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  1. Article ; Online: Reconstruction of a large upper arm defect with muscle sparing latissimus dorsi.

    Cadenelli, Pierfrancesco / Bordoni, Daniele / Ornelli, Matteo / Radaelli, Stefano

    BMJ case reports

    2016  Volume 2016

    Abstract: Reconstruction of large soft tissue defects in the upper arm represents a challenge for the reconstructive surgeon. The latissimus dorsi flap is widely used and preferred for this latter type of reconstruction due to its reliability and versatility, ... ...

    Abstract Reconstruction of large soft tissue defects in the upper arm represents a challenge for the reconstructive surgeon. The latissimus dorsi flap is widely used and preferred for this latter type of reconstruction due to its reliability and versatility, although sacrificing the entire muscle can lead to higher incidences of postoperative seroma and functional disability. The recent introduction of the perforator-based flap concept has led to an evolution in upper extremity reconstruction by significantly reducing donor-site morbidity and simultaneously ensuring optimal soft tissues coverage. We report a case of a large soft tissue defect of the posterolateral part of the upper arm, consequent to a sarcoma resection, in which a muscle-sparing latissimus dorsi technique was used to obtain total soft tissue coverage. A 2-year follow-up showed a satisfactory functional result and no evidence of recurrence.
    MeSH term(s) Aged ; Arm/surgery ; Humans ; Male ; Reconstructive Surgical Procedures/methods ; Sarcoma/surgery ; Soft Tissue Neoplasms/surgery ; Superficial Back Muscles/transplantation ; Surgical Flaps ; Treatment Outcome
    Language English
    Publishing date 2016-08-23
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2016-216684
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Proximally Based Anterolateral-Thigh (ALT) Flap for Knee Reconstruction: An Advancement Propeller Perforator Flap.

    Cadenelli, Pierfrancesco / Bordoni, Daniele / Radaelli, Stefano / Marchesi, Andrea

    Aesthetic plastic surgery

    2015  Volume 39, Issue 5, Page(s) 752–756

    Abstract: Background: Adequate coverage of the knee region is often challenging for plastic and orthopedic surgeons. In the last decade, among several reconstructive techniques, local perforator flaps have become useful reconstructive units. After a wide ... ...

    Abstract Background: Adequate coverage of the knee region is often challenging for plastic and orthopedic surgeons. In the last decade, among several reconstructive techniques, local perforator flaps have become useful reconstructive units. After a wide resection for soft-tissue sarcoma, the knee vascular web may be reasonably damaged and, consequently, perforator flaps based on a local pedicle [such as the distally based anterolateral thigh (ALT) flap] are not reliable. Thus, we harvested a proximally based ALT for knee coverage.
    Methods: A 52-year-old man underwent local radiation therapy and a wide resection of a soft-tissue sarcoma on the anterior-lateral aspect of the left knee, which resulted in a 15 × 10 cm defect. The defect was covered with a proximally based ALT, through an advancement and propeller relocation of its skin paddle.
    Results: All margins were tumor free. After 5 days, the donor site was closed primarily because of edema. Neither necrosis of the flap nor dehiscence of the wound was detected. No local relapses were detected at 6-month follow-up.
    Conclusions: In case of soft-tissue defects of the knee region, with likely involvement of the local vascular web, a local perforator solution is the advancement and propeller proximally based ALT flap.
    Level of evidence v: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    MeSH term(s) Humans ; Knee ; Male ; Middle Aged ; Myocutaneous Flap/blood supply ; Myocutaneous Flap/transplantation ; Perforator Flap/blood supply ; Perforator Flap/transplantation ; Reconstructive Surgical Procedures/methods ; Recovery of Function ; Risk Assessment ; Sarcoma/pathology ; Sarcoma/surgery ; Skin Neoplasms/pathology ; Skin Neoplasms/surgery ; Thigh/surgery ; Tissue and Organ Harvesting ; Treatment Outcome ; Wound Healing/physiology
    Language English
    Publishing date 2015-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 532791-x
    ISSN 1432-5241 ; 0364-216X
    ISSN (online) 1432-5241
    ISSN 0364-216X
    DOI 10.1007/s00266-015-0536-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The axillary flap in oncoplastic resection of breast cancers located in the upper-outer quadrants

    Bordoni, D. / Cadenelli, P. / Ornelli, M. / Falco, G. / Accurso, A. / Gloria, A. / Maietta, S. / Rocco, N. / Magalotti, C.

