Article ; Online: Dual Antiplatelet Therapy with 3
Cardiovascular drugs and therapy
2022 Volume 37, Issue 4, Page(s) 695–703
Abstract: Purpose: This study aims to assess the association between body mass index (BMI) and platelet reactivity in STEMI patients treated with oral 3: Methods: Overall, 429 STEMI patients were enrolled in this study. Patients were divided into two groups ... ...
Abstract | Purpose: This study aims to assess the association between body mass index (BMI) and platelet reactivity in STEMI patients treated with oral 3 Methods: Overall, 429 STEMI patients were enrolled in this study. Patients were divided into two groups according to BMI (BMI < 25 vs ≥ 25 kg/m Results: After propensity score matching, patients with BMI ≥ 25 had similar values of baseline platelet reactivity, while they had higher level of platelet reactivity at 1 and 2 h after the LD and higher rate of HRPT. Furthermore, multivariate analysis demonstrated that BMI ≥ 25 was an independent predictor of HTPR at 2 h (OR 2.01, p = .009). Conversely, starting from 4 h after the LD, platelet reactivity values and HRPT rates were comparable among the two study groups. Conclusions: A BMI ≥ 25 kg/m |
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MeSH term(s) | Humans ; Platelet Aggregation Inhibitors ; Ticagrelor ; Prasugrel Hydrochloride/adverse effects ; Body Mass Index ; ST Elevation Myocardial Infarction/diagnosis ; ST Elevation Myocardial Infarction/drug therapy ; Blood Platelets ; Purinergic P2Y Receptor Antagonists/therapeutic use ; Percutaneous Coronary Intervention/adverse effects ; Treatment Outcome |
Chemical Substances | Platelet Aggregation Inhibitors ; Ticagrelor (GLH0314RVC) ; Prasugrel Hydrochloride (G89JQ59I13) ; Purinergic P2Y Receptor Antagonists |
Language | English |
Publishing date | 2022-02-17 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 639068-7 |
ISSN | 1573-7241 ; 0920-3206 |
ISSN (online) | 1573-7241 |
ISSN | 0920-3206 |
DOI | 10.1007/s10557-022-07322-2 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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