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  1. Article ; Online: Úlceras cutáneas asociadas a dermatomiositis MDA5.

    Martínez-Díaz, Laura / Jiménez-de la Cruz, Laura / Moret-Rueda, Marta / Calero-Paniagua, Ismael

    Medicina clinica

    2022  Volume 160, Issue 3, Page(s) 143

    Title translation Skin ulcers associated with dermatomyositis MDA5.
    MeSH term(s) Humans ; Dermatomyositis/complications ; Dermatomyositis/diagnosis ; Skin Ulcer/etiology ; Autoantibodies ; Interferon-Induced Helicase, IFIH1
    Chemical Substances Autoantibodies ; Interferon-Induced Helicase, IFIH1 (EC 3.6.4.13)
    Language Spanish
    Publishing date 2022-11-26
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2022.09.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.279: Show issues Location:
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  2. Article: Genistein supplementation has no effects on vitamin D levels in healthy Spanish postmenopausal women.

    Pérez-Alonso, María / Calero-Paniagua, Ismael / Usategui-Martin, Ricardo / Briongos, Laisa-Socorro / Ruiz-Mambrilla, Marta / Olmos, José-Manuel / González-Sagrado, Manuel / De Luis, Daniel / Dueñas-Laita, Antonio / Pérez-Castrillón, José-Luis

    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition

    2023  

    Language English
    Publishing date 2023-03-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 120692-8
    ISSN 0300-9831
    ISSN 0300-9831
    DOI 10.1024/0300-9831/a000781
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Cardiogenic shock and lower limb ischemia as complications of Kawasaki disease.

    Usategui-Martín, Iciar / Calero-Paniagua, Ismael / Barbado-Ajo, M Julia

    Medicina clinica

    2017  Volume 149, Issue 12, Page(s) 558–559

    Title translation Shock cardiogénico e isquemia aguda de miembros inferiores como complicaciones de la enfermedad de Kawasaki.
    MeSH term(s) Adolescent ; Fatal Outcome ; Humans ; Ischemia/etiology ; Lower Extremity/blood supply ; Male ; Mucocutaneous Lymph Node Syndrome/complications ; Mucocutaneous Lymph Node Syndrome/diagnosis ; Shock, Cardiogenic/etiology
    Language Spanish
    Publishing date 2017-07-31
    Publishing country Spain
    Document type Case Reports ; Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2017.06.043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.279: Show issues Location:
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  4. Article ; Online: A mutation in p62 protein (p. R321C), associated to Paget's disease of bone, causes a blockade of autophagy and an activation of NF-kB pathway.

    Usategui-Martín, Ricardo / Gestoso-Uzal, Nerea / Calero-Paniagua, Ismael / De Pereda, José María / Del Pino-Montes, Javier / González-Sarmiento, Rogelio

    Bone

    2020  Volume 133, Page(s) 115265

    Abstract: Paget's disease of bone (PDB) is a bone disorder characterized by an increase in bone turnover in a disorganized way with a large increase in bone resorption followed by bone formation. The most important known genetic factor predisposing to PDB is ... ...

    Abstract Paget's disease of bone (PDB) is a bone disorder characterized by an increase in bone turnover in a disorganized way with a large increase in bone resorption followed by bone formation. The most important known genetic factor predisposing to PDB is mutation in Sequestosome1 (SQSTM1) gene. We have studied the prevalence of SQSTM1 mutations and examined genotype-phenotype correlations in a Spanish cohort of PDB patients. Also, we have characterized three PDB patients that carry the c.961C>T SQSTM1 gene mutation that it is localized in exon 6 of SQSTM1 gene and it causes the p. R321C mutation. This mutation has been reported in patients with amyotrophic lateral sclerosis and frontotemporal dementia but in our knowledge this is the first time that p62 p. R321C mutation is associated to PDB. We show that p62 p.R321C mutation could induce blockage of autophagy and cell proliferation through NF-kB pathway. These results reinforce the hypothesis of autophagy involvement in Paget's disease of bone.
    MeSH term(s) Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Autophagy/genetics ; Humans ; Mutation/genetics ; NF-kappa B/metabolism ; Osteitis Deformans/genetics ; RNA-Binding Proteins ; Sequestosome-1 Protein/genetics
    Chemical Substances Adaptor Proteins, Signal Transducing ; NF-kappa B ; P62 protein, human ; RNA-Binding Proteins ; Sequestosome-1 Protein
    Language English
    Publishing date 2020-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632515-4
    ISSN 1873-2763 ; 8756-3282
    ISSN (online) 1873-2763
    ISSN 8756-3282
    DOI 10.1016/j.bone.2020.115265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1571: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MO 332: Show issues

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  5. Article ; Online: Another gouty tophus? The many faces of the enchondroma.

