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Article: Influence of AS-7 on the storage lesion in young and old circulating erythrocytes.

Hsieh, Carl / Prabhu, N C Srinivasa / Rajashekaraiah, Vani

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis

2020 Volume 59, Issue 6, Page(s) 102905

Abstract: Blood and its components are stored to meet the demands of blood transfusion. Erythrocytes undergo progressive modifications during storage known as storage lesions. Storage solutions were developed to improve shelf life and extend red cell viability. ... ...

Abstract	Blood and its components are stored to meet the demands of blood transfusion. Erythrocytes undergo progressive modifications during storage known as storage lesions. Storage solutions were developed to improve shelf life and extend red cell viability. Therefore, the objective of this study is to analyze the effects of AS-7 on young and old erythrocytes during storage. Blood was collected from the blood bank at Kempegowda Institute of Medical Sciences (KIMS) hospital, Bengaluru. Erythrocytes were isolated from whole blood and separated based on its age using Percoll density gradient. The young and old erythrocytes were stored in AS-7 for 35 days and every 5th day, oxidative stress markers - Hemoglobin (Hb), Oxidative Hemolysis, Mechanical Fragility, Sialic Acid, Superoxides, Glucose, Lactate Dehydrogenase (LDH), Glutathione, antioxidant capacity (TAC
MeSH term(s)	Blood Preservation/methods ; Erythrocytes/cytology ; Erythrocytes/metabolism ; Humans ; N-Acetylneuraminic Acid/metabolism ; Oxidative Stress/drug effects
Chemical Substances	N-Acetylneuraminic Acid (GZP2782OP0)
Language	English
Publishing date	2020-08-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2046795-3
ISSN	1878-1683 ; 1473-0502
ISSN (online)	1878-1683
ISSN	1473-0502
DOI	10.1016/j.transci.2020.102905
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Article: Age-Related Modulations in Erythrocytes under Blood Bank Conditions.

Hsieh, Carl / Prabhu, N C Srinivasa / Rajashekaraiah, Vani

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

2019 Volume 46, Issue 4, Page(s) 257–266

Abstract: Background: During storage of erythrocytes, storage lesions are formed that reduce the safety and efficacy of the stored blood. Thus, there is a need to understand the changes that occur during storage. Most studies have focused on storage of a mixed ... ...

Abstract	Background: During storage of erythrocytes, storage lesions are formed that reduce the safety and efficacy of the stored blood. Thus, there is a need to understand the changes that occur during storage. Most studies have focused on storage of a mixed population of erythrocytes. The aim of this study is to analyze the changes in young and old erythrocytes over the course if storage. Materials and methods: Blood was collected from the blood bank at the Kempegowda Institute of Medical Sciences (KIMS) Hospital (Bengaluru, India) and stored for 35 days in CPDA-1 at 4°C. Every 5 days, erythrocytes were separated based on the blood's age using a Percoll-BSA gradient. Young and old erythrocytes obtained were used for analysis of the following oxidative stress (OS) markers: hemoglobin (Hb), hemolysis, mechanical fragility, antioxidant enzymes (superoxide dismutase and catalase [CAT]), superoxides, sialic acid, glutamic oxaloacetate transaminase (GOT), glucose, plasma membrane redox system (PMRS), total antioxidant capacity-cupric ion reducing antioxidant capacity assay (TAC<sub>CUPRAC</sub>), lactate dehydrogenase (LDH), lipid peroxidation products (malondialdehyde [MDA] and conjugate dienes), and protein oxidation products (advanced oxidation protein products and protein sulfhydryls). Result: Young cells had higher amounts of Hb, sialic acid, GOT, LDH, TAC<sub>CUPRAC</sub>, CAT, and superoxides compared to old cells. Old cells, however, had higher PMRS and MDA levels with respect to young cells. Discussion: Young cells could endure OS during storage more efficiently than old cells. In conclusion, the efficacy of stored blood depends on the ratio of young cells in the population. This study highlights the prospects of storing young erythrocytes for a prolonged shelf life of blood.
Language	English
Publishing date	2019-07-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2100848-6
ISSN	1660-3818 ; 1660-3796
ISSN (online)	1660-3818
ISSN	1660-3796
DOI	10.1159/000501285
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Article ; Online: Subclinical hypothyroidism - when to treat?