    A new surgical technique

    2019  

    Abstract: Art. 21, 7 S. ... Background: The combination of breast conserving surgery (BCS) with plastic surgery techniques has provided a useful surgical tool matching the radicality of the oncological excision with the preservation of breast cosmesis. Even though ... ...

    Abstract Art. 21, 7 S.

    Background: The combination of breast conserving surgery (BCS) with plastic surgery techniques has provided a useful surgical tool matching the radicality of the oncological excision with the preservation of breast cosmesis. Even though BCS represents a good option for surgical treatment of tumors located in these quadrants, wide excisions often necessitate breast reshaping in order to avoid nipple areola complex (NAC) displacement and skin retraction. We present a new surgical technique to repair upper-outer quadrants' defects following breast cancer excision using dermo-glandular flaps and an axillary adipo-fascial flap. Methods: During the period from January 2014 to December 2015, 168 patients with an upper-outer quadrant's breast cancer have been treated in our Department. 83 women have been treated with the described oncoplastic technique and immediate contra-lateral symmetrisation and 85 women underwent standard BCS. We present surgical, oncological and cosmetic outcomes comparing our results with standard BCS. Results: At a mean follow-up of 27 months loco-regional recurrences in the two groups were comparable. Short-term complication rates were comparable between the two groups. Re-intervention rates for positive margins were significantly higher in the standard BCS group. The overall satisfaction with cosmetic outcome both assessed by the patient and the surgeon was significantly higher in the oncoplastic group. Conclusions: The proposed oncoplastic technique represents a safe and effective solution for reshaping that follows upper-outer breast cancer wide excision, achieving comparable complication rates, lower re-intervention rates for positive margins and better cosmetic results when compared with standard BCS.

    18
    Keywords 617
    Subject code 616
    Language English
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: The axillary flap in oncoplastic resection of breast cancers located in the upper-outer quadrants: a new surgical technique.

    Bordoni, Daniele / Cadenelli, Pierfrancesco / Ornelli, Matteo / Falco, Giuseppe / Accurso, Antonello / Gloria, Antonio / Maietta, Saverio / Rocco, Nicola / Magalotti, Cesare

    BMC surgery

    2019  Volume 18, Issue Suppl 1, Page(s) 21

    Abstract: Background: The combination of breast conserving surgery (BCS) with plastic surgery techniques has provided a useful surgical tool matching the radicality of the oncological excision with the preservation of breast cosmesis. Even though BCS represents a ...

    Abstract Background: The combination of breast conserving surgery (BCS) with plastic surgery techniques has provided a useful surgical tool matching the radicality of the oncological excision with the preservation of breast cosmesis. Even though BCS represents a good option for surgical treatment of tumors located in these quadrants, wide excisions often necessitate breast reshaping in order to avoid nipple areola complex (NAC) displacement and skin retraction. We present a new surgical technique to repair upper-outer quadrants' defects following breast cancer excision using dermo-glandular flaps and an axillary adipo-fascial flap.
    Methods: During the period from January 2014 to December 2015, 168 patients with an upper-outer quadrant's breast cancer have been treated in our Department. 83 women have been treated with the described oncoplastic technique and immediate contra-lateral symmetrisation and 85 women underwent standard BCS. We present surgical, oncological and cosmetic outcomes comparing our results with standard BCS.
    Results: At a mean follow-up of 27 months loco-regional recurrences in the two groups were comparable. Short-term complication rates were comparable between the two groups. Re-intervention rates for positive margins were significantly higher in the standard BCS group. The overall satisfaction with cosmetic outcome both assessed by the patient and the surgeon was significantly higher in the oncoplastic group.
    Conclusions: The proposed oncoplastic technique represents a safe and effective solution for reshaping that follows upper-outer breast cancer wide excision, achieving comparable complication rates, lower re-intervention rates for positive margins and better cosmetic results when compared with standard BCS.
    MeSH term(s) Adult ; Aged ; Axilla ; Breast Neoplasms/surgery ; Female ; Humans ; Mammaplasty/methods ; Margins of Excision ; Mastectomy, Segmental/methods ; Middle Aged ; Neoplasm Recurrence, Local/surgery ; Retrospective Studies ; Surgical Flaps
    Language English
    Publishing date 2019-04-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050442-1
    ISSN 1471-2482 ; 1471-2482
    ISSN (online) 1471-2482
    ISSN 1471-2482
    DOI 10.1186/s12893-018-0467-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Serratus Anterior Fascia Flap Versus Muscular Flap for Expander Coverage in Two-stage Breast Reconstruction Following Mastectomy: Early Post-operative Outcomes.

