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Article ; Online: Lymphatic Microsurgical Preventive Healing Approach for the Primary Prevention of Lymphedema: A 4-Year Follow-Up.

Campisi, Corrado C / Scarabosio, Anna / Campisi, Corradino

2023 Volume 153, Issue 2, Page(s) 490e–491e

MeSH term(s)	Humans ; Follow-Up Studies ; Lymphedema/etiology ; Lymphedema/prevention & control ; Lymphedema/surgery ; Lymphatic Vessels/surgery ; Primary Prevention ; Microsurgery ; Lymphatic System ; Anastomosis, Surgical
Language	English
Publishing date	2023-05-26
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000010764
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Zs.MO 293: Show issues

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Article: Comments on Algorithmic Approach to the Lymphatic Leak after Vascular Reconstruction: A Systematic Review.

Watfa, William / Sörelius, Karl / Campisi, Corrado / Oranges, Carlo M / Raffoul, Wassim / di Summa, Pietro G

Archives of plastic surgery

2023 Volume 50, Issue 1, Page(s) 119–120

Language	English
Publishing date	2023-02-06
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2694943-X
ISSN	2234-6171 ; 2234-6163
ISSN (online)	2234-6171
ISSN	2234-6163
DOI	10.1055/s-0043-1761160
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Article: A Rare Immune-Related Mesenteric and retroperitoneal serositis in a Multi-Refractory Hodgkin Lymphoma Patient Successfully Treated with Chylolymphostatic Surgery.

D'Addona, Matteo / Pezzullo, Luca / Campisi, Corradino / Campisi, Corrado Cesare / Giudice, Valentina / Ciccone, Vincenzo / Guariglia, Roberto / Serio, Bianca / Selleri, Carmine

Mediterranean journal of hematology and infectious diseases

2023 Volume 15, Issue 1, Page(s) e2023063

Language	English
Publishing date	2023-11-01
Publishing country	Italy
Document type	Journal Article ; Comment
ZDB-ID	2674750-9
ISSN	2035-3006
ISSN	2035-3006
DOI	10.4084/MJHID.2023.063
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Article: Comments on Algorithmic Approach to the Lymphatic Leak after Vascular Reconstruction: A Systematic Review

Watfa, William / Sörelius, Karl / Campisi, Corrado / Oranges, Carlo M. / Raffoul, Wassim / di Summa, Pietro G.

Archives of Plastic Surgery

2023 Volume 50, Issue 01, Page(s) 119–120

Language	English
Publishing date	2023-01-01
Publisher	Thieme Medical Publishers, Inc.
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	2694943-X
ISSN	2234-6171 ; 2234-6163 ; 2234-6171
ISSN (online)	2234-6171
ISSN	2234-6163 ; 2234-6171
DOI	10.1055/s-0043-1761160
Database	Thieme publisher's database

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Article ; Online: Celocentesis for Early Prenatal Diagnosis in Couples at-Risk for β-Thalassemia and Sicilian (δβ)

Giambona, Antonino / Leto, Filippo / Cassarà, Filippo / Tartaglia, Viviana / Campisi, Rosario / Campisi, Corrado / Cigna, Valentina / Mugavero, Elena / Cucinella, Gaspare / Orlandi, Emanuela / Picciotto, Francesco / Maggio, Aurelio / Vinciguerra, Margherita

Hemoglobin

2023 Volume 46, Issue 6, Page(s) 297–302

Abstract: The procedures commonly used for prenatal diagnosis (PND) of thalassemia are villocentesis or amniocentesis, respectively, at the 11th and 16th weeks of gestation. Their main limitation is essentially due to the late gestation week in which diagnosis is ... ...

Abstract	The procedures commonly used for prenatal diagnosis (PND) of thalassemia are villocentesis or amniocentesis, respectively, at the 11th and 16th weeks of gestation. Their main limitation is essentially due to the late gestation week in which diagnosis is performed. The celomic cavity is accessible between the 7th and 9th weeks of gestation and it has been demonstrated that it contains embryonic erythroid precursor cells as a source of fetal DNA for earlier invasive PND of thalassemia and other monogenic diseases. In this study, we report the use of celomatic fluids obtained from nine women with high-risk pregnancies for Sicilian (δβ)
MeSH term(s)	Female ; Humans ; Pregnancy ; beta-Thalassemia ; Thalassemia ; Prenatal Diagnosis ; Early Diagnosis ; Fetus
Language	English
Publishing date	2023-02-21
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	750615-6
ISSN	1532-432X ; 0363-0269
ISSN (online)	1532-432X
ISSN	0363-0269
DOI	10.1080/03630269.2023.2167659
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Zs.A 1345: Show issues

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Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Bipedicled distally based medial plantar artery perforator flap for forefoot reconstruction: A case report.

