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Article ; Online: Tropikal Olmayan Bölgelerde Uzun Süre Antibiyotik Tedavisine Cevap Vermeyen Fronkül: Gözden Kaçırılmaması Gereken Bir Tanı; Fronküler Kutanöz Miyazis.

Özkol, Hatice Uce / Calka, Omer

Turkiye parazitolojii dergisi

2014 Volume 38, Issue 2, Page(s) 138–140

Abstract: We present the case of a 12-year-old boy with furuncular myiasis living in an area with continental climate. The boy was admitted to our clinic with a wound on his nape, which started as a little acne and progressed to a large wound in which pus flowed ... ...

Title translation	Furuncle persistent to long-term antibiotic therapy in a non-tropical region: a diagnosis that must not be overlooked: furuncular cutaneous myiasis.
Abstract	We present the case of a 12-year-old boy with furuncular myiasis living in an area with continental climate. The boy was admitted to our clinic with a wound on his nape, which started as a little acne and progressed to a large wound in which pus flowed continuously. He complained of itching and was treated with penicillin, clarithromycin, terbinafine, and ibuprofen in the last 2 months, with no big success. Otherwise, the patient was healthy, and his hygienic conditions were within normal standards. The dermatologic examination revealed an off-white ulcer measuring approximately 1x2 cm in the occipital region with regular contours, elevated borders, and purulent flow, while the skin surrounding the ulcer was normal. In the course of the examination, a living larva was removed using a forceps. The ulcer and the surroundings were washed with polyvinylprolidone iodine solution, while fusidic acid pomade was topically applied. The ulcer regressed significantly after 15 days of treatment.
MeSH term(s)	Animals ; Anti-Infective Agents/therapeutic use ; Child ; Diptera/physiology ; Humans ; Larva/physiology ; Male ; Myiasis/diagnosis ; Myiasis/drug therapy ; Myiasis/parasitology ; Myiasis/pathology ; Skin/parasitology ; Skin/pathology
Chemical Substances	Anti-Infective Agents
Language	Turkish
Publishing date	2014-06
Publishing country	Turkey
Document type	Case Reports ; English Abstract ; Journal Article
ISSN	2146-3077
ISSN (online)	2146-3077
DOI	10.5152/tpd.2014.3288
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Article ; Online: Chemotherapy-induced acral erythema with involvement of the face and neck: A case report.

Ozkol, Hatice Uce / Calka, Omer / Bulut, Gulay

Toxicology and industrial health

2016 Volume 32, Issue 5, Page(s) 791–794

Abstract: Chemotherapy-induced acral erythema (CIAE) is a cutaneous response to diverse chemotherapeutic drug administration. These drugs cause symmetrical and painful erythema of palmoplantar surfaces. Bulla formation, desquamation, and subsequent ... ...

Abstract	Chemotherapy-induced acral erythema (CIAE) is a cutaneous response to diverse chemotherapeutic drug administration. These drugs cause symmetrical and painful erythema of palmoplantar surfaces. Bulla formation, desquamation, and subsequent reepithelialization may occur. Commonly, the lesions slowly resolve over 7-15 days, through desquamation, followed by regeneration of the skin. Here, we described a case of CIAE, with involvement of face and neck in a patient treated for breast cancer using a number of chemotherapeutic agents. Face involvement in CIAE has not been previously reported in the literature.
MeSH term(s)	Antineoplastic Agents/adverse effects ; Breast Neoplasms/drug therapy ; Cyclophosphamide/adverse effects ; Cyclophosphamide/therapeutic use ; Dose-Response Relationship, Drug ; Epirubicin/adverse effects ; Epirubicin/therapeutic use ; Face/pathology ; Female ; Hand-Foot Syndrome/diagnosis ; Hand-Foot Syndrome/drug therapy ; Humans ; Neck/pathology ; Pyridoxine/pharmacology ; Skin/drug effects ; Skin/pathology ; Taxoids/adverse effects ; Taxoids/therapeutic use ; Trastuzumab/adverse effects ; Trastuzumab/therapeutic use ; Vitamin B Complex/pharmacology ; Young Adult
Chemical Substances	Antineoplastic Agents ; Taxoids ; Vitamin B Complex (12001-76-2) ; docetaxel (15H5577CQD) ; Epirubicin (3Z8479ZZ5X) ; Cyclophosphamide (8N3DW7272P) ; Pyridoxine (KV2JZ1BI6Z) ; Trastuzumab (P188ANX8CK)
Language	English
Publishing date	2016-05
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	56831-4
ISSN	1477-0393 ; 0748-2337
ISSN (online)	1477-0393
ISSN	0748-2337
DOI	10.1177/0748233713511514
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Article: Is TrichoScan a new diagnostic method for diffuse hair loss?

