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  1. Article ; Online: Adalimumab-induced aseptic meningitis in a patient with rheumatoid arthritis.

    Berti, Pier / Schwarz, Andreas / Pirillo, Vania / Lanzinger, Siglinde / Kluge, Reinhard / Cagini, Angelo / Karner, Martin / Zampogna, Giuseppe / Dejaco, Christian

    Joint bone spine

    2022  Volume 89, Issue 4, Page(s) 105356

    MeSH term(s) Adalimumab/adverse effects ; Antirheumatic Agents/adverse effects ; Arthritis, Rheumatoid/drug therapy ; Humans ; Meningitis, Aseptic/chemically induced ; Meningitis, Aseptic/diagnosis ; Meningitis, Aseptic/drug therapy
    Chemical Substances Antirheumatic Agents ; Adalimumab (FYS6T7F842)
    Language English
    Publishing date 2022-02-12
    Publishing country France
    Document type Letter
    ZDB-ID 2020487-5
    ISSN 1778-7254 ; 1297-319X
    ISSN (online) 1778-7254
    ISSN 1297-319X
    DOI 10.1016/j.jbspin.2022.105356
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Seltene Raumforderung der Brust.

    Ruiu, A / Stuppner, S / Bertelli, G / Armatura, G / Luethy, M / Damiani, D / Cagini, A / Steinkasserer, M / Lusso, M R / Ferro, F

    Der Radiologe

    2021  Volume 61, Issue 11, Page(s) 1020–1023

    Title translation Rare mass in the breast.
    MeSH term(s) Breast/diagnostic imaging ; Breast Neoplasms/diagnostic imaging ; Female ; Humans
    Language German
    Publishing date 2021-07-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 505520-9
    ISSN 1432-2102 ; 0033-832X
    ISSN (online) 1432-2102
    ISSN 0033-832X
    DOI 10.1007/s00117-021-00888-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Seltener Weichteiltumor der Brusthaut.

    Ruiu, A / Stuppner, S / Barillari, M / Pedrinolla, B / Casalboni, C / Eisendle, K / Pichler, M / Hanspeter, E / Cagini, A / Tauber, M / Maffei, M / Orrù, P / Polato, R / Cretella, E / Ferro, F

    Der Radiologe

    2021  Volume 62, Issue 4, Page(s) 327–330

    Title translation Rare soft tissue tumour of the skin of the chest.
    MeSH term(s) Humans ; Sarcoma ; Soft Tissue Neoplasms/diagnostic imaging ; Soft Tissue Neoplasms/pathology ; Thorax/pathology
    Language German
    Publishing date 2021-10-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 505520-9
    ISSN 1432-2102 ; 0033-832X
    ISSN (online) 1432-2102
    ISSN 0033-832X
    DOI 10.1007/s00117-021-00927-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Surgical management of a free-floating thrombus in the ascending aorta.

    Campanile, Alfonso / Sardone, Mariagrazia / Pasquino, Stefano / Cagini, Angelo / Di Manici, Gino / Cavallini, Claudio

    Asian cardiovascular & thoracic annals

    2018  Volume 27, Issue 3, Page(s) 221–223

    Abstract: The ascending aorta is an uncommon site of noninfective thrombus. We describe the case of a 63-year-old woman who was admitted to our department with acute myocardial infarction. Coronary angiography showed occlusion of a small diagonal vessel, likely ... ...

    Abstract The ascending aorta is an uncommon site of noninfective thrombus. We describe the case of a 63-year-old woman who was admitted to our department with acute myocardial infarction. Coronary angiography showed occlusion of a small diagonal vessel, likely related to a distal embolization event. A transthoracic echocardiogram revealed a free-floating mass in the proximal ascending aorta. Two-and 3-dimensional transesophageal echocardiography studies were performed, and after a multidisciplinary heart team discussion, surgical removal of the mass was planned and successfully performed through a median sternotomy on cardiopulmonary bypass.
    MeSH term(s) Aortic Diseases/diagnostic imaging ; Aortic Diseases/surgery ; Arterial Occlusive Diseases/diagnostic imaging ; Arterial Occlusive Diseases/surgery ; Cardiopulmonary Bypass ; Coronary Angiography ; Echocardiography, Three-Dimensional ; Echocardiography, Transesophageal ; Female ; Humans ; Middle Aged ; Sternotomy ; Thrombectomy/methods ; Thrombosis/diagnostic imaging ; Thrombosis/surgery ; Treatment Outcome
    Language English
    Publishing date 2018-09-24
    Publishing country England
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 1400468-9
    ISSN 1816-5370 ; 0218-4923
    ISSN (online) 1816-5370
    ISSN 0218-4923
    DOI 10.1177/0218492318804956
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Digital Pathology During the COVID-19 Outbreak in Italy: Survey Study.

