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Article ; Online: Emotional intelligence as a predictor of job satisfaction

Iris Soriano-Vázquez / Mayela Cajachagua Castro / Wilter C. Morales-García

Frontiers in Public Health, Vol

the mediating role of conflict management in nurses

2023 Volume 11

Abstract: BackgroundEmotional Intelligence (EI) has emerged as a pivotal factor in work effectiveness and well-being within the healthcare domain. Specifically, its significance is heightened in the nursing sector, where emotional and social demands are high. ... ...

Abstract	BackgroundEmotional Intelligence (EI) has emerged as a pivotal factor in work effectiveness and well-being within the healthcare domain. Specifically, its significance is heightened in the nursing sector, where emotional and social demands are high. Additionally, job satisfaction and conflict management are recognized as vital predictors of patient care service quality. However, there is a dearth of research addressing the mediating role of conflict management in the relationship between EI and job satisfaction within a nursing context.ObjectiveThis study aims to assess the mediating role of conflict management in the relationship between emotional intelligence and job satisfaction among nurses.MethodsThe STROBE checklist for cross-sectional studies was followed. A cross-sectional and explanatory design was employed. Data were collected using self-reported questionnaires to measure emotional intelligence, conflict management, and job satisfaction. Structural Equation Modeling (SEM) was conducted to test the proposed hypotheses.ResultsA total of 208 nurses aged between 18 and 65 years participated (M = 41.18, SD = 8.942). The findings confirmed a positive relationship between emotional intelligence and conflict management (β = 0.64, p < 0.001). Similarly, a positive relationship between conflict management and job satisfaction was observed (β = 0.37, p < 0.001). Moreover, conflict management was validated as a mediator in the relationship between emotional intelligence and job satisfaction (β = 0.77, p = 0.002).ConclusionThe study underscores the importance of emotional intelligence and conflict management as predictors of job satisfaction in nurses. The results suggest that interventions aimed at enhancing emotional intelligence might be an effective avenue for increasing job satisfaction, especially when conflict management strategies are integrated.
Keywords	emotional intelligence ; conflict management ; job satisfaction ; nurses ; mediation ; Public aspects of medicine ; RA1-1270
Subject code	150
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Involvement of POLA2 in Double Strand Break Repair and Genotoxic Stress

Tuyen T. Dang / Julio C. Morales

International Journal of Molecular Sciences, Vol 21, Iss 4245, p

2020 Volume 4245

Abstract: Cellular survival is dependent on the efficient replication and transmission of genomic information. DNA damage can be introduced into the genome by several different methods, one being the act of DNA replication. Replication is a potent source of DNA ... ...

Abstract	Cellular survival is dependent on the efficient replication and transmission of genomic information. DNA damage can be introduced into the genome by several different methods, one being the act of DNA replication. Replication is a potent source of DNA damage and genomic instability, especially through the formation of DNA double strand breaks (DSBs). DNA polymerase alpha is responsible for replication initiation. One subunit of the DNA polymerase alpha replication machinery is POLA2. Given the connection between replication and genomic instability, we decided to examine the role of POLA2 in DSB repair, as little is known about this topic. We found that loss of POLA2 leads to an increase in spontaneous DSB formation. Loss of POLA2 also slows DSB repair kinetics after treatment with etoposide and inhibits both of the major double strand break repair pathways: non-homologous end-joining and homologous recombination. In addition, loss of POLA2 leads to increased sensitivity to ionizing radiation and PARP1 inhibition. Lastly, POLA2 expression is elevated in glioblastoma multiforme tumors and correlates with poor overall patient survival. These data demonstrate a role for POLA2 in DSB repair and resistance to genotoxic stress.
Keywords	POLA2 ; homologous recombination (HR) ; non-homologous end-joining (NHEJ) ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	570
Language	English
Publishing date	2020-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Utilidad de la ecografía cutánea para el diagnóstico de la malformación venosa verrucosa

