177/10901981231206074
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Article ; Online: Attitudes and Perceptions about Brain Donation Among African Americans: Implications for Recruitment into Alzheimer's Disease Research.

Caban-Holt, Allison / Cuccaro, Michael L / Lloyd, Shawnta L / Starks, Takiyah D / Adams, Larry D / Ford, Tayla / Haines, Jonathan L / Beecham, Gary / Reitz, Christiane / Vance, Jeffery M / Pericak-Vance, Margaret A / Byrd, Goldie S

Journal of Alzheimer's disease : JAD

2024 Volume 97, Issue 4, Page(s) 1621–1627

Abstract: The objective of this study was to investigate attitudes toward brain donation and perceptions of medical research that influence brain donation among African Americans. Cross-sectional surveys were administered to African American community members (n = ...

Abstract	The objective of this study was to investigate attitudes toward brain donation and perceptions of medical research that influence brain donation among African Americans. Cross-sectional surveys were administered to African American community members (n = 227). Findings indicate that only 27% of respondents were willing to donate their brain. As medical mistrust was not found to be a significant barrier to research participation, there may be opportunity to increase brain donation by providing information about Alzheimer's disease and brain donation to potential donors and their families so that informed decisions about participating in research can be made.
MeSH term(s)	Humans ; Alzheimer Disease ; Attitude ; Black or African American/psychology ; Brain ; Cross-Sectional Studies ; Health Knowledge, Attitudes, Practice ; Surveys and Questionnaires ; Tissue and Organ Procurement ; Patient Selection ; Biomedical Research
Language	English
Publishing date	2024-02-02
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1440127-7
ISSN	1875-8908 ; 1387-2877
ISSN (online)	1875-8908
ISSN	1387-2877
DOI	10.3233/JAD-230461
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Article ; Online: Generation of an induced pluripotent stem cell line (UMi043-A) from an African American patient with Alzheimer's disease carrying an ABCA7 deletion (p.Arg578Alafs).

Cukier, Holly N / Simon, Shaina A / Tang, Eugene / Golightly, Charles G / Laverde-Paz, Mayra Juliana / Adams, Larry Deon / Starks, Takiyah D / Vance, Jeffery M / Cuccaro, Michael L / Haines, Jonathan L / Byrd, Goldie S / Pericak-Vance, Margaret A / Dykxhoorn, Derek M

Stem cell research

2024 Volume 76, Page(s) 103364

Abstract: The ATP-binding cassette, subfamily A (ABC1), member 7 (ABCA7) gene is associated with Alzheimer's disease (AD) risk in populations of African, Asian, and European ... ...

Abstract	The ATP-binding cassette, subfamily A (ABC1), member 7 (ABCA7) gene is associated with Alzheimer's disease (AD) risk in populations of African, Asian, and European ancestry
MeSH term(s)	Humans ; Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; ATP-Binding Cassette Transporters/genetics ; Black or African American/genetics ; Induced Pluripotent Stem Cells/cytology ; Mutation ; Cell Line
Chemical Substances	ABCA7 protein, human ; ATP-Binding Cassette Transporters
Language	English
Publishing date	2024-02-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2393143-7
ISSN	1876-7753 ; 1873-5061
ISSN (online)	1876-7753
ISSN	1873-5061
DOI	10.1016/j.scr.2024.103364
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Article ; Online: Leveraging African American family connectors for Alzheimer's disease genomic studies.

Byfield, Grace / Starks, Takiyah D / Luther, Ronqeiya / Edwards, Christopher L / Lloyd, Shawnta L / Caban-Holt, Allison / Adams, Larry Deon / Vance, Jeffery M / Cuccaro, Michael / Haines, Jonathan L / Reitz, Christiane / Pericak-Vance, Margaret A / Byrd, Goldie S

Alzheimer's & dementia : the journal of the Alzheimer's Association

2023 Volume 19, Issue 12, Page(s) 5437–5446

Abstract: Introduction: The underrepresentation of African Americans (AAs) in Alzheimer's disease (AD) research may limit potential benefits from translational applications. This article describes an approach to recruit AA families into an AD genomic study and ... ...