Uce Özkol, Hatice / Çalka, Ömer / Akdeniz, Necmettin

Turkish journal of medical sciences

2015 Volume 44, Issue 3, Page(s) 432–438

Abstract: Aim: In this study, we investigated the sensitivity of TrichoScan, a computer-based phototrichogram, in the evaluation of diffuse hair loss in women and the relationship between iron deficiency anemia and hair loss.: Materials and methods: We ... ...

Abstract	Aim: In this study, we investigated the sensitivity of TrichoScan, a computer-based phototrichogram, in the evaluation of diffuse hair loss in women and the relationship between iron deficiency anemia and hair loss. Materials and methods: We recruited 100 female patients with diffuse hair loss. In all of the patients, a 1-cm2 area of hair located in a temporoparietal region was shortened to 0.5 mm. The shaved scalp regions were stained with black dye. The subject then waited for 12 min. Subsequently, pictures of these regions were taken with a videodermoscope and analyzed with the TrichoScan software program. Results: The ferritin levels were markedly low in these groups. The ratio of anagen was highest in the telogen effluvium (TE) mild group, followed by the TE severe group, and was lowest in the androgenetic alopecia (AGA) group (P <0.05). The ratio of telogen was markedly higher in the AGA group, and the difference was statistically significant when compared with the other 2 groups (P < 0.05). Conclusion: The hair analysis results with the TrichoScan software were satisfactory and the results were consistent with the clinical diagnosis. In particular, the use of TrichoScan was very successful in the differentiation between AGA and TE.
MeSH term(s)	Adolescent ; Adult ; Alopecia/blood ; Alopecia/diagnosis ; Alopecia/pathology ; Anemia, Iron-Deficiency/blood ; Anemia, Iron-Deficiency/pathology ; Female ; Ferritins/blood ; Hair/pathology ; Humans ; Image Interpretation, Computer-Assisted/methods ; Middle Aged ; Photography/methods ; Scalp/pathology ; Young Adult
Chemical Substances	Ferritins (9007-73-2)
Language	English
Publishing date	2015-01-01
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	1183461-4
ISSN	1303-6165 ; 1300-0144
ISSN (online)	1303-6165
ISSN	1300-0144
DOI	10.3906/sag-1212-78
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Zs.A 3242: Show issues

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Article: Biochemical and histopathologic assessment of effects of acitretin on epiphyseal growth plate in rats.

Onder, Sevda / Bilgili, Serap Gunes / Bulut, Gulay / Celik, Huseyin Tugrul / Oguztuzun, Serpil / Onder, Hacı / Calka, Omer / Karadag, Ayse Serap

Postepy dermatologii i alergologii

2020 Volume 37, Issue 3, Page(s) 346–352

Abstract: Introduction: Acitretin is a commonly used retinoid in dermatology. Although there are generally known side effects, the effects on the epiphyseal plaque and bone metabolism are not clear in the literature.: Aim: To histopathologically investigate ... ...

Abstract	Introduction: Acitretin is a commonly used retinoid in dermatology. Although there are generally known side effects, the effects on the epiphyseal plaque and bone metabolism are not clear in the literature. Aim: To histopathologically investigate the effects on the epiphyseal plate and assess variations in bone metabolism caused by acitretin. Material and methods: Three groups were formed with 10 rats in each group. The 1 Results: Staining with haematoxylin-eosin found reductions in the epiphyseal plate in the 1 Conclusions: Our data show that though acitretin caused degeneration of the epiphyseal plate, it did not cause clear thinning and we identified no significant variations in bone metabolism markers.
Language	English
Publishing date	2020-07-16
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2596142-1
ISSN	1642-395X
ISSN	1642-395X
DOI	10.5114/ada.2020.95983
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Article: Ulcerated giant labial acrochordon in a child.

Ozkol, Hatice Uce / Bulut, Gulay / Gumus, Sibel / Calka, Omer

Indian dermatology online journal

2015 Volume 6, Issue 1, Page(s) 60–61

Language	English
Publishing date	2015-01-22
Publishing country	India
Document type	Journal Article
ZDB-ID	2585814-2
ISSN	2249-5673 ; 2229-5178
ISSN (online)	2249-5673
ISSN	2229-5178
DOI	10.4103/2229-5178.148955
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Article ; Online: Acrodermatitis enteropathica in three siblings.

