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  1. Article ; Online: Diseases during pregnancy in a large unselected South American sample.

    Santos, María Rita / Campaña, Hebe / Heisecke, Silvina / Ratowiecki, Julia / Elías, Darío / Giménez, Lucas / Poletta, Fernando Adrián / Gili, Juan / Uranga, Rocío / Cosentino, Viviana / Krupitzki, Hugo / Rittler, Mónica / Camelo, Jorge López

    Revista brasileira de epidemiologia = Brazilian journal of epidemiology

    2022  Volume 25, Page(s) e220043

    Abstract: Objective: Our aim was to describe the prevalence of diseases during pregnancy and the association between fetal exposure to the most frequent maternal diseases and the risk of preterm (PTB) and/or small for gestational age (SGA) newborns in an ... ...

    Abstract Objective: Our aim was to describe the prevalence of diseases during pregnancy and the association between fetal exposure to the most frequent maternal diseases and the risk of preterm (PTB) and/or small for gestational age (SGA) newborns in an unselected sample of women who gave birth in South American countries.
    Methods: We conducted a descriptive, cross-sectional study including 56,232 mothers of non-malformed infants born between 2002 and 2016, using data from the Latin American Collaborative Study of Congenital Malformations (ECLAMC). Diseases with higher- than-expected PTB/SGA frequencies were identified. Odds ratios of confounding variables for diseases and birth outcomes were calculated with a multivariable logistic regression.
    Results: Of the 14 most reported diseases, hypertension, genitourinary infection, epilepsy, hypothyroidism, diabetes, and HIV/AIDS showed higher PTB and/or SGA frequencies. Advanced and low maternal age, previous fetal loss, low socioeconomic level, and African-American ancestry were associated with PTB, while advanced maternal age, primigravidity, previous fetal loss, low socioeconomic level, and African-American ancestry were associated with SGA. After adjusting for the associated variables, the identified illnesses maintained their association with PTB and all, except epilepsy, with SGA.
    Conclusion: The description of an unselected population of mothers allowed identifying the most frequent diseases occurring during gestation and their impact on pregnancy outcomes. Six diseases were associated with PTB and two with SGA newborns. To the best of our knowledge, there are no similar reports about women not intentionally selected by specific diseases during pregnancy in South American populations.
    MeSH term(s) Infant, Newborn ; Female ; Humans ; Pregnancy ; Cross-Sectional Studies ; Brazil
    Language English
    Publishing date 2022-12-05
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2183366-7
    ISSN 1980-5497 ; 1980-5497
    ISSN (online) 1980-5497
    ISSN 1980-5497
    DOI 10.1590/1980-549720220043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Lethality of Birth Defects in Live Born Infants Categorized by Gestational Age and Birth Weight.

    Rittler, Monica / Campaña, Hebe / Heisecke, Silvina / Ratowiecki, Julia / Elias, Dario / Gimenez, Lucas / Poletta, Fernando A / Gili, Juan / Pawluk, Mariela / Santos, Maria Rita / Uranga, Rocio / Cosentino, Viviana / Camelo, Jorge Lopez

    American journal of perinatology

    2021  Volume 40, Issue 13, Page(s) 1406–1412

    Abstract: Objective: This study aimed to describe lethality of birth defects (BDs) in newborns categorized by gestational age and birth weight and to identify BDs associated with prematurity.: Study design: Live born infants (: Results: Overall fewer ... ...

    Abstract Objective: This study aimed to describe lethality of birth defects (BDs) in newborns categorized by gestational age and birth weight and to identify BDs associated with prematurity.
    Study design: Live born infants (
    Results: Overall fewer malformed than nonmalformed infants were of adequate growth, while the opposite occurred in the preterm and SGA categories where gastroschisis and esophageal atresia were among the most outstanding defects. For most severe BDs, the early neonatal death rate was higher than control values in all categories; for mild defects, except cleft lip in the preterm category, they did not differ. Diaphragmatic hernia showed the highest lethality values, while those of spina bifida were among the lowest. Talipes, hypospadias, and septal heart defects were mild defects significantly associated with prematurity.
    Conclusion: Although reasons, such as induced preterm delivery of fetuses with certain anomalies, could partially account for their high prematurity rates, susceptibility to preterm birth might exist through underlying mechanisms related with the defects. The identification of BDs associated with prematurity should serve to improve measures that prevent preterm birth especially of fetuses at risk.
    Key points: · Some BDs predispose to prematurity.. · Prematurity is an additional risk factor for mortality in infants with mild defects.. · Lethality values should be adjusted by gestational age and birth weight..
    MeSH term(s) Male ; Female ; Infant, Newborn ; Infant ; Humans ; Pregnancy ; Birth Weight ; Gestational Age ; Premature Birth ; Infant, Premature ; Infant, Small for Gestational Age ; Fetal Growth Retardation
    Language English
    Publishing date 2021-10-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/s-0041-1735867
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1929: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Gastroschisis prevalence patterns in 27 surveillance programs from 24 countries, International Clearinghouse for Birth Defects Surveillance and Research, 1980-2017.

