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  1. Article ; Online: Insulin based treatment or blood purification for hypertriglyceridaemia-associated acute pancreatitis: Our reply.

    Cai, Wenhao / He, Wenhua / Sutton, Robert / Huang, Wei

    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.

    2022  Volume 23, Issue 1, Page(s) 129–130

    MeSH term(s) Humans ; Insulin/therapeutic use ; Pancreatitis/complications ; Pancreatitis/therapy ; Acute Disease ; Hypertriglyceridemia/complications ; Hypertriglyceridemia/therapy ; Hyperlipidemias
    Chemical Substances Insulin
    Language English
    Publishing date 2022-11-12
    Publishing country Switzerland
    Document type Letter ; Comment
    ZDB-ID 2056680-3
    ISSN 1424-3911 ; 1424-3903
    ISSN (online) 1424-3911
    ISSN 1424-3903
    DOI 10.1016/j.pan.2022.11.002
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    Zs.A 5553: Show issues Location:
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  2. Article ; Online: scMoresDB: A comprehensive database of single-cell multi-omics data for human respiratory system.

    Chen, Kang / Han, Yutong / Wang, Yanni / Zhou, Dingli / Wu, Fanjie / Cai, Wenhao / Zheng, Shikang / Xiao, Qinyuan / Zhang, Haiyue / Li, Weizhong

    iScience

    2024  Volume 27, Issue 4, Page(s) 109567

    Abstract: The human respiratory system is a complex and important system that can suffer a variety of diseases. Single-cell sequencing technologies, applied in many respiratory disease studies, have enhanced our ability in characterizing molecular and phenotypic ... ...

    Abstract The human respiratory system is a complex and important system that can suffer a variety of diseases. Single-cell sequencing technologies, applied in many respiratory disease studies, have enhanced our ability in characterizing molecular and phenotypic features at a single-cell resolution. The exponentially increasing data from these studies have consequently led to difficulties in data sharing and analysis. Here, we present scMoresDB, a single-cell multi-omics database platform with extensive omics types tailored for human respiratory diseases. scMoresDB re-analyzes single-cell multi-omics datasets, providing a user-friendly interface with cross-omics search capabilities, interactive visualizations, and analytical tools for comprehensive data sharing and integrative analysis. Our example applications highlight the potential significance of BSG receptor in SARS-CoV-2 infection as well as the involvement of HHIP and TGFB2 in the development and progression of chronic obstructive pulmonary disease. scMoresDB significantly increases accessibility and utility of single-cell data relevant to human respiratory system and associated diseases.
    Language English
    Publishing date 2024-03-26
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2024.109567
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  3. Book ; Online: Non-Cooperative Resource Management for Intelligent Reflecting Surface Aided Networks

    Cai, Wenhao / Li, Ming / Liu, Qian

    2022  

    Abstract: Intelligent reflecting surface (IRS) has emerged as a promising and revolutionizing technology for future wireless networks. Most existing IRS studies focus on simple cooperative systems which usually have a single frequency band. In realistic non- ... ...

    Abstract Intelligent reflecting surface (IRS) has emerged as a promising and revolutionizing technology for future wireless networks. Most existing IRS studies focus on simple cooperative systems which usually have a single frequency band. In realistic non-cooperative multi-band networks, however, the existing IRS designs may be not applicable or have severe performance degradation. Thus, in the complex network environment, it is more rational to consider IRSs as public resources to be dynamically allocated to appropriate users. In this paper, we first introduce the auction theory to tackle the resource management problem for a multi-IRS-assisted non-cooperative network. An efficient auction algorithm framework is introduced to sub-optimally solve this non-convex problem. Simulation result illustrates that the significant performance improvement can be achieved by applying the auction algorithm in the complex multi-IRS-assisted non-cooperative network.

    Comment: 5 pages, 3 figures, accepted by IEEE Transactions on Vehicular Technology
    Keywords Electrical Engineering and Systems Science - Signal Processing
    Publishing date 2022-09-01
    Publishing country us
    Document type Book ; Online
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  4. Article ; Online: A study on the hydrodynamic performance of manta ray biomimetic glider under unconstrained six-DOF motion.

    Cai, Wen-Hao / Zhan, Jie-Min / Luo, Ying-Ying

    PloS one

    2020  Volume 15, Issue 11, Page(s) e0241677

    Abstract: A manta ray biomimetic glider is designed and studied with both laboratory experiments and numerical simulations with a new dynamic update method called the motion-based zonal mesh update method (MBZMU method) to reveal its hydrodynamic performance. ... ...