Karadag, Ayse Serap / Bilgili, Serap Gunes / Calka, Omer

Indian journal of dermatology, venereology and leprology

2013 Volume 79, Issue 2, Page(s) 268

MeSH term(s)	Acrodermatitis/diagnosis ; Acrodermatitis/drug therapy ; Acrodermatitis/genetics ; Child ; Child, Preschool ; Female ; Humans ; Male ; Siblings ; Zinc/deficiency ; Zinc Sulfate/administration & dosage
Chemical Substances	Zinc Sulfate (7733-02-0) ; Zinc (J41CSQ7QDS)
Language	English
Publishing date	2013-03
Publishing country	India
Document type	Case Reports ; Letter
ZDB-ID	416068-x
ISSN	0973-3922 ; 0019-5162 ; 0378-6323
ISSN (online)	0973-3922
ISSN	0019-5162 ; 0378-6323
DOI	10.4103/0378-6323.107667
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Zs.A 85: Show issues

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Article ; Online: The efficiency of granulocyte colony-stimulating factor in hemorrhagic mucositis and febrile neutropenia resulted from methotrexate toxicity.

Ozkol, Hatice Uce / Toptas, Tayfur / Calka, Omer / Akdeniz, Necmettin

Cutaneous and ocular toxicology

2015 Volume 34, Issue 2, Page(s) 173–175

Abstract: Methotrexate (MTX) remains one of the most frequently used anti-metabolite agents in dermatology. MTX is an analog of folate that competitively and irreversibly inhibits dihydrofolate reductase. Oral mucositis is a common side effect of chemotherapy ... ...

Abstract	Methotrexate (MTX) remains one of the most frequently used anti-metabolite agents in dermatology. MTX is an analog of folate that competitively and irreversibly inhibits dihydrofolate reductase. Oral mucositis is a common side effect of chemotherapy drugs and is characterized by erythema, pain, poor oral intake, pseudomembranous destruction, open ulceration and hemorrhage of the oral mucosa. In this paper, we report a 32-year-old female with a case of mucositis due to MTX intoxication that resulted from an overdose for rheumatoid arthritis. The patient had abdominal pain, vomiting, and nausea. During follow-up, the patient's white blood cell count was found to be 0.9 × 10(9)/L (4-10 × 10(9)/L). The patient developed fever exceeding 40 °C. The patient was consulted to the hematology service. They suggested using granulocyte colony-stimulating factor for febrile neutropenia. On the fifth day of treatment, the white blood cell count reached 5.3 × 10(9)/L and the patient's fever and mucositis started to resolve. Here, we presented a case of hemorrhagic mucositis and febrile neutropenia resulted from high-dose MTX that responded very well to granulocyte colony-stimulating factor treatment and we reviewed the literature.
MeSH term(s)	Adult ; Febrile Neutropenia/chemically induced ; Febrile Neutropenia/drug therapy ; Female ; Granulocyte Colony-Stimulating Factor/therapeutic use ; Hemorrhage/chemically induced ; Hemorrhage/drug therapy ; Humans ; Methotrexate/adverse effects ; Mouth Mucosa/pathology ; Mucositis/chemically induced ; Mucositis/drug therapy
Chemical Substances	Granulocyte Colony-Stimulating Factor (143011-72-7) ; Methotrexate (YL5FZ2Y5U1)
Language	English
Publishing date	2015
Publishing country	England
Document type	Journal Article
ZDB-ID	605635-0
ISSN	1556-9535 ; 1556-9527 ; 0731-3829
ISSN (online)	1556-9535
ISSN	1556-9527 ; 0731-3829
DOI	10.3109/15569527.2014.918139
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Zs.A 1782: Show issues

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Article ; Online: Effect of probiotics on the treatment of children with atopic dermatitis.

Yeşilova, Yavuz / Çalka, Ömer / Akdeniz, Necmettin / Berktaş, Mustafa

Annals of dermatology

2012 Volume 24, Issue 2, Page(s) 189–193

Abstract: Background: Atopic dermatitis, a chronic recurrent disease, is frequently encountered in clinical practice. In the last 30 years, the prevalence of atopic dermatitis has rapidly increased due to industrialization. Therefore, there have been attempts in ... ...

Abstract	Background: Atopic dermatitis, a chronic recurrent disease, is frequently encountered in clinical practice. In the last 30 years, the prevalence of atopic dermatitis has rapidly increased due to industrialization. Therefore, there have been attempts in recent years to find new ways of treating and preventing atopic dermatitis. Objective: In this double-blind, randomized, placebo-controlled study, a combination of Bifidobacterium bifidum, Lactobacillus acidophilus, Lactobacillus casei, and Lactobacillus salivarius strains were evaluated in the treatment of atopic dermatitis in pediatric patients. Methods: Forty pediatric patients (23 males and 17 females) aged 1~13 years were enrolled. One eligible individual who was approached declined to participate. The probiotic group was administered a probiotic complex containing B. bifidum, L. acidophilus, L. casei, and L. salivarius for 8 weeks. The placebo group, on the other hand, was administered skim milk powder and dextrose. All of the parameters including serum cytokines, eosinophil cationic protein), SCORing Atopic Dermatitis (SCORAD) index, and total serum immunoglobulin E (IgE) were measured in both the probiotic group and the placebo group at the end of 8 weeks. Results: Probiotic intervention in pediatric atopic dermatitis patients effectively reduced the SCORAD index and serum cytokines interleukin (IL)-5, IL-6, interferon (IFN)-γ, and total serum IgE levels, but did not reduce levels of serum cytokines IL-2, IL-4, IL-10, ECP, or tumor necrosis factor-α (TNF-α) compared to the placebo group. Conclusion: Our study found probiotics to be effective in reducing atopic dermatitis patients' SCORAD index, serum IL-5, IL-6, IFN-γ, and total serum IgE levels but not effective in reducing serum IL-2, IL-4, IL-10, ECP, or TNF-α levels.
Language	English
Publishing date	2012-04-26
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	1012662-4
ISSN	2005-3894 ; 1013-9087
ISSN (online)	2005-3894
ISSN	1013-9087
DOI	10.5021/ad.2012.24.2.189
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Zs.A 2800: Show issues

