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  1. Article ; Online: Optimized Leaky-Wave Antenna for Hyperthermia in Biological Tissue Theoretical Model.

    Calcaterra, Alessandro / Simeoni, Patrizio / Migliore, Marco Donald / Mangini, Fabio / Frezza, Fabrizio

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 21

    Abstract: In this paper, we exploit the enhanced penetration reachable through inhomogeneous waves to induce hyperthermia in biological tissues. We will present a leaky-wave antenna inspired by the Menzel antenna which has been shortened through opportune design ... ...

    Abstract In this paper, we exploit the enhanced penetration reachable through inhomogeneous waves to induce hyperthermia in biological tissues. We will present a leaky-wave antenna inspired by the Menzel antenna which has been shortened through opportune design and optimizations and that has been designed to optimize the penetration at the interface with the skin, allowing penetration in the skin layer at a constant temperature, and enhanced penetration in the overall structure considered. Past papers both numerically and analytically demonstrated the possibility of reducing the attenuation that the electromagnetic waves are subject to when travelling inside a lossy medium by using inhomogeneous waves. In those papers, a structure (the leaky-wave antenna) is shown to allow the effect, but such a radiator suffers from low efficiency. Also, at the frequencies that are most used for hyperthermia application, a classical leaky-wave antenna would be too long; here is where the idea of the shortened leaky-wave arises. To numerically analyze the penetration in biological tissues, this paper considers a numerical prototype of a sample of flesh, composed of superficial skin layers, followed by fat and an undefined layer of muscles.
    MeSH term(s) Hyperthermia, Induced ; Models, Theoretical
    Language English
    Publishing date 2023-11-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23218923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Verification of the electromagnetic deep-penetration effect in the real world.

    Baccarelli, Paolo / Calcaterra, Alessandro / Frezza, Fabrizio / Mangini, Fabio / Ricciardella, Nicholas / Simeoni, Patrizio / Tedeschi, Nicola

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 15928

    Abstract: The deep penetration of electromagnetic waves into lossy media can be obtained by properly generating inhomogeneous waves. In this work, for the very first time, we demonstrate the physical implementation and the practical relevance of this phenomenon. A ...

    Abstract The deep penetration of electromagnetic waves into lossy media can be obtained by properly generating inhomogeneous waves. In this work, for the very first time, we demonstrate the physical implementation and the practical relevance of this phenomenon. A thorough numerical investigation of the deep-penetration effects has been performed by designing and comparing three distinct practical radiators, emitting either homogeneous or inhomogeneous waves. As concerns the latter kind, a typical Menzel microstrip antenna is first used to radiate improper leaky waves. Then, a completely new approach based on an optimized 3-D horn TEM antenna applied to a lossy prism is described, which may find applications even at optical frequencies. The effectiveness of the proposed radiators is measured using different algorithms to consider distinct aspects of the propagation in lossy media. We finally demonstrate that the deep penetration is possible, by extending the ideal and theoretical evidence to practical relevance, and discuss both achievements and limits obtained through numerical simulations on the designed antennas.
    Language English
    Publishing date 2021-08-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-95080-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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