    Calero-Paniagua, Ismael / Vicente-Rodrigo, Julio Alberto / Soliva-Martínez, Daniel / Torrecillas-Fernández, Francisco

    Reumatologia clinica

    2017  Volume 14, Issue 4, Page(s) 239–241

    Title translation ¿Otro tofo gotoso? Las múltiples caras del encondroma.
    MeSH term(s) Aged, 80 and over ; Bone Neoplasms/diagnosis ; Bone Neoplasms/pathology ; Chondroma/diagnosis ; Chondroma/pathology ; Diagnosis, Differential ; Finger Phalanges/diagnostic imaging ; Finger Phalanges/pathology ; Gout/diagnosis ; Humans ; Magnetic Resonance Imaging ; Male
    Language Spanish
    Publishing date 2017-02-24
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ISSN 2173-5743
    ISSN (online) 2173-5743
    DOI 10.1016/j.reuma.2017.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Digital clubbing: A patient with hypertrophic osteoarthropathy and the presence of acro-osteolysis.

    Calero-Paniagua, Ismael / Prieto-Gañán, Luís Miguel / Mora-Peña, Damián / Egea-Aldana, Francisco Ramón

    Reumatologia clinica

    2017  Volume 15, Issue 6, Page(s) e138–e139

    Title translation Hipocratismo digital: paciente con osteoartropatía hipertrófica y presencia de acro-osteólisis.
    MeSH term(s) Acro-Osteolysis/diagnosis ; Acro-Osteolysis/diagnostic imaging ; Aged ; Diagnosis, Differential ; Fingers ; Humans ; Male ; Osteoarthropathy, Secondary Hypertrophic/diagnosis ; Osteoarthropathy, Secondary Hypertrophic/diagnostic imaging ; Toes
    Language Spanish
    Publishing date 2017-12-29
    Publishing country Spain
    Document type Case Reports
    ISSN 2173-5743
    ISSN (online) 2173-5743
    DOI 10.1016/j.reuma.2017.11.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Metallosis as a cause of pain and inflammation in a patient with a knee replacement: A case description.

    Pescador, David / Calero-Paniagua, Ismael / Sánchez-González, María Dolores / Montilla, Carlos

    Reumatologia clinica

    2015  Volume 12, Issue 2, Page(s) 112–113

    MeSH term(s) Aged ; Arthritis/etiology ; Arthroplasty, Replacement, Knee/instrumentation ; Female ; Heavy Metal Poisoning ; Humans ; Knee Prosthesis/adverse effects ; Poisoning/diagnosis ; Poisoning/etiology ; Prosthesis Failure/adverse effects
    Language Spanish
    Publishing date 2015-06-20
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ZDB-ID 2477196-X
    ISSN 1885-1398 ; 1699-258X
    ISSN (online) 1885-1398
    ISSN 1699-258X
    DOI 10.1016/j.reuma.2015.04.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Ochronosis and Osteoporosis: A Case Report.

    Calero Paniagua, Ismael / Montilla Morales, Carlos Alberto / Carranco Medina, Tatiana Elizabeth / Sánchez González, María Dolores

    Reumatologia clinica

    2015  Volume 11, Issue 5, Page(s) 330–331

    MeSH term(s) Alkaptonuria/complications ; Alkaptonuria/diagnosis ; Humans ; Male ; Middle Aged ; Ochronosis/complications ; Ochronosis/diagnosis ; Osteoporosis/diagnosis ; Osteoporosis/etiology
    Language Spanish
    Publishing date 2015-09
    Publishing country Spain
    Document type Case Reports ; Letter
    ZDB-ID 2477196-X
    ISSN 1885-1398 ; 1699-258X
    ISSN (online) 1885-1398
    ISSN 1699-258X
    DOI 10.1016/j.reuma.2015.02.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Proangiogenic gene polymorphisms are associated with susceptibility to Paget's disease of bone and with its clinical features.

