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Article ; Online: Epidemiological, Clinical, and Allergic Profile of Psoriatic Patients. Evaluation of the Spanish Registry of Contact Dermatitis and Cutaneous Allergy (REIDAC).

Verdaguer-Faja, J / Borrego, L / Mercader-García, P / González Pérez, R / Córdoba-Guijarro, S / Giménez-Arnau, A M / Ruiz-González, I / Miquel-Miquel, J / Silvestre, J F / Ortiz de Frutos, F J / Tous-Romero, F / Sanz Sánchez, T / Rodríguez-Serna, M / Sánchez-Pérez, J / Serra Baldrich, E / Zaragoza-Ninet, V / Pastor-Nieto, M A / Gática-Ortega, M E / Sánchez Gilo, A /

Melé-Ninot, G / Sánchez-Pedreño Guillén, P / Munera-Campos, M / Descalzo, M Á / García-Doval, I / Carrascosa, J M

Actas dermo-sifiliograficas

2024

Abstract: Background: Psoriasis is a chronic inflammatory dermatosis whose clinical and topographic distribution requires differential diagnosis, or the possible association with allergic contact dermatitis (ACD), requiring patch testing (PT) as part of the ... ...

Title translation	Perfil epidemiológico, clínico y alérgico en pacientes con psoriasis. Evaluación del Registro Español de Dermatitis de Contacto (REIDAC).
Abstract	Background: Psoriasis is a chronic inflammatory dermatosis whose clinical and topographic distribution requires differential diagnosis, or the possible association with allergic contact dermatitis (ACD), requiring patch testing (PT) as part of the diagnostic procedure. Objectives: To describe the epidemiological, clinical, and allergic profile of patients with a primary or secondary diagnosis of psoriasis undergoing PT and compare them with patients with a diagnosis of ACD at the end of the diagnostic process. Methods: Cross-sectional study with data from REIDAC from 2018 through 2023 of selected patients with a diagnosis of psoriasis and/or ACD. Results: A total of 11 502 patients were included, 513 of whom had been diagnosed with primary or secondary psoriasis, 3640 with ACD, and 108 with both diseases. Men were more predominant in the groups of patients with psoriasis, psoriasis+ACD, and lesions were more predominantly seen in the hands with little association with atopic factors vs the ACD group. The rate of positivity in PT to the 2022 Spanish battery of allergens was lower in the group with psoriasis only in 27% of the patients. The most common allergens found in the psoriasis group were also the most common ones found in the overall ACD population. Conclusions: Overall, 36.2% of psoriatic patients tested positive in PT to the 2022 Spanish battery of allergens, which proved that this association is not uncommon. Overall, psoriatic patients had a higher mean age, were more predominantly men, and showed more hand involvement.
Language	Spanish
Publishing date	2024-02-19
Publishing country	Spain
Document type	Journal Article
ZDB-ID	390255-9
ISSN	1578-2190 ; 0001-7310 ; 1138-8196
ISSN (online)	1578-2190
ISSN	0001-7310 ; 1138-8196
DOI	10.1016/j.ad.2024.02.009
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Article ; Online: [Translated article] Four-year Epidemiological Surveillance of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy: Current Situation and Trends.

Tous-Romero, F / Borrego-Hernando, L / García-Doval, I / Mercader-García, P / Silvester-Salvador, J F / Sánchez-Gilo, A / Sanz-Sánchez, T / Giménez-Arnau, A M / Zaragoza-Ninet, V / Miquel-Miquel, J / González Pérez, R / Córdoba-Guijarro, S / Carrascosa-Carrillo, J M / Gática-Ortega, M E / Ruíz-González, I / Serra-Baldrich, E / Pastor-Nieto, A / Rodríguez-Serna, M / Sánchez-Pérez, J /

Melé I Ninot, G / Sánchez-Pedreño Guillén, P / Ortiz-de Frutos, J

Actas dermo-sifiliograficas

2024 Volume 115, Issue 4, Page(s) T331–T340

Abstract: Background: The epidemiological surveillance of contact dermatitis is one of the objectives of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy. Knowing whether the prevalence of positive tests to the different allergens ... ...