    Bordoni, Daniele / Cadenelli, Pierfrancesco / Rocco, Nicola / Tessone, Ariel / Falco, Giuseppe / Magalotti, Cesare

    Aesthetic plastic surgery

    2016  Volume 41, Issue 1, Page(s) 26–30

    Abstract: Introduction: The demand for reconstructive breast surgery after mastectomy is increasing among women and the two-stage option remains the most commonly performed technique. We conducted a self-controlled prospective clinical trial comparing the use of ... ...

    Abstract Introduction: The demand for reconstructive breast surgery after mastectomy is increasing among women and the two-stage option remains the most commonly performed technique. We conducted a self-controlled prospective clinical trial comparing the use of the serratus anterior fascia with the serratus anterior detached fibers to cover the inferolateral aspect of the expander in immediate two-stage breast reconstruction following conservative mastectomies as oncological or risk-reducing procedures.
    Patients and methods: We analyzed the surgical outcome of 29 bilateral mastectomies and immediate reconstruction with the positioning of a tissue expander in a pocket beneath the pectoralis major and serratus anterior muscle on one side and in a pocket beneath the pectoralis major and a serratus anterior fascia flap on the other side. We considered all complications presenting in the first month after surgery and patient-reported early post-operative pain.
    Results: Complication rates in the two groups did not significantly differ (p = 0.237). The total amount of drainage and the time of drainage permanence were significantly lower for the subfascial group (p < 0.05). Patient-reported early post-operative pain was significantly different between the two groups both at 24 h (p < 0.05) and at 5 days (p < 0.05) with significantly lower pain scores reported by the patients in the subfascial group.
    Discussion: Our self-controlled prospective trial demonstrated an advantage in performing an implant-based two-stage breast reconstruction using a serratus anterior fascia flap when compared with the serratus muscle fibers use for inferolateral implant coverage following mastectomy. The use of the anterior serratus fascia flap for inferolateral implant coverage in two-stage breast reconstructions following mastectomy could be considered as a safe and effective technique, presenting lower morbidity for the patient when compared with the serratus muscle fibers use and lower costs when compared with biological and synthetic meshes use, achieving good outcomes in terms of post-operative complications and women's quality of life and satisfaction levels.
    Level of evidence iii: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    MeSH term(s) Adult ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Cohort Studies ; Esthetics ; Fascia/blood supply ; Fascia/transplantation ; Female ; Graft Rejection ; Graft Survival ; Humans ; Mammaplasty/adverse effects ; Mammaplasty/methods ; Mastectomy/methods ; Middle Aged ; Myocutaneous Flap/blood supply ; Myocutaneous Flap/transplantation ; Pain, Postoperative/physiopathology ; Patient Satisfaction/statistics & numerical data ; Postoperative Complications/epidemiology ; Postoperative Complications/physiopathology ; Postoperative Period ; Prospective Studies ; Risk Assessment ; Tissue Expansion/methods ; Wound Healing/physiology
    Language English
    Publishing date 2016-12-28
    Publishing country United States
    Document type Comparative Study ; Evaluation Study ; Journal Article
    ZDB-ID 532791-x
    ISSN 1432-5241 ; 0364-216X
    ISSN (online) 1432-5241
    ISSN 0364-216X
    DOI 10.1007/s00266-016-0770-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Autologous fat tissue grafting improves pulmonary healing after laser metastasectomy.