C. Srinivasa Rao / V. Suresh / Alok Sachan

Journal of Clinical and Scientific Research, Vol 3, Iss 2, Pp 81-

2014 Volume 84

Keywords	Medicine ; R
Language	English
Publishing date	2014-04-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Preparation of U3O8 by Calcination from Ammonium Uranyl Carbonate Using Response Surface Methodology

Liu Bingguo / Peng Jinhui / Zhang Iibo / C. Srinivasa Kannan / Hu Jin Ming / Guo Shenghui

Iranian Journal of Chemistry & Chemical Engineering, Vol 36, Iss 4, Pp 11-

Process Optimization

2017 Volume 19

Abstract: The parameters to prepare U3O8 by calcination from ammonium uranyl carbonate were optimized by using response surface methodology. A quadratic equation model for the value of total uranium and U4+ of triuranium octaoxide was built and the effects of main ...

Abstract	The parameters to prepare U3O8 by calcination from ammonium uranyl carbonate were optimized by using response surface methodology. A quadratic equation model for the value of total uranium and U4+ of triuranium octaoxide was built and the effects of main factors and their corresponding relationships were obtained. The statistical analysis of the results indicated that the value of total uranium and U4+ of triuranium octaoxide was significantly affected by the calcination temperature and calcination time in this study range. The optimized calcination conditions were determined as follows: the calcination temperature961.6 K, the calcination time 27.9 min, and the mass of material 37.86 g, respectively. Under these conditions, the value of total uranium and U4+ of triuranium octaoxide was 84.29% and 28.14%. The validity of the model was confirmed experimentally and the results were satisfactory.
Keywords	ammonium uranyl carbonate ; response surface methodology ; calcination ; u3o8 ; total uranium ; Chemical engineering ; TP155-156 ; Chemistry ; QD1-999
Language	English
Publishing date	2017-08-01T00:00:00Z
Publisher	Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Risk factors associated with COVID-19 in systemic lupus erythematosus: Results from a longitudinal prospective cohort.

Lupus

2023 Volume 32, Issue 4, Page(s) 560–564

Abstract: Introduction: Patients with SLE (systemic lupus erythematosus) have a higher risk of infection due to dysregulated immune system as well as long-term use of immunosuppressants (IS). This could influence the risk of COVID-19 and its outcome.: Methods: ...

Abstract	Introduction: Patients with SLE (systemic lupus erythematosus) have a higher risk of infection due to dysregulated immune system as well as long-term use of immunosuppressants (IS). This could influence the risk of COVID-19 and its outcome. Methods: We conducted a longitudinal prospective study across 15 rheumatology centres during the first wave of the pandemic to understand the risk factors contributing to COVID-19 in SLE patients. During the 6 months follow-up, those who tested positive for COVID-19, their clinical course and outcome information were recorded. Results: Through the study period (April-December 2020), 36/1379 lupus patients (2.9%) developed COVID-19. On analysing the COVID-19 positive versus negative cohort during the study period, male gender (adjusted RR 3.72, 95% C.I. 1.85,7.51) and diabetes (adjusted RR 2.94, 95% C.I. 1.28, 6.79) emerged as the strongest risk factors for COVID-19, in the adjusted analysis. There was no significant influence of organ involvement, hydroxychloroquine, glucocorticoid dosage (prednisolone< 7.5 mg or ≥ 7.5 mg/day) or IS on the risk of COVID-19. There was only one death (1/36) among the lupus patients due to COVID-19. Conclusion: Traditional risk factors rather than lupus disease process or IS influenced the risk of COVID-19 in our cohort.
MeSH term(s)	Humans ; Male ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/drug therapy ; Prospective Studies ; COVID-19/complications ; Longitudinal Studies ; Immunosuppressive Agents/adverse effects ; Risk Factors
Chemical Substances	Immunosuppressive Agents
Language	English
Publishing date	2023-02-02
Publishing country	England
Document type	Journal Article
ZDB-ID	1154407-7
ISSN	1477-0962 ; 0961-2033
ISSN (online)	1477-0962
ISSN	0961-2033
DOI	10.1177/09612033231155837
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Article ; Online: Drying Kinetics of Saw Dust in Tray Dryer

C. SRINIVASA KANNAN / N. BALA SUBRAMANIAN

Journal of Sustainable Development , Vol 1, Iss

2009 Volume 3

Abstract: Drying kinetics of palm wood saw in tray drying covering wide range in operating conditions have been investigated in the present study. The drying rate increased with an increase in the temperature and flow rate of the heating medium increased, and ... ...

