Article ; Online: Anti-Inflammatory and Histological Analysis of Skin Wound Healing through Topical Application of Mexican Propolis.
International journal of molecular sciences
2023 Volume 24, Issue 14
Abstract: Skin wound healing is a complex biochemical process of tissue repair and remodeling in response to injury. Currently, the drugs used to improve the healing process are inaccessible to the population, are costly, and have side effects, making the search ... ...
Abstract | Skin wound healing is a complex biochemical process of tissue repair and remodeling in response to injury. Currently, the drugs used to improve the healing process are inaccessible to the population, are costly, and have side effects, making the search for new treatment alternatives necessary. Propolis is a natural product produced by bees that is widely recognized and used in folk medicine for its multiple biomedical activities. However, therapeutic information regarding Mexican propolis is limited. This study aimed to evaluate the wound-healing effect of the Chihuahua ethanolic extract of propolis (ChEEP). Macroscopic and histological analyses were performed using a mouse wound-healing model. The topic acute toxicity assay showed that propolis at 10% w/v had no toxic effects. ChEEP has antibacterial activity against the Gram-positive bacteria |
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MeSH term(s) | Animals ; Propolis/pharmacology ; Propolis/therapeutic use ; Wound Healing ; Anti-Bacterial Agents/therapeutic use ; Disease Models, Animal ; Ethanol/pharmacology ; Anti-Inflammatory Agents/pharmacology |
Chemical Substances | Propolis (9009-62-5) ; Anti-Bacterial Agents ; Ethanol (3K9958V90M) ; Anti-Inflammatory Agents |
Language | English |
Publishing date | 2023-07-23 |
Publishing country | Switzerland |
Document type | Journal Article |
ZDB-ID | 2019364-6 |
ISSN | 1422-0067 ; 1422-0067 ; 1661-6596 |
ISSN (online) | 1422-0067 |
ISSN | 1422-0067 ; 1661-6596 |
DOI | 10.3390/ijms241411831 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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