    Furia, Simone / Cadenelli, Pierfrancesco / Andriani, Francesca / Scanagatta, Paolo / Duranti, Leonardo / Spano, Andrea / Galeone, Carlotta / Porcu, Luca / Pastorino, Ugo

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2017  

    Abstract: Background: Extensive clinical experience has demonstrated the potential usefulness of autologous fat tissue (AFT) graft in tissue reconstruction, repair or regeneration. In the present study, we evaluated the feasibility and safety of AFT in the repair ...

    Abstract Background: Extensive clinical experience has demonstrated the potential usefulness of autologous fat tissue (AFT) graft in tissue reconstruction, repair or regeneration. In the present study, we evaluated the feasibility and safety of AFT in the repair of surgically injured lung surface.
    Methods: Eighty consecutive procedures of pulmonary metastasectomy by laser precision resection, were performed in 66 patients between March 2010 and December 2012. In the first 20 procedures, AFT graft was applied on the wounded pulmonary surface without closure of parenchymal surface. The following 40 procedures were carried on without AFT (20 leaving the resection margins open and 20 closing the resection margins with a running suture). In the remaining 20 procedures, AFT was applied and the resection margins closed. The efficacy of this technique was evaluated by comparing the AFT group with the non-AFT group, with respect to prolonged alveolar air leakage (PAAL), time to drain removal, length of hospital stay, and patient survival at four years.
    Results: The occurrence of PAAL was lower in the AFT group as compared to non-AFT group (17.5% versus 42.5%, p = 0.027), and median time to drain removal shorter (4 versus 6 days respectively, p = 0.016). Overall 4-year survival was 70% for AFT group, and 59% for non-AFT group (p = 0.34).
    Conclusions: This prospective cohort observational study demonstrated the feasibility and safety of AFT pulmonary grafting after laser metastasectomy. AFT graft improved pulmonary healing, by reducing the incidence and severity of PAAL. Moreover, there was no evidence of tumor promotion in the metastatic setting, with a similar overall survival at 4 years.
    Language English
    Publishing date 2017-10-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2017.09.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Extreme oncoplastic breast surgery: A case report.

    Bordoni, Daniele / Cadenelli, Pierfrancesco / Falco, Giuseppe / Rocco, Nicola / Manna, Paola / Tessone, Ariel / Ornelli, Matteo / Magalotti, Cesare

    International journal of surgery case reports

    2016  Volume 28, Page(s) 182–187

    Abstract: Introduction: So called "extreme oncoplastic surgery" is emerging as a new promising concept in breast cancer surgery allowing successful breast conservation in selected patients with multicentric tumors.: Presentation of case: We report the case of ... ...

    Abstract Introduction: So called "extreme oncoplastic surgery" is emerging as a new promising concept in breast cancer surgery allowing successful breast conservation in selected patients with multicentric tumors.
    Presentation of case: We report the case of a 48-year-old woman presenting with a multicentric breast cancer and successfully treated with an oncoplastic technique consisting in three radical lumpectomies followed by breast reshaping and simultaneous contralateral symmetrization.
    Discussion: According to our experience, oncoplastic conserving breast surgery could represent a better option than the combination of mastectomy, reconstruction and radiation therapy, in terms of quality of life for selected patients affected by multicentric breast cancer.
    Conclusion: The surgical treatment for multicentric breast cancers remains controversial even though emerging evidences show good oncological and aesthetic outcomes following oncoplastic conserving breast surgery.
    Language English
    Publishing date 2016-09-28
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2016.09.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Primary angiosarcoma of the breast.

    Bordoni, Daniele / Bolletta, Elisa / Falco, Giuseppe / Cadenelli, Pierfrancesco / Rocco, Nicola / Tessone, Ariel / Guarino, Stefania / Accurso, Antonello / Amato, Bruno / Magalotti, Cesare

    International journal of surgery case reports

    2016  Volume 20S, Page(s) 12–15

    Abstract: Primary angiosarcoma (AS) of the breast is a rare neoplasia that is not related to radiation exposure. It represents less than 0.05% of all malignant breast tumors. This lesion is characterized by aggressive patterns and poor prognosis and by the absence ...

