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  1. Book ; Online: Transcending the Culture-Nature Divide in Cultural Heritage

    Byrne, Denis / O'Connor, Sue / Brockwell, Sally

    2013  

    Abstract: While considerable research and on-ground project work focuses on the interface between Indigenous/local people and nature conservation in the Asia-Pacific region, the interface between these people and cultural heritage conservation has not received the ...

    Abstract While considerable research and on-ground project work focuses on the interface between Indigenous/local people and nature conservation in the Asia-Pacific region, the interface between these people and cultural heritage conservation has not received the same attention. This collection brings together papers on the current mechanisms in place in the region to conserve cultural heritage values. It will provide an overview of the extent to which local communities have been engaged in assessing the significance of this heritage and conserving it. It will address the extent to which management regimes have variously allowed, facilitated or obstructed continuing cultural engagement with heritage places and landscapes, and discuss the problems agencies experience with protection and management of cultural heritage places
    Keywords Archaeology
    Size 1 electronic resource ( p.)
    Publisher ANU Press
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020088136
    ISBN 9781922144041 ; 9781922144058 ; 1922144045 ; 1922144053
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Waters of Belonging

    Goodall, Heather / Byrne, Denis / Cadzow, Alison / Wearing, Stephen

    2012  

    Abstract: This book arises from Parklands, Culture and Communities, a project which looks at how cultural diversity shapes peoples understandings and use of the Georges River and green spaces in Sydneys south west. Culturally diverse uses and views have not often ... ...

    Abstract This book arises from Parklands, Culture and Communities, a project which looks at how cultural diversity shapes peoples understandings and use of the Georges River and green spaces in Sydneys south west. Culturally diverse uses and views have not often been recognised in Australia in park and green space management models, which tend to be based on Anglo-Celtic norms about nature and recreation. This book focusses on the experiences of four local communities - Aboriginal, Vietnamese, Arabic and Anglo Australians - and their relationships with the river, parks and each other
    Keywords Philology. Linguistics ; Medicine (General)
    Size 1 electronic resource (55 pages)
    Publisher UTS ePRESS
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020589911
    ISBN 9780987236937 ; 0987236938
    DOI 10.5130/978-0-9872369-3-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Waterborne

    Goodall, Heather / Cadzow, Alison / Byrne, Denis / Wearing, Stephen

    2011  

    Abstract: Waterborne: Vietnamese Australians and Sydneys Georges River parks and green spaces, has been created by talking with the Vietnamese Australians who live around the Georges River and who often visit its parklands. Here they explain their memories of ... ...

    Abstract Waterborne: Vietnamese Australians and Sydneys Georges River parks and green spaces, has been created by talking with the Vietnamese Australians who live around the Georges River and who often visit its parklands. Here they explain their memories of their early homelands, which are given context with information about the histories of rivers and parks in Vietnam. The Vietnamese Australians highlighted talk about their hopes for parks in Australia and their actual experiences in the parks and rivers around their new homes near the Georges River
    Keywords Medicine (General)
    Size 1 electronic resource (43 pages)
    Publisher UTS ePRESS
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020589934
    ISBN 9780992451813 ; 0992451817
    DOI 10.5130/978-0-9924518-1-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Surface Collection

    Byrne, Denis

    Archaeological Travels in Southeast Asia

    (Worlds of Archaeology)

    2007  

    Abstract: This travelogue tackles the pressing issues of cultural-heritage management in Southern Asia by examining archaeological sites in Indonesia, Thailand, and the Philippines, among other ... ...

    Series title Worlds of Archaeology
    Abstract This travelogue tackles the pressing issues of cultural-heritage management in Southern Asia by examining archaeological sites in Indonesia, Thailand, and the Philippines, among other countries
    Language English
    Size Online-Ressource (209 p)
    Publisher AltaMira Press
    Publishing place Lanham
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9780759110175 ; 0759110174
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  5. Article ; Online: Sulfone-Mediated S

    Patel, Nitinchandra D / Wei, Xudong / Byrne, Denis / Narayanan, Bikshandarkoil A / Pennino, Scott / Sarvestani, Max / Saha, Anjan / Haddad, Nizar / Kapadia, Suresh / Lorenz, Jon C / DeCroos, Philomen / Ye, Andrew / Lee, Heewon / Grinberg, Nelu / Hossain, Azad / Busacca, Carl A / Yee, Nathan K / Senanayake, Chris H

    The Journal of organic chemistry

    2020  Volume 85, Issue 13, Page(s) 8339–8351

    Abstract: An efficient general methodology for the synthesis of 4-quinolinyl ethers is demonstrated via a highly reactive ... ...