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Article ; Online: Phytodermatitis in eastern Turkey: a retrospective, observational study.

Ozkol, Hatice Uce / Calka, Omer / Akdeniz, Necmettin / Pinar, Suleyman Mesut

Dermatitis : contact, atopic, occupational, drug

2014 Volume 25, Issue 3, Page(s) 140–146

Abstract: Background: Plant life is extremely diverse, with a great deal of geographic and seasonal variation. Consequently, the range of reported adverse reactions is large, and there are important differences worldwide in the incidence and prevalence of these ... ...

Abstract	Background: Plant life is extremely diverse, with a great deal of geographic and seasonal variation. Consequently, the range of reported adverse reactions is large, and there are important differences worldwide in the incidence and prevalence of these reactions. Systemic ingestion of some plants containing furocoumarins can cause erythema, edema, vesicle and bulla formation and later hyperpigmentation, after exposure to sunlight. They may at times exhibit clinical manifestations that mimic angioedema, and rarely progress to necrosis. This condition is named phyto-phototoxic reaction. Objective: Our aim was to identify plant dermatitis such as allergic contact dermatitis, irritant contact dermatitis, and phyto-phototoxic dermatitis in eastern Turkey and to add new data to the literature. Methods: Thirty patients diagnosed with plant dermatitis were evaluated retrospectively. The demographic and clinical characteristics of the patients (age, gender, the type of dermatitis, and the name of the causative plant) were recorded. Conclusions: A phyto-phototoxic reaction to Chenopodium album (Chenopodiaceae) developed in 12 cases. Irritant contact dermatitis developed due to Ranunculus kotschyi (Ranunculaceae) in 11 cases. The other plants studied were Malva neglecta Wallr (Malvaceae), Mandragora autumnalis (Solanaceae), Eryngium billardieri (Apiaceae), Ceratocephalus falcatus (Ranunculaceae), Ranunculus damascenus (Ranunculaceae), and Plantago lanceolata (Plantaginaceae).
MeSH term(s)	Acute Disease ; Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/epidemiology ; Dermatitis, Allergic Contact/etiology ; Dermatitis, Photoallergic/diagnosis ; Dermatitis, Photoallergic/epidemiology ; Dermatitis, Photoallergic/etiology ; Dermatitis, Toxicodendron/diagnosis ; Dermatitis, Toxicodendron/epidemiology ; Dermatitis, Toxicodendron/etiology ; Erythema Multiforme/diagnosis ; Erythema Multiforme/epidemiology ; Erythema Multiforme/etiology ; Female ; Humans ; Male ; Middle Aged ; Patch Tests/methods ; Plants/adverse effects ; Retrospective Studies ; Turkey ; Young Adult
Language	English
Publishing date	2014-05
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	2144723-8
ISSN	2162-5220 ; 1532-8163 ; 1710-3568
ISSN (online)	2162-5220 ; 1532-8163
ISSN	1710-3568
DOI	10.1097/DER.0000000000000033
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Zs.A 3680: Show issues

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Article ; Online: Histiocytoid Sweet syndrome.

Bilgili, Serap Gunes / Karadag, Ayse Serap / Calka, Omer / Bulut, Gulay

International journal of dermatology

2014 Volume 53, Issue 2, Page(s) e80–2

MeSH term(s)	Diclofenac/analogs & derivatives ; Female ; Histiocytes/pathology ; Humans ; Male ; Sweet Syndrome/drug therapy ; Sweet Syndrome/pathology
Chemical Substances	Diclofenac (144O8QL0L1)
Language	English
Publishing date	2014-02
Publishing country	England
Document type	Case Reports ; Comment ; Letter
ZDB-ID	412254-9
ISSN	1365-4632 ; 0011-9059 ; 1461-1244
ISSN (online)	1365-4632
ISSN	0011-9059 ; 1461-1244
DOI	10.1111/j.1365-4632.2011.05437.x
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