    Abstract Primary angiosarcoma (AS) of the breast is a rare neoplasia that is not related to radiation exposure. It represents less than 0.05% of all malignant breast tumors. This lesion is characterized by aggressive patterns and poor prognosis and by the absence of typical features at radiologic examination. Currently there are not evidence-based guidelines regarding surgical and adjuvant treatment for this tumor even though wide surgical resection followed by chemo- radiotherapy appears to improve both disease free survival and overall survival. The aim of this study was to analyze the available series of AS patients suggesting the most reliable treatment options for this rare neoplasia.
    Language English
    Publishing date 2016-02-03
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2016.02.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Electrochemotherapy: a good idea in recurrent basal cell carcinoma treatment.

    Ruggeri, Roberta / Maurichi, Andrea / Tinti, Maria Carla / Cadenelli, Pierfrancesco / Patuzzo, Roberto / Gallino, Gianfrancesco / Santinami, Mario

    Melanoma management

    2015  Volume 2, Issue 1, Page(s) 27–31

    Abstract: Basal cell carcinoma (BCC) is the most common skin cancer in Caucasian population. Surgical excision is the gold standard treatment for BCC. Secondary surgical approach in patients presenting surgical scars after multiple surgical excisions or submitted ... ...

    Abstract Basal cell carcinoma (BCC) is the most common skin cancer in Caucasian population. Surgical excision is the gold standard treatment for BCC. Secondary surgical approach in patients presenting surgical scars after multiple surgical excisions or submitted to radiotherapy without obtaining a safe clearance margin, should be avoided. In recent years the use of electrochemotherapy (ECT) in head and neck cancers using intravenous bleomycin was specifically addressed and BCC resulted to be among tumors with the best response to ECT. We report a case of a recurrent nasal BCC treated with ECT with a complete regression of lesions after 8 weeks and a disease free period of 7 months. ECT is a good palliative treatment not affecting survival rate but improving quality of life in patients.
    Language English
    Publishing date 2015-02-25
    Publishing country England
    Document type Case Reports
    ZDB-ID 2786852-7
    ISSN 2045-0893 ; 2045-0893
    ISSN (online) 2045-0893
    ISSN 2045-0893
    DOI 10.2217/mmt.14.28
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Extra-projected implants as an alternative surgical model for breast reconstruction. Implantation strategy and early results.

    Nava, Maurizio B / Spano, Andrea / Cadenelli, Pierfrancesco / Colombetti, Anna / Menozzi, Andrea / Pennati, Angela / Catanuto, Giuseppe

    Breast (Edinburgh, Scotland)

    2008  Volume 17, Issue 4, Page(s) 361–366

    Abstract: The present study reports on patients who underwent breast reconstructions with extra-projection implants. Two-hundred and thirty-four women were treated for 238 breast reconstructions irrespectively of breast shape and size. In this series we aimed to ... ...

    Abstract The present study reports on patients who underwent breast reconstructions with extra-projection implants. Two-hundred and thirty-four women were treated for 238 breast reconstructions irrespectively of breast shape and size. In this series we aimed to reconstruct for all women a bilateral cosmetic medium-size breast (between 400 and 500 cc), highly projected, with a little to moderate ptosis rather then a ptotic one exactly matching the contra-lateral. This is demonstrated by volume of implants that ranged from 397 cc for ladies with small breast who received an augmentation, to 533 cc for those who side required a reduction surgery. Eighty-six percent of patients received contra-lateral procedures. Complication rate was 8.4% and 66% of reconstructions were rated as good in the patients' opinion. Extra-projection implants, coupled with contra-lateral breast surgery, provide a good aesthetic outcome and avoid myocutaneous flaps only on the basis of breast size and shape.
    MeSH term(s) Adult ; Aged ; Breast Implantation ; Breast Implants ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Cohort Studies ; Female ; Humans ; Middle Aged ; Patient Satisfaction ; Prosthesis Design ; Surgical Flaps ; Treatment Outcome
    Language English
    Publishing date 2008-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1143210-x
    ISSN 1532-3080 ; 0960-9776
    ISSN (online) 1532-3080
    ISSN 0960-9776
    DOI 10.1016/j.breast.2008.01.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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