LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 745

Search options

  1. Article: Perspective of

    Cai, Lu

    Dose-response : a publication of International Hormesis Society

    2024  Volume 22, Issue 2, Page(s) 15593258241248775

    Abstract: This is an editorial from the new editor-in-chief, EIC, who starts his role in March 2024. Due to the remarkable advance of various research fields in terms of its concepts and technology, the emerging concepts of "Exposome" and associated "Exposomics" ... ...

    Abstract This is an editorial from the new editor-in-chief, EIC, who starts his role in March 2024. Due to the remarkable advance of various research fields in terms of its concepts and technology, the emerging concepts of "Exposome" and associated "Exposomics" have been introduced into the toxicology research. Therefore, the mission of
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Editorial
    ZDB-ID 2440820-7
    ISSN 1559-3258
    ISSN 1559-3258
    DOI 10.1177/15593258241248775
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Impact of Nutrition or FDA-Approved Medicine Repurposing on Metabolic Syndrome and Diabetic Complications.

    Cai, Lu

    Nutrients

    2023  Volume 15, Issue 11

    Abstract: Both obesity and diabetes are global health threats due to their high risk of developing different complications [ ... ]. ...

    Abstract Both obesity and diabetes are global health threats due to their high risk of developing different complications [...].
    MeSH term(s) Humans ; Metabolic Syndrome/complications ; Metabolic Syndrome/drug therapy ; Diabetes Mellitus/drug therapy ; Diabetes Complications/drug therapy ; Diabetes Complications/complications ; Obesity/complications ; Obesity/drug therapy
    Language English
    Publishing date 2023-05-29
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15112515
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Prevention or therapy of the diabetic cardiomyopathy by fine O-GlcNAcylation balance: hopes and concerns.

    Cai, Lu

    Cardiovascular research

    2021  Volume 118, Issue 1, Page(s) 7–9

    MeSH term(s) Animals ; Diabetes Mellitus, Experimental ; Diabetic Cardiomyopathies/prevention & control ; Myocytes, Cardiac
    Language English
    Publishing date 2021-07-12
    Publishing country England
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80340-6
    ISSN 1755-3245 ; 0008-6363
    ISSN (online) 1755-3245
    ISSN 0008-6363
    DOI 10.1093/cvr/cvab226
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 565: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Seismic Velocity Inversion via Physical Embedding Recurrent Neural Networks (RNN)

    Cai Lu / Chunlong Zhang

    Applied Sciences, Vol 13, Iss 24, p

    2023  Volume 13312

    Abstract: Seismic velocity inversion is one of the most critical issues in the field of seismic exploration and has long been the focus of numerous experts and scholars. In recent years, the advancement of machine learning technologies has infused new vitality ... ...

    Abstract Seismic velocity inversion is one of the most critical issues in the field of seismic exploration and has long been the focus of numerous experts and scholars. In recent years, the advancement of machine learning technologies has infused new vitality into the research of seismic velocity inversion and yielded a wealth of research outcomes. Typically, seismic velocity inversion based on machine learning lacks control over physical processes and interpretability. Starting from wave theory and the physical processes of seismic data acquisition, this paper proposes a method for seismic velocity model inversion based on Physical Embedding Recurrent Neural Networks. Firstly, the wave equation is a mathematical representation of the physical process of acoustic waves propagating through a medium, and the finite difference method is an effective approach to solving the wave equation. With this in mind, we introduce the architecture of recurrent neural networks to describe the finite difference solution of the wave equation, realizing the embedding of physical processes into machine learning. Secondly, in seismic data acquisition, the propagation of acoustic waves from multiple sources through the medium represents a high-dimensional causal time series (wavefield snapshots), where the influential variable is the velocity model, and the received signals are the observations of the wavefield. This forms a forward modeling process as the forward simulation of the wavefield equation, and the use of error back-propagation between observations and calculations as the velocity inversion process. Through time-lapse inversion and by incorporating the causal information of wavefield propagation, the non-uniqueness issue in velocity inversion is mitigated. Through mathematical derivations and theoretical model analyses, the effectiveness and rationality of the method are demonstrated. In conjunction with simulation results for complex models, the method proposed in this paper can achieve velocity inversion in complex geological ...
    Keywords velocity modeling ; seismic waveform inversion ; physical information neural network ; causal sequence ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 550
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: Glucagon-like-peptide-1 receptor agonists and the management of type 2 diabetes-backwards and forwards.

    Horowitz, Michael / Cai, Lu / Islam, Md Shahidul

    World journal of diabetes

    2024  Volume 15, Issue 3, Page(s) 326–330

    Abstract: This editorial is stimulated by the article by ... ...

    Abstract This editorial is stimulated by the article by Alqifari
    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Editorial
    ZDB-ID 2583471-X
    ISSN 1948-9358
    ISSN 1948-9358
    DOI 10.4239/wjd.v15.i3.326
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Alzheimer's disease and low-dose radiation therapy: A new hope.

    Dunlap, Neal E / Friedland, Robert P / Cai, Lu

    Radiation medicine and protection

    2024  Volume 5, Issue 1, Page(s) 1–6

    Abstract: The concept of low-dose radiation (LDR)-induced hormetic responses was initially observed approximately 70 years ago and systematically reviewed along with the discovery of LDR-induced adaptive responses in a ... ...

    Abstract The concept of low-dose radiation (LDR)-induced hormetic responses was initially observed approximately 70 years ago and systematically reviewed along with the discovery of LDR-induced adaptive responses in a cytogenetic
    Language English
    Publishing date 2024-02-07
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-5557
    ISSN (online) 2666-5557
    DOI 10.1016/j.radmp.2024.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Diabetic Cardiomyopathy and Cell Death: Focus on Metal-Mediated Cell Death.