Abstract	Introduction: The underrepresentation of African Americans (AAs) in Alzheimer's disease (AD) research may limit potential benefits from translational applications. This article describes an approach to recruit AA families into an AD genomic study and characteristics of seeds (family connectors) used to overcome recruitment barriers of AA families into AD research. Methods: A four-step outreach and snowball sampling approach relying on family connectors was used to recruit AA families. Descriptive statistics of a profile survey were gathered to understand the demographic and health characteristics of family connectors. Results: Twenty-five AA families (117 participants) were enrolled in the study via family connectors. Most family connectors self-identified as female (88%), were 60 years of age or older (76%), and attained post-secondary education (77%). Discussion: Community-engaged strategies were essential to recruit AA families. Relationships between study coordinators and family connectors build trust early in the research process among AA families. Highlights: Community events were most effective for recruiting African American families. Family connectors were primarily female, in good health, and highly educated. Systematic efforts by researchers are necessary to "sell" a study to participants.
MeSH term(s)	Female ; Humans ; Alzheimer Disease/genetics ; Black or African American ; Genomics ; Male ; Middle Aged
Language	English
Publishing date	2023-05-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	2211627-8
ISSN	1552-5279 ; 1552-5260
ISSN (online)	1552-5279
ISSN	1552-5260
DOI	10.1002/alz.13106
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Zs.A 6316: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Assessing the Role of Trust in Public Health Agencies and COVID-19 Vaccination Status Among a Community Sample of African Americans in North Carolina.

Lloyd, Shawnta L / Foy, Capri G / Caban-Holt, Allison / Gwathmey, TanYa / Williams, Kelvin Lamonte / Starks, Takiyah D / Mathews, Allison / Vines, Anissa I / Richmond, Alan / Byrd, Goldie S

Journal of racial and ethnic health disparities

2023

Abstract: Background: Mistrust of the government and medical establishments are prominent reasons for vaccine hesitancy among African Americans (AAs). As COVID-19 research evolves in real time with some uncertainties remaining, AA communities may be less trusting ...

Abstract	Background: Mistrust of the government and medical establishments are prominent reasons for vaccine hesitancy among African Americans (AAs). As COVID-19 research evolves in real time with some uncertainties remaining, AA communities may be less trusting of public health agencies. The purpose of these analyses was to assess the association between trust in public health agencies that recommend the COVID-19 vaccination and COVID-19 vaccination status among AAs in North Carolina. Methods: A 75-item cross-sectional survey, the Triad Pastors Network COVID-19 and COVID-19 Vaccination survey, was developed and administered to African Americans in North Carolina. Multivariable logistic regression was used to examine the association between levels of trust in public health agencies who recommend the COVID-19 vaccine and COVID-19 vaccination status among AAs. Results: Of the 1157 AAs included in these analyses, approximately 14% of AAs had not received the COVID-19 vaccine. These findings indicated that lower levels of trust in public health agencies significantly decreased the odds of getting the COVID-19 vaccination compared to those with higher levels of trust among AAs. The most trusted source for information on COVID-19 included federal agencies among all respondents. Among the vaccinated, primary care physicians were another trusted source of information. Pastors were another trusted source for those willing to be vaccinated. Conclusions: Despite the majority of the respondents in this sample receiving the COVID-19 vaccine, subgroups of AAs remain unvaccinated. Federal agencies have a high level of trust among AA adults; however, innovative approaches are needed to reach AAs who remain unvaccinated.
Language	English
Publishing date	2023-06-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2760524-3
ISSN	2196-8837 ; 2197-3792
ISSN (online)	2196-8837
ISSN	2197-3792
DOI	10.1007/s40615-023-01646-x
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Article ; Online: Gender, Age and COVID-19 Vaccination Status in African American Adult Faith-Based Congregants in the Southeastern United States.

Foy, Capri G / Lloyd, Shawnta L / Williams, Kelvin L / Gwathmey, TanYa M / Caban-Holt, Allison / Starks, Takiyah D / Fortune, Doreen R / Ingram, LaDrea R / Byrd, Goldie S

Journal of racial and ethnic health disparities

2023

Abstract: Objectives: The COVID-19 pandemic has revealed significant differences in COVID-19 vaccination rates, with African Americans reporting lower rates compared to other racial and ethnic groups. The purpose of these analyses was to assess whether COVID-19 ... ...