Abstract	Background: The epidemiological surveillance of contact dermatitis is one of the objectives of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy. Knowing whether the prevalence of positive tests to the different allergens changes over time is important for this monitoring process. Objectives: To describe the various temporary trends in allergen positivity in the GEIDAC standard series from 2018 through December 31, 2022. Methods: This was a multicenter, observational trial of consecutive patients analyzed via patch tests as part of the study of possible allergic contact dermatitises collected prospectively within the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy. The data was analyzed using 2 statistical tests: one homogeneity test (to describe the changes seen over time) and one trend test (to see whether the changes described followed a linear trend). Results: A total of 11327 patients were included in the study. Overall, the allergens associated with a highest sensitization were nickel sulfate, methylisothiazolinone, cobalt chloride, methylchloroisothiazolinone/methylisothiazolinone, and fragrance mix i. A statistically significant decrease was found in the percentage of methylisothiazolinone positive tests across the study years with an orderly trend. Conclusions: Although various changes were seen in the sensitizations trends to several allergens of the standard testing, it became obvious that a high sensitization to nickel, methylchloroisothiazolinone/methylisothiazolinone and fragrances mix i remained. Only a significant downward trend was seen for methylisothiazolinone.
MeSH term(s)	Humans ; Allergens ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/epidemiology ; Dermatitis, Allergic Contact/etiology ; Dermatitis, Atopic ; Patch Tests ; Retrospective Studies ; Thiazoles
Chemical Substances	2-methyl-4-isothiazolin-3-one (229D0E1QFA) ; 5-chloro-2-methyl-4-isothiazolin-3-one (DEL7T5QRPN) ; Allergens ; Thiazoles
Language	Spanish
Publishing date	2024-02-07
Publishing country	Spain
Document type	Observational Study ; Multicenter Study ; Journal Article
ZDB-ID	390255-9
ISSN	1578-2190 ; 0001-7310 ; 1138-8196
ISSN (online)	1578-2190
ISSN	0001-7310 ; 1138-8196
DOI	10.1016/j.ad.2024.02.006
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Article ; Online: [[Translated article]]Epidemiological, Clinical, and Allergic Profile of Psoriatic Patients. Evaluation of the Spanish Registry of Contact Dermatitis and Cutaneous Allergy (REIDAC).

Verdaguer-Faja, J / Borrego, L / Mercader-García, P / González Pérez, R / Córdoba-Guijarro, S / Giménez-Arnau, A M / Ruiz-González, I / Miquel-Miquel, J / Francisco Silvestre, J / Ortiz de Frutos, F J / Tous-Romero, F / Sanz Sánchez, T / Rodríguez-Serna, M / Sánchez-Pérez, J / Serra Baldrich, E / Zaragoza-Ninet, V / Pastor-Nieto, M A / Gatica-Ortega, M E / Sánchez Gilo, A /

Melé-Ninot, Gemma / Sánchez-Pedreño Guillén, P / Munera-Campos, M / Descalzo, M Á / García-Doval, I / Carrascosa, J M

