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  1. Article ; Online: Management of Alcohol-Related Liver Disease and Its Complications.

    Cabezas, Joaquín

    Clinical drug investigation

    2022  Volume 42, Issue Suppl 1, Page(s) 47–53

    Abstract: Alcohol-related liver disease (ALD) is a major healthcare/economic burden and one of the leading causes of liver transplantation. New epidemiological studies that detail the course of the disease are needed since, despite its high prevalence, it is still ...

    Abstract Alcohol-related liver disease (ALD) is a major healthcare/economic burden and one of the leading causes of liver transplantation. New epidemiological studies that detail the course of the disease are needed since, despite its high prevalence, it is still a stigmatised condition with underlying pathology. Alcoholic hepatitis, as the highest expression of ALD, has high morbidity. Current treatments have suboptimal results with the exception of liver transplantation. Epidemiological studies must also be developed to improve prevention and implement early diagnosis policies. It is essential to develop multidisciplinary health models that allow the liver transplantation candidate to be approached in a holistic way, both for indication and follow up. The implementation of alcohol consumption biomarkers (ethyl glucuronide, phosphatidylethanol) can assist in diagnosing and supporting recovery. There are several initiatives with new therapies that must be validated to establish their effectiveness and indication.
    MeSH term(s) Alcohol Drinking ; Biomarkers ; Humans ; Liver Diseases, Alcoholic/diagnosis ; Liver Diseases, Alcoholic/etiology ; Liver Diseases, Alcoholic/therapy ; Liver Transplantation/adverse effects
    Chemical Substances Biomarkers
    Language English
    Publishing date 2022-04-25
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 1220136-4
    ISSN 1179-1918 ; 0114-2402 ; 1173-2563
    ISSN (online) 1179-1918
    ISSN 0114-2402 ; 1173-2563
    DOI 10.1007/s40261-022-01143-9
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  2. Article: Letter to the Editor in response to the recently published article "Roncero C, Buch B, Martin-Sanchez AM, et al. Prevalence of hepatitis C virus infection in patients with chronic mental disorders: the relevance of dual diagnosis. Gastroenterol Hepatol. 2022".

    Cuadrado, Antonio / Cabezas, Joaquin / Crespo, Javier

    Gastroenterologia y hepatologia

    2022  Volume 46, Issue 3, Page(s) 214

    MeSH term(s) Humans ; Hepacivirus ; Prevalence ; Diagnosis, Dual (Psychiatry) ; Hepatitis C ; Mental Disorders/complications ; Substance-Related Disorders
    Language Spanish
    Publishing date 2022-08-11
    Publishing country Spain
    Document type Letter ; Comment
    ZDB-ID 632502-6
    ISSN 0210-5705
    ISSN 0210-5705
    DOI 10.1016/j.gastrohep.2022.07.007
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  3. Article ; Online: The path to successful hepatitis C elimination in Spain.

    Crespo, Javier / Cabezas, Joaquín / Calleja, José Luis / Buti, María / Lazarus, Jeffrey V

    Nature reviews. Gastroenterology & hepatology

    2023  Volume 20, Issue 11, Page(s) 689–690

    MeSH term(s) Humans ; Spain/epidemiology ; Hepatitis C/drug therapy ; Hepatitis C/epidemiology ; Hepatitis C/prevention & control ; Hepacivirus
    Language English
    Publishing date 2023-07-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2493722-8
    ISSN 1759-5053 ; 1759-5045
    ISSN (online) 1759-5053
    ISSN 1759-5045
    DOI 10.1038/s41575-023-00813-z
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  4. Article: Telemedicine, time to change the paradigm of hepatitis C management: improve access and reduce costs In reference to: Chronic viral hepatitis C micro-elimination program using telemedicine. The Mexican experience, by Pérez Hernández et al.