    Giaretto, Simone / Renne, Salvatore Lorenzo / Rahal, Daoud / Bossi, Paola / Colombo, Piergiuseppe / Spaggiari, Paola / Manara, Sofia / Sollai, Mauro / Fiamengo, Barbara / Brambilla, Tatiana / Fernandes, Bethania / Rao, Stefania / Elamin, Abubaker / Valeri, Marina / De Carlo, Camilla / Belsito, Vincenzo / Lancellotti, Cesare / Cieri, Miriam / Cagini, Angelo /
    Terracciano, Luigi / Roncalli, Massimo / Di Tommaso, Luca

    Journal of medical Internet research

    2021  Volume 23, Issue 2, Page(s) e24266

    Abstract: Background: Transition to digital pathology usually takes months or years to be completed. We were familiarizing ourselves with digital pathology solutions at the time when the COVID-19 outbreak forced us to embark on an abrupt transition to digital ... ...

    Abstract Background: Transition to digital pathology usually takes months or years to be completed. We were familiarizing ourselves with digital pathology solutions at the time when the COVID-19 outbreak forced us to embark on an abrupt transition to digital pathology.
    Objective: The aim of this study was to quantitatively describe how the abrupt transition to digital pathology might affect the quality of diagnoses, model possible causes by probabilistic modeling, and qualitatively gauge the perception of this abrupt transition.
    Methods: A total of 17 pathologists and residents participated in this study; these participants reviewed 25 additional test cases from the archives and completed a final psychologic survey. For each case, participants performed several different diagnostic tasks, and their results were recorded and compared with the original diagnoses performed using the gold standard method (ie, conventional microscopy). We performed Bayesian data analysis with probabilistic modeling.
    Results: The overall analysis, comprising 1345 different items, resulted in a 9% (117/1345) error rate in using digital slides. The task of differentiating a neoplastic process from a nonneoplastic one accounted for an error rate of 10.7% (42/392), whereas the distinction of a malignant process from a benign one accounted for an error rate of 4.2% (11/258). Apart from residents, senior pathologists generated most discrepancies (7.9%, 13/164). Our model showed that these differences among career levels persisted even after adjusting for other factors.
    Conclusions: Our findings are in line with previous findings, emphasizing that the duration of transition (ie, lengthy or abrupt) might not influence the diagnostic performance. Moreover, our findings highlight that senior pathologists may be limited by a digital gap, which may negatively affect their performance with digital pathology. These results can guide the process of digital transition in the field of pathology.
    MeSH term(s) Bayes Theorem ; COVID-19/epidemiology ; Clinical Competence ; Diagnostic Imaging/methods ; Diagnostic Imaging/standards ; Disease Outbreaks ; Humans ; Image Processing, Computer-Assisted/methods ; Image Processing, Computer-Assisted/standards ; Internship and Residency/methods ; Internship and Residency/standards ; Italy/epidemiology ; Microscopy ; Pathology, Clinical/methods ; Pathology, Clinical/standards ; Surveys and Questionnaires
    Language English
    Publishing date 2021-02-22
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1438-8871
    ISSN (online) 1438-8871
    ISSN 1438-8871
    DOI 10.2196/24266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Intravascular NK/T-cell lymphoma, Epstein-Barr virus positive with multiorgan involvement: a clinical dilemma.

    Zanelli, Magda / Mengoli, Maria Cecilia / Del Sordo, Rachele / Cagini, Angelo / De Marco, Loredana / Simonetti, Edoardo / Martino, Giovanni / Zizzo, Maurizio / Ascani, Stefano

    BMC cancer

    2018  Volume 18, Issue 1, Page(s) 1115

    Abstract: Background: Intravascular lymphoma is a rare type of non-Hodgkin lymphoma mostly of B-cell lineage. A few cases of intravascular lymphoma have been found to be of NK/T-cell origin, mainly affecting the skin and central nervous system.: Case ... ...