Guillier, David / Campisi, Corrado / Krähenbühl, Swen M / Raffoul, Wassim / di Summa, Pietro G

Microsurgery

2020 Volume 40, Issue 4, Page(s) 497–500

Abstract: Reconstruction of soft-tissue defects in the foot weight-bearing area should encompass sensate and robust skin. Regarding forefoot defects, distally based medial plantar artery (MPA) flap is an ideal option. However, considering variation of the terminal ...

Abstract	Reconstruction of soft-tissue defects in the foot weight-bearing area should encompass sensate and robust skin. Regarding forefoot defects, distally based medial plantar artery (MPA) flap is an ideal option. However, considering variation of the terminal branches of the MPA, reverse flow flaps can be unreliable with an increasing risk of venous congestion or insufficient arterial flow. In this report, we present a case of the use of reverse flow MPA flaps with dual flow vascularization. The patient was a 37-year-old female who presented a 7 × 3 cm soft-tissue defect of the right forefoot after wide local excision following melanoma. Reconstruction happened with a perforator distally based bipedicled flap (8 × 4 cm) on the MPA though keeping an enhanced vascularization through both superficial (sMPA) and deep (dMPA) medial plantar arteries. Donor site was closed with skin graft. Patient was discharged from hospital at postoperative Day 10 and healed uneventfully with progressive start walk was possible again. A full weight bearing with normal shoes was possible after 8 weeks. Good healing and no functional impairment were present after 9 months of follow-up. We believe this dual vascularization concept may be adopted when possible to improve the overall circulation of the flap and to prevent risks of vascular insufficiency or vein congestion.
MeSH term(s)	Adult ; Female ; Foot ; Humans ; Melanoma/pathology ; Melanoma/surgery ; Perforator Flap ; Reconstructive Surgical Procedures/methods ; Skin Neoplasms/pathology ; Skin Neoplasms/surgery
Language	English
Publishing date	2020-04-03
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	605524-2
ISSN	1098-2752 ; 0738-1085
ISSN (online)	1098-2752
ISSN	0738-1085
DOI	10.1002/micr.30583
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Zs.A 1570: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Role of the Cadaver Lab in Lymphatic Microsurgery Education: Validation of a New Training Model.

Jiga, Lucian P / Campisi, Corrado C / Jandali, Zaher / Ryan, Melissa / Maruccia, Michele / Santecchia, Luigino / Cherubino, Mario / Georgiadis, Janniko

Journal of investigative surgery : the official journal of the Academy of Surgical Research

2021 Volume 35, Issue 4, Page(s) 758–767

Abstract: Background: Microsurgical transplantation of vascularized lymph nodes (VLNT) or lymphatic vessels (VLVT) alongside derivative lymphaticovenous procedures are promising approaches for treatment of lymphedema. However, clinically relevant training models ... ...

Abstract	Background: Microsurgical transplantation of vascularized lymph nodes (VLNT) or lymphatic vessels (VLVT) alongside derivative lymphaticovenous procedures are promising approaches for treatment of lymphedema. However, clinically relevant training models for mastering these techniques are still lacking. Here we describe a new training model in human cadaver and validate its use as training tool for microsurgical lymphatic reconstruction. Methods: 10 surgeons with previous exposure to microsurgery were trained in a controlled environment. Lymphatic vessel mapping and dissection in 4 relevant body regions, harvesting of five different VLNTs and one VLVT were performed in 5 fresh-frozen cadavers. The number of lymphatic vessels and lymph nodes for each VLNT were recorded. Finally, the efficacy of this model as training tool was validated using the Dundee Ready Education Environment Measure (DREEM). Results: The average cumulative DREEM score over each category was 30,75 (max = 40) while individual scoring for each relevant category revealed highly positive ratings from the perspective of teaching (39,3), training 40,5 (max = 48) and self perception of the training 30,5 (max = 32) from all participants. The groin revealed the highest number of lymphatic vessels (3.2 ± 0.29 Conclusions: This human cadaver model represents a new, reproducible "all-in-one" tool for effective training in lymphatic microsurgery. Its unique diligence in accurately reproducing human lymphatic anatomy, should make this model worth considering for each microsurgeon willing to approach lymphatic reconstruction.
MeSH term(s)	Anastomosis, Surgical/methods ; Cadaver ; Humans ; Lymph Nodes/surgery ; Lymphatic Vessels/pathology ; Lymphatic Vessels/surgery ; Lymphedema/pathology ; Lymphedema/surgery ; Microsurgery/methods
Language	English
Publishing date	2021-06-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	639444-9
ISSN	1521-0553 ; 0894-1939
ISSN (online)	1521-0553
ISSN	0894-1939
DOI	10.1080/08941939.2021.1937756
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Zs.A 2364: Show issues

Location:
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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: A Systematic Review of Outcomes After Genital Lymphedema Surgery: Microsurgical Reconstruction Versus Excisional Procedures.