V. Amat-Samaranch / C. Morales-Múnera / L. Puig / E Roé

Actas Dermo-Sifiliográficas, Vol 112, Iss 10, Pp 958-

2021 Volume 961

Keywords	Dermatology ; RL1-803 ; Internal medicine ; RC31-1245
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Prevalencia de alteraciones buco-dentales en una muestra de pacientes con Síndrome de Down

Mariana C. Morales-Chávez / Anabel Serrano-Llorca / Verónica Bego-Volcán

Odous Científica, Vol 22, Iss

2021 Volume 1

Abstract: El Síndrome de Down (SD) es la primera causa genética de discapacidad intelectual causado por una trisomía en el cromosoma 21. Los pacientes con síndrome de Down suelen presentar características bucales particulares asociadas a su condición. El objetivo ... ...

Abstract	El Síndrome de Down (SD) es la primera causa genética de discapacidad intelectual causado por una trisomía en el cromosoma 21. Los pacientes con síndrome de Down suelen presentar características bucales particulares asociadas a su condición. El objetivo de esta investigación fue determinar la prevalencia de alteraciones bucodentales en un grupo de pacientes con Síndrome de Down. Se realizó un estudio observacional de corte transversal con una muestra de 92 pacientes con SD con edades comprendidas entre 13 y 55 años. Los resultados encontrados fueron: 51,08% tenían enfermedades sistémicas, el 53% presentó caries, el 53,2% gingivitis, el 47% maloclusiones y el 72% hábitos parafuncionales. Se concluye que en esta muestra las alteraciones bucodentales más prevalentes fueron la enfermedad periodontal y las maloclusiones.
Keywords	síndrome de Down ; maloclusiones ; enfermedad periodontal ; Dentistry ; RK1-715 ; Medicine (General) ; R5-920
Language	Spanish
Publishing date	2021-02-01T00:00:00Z
Publisher	Universidad de Carabobo
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Validity and Reliability of a Brief Scale of Intention to Vaccinate Against COVID-19 in a Peruvian Sample

Wilter C. Morales-García / Salomón Huancahuire-Vega / JackSaint Saintila / Percy G. Ruiz Mamani

Journal of Primary Care & Community Health, Vol

2022 Volume 13

Abstract: Objective: This study aimed to analyze the psychometric properties of a brief scale measuring intention to vaccinate against COVID-19 in a Peruvian sample in the context of the current pandemic. Methods: A cross-sectional and instrumental study was ... ...

Abstract	Objective: This study aimed to analyze the psychometric properties of a brief scale measuring intention to vaccinate against COVID-19 in a Peruvian sample in the context of the current pandemic. Methods: A cross-sectional and instrumental study was carried out. A total of 547 Peruvian citizens selected through non-probability convenience sampling participated. Considering existing theories of vaccination hesitancy, 12 items were proposed that evaluate the intention to vaccinate against COVID-19 and the internal structure was evaluated through exploratory and confirmatory factor analysis. Reliability was analyzed with the ordinal alpha coefficient. Results: The exploratory factor analysis yielded a structure of 2 oblique factors that explain 69% of the total variance and the items saturated between 0.52 and 0.97. The confirmatory factor analysis showed that, of 4 models analyzed, the fourth model that was composed of 6 items presented optimal indices of goodness-of-fit ( X 2 = 11.089, P = .197, CFI = 0.999, TLI = 0.999, RMSEA = 0.034 [IC 90%, 0.000-0.077], SRMR = 0.016). Reliability analysis through the ordinal alpha coefficient yielded that the brief scale of intention to vaccinate against COVID-19 has adequate internal consistency (α = .91). Conclusions: The brief scale of intention to vaccinate against COVID-19 presents adequate psychometric properties that demonstrate validity and reliability and can be used in future research and clinical practice.
Keywords	Computer applications to medicine. Medical informatics ; R858-859.7 ; Public aspects of medicine ; RA1-1270
Subject code	310
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Predictors of Depression in Nurses During COVID-19 Health Emergency; the Mediating Role of Resilience

Sonia Chura / Jacksaint Saintila / Rut Mamani / Percy G. Ruiz Mamani / Wilter C. Morales-García

Journal of Primary Care & Community Health, Vol

A Cross-Sectional Study

2022 Volume 13

Abstract: Background: Nurses are susceptible to several mental problems, such as fear, stress, and depression due to the COVID-19 pandemic, which affects their emotional well-being. However, resilience plays an important role in mitigating the effects of COVID-19. ...