Actas dermo-sifiliograficas

2024

Abstract	Background: Psoriasis is a chronic inflammatory dermatosis whose clinical and topographic distribution requires differential diagnosis, or the possible association with allergic contact dermatitis (ACD), requiring patch testing (PT) as part of the diagnostic procedure. Objectives: To describe the epidemiological, clinical, and allergic profile of patients with a primary or secondary diagnosis of psoriasis undergoing PT and compare them with patients with a diagnosis of ACD at the end of the diagnostic process. Methods: Cross-sectional study with data from REIDAC from 2018 through 2023 of selected patients with a diagnosis of psoriasis and/or ACD. Results: A total of 11 502 patients were included, 513 of whom had been diagnosed with primary or secondary psoriasis, 3640 with ACD, and 108 with both diseases. Men were more predominant in the groups of patients with psoriasis, psoriasis + ACD, and lesions were more predominantly seen in the hands with little association with atopic factors vs the ACD group. The rate of positivity in PT to the 2022 Spanish battery of allergens was lower in the group with psoriasis only in 27% of the patients. The most common allergens found in the psoriasis group were also the most common ones found in the overall ACD population. Conclusions: Overall, 36.2% of psoriatic patients tested positive in PT to the 2022 Spanish battery of allergens, which proved that this association is not uncommon. Overall, psoriatic patients had a higher mean age, were more predominantly men, and showed more hand involvement.
Language	Spanish
Publishing date	2024-04-20
Publishing country	Spain
Document type	Journal Article
ZDB-ID	390255-9
ISSN	1578-2190 ; 0001-7310 ; 1138-8196
ISSN (online)	1578-2190
ISSN	0001-7310 ; 1138-8196
DOI	10.1016/j.ad.2024.04.013
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Article ; Online: Linear exophytic tumor on the dorsum of the tongue.

Meseguer-Yebra, C / Córdoba-Guijarro, S / Borbujo, J

Actas dermo-sifiliograficas

2013 Volume 104, Issue 5, Page(s) 435–436

MeSH term(s)	Aged ; Glossitis/pathology ; Humans ; Hypertrophy ; Male ; Tongue/pathology
Language	Spanish
Publishing date	2013-06
Publishing country	Spain
Document type	Case Reports ; Journal Article
ZDB-ID	390255-9
ISSN	1578-2190 ; 0001-7310 ; 1138-8196
ISSN (online)	1578-2190
ISSN	0001-7310 ; 1138-8196
DOI	10.1016/j.adengl.2013.04.007
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Article ; Online: Four-year Epidemiological Surveillance of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy: Current Situation and Trends.

Melé I Ninot, G / Sánchez-Pedreño Guillén, P / Ortiz-de Frutos, J

Actas dermo-sifiliograficas

2023 Volume 115, Issue 4, Page(s) 331–340

Title translation	Vigilancia epidemiológica en los últimos 4 años del Registro Español de Investigación en Dermatitis de Contacto y Alergia Cutánea: situación actual y tendencias.
Abstract	Background: The epidemiological surveillance of contact dermatitis is one of the objectives of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy. Knowing whether the prevalence of positive tests to the different allergens changes over time is important for this monitoring process. Objectives: To describe the various temporary trends in allergen positivity in the GEIDAC standard series from 2018 through December 31, 2022. Methods: This was a multicenter, observational trial of consecutive patients analyzed via patch tests as part of the study of possible allergic contact dermatitises collected prospectively within the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy. The data was analyzed using 2 statistical tests: one homogeneity test (to describe the changes seen over time) and one trend test (to see whether the changes described followed a linear trend). Results: A total of 11327 patients were included in the study. Overall, the allergens associated with a highest sensitization were nickel sulfate, methylisothiazolinone, cobalt chloride, methylchloroisothiazolinone/methylisothiazolinone, and fragrance mix i. A statistically significant decrease was found in the percentage of methylisothiazolinone positive tests across the study years with an orderly trend. Conclusions: Although various changes were seen in the sensitizations trends to several allergens of the standard testing, it became obvious that a high sensitization to nickel, methylchloroisothiazolinone/methylisothiazolinone and fragrances mix i remained. Only a significant downward trend was seen for methylisothiazolinone.
MeSH term(s)	Humans ; Thiazoles ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/epidemiology ; Dermatitis, Allergic Contact/etiology ; Allergens/adverse effects ; Dermatitis, Atopic ; Patch Tests ; Retrospective Studies
Chemical Substances	5-chloro-2-methyl-4-isothiazolin-3-one (DEL7T5QRPN) ; 2-methyl-4-isothiazolin-3-one (229D0E1QFA) ; Thiazoles ; Allergens
Language	Spanish
Publishing date	2023-12-05
Publishing country	Spain
Document type	Observational Study ; Multicenter Study ; Journal Article
ZDB-ID	390255-9
ISSN	1578-2190 ; 0001-7310 ; 1138-8196
ISSN (online)	1578-2190
ISSN	0001-7310 ; 1138-8196
DOI	10.1016/j.ad.2023.10.039
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Article ; Online: Standard and Expanded Series Patch Testing Update by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC).