    Abstract A manta ray biomimetic glider is designed and studied with both laboratory experiments and numerical simulations with a new dynamic update method called the motion-based zonal mesh update method (MBZMU method) to reveal its hydrodynamic performance. Regarding the experimental study, an ejection gliding experiment is conducted for qualitative verification, and a hydrostatic free-fall experiment is conducted to quantitatively verify the reliability of the corresponding numerical simulation. Regarding the numerical simulation, to reduce the trend of nose-up movement and to obtain a long lasting and stable gliding motion, a series of cases with the center of mass offset forward by different distances and different initial angles of attack have been calculated. The results show that the glider will show the optimal gliding performance when the center of mass is 20mm in front of the center of geometry and the initial attack angle range lies between A0 = -5° to A0 = -2.5° at the same time. The optimal gliding distance can reach six times its body length under these circumstances. Furthermore, the stability of the glider is explained from the perspective of Blended-Wing-Body (BWB) configuration.
    MeSH term(s) Biomimetics/methods ; Computer Simulation ; Hydrodynamics ; Temperature
    Language English
    Publishing date 2020-11-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0241677
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  5. Article ; Online: Preparation of TiO

    Lin, Jianguo / Cai, Wenhao / Peng, Qing / Meng, Fanbin / Zhang, Dechuang

    Scanning

    2021  Volume 2021, Page(s) 2717921

    Abstract: In this work, a highly ordered ... ...

    Abstract In this work, a highly ordered TiO
    Language English
    Publishing date 2021-12-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 391900-6
    ISSN 1932-8745 ; 0161-0457
    ISSN (online) 1932-8745
    ISSN 0161-0457
    DOI 10.1155/2021/2717921
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3871: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Molecular mechanisms of pain in acute pancreatitis: recent basic research advances and therapeutic implications.

    Wu, Yongzi / Han, Chenxia / Luo, Rong / Cai, Wenhao / Xia, Qing / Jiang, Ruotian / Ferdek, Pawel E / Liu, Tingting / Huang, Wei

    Frontiers in molecular neuroscience

    2023  Volume 16, Page(s) 1331438

    Abstract: Although severe abdominal pain is the main symptom of acute pancreatitis, its mechanisms are poorly understood. An emerging body of literature evidence indicates that neurogenic inflammation might play a major role in modulating the perception of pain ... ...

    Abstract Although severe abdominal pain is the main symptom of acute pancreatitis, its mechanisms are poorly understood. An emerging body of literature evidence indicates that neurogenic inflammation might play a major role in modulating the perception of pain from the pancreas. Neurogenic inflammation is the result of a crosstalk between injured pancreatic tissue and activated neurons, which leads to an auto-amplification loop between inflammation and pain during the progression of acute pancreatitis. In this review, we summarize recent findings on the role of neuropeptides, ion channels, and the endocannabinoid system in acute pancreatitis-related pain. We also highlight potential therapeutic strategies that could be applied for managing severe pain in this disease.
    Language English
    Publishing date 2023-12-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2452967-9
    ISSN 1662-5099
    ISSN 1662-5099
    DOI 10.3389/fnmol.2023.1331438
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  7. Book ; Online: Joint Beamforming Design for Intelligent Omni Surface Assisted Wireless Communication Systems

    Cai, Wenhao / Li, Ming / Liu, Yang / Wu, Qingqing / Liu, Qian

    2022  

    Abstract: Intelligent reflecting surface (IRS) has been widely considered as one of the key enabling techniques for future wireless communication networks owing to its ability of dynamically controlling the phase shift of reflected electromagnetic (EM) waves to ... ...

    Abstract Intelligent reflecting surface (IRS) has been widely considered as one of the key enabling techniques for future wireless communication networks owing to its ability of dynamically controlling the phase shift of reflected electromagnetic (EM) waves to construct a favorable propagation environment. While IRS only focuses on signal reflection, the recently emerged innovative concept of intelligent omni-surface (IOS) can provide the dual functionality of manipulating reflecting and transmitting signals. Thus, IOS is a new paradigm for achieving ubiquitous wireless communications. In this paper, we consider an IOSassisted multi-user multi-input single-output (MU-MISO) system where the IOS utilizes its reflective and transmissive properties to enhance the MU-MISO transmission. Both power minimization and sum-rate maximization problems are solved by exploiting the second-order cone programming (SOCP), Riemannian manifold, weighted minimum mean square error (WMMSE), and block coordinate descent (BCD) methods. Simulation results verify the advancements of the IOS for wireless systems and illustrate the significant performance improvement of our proposed joint transmit beamforming, reflecting and transmitting phase-shift, and IOS energy division design algorithms. Compared with conventional IRS, IOS can significantly extend the communication coverage, enhance the strength of received signals, and improve the quality of communication links.

    Comment: 16pages, 14 figures, accepted by IEEE Transactions on Wireless Communications
    Keywords Electrical Engineering and Systems Science - Signal Processing
    Subject code 003
    Publishing date 2022-08-31
    Publishing country us
    Document type Book ; Online
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  8. Book ; Online: Practical Modeling and Beamforming for Intelligent Reflecting Surface Aided Wideband Systems

    Cai, Wenhao / Li, Hongyu / Li, Ming / Liu, Qian

    2020  

    Abstract: Intelligent reflecting surface (IRS) has emerged as a revolutionizing solution to enhance wireless communications by intelligently changing the propagation environment. Prior studies on IRS are based on an ideal reflection model with a constant amplitude ...