    Cai, Lu / Tan, Yi / Holland, Brian / Wintergerst, Kupper

    Cardiovascular toxicology

    2024  Volume 24, Issue 2, Page(s) 71–84

    Abstract: Cardiac myocyte death is an essential initiator of the pathogenesis and progression of various etiological cardiomyopathies, including diabetic cardiomyopathy (DCM), a disease that has been reported since 1972. Cardiac cell death has been detected in the ...

    Abstract Cardiac myocyte death is an essential initiator of the pathogenesis and progression of various etiological cardiomyopathies, including diabetic cardiomyopathy (DCM), a disease that has been reported since 1972. Cardiac cell death has been detected in the hearts of patients with diabetes and in animal models, and the role of cell death in the pathogenesis of DCM has been extensively investigated. The first review by the authors, specifically focusing on "Cell death and diabetic cardiomyopathy," was published in the journal, Cardiovascular Toxicology in 2003. Over the past two decades, studies investigating the role of cardiac cell death in the pathogenesis of DCM have gained significant attention, resulting in the discovery of several new kinds of cell death involving different mechanisms, including apoptosis, necroptosis, pyroptosis, autophagy, ferroptosis, and cuproptosis. After the 20th anniversary of the review published in 2003, we now provide an update with a focus on the potential role of metal-mediated cell death, ferroptosis, and cuproptosis in the development of DCM in compliance with this special issue. The intent of our review is to further stimulate work in the field to advance the body of knowledge and continue to drive efforts to develop more advanced therapeutic approaches to prevent cell death, particularly metal-dependent cell death, and, ultimately, to reduce or prevent the development of DCM.
    MeSH term(s) Animals ; Humans ; Diabetic Cardiomyopathies/metabolism ; Cell Death ; Apoptosis ; Myocytes, Cardiac/metabolism ; Pyroptosis ; Metals ; Diabetes Mellitus/metabolism ; Diabetes Mellitus/pathology
    Chemical Substances Metals
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2036765-X
    ISSN 1559-0259 ; 1530-7905
    ISSN (online) 1559-0259
    ISSN 1530-7905
    DOI 10.1007/s12012-024-09836-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5817: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Editorial: Cardiovascular diseases related to diabetes and obesity, volume III.

    Xin, Ying / Wise, Jamie Young / Rajesh, Mohanraj / Cai, Lu

    Frontiers in endocrinology

    2024  Volume 15, Page(s) 1381446

    MeSH term(s) Humans ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Obesity/complications ; Metabolic Syndrome ; Diabetes Mellitus/epidemiology
    Language English
    Publishing date 2024-02-13
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2024.1381446
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: Recent therapeutic targets for the prevention and management of diabetic complications.

    Islam, Md Shahidul / Cai, Lu / Horowitz, Michael

    World journal of diabetes

    2023  Volume 14, Issue 9, Page(s) 1330–1333

    Abstract: Diabetes and associated complications represent major global public health issues which are associated with impaired quality of life and premature death. Although some diabetic complications have decreased in the developed world, the majority are still ... ...

    Abstract Diabetes and associated complications represent major global public health issues which are associated with impaired quality of life and premature death. Although some diabetic complications have decreased in the developed world, the majority are still prevalent, with an increasing trend in the developing world. Currently used therapies are mainly 'glucocentric', focusing on the optimization of glycemic control to prevent, delay or manage diabetes-associated complications- other common comorbidities, such as dyslipidemia and hypertension are often underestimated. Although a number of novel therapeutic approaches have been reported recently, some of them have not received comparable attention in relation to either further studies or potential clinical implementation. This editorial briefly discusses some recent therapeutic approaches to the prevention and management of diabetes and its associated complications, as well as potential directions for future research and development in this area.
    Language English
    Publishing date 2023-09-19
    Publishing country United States
    Document type Editorial
    ZDB-ID 2583471-X
    ISSN 1948-9358
    ISSN 1948-9358
    DOI 10.4239/wjd.v14.i9.1330
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Potential therapeutic targets for the prevention of diabetic nephropathy: Glycyrrhetinic acid.

    Cai, Lu / Horowitz, Michael / Islam, Md Shahidul

    World journal of diabetes

    2023  Volume 14, Issue 12, Page(s) 1717–1720

    Abstract: Uncontrolled hyperglycemia or poorly managed disease increases the propensity for a number of diabetes-related complications targeting major organs including the heart, eyes, and kidney. Although the mechanisms by which diabetes induces cardiovascular ... ...

    Abstract Uncontrolled hyperglycemia or poorly managed disease increases the propensity for a number of diabetes-related complications targeting major organs including the heart, eyes, and kidney. Although the mechanisms by which diabetes induces cardiovascular diseases include oxidative stress and inflammation, when insulin resistance remains the key to the pathogenesis, as implicated in the two reviews in this issue. This editorial mainly comments on the potential preventive application of glycyrrhetinic acid (or 18β-GA) in relation to diabetic nephropathy. The thera-peutic or preventive effects of 18β-GA, as a hydrolytic product of glycyrrhizic acid that is a component of licorice, have been appreciated in other disorders, but have received much less attention in relation to diabetic complications. A study in this issue has identified 18β-GA as a therapeutic for preventing diabetic nephropathy and provides evidence to support efficacy in cultured human renal tubule cells
    Language English
    Publishing date 2023-12-04
    Publishing country United States
    Document type Editorial
    ZDB-ID 2583471-X
    ISSN 1948-9358
    ISSN 1948-9358
    DOI 10.4239/wjd.v14.i12.1717
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top