    Cabezas, Joaquín / Llerena, Susana / Crespo, Javier

    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

    2021  Volume 113, Issue 8, Page(s) 623–624

    Abstract: Hepatitis C (HCV) management has dramatically changed with the advent of direct-acting antivirals. Their high efficacy and safety are changing the paradigm of detection and treatment of patients with an active HCV infection. Following the latest ... ...

    Abstract Hepatitis C (HCV) management has dramatically changed with the advent of direct-acting antivirals. Their high efficacy and safety are changing the paradigm of detection and treatment of patients with an active HCV infection. Following the latest guidelines, the path to elimination of hepatitis C will be achieved by simplifying management.
    MeSH term(s) Antiviral Agents/therapeutic use ; Hepacivirus ; Hepatitis C/drug therapy ; Hepatitis C, Chronic/drug therapy ; Humans ; Telemedicine
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2021-02-08
    Publishing country Spain
    Document type Letter
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
    DOI 10.17235/reed.2021.7809/2021
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  5. Article ; Online: HCV detection is possible during SARS CoV-2 testing; and throughout COVID-19 vaccination?

    Crespo, Javier / Díaz-González, Álvaro / Cabezas, Joaquín

    Journal of hepatology

    2021  Volume 75, Issue 2, Page(s) 486–487

    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Hepatitis C/diagnosis ; Humans ; Italy ; SARS-CoV-2 ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-05-07
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2021.04.043
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  6. Article ; Online: Anti-epileptic drugs and hepatitis C therapy: Real-world experience.

    Marcos-Fosch, Cristina / Cabezas, Joaquín / Crespo, Javier / Buti, Maria

    Journal of hepatology

    2021  Volume 75, Issue 4, Page(s) 984–985

    MeSH term(s) Adult ; Anticonvulsants/adverse effects ; Anticonvulsants/therapeutic use ; Antiviral Agents/adverse effects ; Antiviral Agents/therapeutic use ; Drug Interactions/physiology ; Epilepsy/drug therapy ; Female ; Hepatitis C/drug therapy ; Humans ; Male ; Middle Aged
    Chemical Substances Anticonvulsants ; Antiviral Agents
    Language English
    Publishing date 2021-06-11
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2021.05.040
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  7. Article ; Online: A call for the comprehensive diagnosis of viral hepatitis as a key step towards its elimination.

    Crespo, Javier / Calleja, José Luis / Cabezas, Joaquín / García, Federico / Aguilera, Antonio / Jorquera, Francisco / Lazarus, Jeffrey V

    Liver international : official journal of the International Association for the Study of the Liver

    2023  Volume 43, Issue 5, Page(s) 1145–1147

    MeSH term(s) Humans ; HIV Infections ; Hepatitis, Viral, Human/diagnosis
    Language English
    Publishing date 2023-03-08
    Publishing country United States
    Document type Letter
    ZDB-ID 2102783-3
    ISSN 1478-3231 ; 1478-3223
    ISSN (online) 1478-3231
    ISSN 1478-3223
    DOI 10.1111/liv.15529
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    Zs.A 1632: Show issues Location:
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  8. Article ; Online: Barriers and advocacy needs for hepatitis C services in prisons: Informing the prisons hepatitis C advocacy toolkit.

    Walker, Shelley J / Shrestha, Lok B / Lloyd, Andrew R / Dawson, Olivia / Sheehan, Yumi / Sheehan, Julia / Maduka, Nonso B C / Cabezas, Joaquin / Akiyama, Matthew J / Kronfli, Nadine

    The International journal on drug policy

    2024  Volume 126, Page(s) 104386

    Abstract: Background: Carceral settings are a key focus of the 2030 WHO global hepatitis C virus (HCV) elimination goals. Despite this, access to HCV testing and treatment services in prisons remains low globally, limiting opportunities to achieve these goals. ... ...