Abstract	Drying kinetics of palm wood saw in tray drying covering wide range in operating conditions have been investigated in the present study. The drying rate increased with an increase in the temperature and flow rate of the heating medium increased, and decreased with an increase in the bed height. A model has been developed based on Fick’s law of diffusion to explain the drying kinetics.
Keywords	Environmental sciences ; GE1-350 ; Geography. Anthropology. Recreation ; G
Language	English
Publishing date	2009-02-01T00:00:00Z
Publisher	Canadian Center of Science and Education
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Management of Peanut Stem Necrosis Disease of Groundnut

Nagamani, P / Viswanath, K / Jyosthna, M K / Reddy, C Srinivasa

Indian journal of plant protection. 2013 Dec., v. 41, no. 4

2013

Abstract: Field experiments were conducted in two crop seasons during 2010–11 to study management of peanut stem necrosis disease in field condition. Among ten treatments tested in two seasons during Rabi 2010–2011 and Kharif 2011, treatment T₉ with combination of ...

Abstract	Field experiments were conducted in two crop seasons during 2010–11 to study management of peanut stem necrosis disease in field condition. Among ten treatments tested in two seasons during Rabi 2010–2011 and Kharif 2011, treatment T₉ with combination of seed treatment with imidacloprid, removal of weeds, border crop with maize, intercrop with red gram and dimethoate spray @ 2 ml/l recorded zero per cent disease incidence. This treatment followed by seed treatment with imidacloprid @ 1 ml/kg of seed+ Removal of TSV susceptible weeds+ Spray with dimethoate @ 2 ml/l 30 days after sowing recorded 1.8% disease incidence.
Keywords	Arachis hypogaea ; Cajanus cajan ; Zea mays ; application rate ; corn ; dimethoate ; disease incidence ; field experimentation ; imidacloprid ; insecticide application ; intercropping ; necrosis ; peanuts ; pigeon peas ; seed treatment ; sowing ; weeds
Language	English
Dates of publication	2013-12
Size	p. 349-352.
Publishing place	Plant Protection Association of India
Document type	Article
ISSN	2249-7870
Database	NAL-Catalogue (AGRICOLA)

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Article: Analysis of gene function in rice through virus-induced gene silencing.

Ding, Xin Shun / Rao, C Srinivasa / Nelson, Richard S

Methods in molecular biology (Clifton, N.J.)

2007 Volume 354, Page(s) 145–160

Abstract: Virus-induced gene silencing (VIGS) is a powerful RNA-silencing based technology adapted for the study of host-gene function. VIGS functions through the expression of a host gene from a virus vector. Both the virus-encoded host sequence and the ... ...

Abstract	Virus-induced gene silencing (VIGS) is a powerful RNA-silencing based technology adapted for the study of host-gene function. VIGS functions through the expression of a host gene from a virus vector. Both the virus-encoded host sequence and the homologous host target messenger RNA are destroyed or made inactive through a host surveillance system. Here, we describe procedures for the use of a new virus vector for VIGS in monocotyledonous hosts and, in particular, in rice (Oryza sativa), a species for which no VIGS vector was previously available.
MeSH term(s)	Bromovirus/pathogenicity ; Bromovirus/physiology ; Down-Regulation ; Gene Expression Regulation, Plant ; Gene Silencing ; Genes, Plant/genetics ; Genes, Plant/physiology ; Genetic Vectors ; Mutagenesis, Insertional ; Oryza/genetics ; Oryza/virology ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Plasmids/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Viral/metabolism ; Transformation, Genetic
Chemical Substances	Plant Proteins ; RNA, Messenger ; RNA, Viral
Language	English
Publishing date	2007
Publishing country	United States
Document type	Journal Article
ISSN	1064-3745
ISSN	1064-3745
DOI	10.1385/1-59259-966-4:145
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Article: Effects of Conjunctive Nutrient Management on Soil Fertility and Overall Soil Quality Index in Submountainous Inceptisol Soils under Rainfed Maize (Zea mays L.)–Wheat (Triticum aestivum) System