    Abstract An efficient general methodology for the synthesis of 4-quinolinyl ethers is demonstrated via a highly reactive S
    MeSH term(s) Antiviral Agents ; Ethers ; Hepacivirus ; Hepatitis C ; Humans ; Protease Inhibitors/pharmacology ; Sulfones ; Viral Nonstructural Proteins
    Chemical Substances Antiviral Agents ; Ethers ; Protease Inhibitors ; Sulfones ; Viral Nonstructural Proteins
    Language English
    Publishing date 2020-06-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.0c00554
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Waters of Belonging

    Goodall, Heather / Byrne, Denis / Cadzow, Alison / Wearing, Stephen

    2012  

    Abstract: This book arises from Parklands, Culture and Communities, a project which looks at how cultural diversity shapes people's understandings and use of the Georges River and green spaces in Sydney's south west. Culturally diverse uses and views have not ... ...

    Abstract This book arises from Parklands, Culture and Communities, a project which looks at how cultural diversity shapes people's understandings and use of the Georges River and green spaces in Sydney's south west. Culturally diverse uses and views have not often been recognised in Australia in park and green space management models, which tend to be based on Anglo-Celtic 'norms' about nature and recreation. This book focusses on the experiences of four local communities - Aboriginal, Vietnamese, Arabic and Anglo Australians - and their relationships with the river, parks and each other.
    Keywords Social sciences ; Cultural Studies ; Ethnic & multicultural studies
    Language English
    Publisher UTS ePRESS
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Efficient Synthesis of Empagliflozin, an Inhibitor of SGLT-2, Utilizing an AlCl3-Promoted Silane Reduction of a β-Glycopyranoside

    Wang, Xiao-jun / Zhang Li / Byrne Denis / Nummy Larry / Weber Dirk / Krishnamurthy Dhileep / Yee Nathan / Senanayake Chris H

    Organic letters. 2014 Aug. 15, v. 16, no. 16

    2014  

    Abstract: An efficient production synthesis of the SGLT-2 inhibitor Empagliflozin (5) from acid 1 is described. The key tactical stage involves I/Mg exchange of aryl iodide 2 followed by addition to glucono lactone 3 in THF. Subsequent in situ treatment of the ... ...

    Abstract An efficient production synthesis of the SGLT-2 inhibitor Empagliflozin (5) from acid 1 is described. The key tactical stage involves I/Mg exchange of aryl iodide 2 followed by addition to glucono lactone 3 in THF. Subsequent in situ treatment of the resulting lactol with HCl in MeOH produces β-anomeric methyl glycopyranoside 4 which is, without isolation, directly reduced with Et₃SiH mediated by AlCl₃ as a Lewis acid in CH₂Cl₂/MeCN to afford 5 in 50% overall yield. The process was implemented for production on a metric ton scale for commercial launch.
    Keywords Lewis acids ; acetonitrile ; aluminum chloride ; chemical reactions ; chemical structure ; hydrochloric acid ; magnesium ; methanol ; methylene chloride ; organoiodine compounds ; silane
    Language English
    Dates of publication 2014-0815
    Size p. 4090-4093.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1523-7052
    DOI 10.1021%2Fol501755h
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Sulfone-Mediated SNAr Reaction as a Powerful Tool for the Synthesis of 4-Quinolinyl Ethers and More—Application to the Synthesis of HCV NS3/4a Protease Inhibitor BI 201420

    Patel, Nitinchandra D. / Wei, Xudong / Byrne, Denis / Narayanan, Bikshandarkoil A. / Pennino, Scott / Sarvestani, Max / Saha, Anjan / Haddad, Nizar / Kapadia, Suresh / Lorenz, Jon C. / DeCroos, Philomen / Ye, Andrew / Lee, Heewon / Grinberg, Nelu / Hossain, Azad / Busacca, Carl A. / Yee, Nathan K. / Senanayake, Chris H.

    Journal of organic chemistry. 2020 May 28, v. 85, no. 13

    2020  

    Abstract: An efficient general methodology for the synthesis of 4-quinolinyl ethers is demonstrated via a highly reactive SNAr reaction of 4-quinolinyl sulfones with a range of structurally diversified 1°, 2°, and 3° alcohols with a wide substrate scope and high ... ...

    Abstract An efficient general methodology for the synthesis of 4-quinolinyl ethers is demonstrated via a highly reactive SNAr reaction of 4-quinolinyl sulfones with a range of structurally diversified 1°, 2°, and 3° alcohols with a wide substrate scope and high yields. By adapting this methodology, a convergent synthesis of a complex target of HCV NS3/4a protease inhibitor BI 201420 was accomplished.
    Keywords alcohols ; ethers ; journals ; organic chemistry ; proteinase inhibitors
    Language English
    Dates of publication 2020-0528
    Size p. 8339-8351.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.0c00554
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Experimental evaluation of different methods of limiting the maximum output of hearing aids.