Navarro-Triviño, F J / Borrego, L / Silvestre-Salvador, J F / Mercader-García, P / Giménez-Arnau, A M / Ortiz-de Frutos, F J / Sanz-Sánchez, T / Melé-Ninot, G / Sánchez-Gilo, A / Zaragoza-Ninet, V / Serra-Baldrich, E / Miquel-Miquel, J / Córdoba-Guijarro, S / Rodríguez-Serna, M / Ruíz-González, I / Carrascosa-Carrillo, J M / Gómez-de la Fuente, E / Pastor-Nieto, M A / Heras-Mendaza, F /

González-Pérez, R / Sánchez-Pedreño Guillén, P / Sánchez-Pérez, J / Gatica-Ortega, M E / Fernández-Redondo, V / Hervella-Garcés, M / Manrique-Martínez, P / Guimaraens-Juanena, D / García-Gavín, J / Giménez-Arnau, E / Figueras-Nart, I / Curto-Barredo, L / Armario-Hita, J C

Actas dermo-sifiliograficas

2024

Abstract: After the meeting held by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC) back in October 2021, changes were suggested to the Spanish standard series patch testing. Hydroxyethyl methacrylate (2% pet.), textile dye mixt (6.6% pet.), ...

Title translation	Actualización de la batería estándar y batería ampliada de pruebas alérgicas de contacto por el Grupo Español de Investigación en Dermatitis de Contacto y Alergia Cutánea (GEIDAC).
Abstract	After the meeting held by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC) back in October 2021, changes were suggested to the Spanish standard series patch testing. Hydroxyethyl methacrylate (2% pet.), textile dye mixt (6.6% pet.), linalool hydroperoxide (1% pet.), and limonene hydroperoxide (0.3% pet.) were, then, added to the series that agreed upon in 2016. Ethyldiamine and phenoxyethanol were excluded. Methyldibromoglutaronitrile, the mixture of sesquiterpene lactones, and hydroxyisohexyl 3-cyclohexene (Lyral) were alo added to the extended Spanish series of 2022.
Language	Spanish
Publishing date	2024-03-29
Publishing country	Spain
Document type	Practice Guideline
ZDB-ID	390255-9
ISSN	1578-2190 ; 0001-7310 ; 1138-8196
ISSN (online)	1578-2190
ISSN	0001-7310 ; 1138-8196
DOI	10.1016/j.ad.2024.03.024
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Article ; Online: Polysensitization in the Spanish Contact Dermatitis Registry (REIDAC): A 2019-2022 prospective study with cluster and network analysis.

Pesqué, David / Borrego, Leopoldo / Zaragoza-Ninet, Violeta / Sanz-Sánchez, Tatiana / Miquel-Miquel, Francisco Javier / González-Pérez, Ricardo / Silvestre, Juan Francisco / Córdoba-Guijarro, Susana / Carrascosa, José Manuel / Gatica-Ortega, María Elena / Ruiz-González, Inmaculada / Mercader-García, Pedro / Tous-Romero, Fátima / Ortiz de Frutos, Francisco Javier / Serra-Baldrich, Esther / Pastor-Nieto, María Antonia / Rodríguez-Serna, Mercedes / Sánchez-Pérez, Javier / Sánchez-Gilo, Araceli /

Melé-Ninot, Gemma / Sánchez-Pedreño Guillén, Paloma / Pujol, Ramon Maria / Giménez-Arnau, Ana María

Journal of the European Academy of Dermatology and Venereology : JEADV

2024

Abstract: Background: There is still limited clinical-practice data on specific clinical and patch test features, as well as on allergen clusters in polysensitization (PS).: Objectives: To determine the frequency, relevance, symptoms duration and risk factors ... ...