    Abstract Background: Carceral settings are a key focus of the 2030 WHO global hepatitis C virus (HCV) elimination goals. Despite this, access to HCV testing and treatment services in prisons remains low globally, limiting opportunities to achieve these goals. Advocacy efforts are needed to address service inequities and mobilise support for enhanced HCV programs in prisons globally. INHSU Prisons, a special interest group of the International Network on Health and Hepatitis in Substance Users (INHSU) is developing a Prisons HCV Advocacy Toolkit to address this need. Here we present findings of a mixed study to inform the development of the Toolkit.
    Methods: The aim of this study was to inform the development of the Toolkit, including understanding barriers for scaling up prison-based HCV services globally and advocacy needs to address these. An online survey (n = 181) and in-depth interviews (n = 25) were conducted with key stakeholders from countries of different economic status globally. Quantitative data were statistically analysed using R Studio and qualitative data were analysed thematically. The data sets were merged using a convergent design.
    Results: Key barriers for enhanced prison-based HCV services included lack of political will and action, lack of prison-based healthcare resources, and poor awareness about HCV and the importance of prison-based HCV services. These findings underscore how advocacy efforts are needed to motivate policymakers to prioritise HCV healthcare in prisons and ensure funds are available for services (including diagnostic tools and treatment, healthcare teams to implement services, and systems to measure their success). Advocacy resources to raise the awareness of policy makers, people working in the prison sector, and incarcerated populations were also identified as key to increasing HCV service uptake.
    Conclusion: The Toolkit has the potential to support advocacy efforts for reaching HCV elimination targets. By understanding the advocacy needs of potential Toolkit end-users, the findings can inform its development and increase its accessibility, acceptability, and uptake for a globally diverse audience.
    MeSH term(s) Humans ; Hepatitis C/epidemiology ; Prisons/organization & administration ; Health Services Accessibility/organization & administration ; Patient Advocacy ; Surveys and Questionnaires ; Prisoners ; Global Health
    Language English
    Publishing date 2024-03-15
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2010000-0
    ISSN 1873-4758 ; 0955-3959
    ISSN (online) 1873-4758
    ISSN 0955-3959
    DOI 10.1016/j.drugpo.2024.104386
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  9. Article ; Online: Alcoholic liver disease: New UK alcohol guidelines and Dry January: enough to give up boozing?

    Cabezas, Joaquin / Bataller, Ramon

    Nature reviews. Gastroenterology & hepatology

    2016  Volume 13, Issue 4, Page(s) 191–192

    MeSH term(s) Alcohol Abstinence ; Alcohol Drinking/prevention & control ; Health Policy ; Health Promotion/methods ; Humans ; Liver Diseases, Alcoholic/prevention & control ; United Kingdom
    Language English
    Publishing date 2016-04
    Publishing country England
    Document type News ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2493722-8
    ISSN 1759-5053 ; 1759-5045
    ISSN (online) 1759-5053
    ISSN 1759-5045
    DOI 10.1038/nrgastro.2016.39
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  10. Article ; Online: Alcoholic hepatitis: should we combine old drugs for better results?

    Cabezas, Joaquin / Bataller, Ramon

    Hepatology international

    2016  Volume 10, Issue 6, Page(s) 851–853

    MeSH term(s) Acetylcysteine/therapeutic use ; Antioxidants/therapeutic use ; Clinical Trials as Topic ; Disease Management ; Drug Therapy, Combination/methods ; Hepatitis, Alcoholic/drug therapy ; Humans ; Prednisolone/therapeutic use ; S-Adenosylmethionine/therapeutic use ; Treatment Outcome
    Chemical Substances Antioxidants ; S-Adenosylmethionine (7LP2MPO46S) ; Prednisolone (9PHQ9Y1OLM) ; Acetylcysteine (WYQ7N0BPYC)
    Language English
    Publishing date 2016-09-15
    Publishing country United States
    Document type Editorial
    ZDB-ID 2270316-0
    ISSN 1936-0541 ; 1936-0533
    ISSN (online) 1936-0541
    ISSN 1936-0533
    DOI 10.1007/s12072-016-9768-8
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