Sharma, K. L / Sharma, S. C / Bawa, S. S / Singh, Sher / Chandrika, D. Suma / Grace, J. Kusuma / Rao, C. Srinivasa / Sankar, G. R. Maruthi / Ravindrachary, G / Munnalal / Kumar, T. Satish / Gajbhiye, Pravin G / Rani, K. Usha / Indoria, A. K

Communications in soil science and plant analysis. 2015 Jan. 2, v. 46, no. 1

2015

Abstract: The present long-term study was initiated to quantify the long-term effects of conjunctive nutrient management on soil quality, identify key indicators, and assess soil quality indices under a rainfed maize–wheat system in marginal Inceptisol soils in ... ...

Abstract	The present long-term study was initiated to quantify the long-term effects of conjunctive nutrient management on soil quality, identify key indicators, and assess soil quality indices under a rainfed maize–wheat system in marginal Inceptisol soils in India. Results of the study revealed that soil organic carbon was significantly influenced by the conjunctive nutrient-management treatments. Among the nine treatments, the application of 100% recommended dose of nitrogen (RDN) (80 kg N ha ⁻¹), 15 kg N (compost) + 20 kg N ha ⁻¹ (inorganic), 25 kg N (compost), and 15 kg N (compost) + 10 kg N ha ⁻¹ (green leaf) resulted in greater organic carbon contents of 5.57, 5.32, 5.27, and 5.26 g kg ⁻¹, which were greater by 29.5%, 24%, 23%, and 22%, respectively, over the control. The greatest soil quality index (1.61) was observed with application of 25 kg nitrogen (N; compost) as well as with application of 15 kg N (compost) + 10 kg N ha ⁻¹ (green leaf). The order of percentage contribution of key indicators toward soil quality indices was available potassium (K) (34%) > available phosphorus (P) (32%) > available N (13%) > microbial biomass carbon (12%) > exchangeable calcium (Ca) (9%). The linear regression equation revealed the principal role of soil quality indicators in maize crop yield. The methodology and the results of the study could be of great relevance in improving and assessing soil quality not only for the study locations but also for other climatically and edaphically identical regions across the world.
Keywords	Inceptisols ; Triticum aestivum ; Zea mays ; calcium ; carbon ; composts ; corn ; crop yield ; equations ; exchangeable calcium ; leaves ; linear models ; long term effects ; microbial biomass ; nitrogen ; nutrient management ; phosphorus ; potassium ; soil fertility ; soil organic carbon ; soil quality ; India
Language	English
Dates of publication	2015-0102
Size	p. 47-61.
Publishing place	Taylor & Francis
Document type	Article
ZDB-ID	419718-5
ISSN	1532-2416 ; 0010-3624
ISSN (online)	1532-2416
ISSN	0010-3624
DOI	10.1080/00103624.2014.956885
Database	NAL-Catalogue (AGRICOLA)

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Article: Effects of Conjunctive Nutrient Management on Soil Fertility and Overall Soil Quality Index in Submountainous Inceptisol Soils under Rainfed Maize (Zea mays L.) - Wheat(Triticum aestivum) System

Sharma, K. L. / Sharma, S. C. / Bawa, S. S. / Singh, Sher / Chandrika, D. Suma / Grace, J. Kusuma / Rao, C. Srinivasa / Sankar, G. R. Maruthi / Ravindrachary, G. / Munnalal / Kumar, T. Satish / Gajbhiye, Pravin G. / Rani, K. Usha / Indoria, A. K

Communications in soil science and plant analysis

2015 Volume 46, Issue 1/3, Page(s) 47

Language	English
Document type	Article
ZDB-ID	419718-5
ISSN	0010-3624
Database	Current Contents Nutrition, Environment, Agriculture

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