Article ; Online: New prognostic score for stable coronary disease evaluation.
Arquivos brasileiros de cardiologia
2011 Volume 96, Issue 5, Page(s) 411–418
Abstract: Background: The need to improve the exercise testing accuracy, pushed the development of scores, whose applicability was already broadly recognized.: Objective: Prognostic evaluation of stable coronary disease through a new simplified score.: ... ...
| Abstract | Background: The need to improve the exercise testing accuracy, pushed the development of scores, whose applicability was already broadly recognized. Objective: Prognostic evaluation of stable coronary disease through a new simplified score. Methods: A new score was applied in 372 multivessel coronary patients with preserved ventricular function, 71.8% male, age: 59.5 (± 9.07) years old, randomized to medical treatment, surgery (CABG) or angioplasty (PTCA), with 5 years of follow-up. Cardiovascular death was considered the primary endpoint. Non-fatal myocardial infarction, death and re-intervention were considered for a combined secondary endpoint. The score was based on an equation previously validated, resulting from a sum of one point for: male gender, infarction history, angina, diabetes, insulin use and one point for each decade of life after 40 years old. Positive exercise testing summed one additional point. Results: Thirty six deaths was observed (10 in group PTCA, 15 in CABG and 11 in the clinical group), p = 0.61. We observed 93 combined events: 37 in PTCA group, 23 in CABG and 33 in the clinical group (p = 0.058). 247 patients presented clinical score ≥ 5 points and 216 ≥ 6 points. The cutoff point ≥ 5 or ≥ 6 points identified higher risk, p = 0.015 and p = 0.012, respectively. The survival curve showed a different death incidence after the randomization when score reached 06 points or more (p = 0.07), and a distinct incidence of combined events between the patients with score < 6 and ≥ 6 points (p = 0.02). Conclusion: The new score was consistent for multiarterial stable coronary disease risk stratification. |
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| MeSH term(s) | Age Factors ; Angina Pectoris/epidemiology ; Angioplasty, Balloon, Coronary/mortality ; Angioplasty, Balloon, Coronary/statistics & numerical data ; Coronary Artery Bypass/mortality ; Coronary Artery Bypass/statistics & numerical data ; Coronary Disease/mortality ; Diabetes Mellitus/drug therapy ; Epidemiologic Methods ; Exercise Test/methods ; Female ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Male ; Middle Aged ; Myocardial Infarction/epidemiology ; Myocardial Infarction/mortality ; Prognosis ; Time Factors | |||||
| Chemical Substances | Hypoglycemic Agents ; Insulin | |||||
| Language | Spanish | |||||
| Publishing date | 2011-04-15 | |||||
| Publishing country | Brazil | |||||
| Document type | Journal Article ; Randomized Controlled Trial | |||||
| ZDB-ID | 730261-7 | |||||
| ISSN | 1678-4170 ; 0066-782X | |||||
| ISSN (online) | 1678-4170 | |||||
| ISSN | 0066-782X | |||||
| DOI | 10.1590/s0066-782x2011005000046 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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