Abstract	Background: Nurses are susceptible to several mental problems, such as fear, stress, and depression due to the COVID-19 pandemic, which affects their emotional well-being. However, resilience plays an important role in mitigating the effects of COVID-19. Objective: This study was to examine the mediating role of resilience in the relation between fear, stress, and depression of nurses during COVID-19 health emergencies. Methods: A cross-sectional—predictive study was carried out. The variables analyzed were fear, resilience, stress, and depression. A total of 286 nurses from 2 hospitals in the cities of Juliaca and Puno, Peru. Data analyses were performed using structural equation modeling (SEM). Results: Analyses showed that the variables were significantly related ( P < .01). In addition, a confirmatory analysis of the hypothesized model using structural equation modeling shows that fear and stress are predictors of depression, and that resilience plays a role in mediating the effect of fear on stress ( X 2 = 534.69, gl = 372, P = .000; TLI = .902, CFI = .910, RMSEA = .039 [95% CI = 0.032-0.046], and SRMR = .065). Conclusion: Nurses tend to develop fear, stress, and depression. Resilience reduces the impact of these psychological variables. Hospital management should provide psychological support and training for nurses in coping strategies.
Keywords	Computer applications to medicine. Medical informatics ; R858-859.7 ; Public aspects of medicine ; RA1-1270
Subject code	150
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Polyaromatic Bis (indolyl)methane Derivatives with Antiproliferative and Antiparasitic Activity

Raquel C. R. Gonçalves / Pablo Peñalver / Susana P. G. Costa / Juan C. Morales / Maria Manuela M. Raposo

Molecules, Vol 28, Iss 23, p

2023 Volume 7728

Abstract: Bis (indolyl)methanes (BIMs) are a class of compounds that have been recognized as an important core in the design of drugs with important pharmacological properties, such as promising anticancer and antiparasitic activities. Here, we explored the ... ...

Abstract	Bis (indolyl)methanes (BIMs) are a class of compounds that have been recognized as an important core in the design of drugs with important pharmacological properties, such as promising anticancer and antiparasitic activities. Here, we explored the biological activity of the BIM core functionalized with different (hetero)aromatic moieties. We synthesized substituted BIM derivatives with triphenylamine, N,N -dimethyl-1-naphthylamine and 8-hydroxylquinolyl groups, studied their photophysical properties and evaluated their in vitro antiproliferative and antiparasitic activities. The triphenylamine BIM derivative 2a displayed an IC 50 of 3.21, 3.30 and 3.93 μM against Trypanosoma brucei , Leishmania major and HT-29 cancer cell line, respectively. The selectivity index demonstrated that compound 2a was up to eight-fold more active against the parasites and HT-29 than against the healthy cell line MRC-5. Fluorescence microscopy studies with MRC-5 cells and T. brucei parasites incubated with derivative 2a indicate that the compound seems to accumulate in the cell’s mitochondria and in the parasite’s nucleus. In conclusion, the BIM scaffold functionalized with the triphenylamine moiety proved to be the most promising antiparasitic and anticancer agent of this series.
Keywords	African trypanosomiasis ; antiproliferative agent ; antiprotozoal agent ; bis (indolyl)methane derivatives ; leishmaniasis ; Organic chemistry ; QD241-441
Subject code	540
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Solid waste management system for small island developing states

J. Weekes / J. Musa Wasil / K. Malave Llamas / C. Morales Agrinzoni

Global Journal of Environmental Science and Management, Vol 7, Iss 2, Pp 259-

2021 Volume 272

Abstract: BACKGROUND AND OBJECTIVES: Solid waste management which entails the generation, storage, collection, transportation, processing, treatment and disposal of waste products is regarded as a challenge to many countries worldwide. The focus and methods vary ... ...