    Savage, Inge / Dillon, Harvey / Byrne, Denis / Bächler, Herbert

    Ear and hearing

    2006  Volume 27, Issue 5, Page(s) 550–562

    Abstract: Objective: A series of experiments designed to test the preferences of people with moderate to profound hearing losses for limiting the output of hearing aids by using peak clipping (PC), fast compression limiting (FCL), PC and FCL, and these three ... ...

    Abstract Objective: A series of experiments designed to test the preferences of people with moderate to profound hearing losses for limiting the output of hearing aids by using peak clipping (PC), fast compression limiting (FCL), PC and FCL, and these three methods in combination with slow compression limiting (SCL) was conducted.
    Design: Nineteen participants with moderate to profound sensorineural or mixed losses were recruited. In the first experiment, preferences for either PC or FCL were tested in a field trial in the participants' usual environments.A second experiment examined the acceptance of PC, FCL, and FCL + PC, using paired comparisons in a laboratory setting. The third experiment involved further paired comparisons in the laboratory to evaluate whether participants preferred PC, FCL, PC and FCL combined, or the three methods when combined with SCL.
    Results: The participants showed no statistically significant preferences for either peak clipping or fast compression limiting in the field trial. In the laboratory trial, both FCL + PC and FCL were significantly preferred over PC alone, and the addition of FCL to PC was most advantageous to participants who required the lowest maximum limiting output. The most dramatic laboratory result was the convincing preference in paired comparison testing of combining SCL with PC and/or FCL.
    Conclusions: Slow compression limiting appears to be a desirable feature in hearing aids for clients with a moderate to profound hearing loss. Preferences were not as pronounced when peak clipping, fast compression limiting, and peak clipping plus fast compression limiting were compared, but participants favored the condition that had the least amount of peak clipping.
    MeSH term(s) Adult ; Aged ; Choice Behavior ; Consumer Behavior ; Equipment Design ; Female ; Hearing Aids ; Hearing Loss, Mixed Conductive-Sensorineural/rehabilitation ; Hearing Loss, Sensorineural/rehabilitation ; Humans ; Loudness Perception/physiology ; Male ; Middle Aged
    Language English
    Publishing date 2006-10
    Publishing country United States
    Document type Evaluation Studies ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603093-2
    ISSN 1538-4667 ; 0196-0202
    ISSN (online) 1538-4667
    ISSN 0196-0202
    DOI 10.1097/01.aud.0000233982.63172.50
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Efficient synthesis of Empagliflozin, an inhibitor of SGLT-2, utilizing an AlCl3-promoted silane reduction of a β-glycopyranoside.

    Wang, Xiao-jun / Zhang, Li / Byrne, Denis / Nummy, Larry / Weber, Dirk / Krishnamurthy, Dhileep / Yee, Nathan / Senanayake, Chris H

    Organic letters

    2014  Volume 16, Issue 16, Page(s) 4090–4093

    Abstract: An efficient production synthesis of the SGLT-2 inhibitor Empagliflozin (5) from acid 1 is described. The key tactical stage involves I/Mg exchange of aryl iodide 2 followed by addition to glucono lactone 3 in THF. Subsequent in situ treatment of the ... ...

    Abstract An efficient production synthesis of the SGLT-2 inhibitor Empagliflozin (5) from acid 1 is described. The key tactical stage involves I/Mg exchange of aryl iodide 2 followed by addition to glucono lactone 3 in THF. Subsequent in situ treatment of the resulting lactol with HCl in MeOH produces β-anomeric methyl glycopyranoside 4 which is, without isolation, directly reduced with Et3SiH mediated by AlCl3 as a Lewis acid in CH2Cl2/MeCN to afford 5 in 50% overall yield. The process was implemented for production on a metric ton scale for commercial launch.
    MeSH term(s) Aluminum Compounds/chemistry ; Benzhydryl Compounds/chemical synthesis ; Benzhydryl Compounds/chemistry ; Benzhydryl Compounds/pharmacology ; Chlorides/chemistry ; Glucosides/chemical synthesis ; Glucosides/chemistry ; Glucosides/pharmacology ; Hypoglycemic Agents/chemical synthesis ; Hypoglycemic Agents/chemistry ; Hypoglycemic Agents/pharmacology ; Molecular Structure ; Oxidation-Reduction ; Silanes/chemistry ; Sodium-Glucose Transporter 2/antagonists & inhibitors
    Chemical Substances Aluminum Compounds ; Benzhydryl Compounds ; Chlorides ; Glucosides ; Hypoglycemic Agents ; Silanes ; Sodium-Glucose Transporter 2 ; aluminum chloride (3CYT62D3GA) ; empagliflozin (HDC1R2M35U)
    Language English
    Publishing date 2014-08-15
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/ol501755h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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