    Feldkamp, Marcia L / Canfield, Mark A / Krikov, Sergey / Prieto-Merino, David / Šípek, Antonin / LeLong, Nathalie / Amar, Emmanuelle / Rissmann, Anke / Csaky-Szunyogh, Melinda / Tagliabue, Giovanna / Pierini, Anna / Gatt, Miriam / Bergman, Jorieke E H / Szabova, Elena / Bermejo-Sánchez, Eva / Tucker, David / Dastgiri, Saeed / Bidondo, María Paz / Canessa, Aurora /
    Zarante, Ignacio / Hurtado-Villa, Paula / Martinez, Laura / Mutchinick, Osvaldo M / Camelo, Jorge Lopez / Benavides-Lara, Adriana / Thomas, Mary Ann / Liu, Shiliang / Nembhard, Wendy N / Gray, Elizabeth B / Nance, Amy E / Mastroiacovo, Pierpaolo / Botto, Lorenzo D

    Birth defects research

    2024  Volume 116, Issue 2, Page(s) e2306

    Abstract: Background: Gastroschisis is a serious birth defect with midgut prolapse into the amniotic cavity. The objectives of this study were to evaluate the prevalence and time trends of gastroschisis among programs in the International Clearinghouse for Birth ... ...

    Abstract Background: Gastroschisis is a serious birth defect with midgut prolapse into the amniotic cavity. The objectives of this study were to evaluate the prevalence and time trends of gastroschisis among programs in the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR), focusing on regional variations and maternal age changes in the population.
    Methods: We analyzed data on births from 1980 to 2017 from 27 ICBDSR member programs, representing 24 countries and three regions (Europe
    Results: Overall, gastroschisis occurred in 1 of every 3268 births (3.06 per 10,000 births; 95% confidence intervals [CI]: 3.01, 3.11), with marked regional variation. European
    Conclusions: Gastroschisis prevalence increased over time in 61% of participating programs, and the highest increase in prevalence was observed among the youngest women. Additional inquiry will help to assess the impact of the changing maternal age proportions in the birth population on gastroschisis prevalence.
    MeSH term(s) Pregnancy ; Infant, Newborn ; Female ; Humans ; Gastroschisis/epidemiology ; Prevalence ; Stillbirth ; Maternal Age ; Hernia, Umbilical/epidemiology ; Limb Deformities, Congenital
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2104792-3
    ISSN 2472-1727
    ISSN (online) 2472-1727
    DOI 10.1002/bdr2.2306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 749: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Lethality of Birth Defects in Live Born Infants Categorized by Gestational Age and Birth Weight

    Rittler, Monica / Campaña, Hebe / Heisecke, Silvina / Ratowiecki, Julia / Elias, Dario / Gimenez, Lucas / Poletta, Fernando A. / Gili, Juan / Pawluk, Mariela / Santos, Maria Rita / Uranga, Rocio / Cosentino, Viviana / Camelo, Jorge Lopez

    American Journal of Perinatology

    2021  Volume 40, Issue 13, Page(s) 1406–1412

    Abstract: Objective: This study aimed to describe lethality of birth defects (BDs) in newborns categorized by gestational age and birth weight and to identify BDs associated with prematurity.: Study Design: Live born infants ( n  = 16,452) with isolated BDs ... ...