Abstract	BACKGROUND AND OBJECTIVES: Solid waste management which entails the generation, storage, collection, transportation, processing, treatment and disposal of waste products is regarded as a challenge to many countries worldwide. The focus and methods vary in all territories given the wide range of factors which influence waste management. Small Island Developing States face unique challenges which are influenced by their peculiar physical, economic, social, political and institutional characteristic. Consequently, they require a solid waste management system tailored to their unique requirements.METHODS: Qualitative and quantitative data were gathered between February and November 2019 from various primary and secondary sources using the following instruments and techniques: literature review of reports, news articles, legislation, journals and case studies; on-site observations; and administering questionnaires in the study area in October 2019. The study area comprised 3 communities which were representative of the waste management district, and were selected using the purposive sampling method, while the sample size of 0.3% of the households in the study area was selected randomly by administering questionnaires to anonymous respondents in arbitrary households in the communities. Using descriptive methods, data was tallied and grouped, then the content analysed to determine patterns, to answer questions to the problems and to determine relationships and themes. Findings were summarised, simplified and presented in formats such as graphs and tables and written descriptive accounts. FINDINGS: Solid waste management affects all countries irrespective of their level of development. The focal point varies across societies. Small Island Developing States have a unique challenge posed by their particular characteristics. Given that each territory has a peculiar mix of factors, any solid waste management system derived must be exclusive to each. There is no single, ideal system which can be proposed. Whatever the system ...
Keywords	environmental education ; small island developing states (sids) ; solid waste management (swm) ; sustainability ; waste reduction ; Environmental sciences ; GE1-350
Subject code	710
Language	English
Publishing date	2021-04-01T00:00:00Z
Publisher	GJESM Publisher
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Molecular Pathogenesis and Peripheral Monitoring of Adult Fragile X-Associated Syndromes

Luis M. Valor / Jorge C. Morales / Irati Hervás-Corpión / Rosario Marín

International Journal of Molecular Sciences, Vol 22, Iss 8368, p

2021 Volume 8368

Abstract: Abnormal trinucleotide expansions cause rare disorders that compromise quality of life and, in some cases, lifespan. In particular, the expansions of the CGG-repeats stretch at the 5’-UTR of the Fragile X Mental Retardation 1 ( FMR1 ) gene have ... ...

Abstract	Abnormal trinucleotide expansions cause rare disorders that compromise quality of life and, in some cases, lifespan. In particular, the expansions of the CGG-repeats stretch at the 5’-UTR of the Fragile X Mental Retardation 1 ( FMR1 ) gene have pleiotropic effects that lead to a variety of Fragile X-associated syndromes: the neurodevelopmental Fragile X syndrome (FXS) in children, the late-onset neurodegenerative disorder Fragile X-associated tremor-ataxia syndrome (FXTAS) that mainly affects adult men, the Fragile X-associated primary ovarian insufficiency (FXPOI) in adult women, and a variety of psychiatric and affective disorders that are under the term of Fragile X-associated neuropsychiatric disorders (FXAND). In this review, we will describe the pathological mechanisms of the adult “gain-of-function” syndromes that are mainly caused by the toxic actions of CGG RNA and FMRpolyG peptide. There have been intensive attempts to identify reliable peripheral biomarkers to assess disease progression and onset of specific pathological traits. Mitochondrial dysfunction, altered miRNA expression, endocrine system failure, and impairment of the GABAergic transmission are some of the affectations that are susceptible to be tracked using peripheral blood for monitoring of the motor, cognitive, psychiatric and reproductive impairment of the CGG-expansion carriers. We provided some illustrative examples from our own cohort. Understanding the association between molecular pathogenesis and biomarkers dynamics will improve effective prognosis and clinical management of CGG-expansion carriers.
Keywords	FXTAS ; FXPOI ; FXAND ; premutation ; blood ; biomarker ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Múltiples nódulos queloideos en paciente mujer de mediana edad

M.J. Hernández San Martín / V. Kaplan Zapata / C. Morales Huber

Actas Dermo-Sifiliográficas, Vol 112, Iss 10, Pp 917-

2021 Volume 918

Keywords	Dermatology ; RL1-803 ; Internal medicine ; RC31-1245
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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