Abstract	Objectives: The COVID-19 pandemic has revealed significant differences in COVID-19 vaccination rates, with African Americans reporting lower rates compared to other racial and ethnic groups. The purpose of these analyses was to assess whether COVID-19 vaccination status differed according to age in a sample of 1,240 African American adult congregants of faith-based organizations ages 18 years or older, and to examine whether this association was moderated by gender. Design: We developed and administered a 75-item cross-sectional survey, the Triad Pastor's Network COVID-19 and COVID-19 Vaccination survey, to assess experiences and perceptions regarding the COVID-19 virus and vaccines. We assessed the association between age and having received > 1 dose of a COVID-19 vaccine using unadjusted and multivariable binary logistic regression models, and the interaction of age and gender with COVID-19 vaccination status in a multivariable model. Results: Approximately 86% of participants reported having received ≥ 1 dose of a COVID-19 vaccine. The mean age (standard deviation) of the sample was 51.33 (16.62) years, and 70.9% of the sample was comprised of women. The age by gender interaction term in the multivariable model was significant (p = 0.005), prompting additional analyses stratified by gender. In women, increased age was significantly associated with higher odds of COVID-19 vaccination (odds ratio = 1.09; 95% Confidence Interval 1.06, 1.11; p < 0.001). In men, the association was not significant (p = 0.44). Conclusions: Older age was positively associated with COVID-19 vaccination in African American women, but not African American men, which may inform strategies to increase vaccination rates.
Language	English
Publishing date	2023-08-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2760524-3
ISSN	2196-8837 ; 2197-3792
ISSN (online)	2196-8837
ISSN	2197-3792
DOI	10.1007/s40615-023-01744-w
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Article: African ancestry

Rajabli, Farid / Seixas, Azizi A / Akgun, Bilcag / Adams, Larry D / Inciute, Jovita / Starks, Takiyah / Laux, Renee / Byrd, Goldie S / Haines, Jonathan L / Beecham, Gary W / Vance, Jeffery M / Cuccaro, Michael L / Pericak-Vance, Margaret A

medRxiv : the preprint server for health sciences

2023

Abstract: Cognitive and functional abilities in individuals with Alzheimer disease (AD) pathology (ADP) show greater than expected variability. While most individuals show substantial impairments in these abilities, a considerable number show little or no ... ...

Abstract	Cognitive and functional abilities in individuals with Alzheimer disease (AD) pathology (ADP) show greater than expected variability. While most individuals show substantial impairments in these abilities, a considerable number show little or no impairments. Factors contributing to this variability are not well understood. For instance, multiple studies have shown that higher levels of education are associated with reduced cognitive impairments among those with ADP. However, it remains unclear whether higher levels of education are associated with functional impairments among those with ADP. We studied 410 AA individuals with advanced levels of pTau181 (a biomarker for ADP; individuals as those having log
Language	English
Publishing date	2023-07-08
Publishing country	United States
Document type	Preprint
DOI	10.1101/2023.07.06.23292263
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Article ; Online: Self-reported experiences of discrimination and incident dementia.

Bancks, Michael P / Byrd, Goldie S / Caban-Holt, Allison / Fitzpatrick, Annette L / Forrester, Sarah N / Hayden, Kathleen M / Heckbert, Susan R / Kershaw, Kiarri N / Rapp, Stephen R / Sachs, Bonnie C / Hughes, Timothy M

Alzheimer's & dementia : the journal of the Alzheimer's Association

2023 Volume 19, Issue 7, Page(s) 3119–3128

Abstract: Introduction: Discrimination negatively impacts health and may contribute to racial/ethnic disparities in dementia risk.: Methods: Experiences of lifetime and everyday discrimination were assessed among 6509 Multi-Ethnic Study of Atherosclerosis ( ... ...

Abstract	Introduction: Discrimination negatively impacts health and may contribute to racial/ethnic disparities in dementia risk. Methods: Experiences of lifetime and everyday discrimination were assessed among 6509 Multi-Ethnic Study of Atherosclerosis (MESA) participants. We assessed the association of discrimination with incidence of dementia including adjustment for important risk factors, cohort attrition, and we assessed for effect modification by race/ethnicity. Results: Prevalence of any lifetime discrimination in MESA was 42%, highest among Black adults (72%). Over a median 15.7 years of follow-up, there were 466 incident cases of dementia. Lifetime discrimination, but not everyday discrimination, was associated with incident dementia (Wald p = 0.03). Individuals reporting lifetime discrimination in ≥2 domains (compared to none) had greater risk for dementia (hazard ratio: 1.40; 95%: 1.08, 1.82) after adjustment for sociodemographic, clinical, and behavioral risk factors. Associations did not differ by race/ethnicity. Conclusions: These findings demonstrate an association of greater experiences of lifetime discrimination with incident dementia.
MeSH term(s)	Adult ; Humans ; Black People ; Dementia/epidemiology ; Dementia/ethnology ; Dementia/etiology ; Dementia/psychology ; Ethnicity ; Risk Factors ; Self Report ; Racism/ethnology ; Racism/psychology
Language	English
Publishing date	2023-02-01
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2211627-8
ISSN	1552-5279 ; 1552-5260
ISSN (online)	1552-5279
ISSN	1552-5260
DOI	10.1002/alz.12947
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