Guiotto, Martino / Bramhall, Russell J / Campisi, Corrado / Raffoul, Wassim / di Summa, Pietro Giovanni

Annals of plastic surgery

2019 Volume 83, Issue 6, Page(s) e85–e91

Abstract: Introduction: Genital lymphedema (GL) surgery can be either palliative or functional. Palliative procedures involve excision of the affected tissue and reconstruction by either local flaps or skin grafts. Reconstructive procedures aim to restore ... ...

Abstract	Introduction: Genital lymphedema (GL) surgery can be either palliative or functional. Palliative procedures involve excision of the affected tissue and reconstruction by either local flaps or skin grafts. Reconstructive procedures aim to restore lymphatic flow through microsurgical lymphaticovenous anastomoses (LVAs). This systematic analysis of outcomes and complication rates aims to compare outcomes between these surgical treatment options for GL. Methods: A systematic review of the PubMed database was performed with the following search algorithm: (lymphorrhea or lymphedema) and (genital or scrotal or vulvar) and (microsurgery or "surgical treatment"), evaluating outcomes, and complications after surgical treatment of GL. Results: Twenty studies published between 1980 and 2016 met the inclusion criteria (total, 151 patients). Three main surgical treatments for GL were identified. Surgical resection and primary closure or skin graft was the most common procedure (46.4%) with a total complication rate of 10%. Surgical resection and flap reconstruction accounted for 39.1% of the procedures with an overall complication rate of 54.2%. Lympho venous shunt (LVA) procedures (14.5%) had a total complication rate of 9%. Conclusions: This review demonstrates a lack of consensus in both the preoperative assessment and surgical management of GL. Patients receiving excisional procedures tended to be later stage lymphedema. Patients in the excision and flap reconstruction group seemed to have the highest complication rates. Microsurgical LVAs may represent an alternative approach to GL, either alone or in combination with traditional procedures.
MeSH term(s)	Adult ; Anastomosis, Surgical/methods ; Female ; Follow-Up Studies ; Genital Diseases, Female/diagnosis ; Genital Diseases, Female/surgery ; Genital Diseases, Male/diagnosis ; Genital Diseases, Male/surgery ; Humans ; Lymphedema/diagnosis ; Lymphedema/surgery ; Male ; Microsurgery/methods ; Reconstructive Surgical Procedures/methods ; Surgical Flaps/transplantation ; Wound Healing/physiology
Language	English
Publishing date	2019-05-24
Publishing country	United States
Document type	Journal Article ; Systematic Review
ZDB-ID	423835-7
ISSN	1536-3708 ; 0148-7043
ISSN (online)	1536-3708
ISSN	0148-7043
DOI	10.1097/SAP.0000000000001875
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Zs.A 1419: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Fibro-Lipo-Lymph-Aspiration With a Lymph Vessel Sparing Procedure to Treat Advanced Lymphedema After Multiple Lymphatic-Venous Anastomoses: The Complete Treatment Protocol.

Campisi, Corrado Cesare / Ryan, Melissa / Boccardo, Francesco / Campisi, Corradino

Annals of plastic surgery

2017 Volume 78, Issue 2, Page(s) 184–190

Abstract: Background: In lymphedema, excess adipose tissue occurs with progression of the disease because of chronic lymph stasis, impeding lymphatic flow. Recently, liposuction has been used as a less-invasive procedure to remove this excess tissue. Given the ... ...