Abstract	Background: There is still limited clinical-practice data on specific clinical and patch test features, as well as on allergen clusters in polysensitization (PS). Objectives: To determine the frequency, relevance, symptoms duration and risk factors in polysensitized patients and to assess possible allergen aggregation. Methods: Prospective multicentric study (January 2019-December 2022) conducted in setting of the Spanish Contact Dermatitis Register (REIDAC). Clinical and patch test data of polysensitized and oligosensitized patients were compared, and risk factors of PS were investigated with logistic multivariate regression. Unsupervised hierarchical clustering and network analysis were used to study allergen aggregation in PS. Results: A total of 10,176 patients were analysed. PS was found in 844 (8.3%). Current relevance was significantly higher in polysensitized patients (p < 0.01). Risk factors for PS were atopic dermatitis (OR: 1.58, 95% CI: 1.24-2.02), age (≥60 years vs. ≤24 years, OR: 1.75, 95% CI: 1.25-2.44) and some special locations (legs vs. face OR: 1.54, 95% CI: 1.05-2.25, hands vs. face OR: 1.46, 95% CI:1.15-1.85, arms vs. face OR: 1.49, 95% CI:1.01-2.20, trunk vs. face OR: 1.40, 95% CI:1.06-1.85). Cluster and network analyses revealed specific-allergen clusters and significant associations, including allergens belonging to metals group, fragrances and botanicals group, topical drugs group, rubber allergens and biocides. Conclusions: This study confirms that PS is structured by discernible patterns of specific-allergen clusters and reinforces significant allergen associations in PS. Cross-reactivity and/or concomitant sensitization could explain the formation of allergen clusters in PS.
Language	English
Publishing date	2024-02-27
Publishing country	England
Document type	Journal Article
ZDB-ID	1128828-0
ISSN	1468-3083 ; 0926-9959
ISSN (online)	1468-3083
ISSN	0926-9959
DOI	10.1111/jdv.19934
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Zs.A 3492: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Sensitization to textile dyes in Spain: Epidemiological situation (2019-2022).

Hernández Fernández, Carlos Pelayo / Borrego, Leopoldo / Giménez Arnau, Ana María / Zaragoza Ninet, Violeta / Sanz Sánchez, Tatiana / Miquel Miquel, Francisco Javier / González Pérez, Ricardo / Silvestre Salvador, Juan Francisco / Córdoba Guijarro, Susana / Carrascosa Carrillo, José Manuel / Gatica Ortega, María Elena / Ruiz González, Inmaculada / Mercader García, Pedro / Tous Romero, Fátima / Serra Baldrich, Esther / Pastor-Nieto, María Antonia / Rodríguez Serna, Mercedes / Sánchez Pérez, Javier / Sánchez Gilo, Araceli /

Melé Ninot, Gemma / Sánchez-Pedreño Guillén, Paloma / de Vega Martínez, Marina / Descalzo, Miguel Ángel Gallego / Doval, Ignacio García

Contact dermatitis

2024 Volume 90, Issue 5, Page(s) 486–494

Abstract: Background: Current frequency and features for positivity to textile dye mix (TDM) in Spain are unknown.: Objectives: To study the frequency, clinical features and simultaneous positivity between TDM, para-phenylenediamine (PPD) and specific disperse ...