    Abstract Objective: This study aimed to describe lethality of birth defects (BDs) in newborns categorized by gestational age and birth weight and to identify BDs associated with prematurity.
    Study Design: Live born infants ( n  = 16,452) with isolated BDs classified by severity, and 42,511 healthy controls were assigned to categories: adequate growth, preterm, or small for gestational age (SGA). Proportion of cases and BDs' lethality rates were obtained by category and compared with controls.
    Results: Overall fewer malformed than nonmalformed infants were of adequate growth, while the opposite occurred in the preterm and SGA categories where gastroschisis and esophageal atresia were among the most outstanding defects. For most severe BDs, the early neonatal death rate was higher than control values in all categories; for mild defects, except cleft lip in the preterm category, they did not differ. Diaphragmatic hernia showed the highest lethality values, while those of spina bifida were among the lowest. Talipes, hypospadias, and septal heart defects were mild defects significantly associated with prematurity.
    Conclusion: Although reasons, such as induced preterm delivery of fetuses with certain anomalies, could partially account for their high prematurity rates, susceptibility to preterm birth might exist through underlying mechanisms related with the defects. The identification of BDs associated with prematurity should serve to improve measures that prevent preterm birth especially of fetuses at risk.
    Key Points: Some BDs predispose to prematurity. Prematurity is an additional risk factor for mortality in infants with mild defects. Lethality values should be adjusted by gestational age and birth weight.
    Keywords Lethality ; birth defects ; prematurity ; birth weight ; risk ; ECLAMC
    Language English
    Publishing date 2021-10-11
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/s-0041-1735867
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1929: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Linking childhood poverty and cognition: environmental mediators of non-verbal executive control in an Argentine sample.

    Lipina, Sebastián / Segretin, Soledad / Hermida, Julia / Prats, Lucía / Fracchia, Carolina / Camelo, Jorge López / Colombo, Jorge

    Developmental science

    2013  Volume 16, Issue 5, Page(s) 697–707

    Abstract: Tests of attentional control, working memory, and planning were administered to compare the non-verbal executive control performance of healthy children from different socioeconomic backgrounds. In addition, mediations of several sociodemographic ... ...

    Abstract Tests of attentional control, working memory, and planning were administered to compare the non-verbal executive control performance of healthy children from different socioeconomic backgrounds. In addition, mediations of several sociodemographic variables, identified in the literature as part of the experience of child poverty, between socioeconomic status and cognitive performance were assessed. Results show: (1) significant differences in performance between groups in most dependent variables analyzed - however, not in all variables associated with attentional control domains; (2) significant indirect effects of literacy activities on working memory and fluid processing domains, as well as computer resources effects on fluid processing; and (3) marginal indirect effects of computer resources on attentional control and working memory domains. These findings extend analysis of the impact of poverty on the development of executive control, through information based on the assessment of combined neurocognitive paradigms and the identification of specific environmental mediators.
    MeSH term(s) Analysis of Variance ; Argentina ; Attention/physiology ; Child ; Cognition/physiology ; Demography ; Executive Function/physiology ; Female ; Humans ; Male ; Memory, Short-Term/physiology ; Poverty/psychology ; Psychomotor Performance/physiology
    Language English
    Publishing date 2013-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2023952-X
    ISSN 1467-7687 ; 1363-755X
    ISSN (online) 1467-7687
    ISSN 1363-755X
    DOI 10.1111/desc.12080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Random inbreeding, isonymy, and population isolates in Argentina.

    Dipierri, José / Rodríguez-Larralde, Alvaro / Barrai, Italo / Camelo, Jorge López / Redomero, Esperanza Gutiérrez / Rodríguez, Concepción Alonso / Ramallo, Virginia / Bronberg, Rubén / Alfaro, Emma

    Journal of community genetics

    2014  Volume 5, Issue 3, Page(s) 241–248

    Abstract: Population isolates are an important tool in identifying and mapping genes of Mendelian diseases and complex traits. The geographical identification of isolates represents a priority from a genetic and health care standpoint. The purpose of this study is ...

    Abstract Population isolates are an important tool in identifying and mapping genes of Mendelian diseases and complex traits. The geographical identification of isolates represents a priority from a genetic and health care standpoint. The purpose of this study is to analyze the spatial distribution of consanguinity by random isonymy (F ST) in Argentina and its relationship with the isolates previously identified in the country. F ST was estimated from the surname distribution of 22.6 million electors registered for the year 2001 in the 24 provinces, 5 geographical regions, and 510 departments of the country. Statistically significant spatial clustering of F ST was determined using the SaTScan V5.1 software. F ST exhibited a marked regional and departamental variation, showing the highest values towards the North and West of Argentina. The clusters of high consanguinity by random isonymy followed the same distribution. Recognized Argentinean genetic isolates are mainly localized at the north of the country, in clusters of high inbreeding. Given the availability of listings of surnames in high-capacity storage devices for different countries, estimating F ST from them can provide information on inbreeding for all levels of administrative subdivisions, to be used as a demographic variable for the identification of isolates within the country for public health purposes.
    Language English
    Publishing date 2014-02-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2543127-4
    ISSN 1868-6001 ; 1868-310X
    ISSN (online) 1868-6001
    ISSN 1868-310X
    DOI 10.1007/s12687-013-0181-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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