    Abstract Background: Intravascular lymphoma is a rare type of non-Hodgkin lymphoma mostly of B-cell lineage. A few cases of intravascular lymphoma have been found to be of NK/T-cell origin, mainly affecting the skin and central nervous system.
    Case presentation: A 54-year-old Caucasian man sought care because of a 2 weeks history of jaundice and intermittent fever, not responsive to antibiotics and antipyretics. Laboratory tests showed low blood oxygen concentration and pancytopenia. Serum microbiological tests were negative. Computerized tomography (CT) scan revealed hepatosplenomegaly and diffuse ground-glass opacities in both lungs without interlobular septal thickening. Despite oxygen therapy, the clinical conditions rapidly deteriorated leading to death 3 days after admission. Autopsy revealed a multiorgan involvement by an Epstein-Barr virus positive NK/T-cell lymphoma, strikingly growing within the blood vessel lumina, in absence of skin lesions.
    Conclusions: The current case highlights the pathological features of this rare entity, the protean clinical presentation of which is often misleading, resulting in delayed diagnosis and treatment.
    MeSH term(s) Delayed Diagnosis ; Epstein-Barr Virus Infections/complications ; Epstein-Barr Virus Infections/diagnosis ; Epstein-Barr Virus Infections/virology ; Fatal Outcome ; Hepatomegaly/diagnostic imaging ; Hepatomegaly/virology ; Herpesvirus 4, Human/isolation & purification ; Humans ; Lung/diagnostic imaging ; Lung Neoplasms/diagnosis ; Lung Neoplasms/secondary ; Lung Neoplasms/therapy ; Lung Neoplasms/virology ; Lymphoma, Extranodal NK-T-Cell/complications ; Lymphoma, Extranodal NK-T-Cell/diagnosis ; Lymphoma, Extranodal NK-T-Cell/pathology ; Lymphoma, Extranodal NK-T-Cell/virology ; Male ; Middle Aged ; Oxygen Inhalation Therapy ; Splenomegaly/diagnostic imaging ; Splenomegaly/virology ; Tomography, X-Ray Computed
    Language English
    Publishing date 2018-11-15
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1471-2407
    ISSN (online) 1471-2407
    DOI 10.1186/s12885-018-5001-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Digital Pathology During the COVID-19 Outbreak in Italy

    Giaretto, Simone / Renne, Salvatore Lorenzo / Rahal, Daoud / Bossi, Paola / Colombo, Piergiuseppe / Spaggiari, Paola / Manara, Sofia / Sollai, Mauro / Fiamengo, Barbara / Brambilla, Tatiana / Fernandes, Bethania / Rao, Stefania / Elamin, Abubaker / Valeri, Marina / De Carlo, Camilla / Belsito, Vincenzo / Lancellotti, Cesare / Cieri, Miriam / Cagini, Angelo /
    Terracciano, Luigi / Roncalli, Massimo / Di Tommaso, Luca

    Journal of Medical Internet Research, Vol 23, Iss 2, p e

    Survey Study

    2021  Volume 24266

    Abstract: BackgroundTransition to digital pathology usually takes months or years to be completed. We were familiarizing ourselves with digital pathology solutions at the time when the COVID-19 outbreak forced us to embark on an abrupt transition to digital ... ...

    Abstract BackgroundTransition to digital pathology usually takes months or years to be completed. We were familiarizing ourselves with digital pathology solutions at the time when the COVID-19 outbreak forced us to embark on an abrupt transition to digital pathology. ObjectiveThe aim of this study was to quantitatively describe how the abrupt transition to digital pathology might affect the quality of diagnoses, model possible causes by probabilistic modeling, and qualitatively gauge the perception of this abrupt transition. MethodsA total of 17 pathologists and residents participated in this study; these participants reviewed 25 additional test cases from the archives and completed a final psychologic survey. For each case, participants performed several different diagnostic tasks, and their results were recorded and compared with the original diagnoses performed using the gold standard method (ie, conventional microscopy). We performed Bayesian data analysis with probabilistic modeling. ResultsThe overall analysis, comprising 1345 different items, resulted in a 9% (117/1345) error rate in using digital slides. The task of differentiating a neoplastic process from a nonneoplastic one accounted for an error rate of 10.7% (42/392), whereas the distinction of a malignant process from a benign one accounted for an error rate of 4.2% (11/258). Apart from residents, senior pathologists generated most discrepancies (7.9%, 13/164). Our model showed that these differences among career levels persisted even after adjusting for other factors. ConclusionsOur findings are in line with previous findings, emphasizing that the duration of transition (ie, lengthy or abrupt) might not influence the diagnostic performance. Moreover, our findings highlight that senior pathologists may be limited by a digital gap, which may negatively affect their performance with digital pathology. These results can guide the process of digital transition in the field of pathology.
    Keywords Computer applications to medicine. Medical informatics ; R858-859.7 ; Public aspects of medicine ; RA1-1270
    Subject code 001
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher JMIR Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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