Abstract	Background: Current frequency and features for positivity to textile dye mix (TDM) in Spain are unknown. Objectives: To study the frequency, clinical features and simultaneous positivity between TDM, para-phenylenediamine (PPD) and specific disperse dyes. Materials and methods: We analysed all consecutive patients patch-tested with TDM from the Spanish Contact Dermatitis Registry (REIDAC), from 1 January 2019 to 31 December 2022. Within this group, we studied all selected patients patch-tested with a textile dye series. Results: Out of 6128 patients analysed, 3.3% were positive to the TDM and in 34% of them, the sensitization was considered currently relevant. TDM positivity was associated with working as a hairdresser/beautician and scalp, neck/trunk and arm/forearm dermatitis. From TDM-positive patients, 57% were positive to PPD. One hundred and sixty-four patients were patch-tested with the textile dye series. Disperse Orange 3 was the most frequent positive dye (16%). One of every six cases positive to any dye from the textile dye series would have been missed if patch-tested with the TDM alone. Conclusions: Positivity to TDM is common in Spain and often associated with PPD sensitization. TDM is a valuable marker of disperse dyes allergy that should be part of the Spanish and European standard series.
MeSH term(s)	Humans ; Dermatitis, Allergic Contact/epidemiology ; Dermatitis, Allergic Contact/etiology ; Spain/epidemiology ; Textiles/adverse effects ; Patch Tests ; Coloring Agents/adverse effects
Chemical Substances	Coloring Agents
Language	English
Publishing date	2024-02-13
Publishing country	England
Document type	Journal Article
ZDB-ID	193121-0
ISSN	1600-0536 ; 0105-1873
ISSN (online)	1600-0536
ISSN	0105-1873
DOI	10.1111/cod.14513
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Article ; Online: Chronic nonscarring scalp folliculitis: Retrospective case series study of 34 cases.

Romero-Maté, Alberto / Arias-Palomo, Dolores / Hernández-Núñez, Almudena / Córdoba-Guijarro, Susana / Borbujo-Martínez, Jesús

Journal of the American Academy of Dermatology

2019 Volume 81, Issue 4, Page(s) 1023–1024

MeSH term(s)	Adult ; Age of Onset ; Anti-Bacterial Agents/therapeutic use ; Bacteria/isolation & purification ; Biopsy ; Chronic Disease ; Dermatologic Agents/therapeutic use ; Folliculitis ; Follow-Up Studies ; Hair Follicle/microbiology ; Hair Follicle/pathology ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Scalp Dermatoses ; Treatment Outcome ; Young Adult
Chemical Substances	Anti-Bacterial Agents ; Dermatologic Agents
Language	English
Publishing date	2019-03-11
Publishing country	United States
Document type	Letter
ZDB-ID	603641-7
ISSN	1097-6787 ; 0190-9622
ISSN (online)	1097-6787
ISSN	0190-9622
DOI	10.1016/j.jaad.2019.02.065
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Article ; Online: Patch Testing in Patients With Severe Atopic Dermatitis Treated With Dupilumab: A Multicentric Approach in Spain.

Docampo-Simón, Alexandre / Sánchez-Pujol, María J / Pastor-Nieto, Maria A / Giménez-Arnau, Ana / Rodríguez-Serna, Mercedes / Serra-Baldrich, Esther / Miquel, Javier / Sánchez-Pérez, Javier / Sanz-Sánchez, Tatiana / Zaragoza-Ninet, Violeta / Sánchez-Pedreño, Paloma / Carrascosa, Jose M / Gatica-Ortega, Maria E / Fernández-Redondo, Virginia / Córdoba-Guijarro, Susana / González-Pérez, Ricardo / Silvestre, Juan F

Dermatitis : contact, atopic, occupational, drug

2023 Volume 34, Issue 4, Page(s) 315–322

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Humans ; Dermatitis, Atopic/epidemiology ; Patch Tests ; Spain/epidemiology ; Treatment Outcome ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/epidemiology ; Dermatitis, Allergic Contact/etiology ; Severity of Illness Index
Chemical Substances	dupilumab (420K487FSG)
Language	English
Publishing date	2023-03-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	2144723-8
ISSN	2162-5220 ; 1532-8163 ; 1710-3568
ISSN (online)	2162-5220 ; 1532-8163
ISSN	1710-3568
DOI	10.1089/derm.2022.0023
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