Abstract	Background: In lymphedema, excess adipose tissue occurs with progression of the disease because of chronic lymph stasis, impeding lymphatic flow. Recently, liposuction has been used as a less-invasive procedure to remove this excess tissue. Given the existing poor lymph drainage in patients with lymphatic diseases, extra caution should be taken to avoid damaging lymphatic vessels during liposuction. We developed a new technique (Fibro-Lipo-Lymph-Aspiration with a Lymph Vessel Sparing Procedure [FLLA-LVSP]) to improve chronic swelling in patients with advanced lymphedema. The FLLA-LSVP highlights the superficial lymphatic pathways in the treated limb. This visibility allows surgeons to avoid these pathways, while removing the maximum amount of excess tissue. Method: One hundred forty-six patients with primary or secondary lymphedema that had already been treated by lymphatic microsurgery, in Genoa, Italy, were included in this retrospective study. All patients had residual fibrotic/adipose tissue, resistant to conservative treatments. Indocyanine green fluorescent dye and Blue Patent Violet dye were injected laterally/medially to the main superficial veins at the wrist/ankle of the limb to be treated. Using a photodynamic camera, the superficial lymphatic network was made visible and sketched onto the skin in indelible ink. After the microlymphography, the excess adipose tissue was carefully aspirated. Preoperative and postoperative excess limb volume was calculated using circumferential measurements and the formula of a frustum. Results: For the upper limb, 0.80 L, on average, and 2.42 L for the lower limb were removed with the FLLA-LVSP. For the upper limb, there was an average presurgery excess volume of 20.19%, which reduced to 2.68% after the FLLA-LVSP (Z score = -6.90, P < 0.001). Similarly, for the lower limb, there was an average presurgery excess limb volume of 21.24% and a reduction to 2.64% postoperatively (Z score = -3.57, P < 0.01). Immediate postoperative microlymphography and Blue Patent Violet test confirmed no lymphatic complications. No episodes of postoperative infection occurred. Conclusions: The FLLA-LVSP is efficient. An entire leg can be completed within 90 minutes. Recovery time is short, and cosmetic results are immediate. More importantly, the removal of excess tissue is completed without further damage to lymphatic vessels. When used after microsurgery, FLLA-LVSP offers the possibility of removing almost all obstacles to lymphatic flow.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Anastomosis, Surgical ; Female ; Follow-Up Studies ; Humans ; Lipectomy/methods ; Lymphatic Vessels/surgery ; Lymphedema/surgery ; Male ; Microsurgery/methods ; Middle Aged ; Reoperation ; Retrospective Studies ; Treatment Outcome ; Veins/surgery
Language	English
Publishing date	2017-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	423835-7
ISSN	1536-3708 ; 0148-7043
ISSN (online)	1536-3708
ISSN	0148-7043
DOI	10.1097/SAP.0000000000000853
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Zs.A 1419: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Lymphatic Leaks of the Thigh and Inguinal Region: Combined Plastic Surgery Approaches for an Effective Treatment Algorithm.

Watfa, William / Campisi, Corrado / Ryan, Melissa / Matter, Maurice / Cherix, Stephane / Sörelius, Karl / Raffoul, Wassim / di Summa, Pietro Giovanni

Annals of plastic surgery

2020 Volume 85, Issue 6, Page(s) 661–667

Abstract: Background: Surgical procedures interfering with the draining nodes in the inguinal region carry the intrinsic risk of lymphatic complications. Lesions of the inguinal lymphatic network can lead to lymphocele or lymphocutaneous fistulas and can ... ...

Abstract	Background: Surgical procedures interfering with the draining nodes in the inguinal region carry the intrinsic risk of lymphatic complications. Lesions of the inguinal lymphatic network can lead to lymphocele or lymphocutaneous fistulas and can eventually be associated to limb lymphedema with consequent high morbidity. Objectives: This article describes a new surgical algorithm based on wound properties to properly address lymphatic complications of the inguinal area. Based on our experience, surgical solutions ranged from selective lymphatic vessel ligation to microsurgical lymphatic fistula treatment and free tissue transfer. Methods: Fourteen consecutive patients underwent surgery in our department following failed attempts to address persistent lymphatic leaks. Patient characteristics such as smoking, previous surgeries, comorbidities, and wound properties were considered. Identification of the leak was performed using blue patent dye and indocyanine green fluorescence. Surgical reconstruction occurred, according to our algorithm. Results: Lymphatic leaks were visualized in 11 of 14 patients. Direct closure of the wound after leak ligation could be performed in 4 of 14 patients. Multilymphatic into vein anastomosis was performed in 3 of 14 patients, and the remaining patients benefited from flap surgery based on the wound defects. All 14 patients had successful outcomes (100%) with early drain removal (average, 6 [SD, 6] days) and definitive wound healing 2 weeks postoperatively. After a mean follow-up of 12 (SD, 2.9) months, no clinical infection, lymphatic complication, or wound breakdown occurred. One patient had a partial recurrence that did not require surgical intervention. Conclusions: A stepwise approach, combining lymphatic surgery principles and plastic surgery flap techniques, can lead to an effective treatment algorithm where surgical options are wound tailored to guarantee the best functional outcomes.
MeSH term(s)	Algorithms ; Humans ; Lymphatic Vessels/surgery ; Neoplasm Recurrence, Local ; Surgery, Plastic ; Thigh
Language	English
Publishing date	2020-03-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	423835-7
ISSN	1536-3708 ; 0148-7043
ISSN (online)	1536-3708
ISSN	0148-7043
DOI	10.1097/SAP.0000000000002310
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1419: Show issues

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ab Jg. 2022: Lesesaal (EG)

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