    Abstract Intelligent reflecting surface (IRS) has emerged as a revolutionizing solution to enhance wireless communications by intelligently changing the propagation environment. Prior studies on IRS are based on an ideal reflection model with a constant amplitude and a variable phase shift. However, it is difficult and unrealistic to implement an IRS satisfying such ideal reflection model in practical applications. In this letter, we aim to investigate the phase-amplitude-frequency relationship of the reflected signals and propose a practical model of reflection coefficient for an IRS-aided wideband system. Then, based on this practical model, joint transmit power allocation of each subcarrier and IRS beamforming optimization are investigated for an IRS-aided wideband orthogonal frequency-division multiplexing (OFDM) system. Simulation results illustrate the importance of the practical model on the IRS designs and validate the effectiveness of our proposed model.

    Comment: 12 pages, 6 figures, to appear in IEEE Communications Letters
    Keywords Electrical Engineering and Systems Science - Signal Processing
    Publishing date 2020-06-02
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Book ; Online: Intelligent reflecting surface assisted multi-cell multi-band wireless networks

    Cai, Wenhao / Liu, Rang / Liu, Yang / Li, Ming / Liu, Qian

    2021  

    Abstract: Intelligent reflecting surface (IRS) is deemed as a promising and revolutionizing technology for future wireless communication systems owing to its capability to intelligently change the propagation environment and introduce a new dimension into wireless ...

    Abstract Intelligent reflecting surface (IRS) is deemed as a promising and revolutionizing technology for future wireless communication systems owing to its capability to intelligently change the propagation environment and introduce a new dimension into wireless communication optimization. Most existing studies on IRS are based on an ideal reflection model. However, it is difficult to implement an IRS which can simultaneously realize any adjustable phase shift for the signals with different frequencies. Therefore, the practical phase shift model, which can describe the difference of IRS phase shift responses for the signals with different frequencies, should be utilized in the IRS optimization for wideband and multi-band systems. In this paper, we consider an IRS-assisted multi-cell multi-band system, in which different base stations (BSs) operate at different frequency bands. We aim to jointly design the transmit beamforming of BSs and the reflection beamforming of the IRS to minimize the total transmit power subject to signal to interference-plus-noise ratio (SINR) constraints of individual user and the practical IRS reflection model. With the aid of the practical phase shift model, the influence between the signals with different frequencies is taken into account during the design of IRS. Simulation results illustrate the importance of considering the practical communication scenario on the IRS designs and validate the effectiveness of our proposed algorithm.

    Comment: 17 pages, 5 figures,submitted to IEEE Wireless Communications and Networking Conference (WCNC) 2021
    Keywords Electrical Engineering and Systems Science - Signal Processing
    Subject code 600
    Publishing date 2021-01-05
    Publishing country us
    Document type Book ; Online
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  10. Article ; Online: Impact of multiple drug-resistant Gram-negative bacterial bacteraemia on infected pancreatic necrosis patients.

    Wu, Di / Jia, Yan / Cai, Wenhao / Huang, Yilin / Kattakayam, Arjun / Latawiec, Diane / Sutton, Robert / Peng, Jie

    Frontiers in cellular and infection microbiology

    2022  Volume 12, Page(s) 1044188

    Abstract: Introduction: Multiple drug-resistant Gram-negative bacterial (MDR-GNB) bacteraemia poses a serious threat to patients in hospital. Infected pancreatic necrosis (IPN) patients are a vulnerable population to infectious complications during ... ...

    Abstract Introduction: Multiple drug-resistant Gram-negative bacterial (MDR-GNB) bacteraemia poses a serious threat to patients in hospital. Infected pancreatic necrosis (IPN) patients are a vulnerable population to infectious complications during hospitalization. This study aims to evaluate the impact of MDR Gram-negative bacteraemia on IPN patients.
    Methods: A case-control study was performed with data collected from 1 January 2016 to 1 July 2022 in a Chinese tertiary teaching hospital. Clinical data of the IPN patients with MDR-GNB bacteraemia were analyzed and compared to those of a matched control group without MDR-GNB bacteraemia (case-control ratio of 1:2). Comparisons were performed between with/without MDR-GNB bacteraemia and different severities of acute pancreatitis (AP). Independent predictors of overall mortality were identified
    Results: MDR-GNB bacteraemia was related to a higher mortality rate (62.5% vs. 8.3%,
    Conclusion: A higher mortality rate in IPN patients was related to MDR-GNB bacteraemia and further increased in severe AP patients combined with MDR-GNB bacteraemia.
    Language English
    Publishing date 2022-11-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2022.1044188
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