LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 2 of total 2

Search options

  1. Article ; Online: A simple polystyrene microfluidic device for sensitive and accurate SERS-based detection of infection by malaria parasites.

    Oliveira, Maria João / Caetano, Soraia / Dalot, Ana / Sabino, Filipe / Calmeiro, Tomás R / Fortunato, Elvira / Martins, Rodrigo / Pereira, Eulália / Prudêncio, Miguel / Byrne, Hugh J / Franco, Ricardo / Águas, Hugo

    The Analyst

    2023  Volume 148, Issue 17, Page(s) 4053–4063

    Abstract: Early and accurate detection of infection by pathogenic microorganisms, such as Plasmodium, the causative agent of malaria, is critical for clinical diagnosis and ultimately determines the patient's outcome. We have combined a polystyrene-based ... ...

    Abstract Early and accurate detection of infection by pathogenic microorganisms, such as Plasmodium, the causative agent of malaria, is critical for clinical diagnosis and ultimately determines the patient's outcome. We have combined a polystyrene-based microfluidic device with an immunoassay which utilises Surface-Enhanced Raman Spectroscopy (SERS) to detect malaria. The method can be easily translated to a point-of-care testing format and shows excellent sensitivity and specificity, when compared to the gold standard for laboratorial detection of Plasmodium infections. The device can be fabricated in less than 30 min by direct patterning on shrinkable polystyrene sheets of adaptable three-dimensional microfluidic chips. To validate the microfluidic system, samples of
    MeSH term(s) Humans ; Animals ; Parasites ; Polystyrenes ; Plasmodium falciparum ; Reproducibility of Results ; Malaria/diagnosis ; Malaria, Falciparum/diagnosis ; Plasmodium ; Sensitivity and Specificity ; Lab-On-A-Chip Devices
    Chemical Substances Polystyrenes
    Language English
    Publishing date 2023-08-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d3an00971h
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Stress Induced Mechano-electrical Writing-Reading of Polymer Film Powered by Contact Electrification Mechanism.

    Goswami, Sumita / Nandy, Suman / Calmeiro, Tomás R / Igreja, Rui / Martins, Rodrigo / Fortunato, Elvira

    Scientific reports

    2016  Volume 6, Page(s) 19514

    Abstract: Mechano-electrical writing and reading in polyaniline (PANI) thin film are demonstrated via metal-polymer contact electrification mechanism (CEM). An innovative conception for a non-destructive self-powered writable-readable data sheet is presented which ...

    Abstract Mechano-electrical writing and reading in polyaniline (PANI) thin film are demonstrated via metal-polymer contact electrification mechanism (CEM). An innovative conception for a non-destructive self-powered writable-readable data sheet is presented which can pave the way towards new type of stress induced current harvesting devices. A localized forced deformation of the interface has been enacted by pressing the atomic force microscopic probe against the polymer surface, allowing charge transfer between materials interfaces. The process yields a well-defined charge pattern by transmuting mechanical stress in to readable information. The average of output current increment has been influenced from 0.5 nA to 15 nA for the applied force of 2 nN to 14 nN instead of electrical bias. These results underscore the importance of stress-induced current harvesting mechanism and could be scaled up for charge patterning of polymer surface to writable-readable data sheet. Time evolutional current distribution (TECD) study of the stress-induced patterned PANI surface shows the response of readability of the recorded data with time.
    Language English
    Publishing date 2016-01-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep19514
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top