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  1. AU="Campbell-Bell, Cherith M"
  2. AU="Bayne, Max"
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  1. Article ; Online: Pulsatile tympanic membrane displacement is associated with cognitive score in healthy subjects.

    Birch, Anthony A / El-Bouri, Wahbi K / Marchbanks, Robert J / Moore, Laura A / Campbell-Bell, Cherith M / Kipps, Christopher M / Bulters, Diederik O

    Cerebral circulation - cognition and behavior

    2022  Volume 3, Page(s) 100132

    Abstract: To test the hypothesis that pulsing of intracranial pressure has an association with cognition, we measured cognitive score and pulsing of the tympanic membrane in 290 healthy subjects. This hypothesis was formed on the assumptions that large ... ...

    Abstract To test the hypothesis that pulsing of intracranial pressure has an association with cognition, we measured cognitive score and pulsing of the tympanic membrane in 290 healthy subjects. This hypothesis was formed on the assumptions that large intracranial pressure pulses impair cognitive performance and tympanic membrane pulses reflect intracranial pressure pulses. 290 healthy subjects, aged 20-80 years, completed the Montreal Cognitive Assessment Test. Spontaneous tympanic membrane displacement during a heart cycle was measured from both ears in the sitting and supine position. We applied multiple linear regression, correcting for age, heart rate, and height, to test for an association between cognitive score and spontaneous tympanic membrane displacement. Significance was set at
    Language English
    Publishing date 2022-02-28
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-2450
    ISSN (online) 2666-2450
    DOI 10.1016/j.cccb.2022.100132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reference intervals for the evoked tympanic membrane displacement measurement: a non-invasive measure of intracranial pressure.

    Campbell-Bell, Cherith M / Birch, Anthony A / Vignali, Dario / Bulters, Diederik / Marchbanks, Robert J

    Physiological measurement

    2018  Volume 39, Issue 1, Page(s) 15008

    Abstract: Objective: Evoked tympanic membrane displacement (TMD) is a non-invasive technique for assessing intracranial pressure (ICP). The aim of this study was to define reference intervals (RIs) in the healthy population.: Approach: Measurements were made ... ...

    Abstract Objective: Evoked tympanic membrane displacement (TMD) is a non-invasive technique for assessing intracranial pressure (ICP). The aim of this study was to define reference intervals (RIs) in the healthy population.
    Approach: Measurements were made in 154 healthy adults. Results were quantified by V
    Main results: The range in which 95% of scores fall is  -283 to 722 nl (M  =  132 nl) left sitting, -232 to 623 nl (M  =  97 nl) right sitting, -543 to 717 nl (M  =  37 nl) left supine and  -584 to 504 nl (M  =  -15 nl) right supine. No significant difference was seen between the left and right ears in the sitting position; a significant difference was seen in the supine position. A significant effect of posture was seen for both the left and right ears. Postural changes indicated pressure transfer between the CSF and perilymph more often in the right ear (75.3%) than the left (61.9%). Pressure transfer could not be assumed in either ear for 13.4% of participants.
    Significance: We present the largest dataset of evoked TMD in healthy individuals and the first set of RIs for V
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Female ; Healthy Volunteers ; Humans ; Intracranial Pressure ; Male ; Middle Aged ; Posture ; Reference Values ; Tympanic Membrane/physiology ; Young Adult
    Language English
    Publishing date 2018-01-31
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1149545-5
    ISSN 1361-6579 ; 0967-3334
    ISSN (online) 1361-6579
    ISSN 0967-3334
    DOI 10.1088/1361-6579/aaa1d3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Does the Variability of Evoked Tympanic Membrane Displacement Data (V

    Sharif, Sammy J / Campbell-Bell, Cherith M / Bulters, Diederik O / Marchbanks, Robert J / Birch, Anthony A

    Acta neurochirurgica. Supplement

    2018  Volume 126, Page(s) 103–106

    Abstract: Objectives: Evoked tympanic membrane displacement (TMD) measurements, quantified by V : Materials and methods: Spontaneous and evoked TMD data from each ear in the sitting and supine position were recorded from 100 healthy volunteers using the MMS-14 ...

    Abstract Objectives: Evoked tympanic membrane displacement (TMD) measurements, quantified by V
    Materials and methods: Spontaneous and evoked TMD data from each ear in the sitting and supine position were recorded from 100 healthy volunteers using the MMS-14 CCFP analyser. ECG was also recorded to identify each heartbeat. Using bespoke software written in Matlab, spontaneous data were analysed to produce average pulse amplitude (PA) waveforms and evoked data were analysed to calculate average V
    Results: There was a strong positive correlation between PA and V
    Conclusion: This study shows that large V
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Electrocardiography ; Female ; Healthy Volunteers ; Humans ; Intracranial Pressure/physiology ; Male ; Middle Aged ; Posture ; Pulse ; Reflex, Acoustic/physiology ; Reproducibility of Results ; Tympanic Membrane/physiology ; Young Adult
    Language English
    Publishing date 2018
    Publishing country Austria
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 0065-1419
    ISSN 0065-1419
    DOI 10.1007/978-3-319-65798-1_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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