    Calero-Paniagua, Ismael / Usategui-Martín, Ricardo / Corral-Gudino, Luís / García-Aparicio, Judit / Del Pino-Montes, Javier / González-Sarmiento, Rogelio

    Clinical and experimental rheumatology

    2017  Volume 35, Issue 3, Page(s) 543

    MeSH term(s) Age of Onset ; Case-Control Studies ; Female ; Gene Frequency ; Genetic Association Studies ; Genetic Predisposition to Disease ; Heterozygote ; Homozygote ; Humans ; Male ; Middle Aged ; Neovascularization, Physiologic/genetics ; Odds Ratio ; Osteitis Deformans/diagnosis ; Osteitis Deformans/genetics ; Osteitis Deformans/physiopathology ; Phenotype ; Polymorphism, Single Nucleotide ; Risk Factors ; Spain ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor Receptor-2/genetics
    Chemical Substances VEGFA protein, human ; Vascular Endothelial Growth Factor A ; KDR protein, human (EC 2.7.10.1) ; Vascular Endothelial Growth Factor Receptor-2 (EC 2.7.10.1)
    Language English
    Publishing date 2017-05
    Publishing country Italy
    Document type Letter
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2002: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Estrogen receptor genes polymorphisms determine serum lipid profile in healthy postmenopausal women treated with calcium, vitamin D, and genistein.

    Usategui-Martín, Ricardo / Pérez-Alonso, María / Socorro-Briongos, Laisa / Ruiz-Mambrilla, Marta / De Luis, Daniel / Linares, Lidia / Calero-Paniagua, Ismael / Dueñas-Laita, Antonio / Pérez-Castrillón, José L

    Journal of cellular biochemistry

    2019  Volume 120, Issue 8, Page(s) 13115–13120

    Abstract: Cardiovascular risk increases in women after menopause. Unfavorable lipid-lipoprotein changes due to a lack of estrogens may have an important role in this context. Estrogen actions are mainly mediated by their binding to two estrogen receptors (ERs) ... ...

    Abstract Cardiovascular risk increases in women after menopause. Unfavorable lipid-lipoprotein changes due to a lack of estrogens may have an important role in this context. Estrogen actions are mainly mediated by their binding to two estrogen receptors (ERs) whose signaling may be conditioned by different factors. Calcium, vitamin D, and genistein, among others, cause a beneficial effect on serum lipid profile by its modulation. Some genetic factors can also determine this signal. We determined the possible additive effect of genistein on calcium and vitamin D supplementation regarding serum lipid profile changes and whether ER polymorphisms may mediate in this effect. We performed a prospective, double blind study in which women were randomized in two groups: one group received calcium and vitamin D and the other group received calcium, vitamin D and genistein. Subsequently, we studied rs9340799, rs928554, and rs4986938 ER polymorphisms in both groups. Our results showed that being a carrier of the variant allele G of rs928554 polymorphism was associated with a greater decrease in triglyceride levels and that the homozygous AA genotype of rs9340799 polymorphism was associated with a greater decrease in total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels after calcium, vitamin D, and genistein supplementation. This is the first report showing an association between polymorphisms in ER genes and an improvement of the serum lipid profile after taking calcium, vitamin D, and genistein supplementation in postmenopausal women. It reinforces the hypothesis that genetic factors are crucial in ER signalling.
    MeSH term(s) Adult ; Calcium/pharmacology ; Double-Blind Method ; Female ; Genistein/pharmacology ; Genotype ; Humans ; Middle Aged ; Polymorphism, Genetic/genetics ; Postmenopause/blood ; Prospective Studies ; Receptors, Estrogen/genetics ; Receptors, Estrogen/metabolism ; Vitamin D/pharmacology
    Chemical Substances Receptors, Estrogen ; Vitamin D (1406-16-2) ; Genistein (DH2M523P0H) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2019-03-18
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 392402-6
    ISSN 1097-4644 ; 0730-2312
    ISSN (online) 1097-4644
    ISSN 0730-2312
    DOI 10.1002/jcb.28584
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1114: Show issues Location:
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