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  1. Article ; Online: Impact of junior doctor strikes on patient flow in the emergency department: a cross-sectional analysis.

    Ravioli, Svenja / Jina, Raeesa / Risk, Omar / Cantle, Fleur

    European journal of emergency medicine : official journal of the European Society for Emergency Medicine

    2023  Volume 31, Issue 1, Page(s) 53–58

    Abstract: Background and importance: Healthcare worker strikes are a global phenomenon. Mortality and morbidity seem to be unaffected by doctor strikes, but there is little evidence on the impact on emergency department (ED) flow and patient characteristics. In ... ...

    Abstract Background and importance: Healthcare worker strikes are a global phenomenon. Mortality and morbidity seem to be unaffected by doctor strikes, but there is little evidence on the impact on emergency department (ED) flow and patient characteristics. In March and April 2023, two consecutive UK junior doctor strikes occurred.
    Objectives: This study investigated the impact of junior doctor strikes on ED patient flow. Additionally, variation in patient presentations was compared between non-strike and strike days.
    Design, setting and participants: This cross-sectional study was conducted at King's College Hospital ED, a university hospital in London. All ED attendances during the 72- and 96-hour strike actions were compared with the corresponding non-strike days of the previous week.
    Outcome measures and analysis: National key performance indicators (KPIs) were analysed and compared between non-strike and strike days. Patients' demographics, acuity and diagnoses were compared. Outcome measures included number of 4-hour breaches, number of patients admitted or discharged and ED mortality. Staff seniority was categorised into levels for analysis.
    Main results: There was increased ED patient flow during strike days with a significantly shorter total time in department in March [240 min (IQR 155-469) vs. 286 min (IQR 198.5-523.5), P  < 0.001] and in April [222.5 min (IQR 147-351) vs. 251.5 min (IQR 174-443), P  < 0.001]. Time to first clinician, treatment, and decision to admit were all shorter during both strike actions. Number of attendances, acuity, diagnoses, admission, discharge, and mortality rates were similar during strike and non-strike days. Staffing numbers were lower or equivalent on strike days but level of seniority was higher ( P  < 0.001).
    Conclusion: The improved KPIs and increased patient flow during strike days, while multifactorial, seem largely attributed to the higher number of senior staff. Patient presentations and outcomes were unaffected by junior doctor strike action.
    MeSH term(s) Humans ; Cross-Sectional Studies ; Emergency Service, Hospital ; Medical Staff, Hospital ; Hospitalization ; Patient Discharge
    Language English
    Publishing date 2023-10-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1233544-7
    ISSN 1473-5695 ; 0969-9546
    ISSN (online) 1473-5695
    ISSN 0969-9546
    DOI 10.1097/MEJ.0000000000001093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Clinical features associated with ADB-BUTINACA exposure in patients attending emergency departments in England.

    King, A / Hill, S L / Pucci, M / Bailey, G / Keating, L / Macfarlane, R / Cantle, F / Hudson, S / Thomas, S H L

    Clinical toxicology (Philadelphia, Pa.)

    2022  Volume 60, Issue 10, Page(s) 1094–1098

    Abstract: Objective: Synthetic cannabinoid receptor agonists (SCRA) are commonly encountered new psychoactive substances. Here we report the recent detection of ADB-BUTINACA in samples from patients attending United Kingdom emergency departments with toxicity ... ...

    Abstract Objective: Synthetic cannabinoid receptor agonists (SCRA) are commonly encountered new psychoactive substances. Here we report the recent detection of ADB-BUTINACA in samples from patients attending United Kingdom emergency departments with toxicity after suspected drug misuse and describe the associated clinical features.
    Methods: Consenting adults (≥16 y) presenting to participating hospitals with toxicity after suspected drug misuse have been included in the Identification Of Novel psychoActive substances (IONA) study since March 2015. Demographic and clinical features are recorded and blood and/or urine samples analysed using high-resolution accurate mass liquid chromatography-mass spectrometry.
    Results: By December 2021, analytical data were available for 1279 IONA participants and ADB-BUTINACA was detected in at least one sample from 10 (9 males, age range 16-51 median 45 years), all presenting since February 2021. Smoking 'spice' was reported by four patients, two had ingested edible "cannabis" gums and four reported heroin use (2 intravenous, 1 smoked, 1 route not known). Co-use of pregabalin (oral) and crack cocaine (smoked) were also reported. In 3 cases ADB-BUTINACA was the only substance detected, while in seven other substances of misuse were also detected including other SCRA, opioids, benzodiazepines cocaine and pregabalin. Clinical features reported in these 2 groups respectively included reduced level of consciousness (3/3, 6/7), agitation (0/3, 4/7), tachycardia (0/3, 3/7), seizures (1/3, 1/7), hallucinations (1/3, 1/7), hypotension (1/3, 1/7). Metabolic acidosis (1/3, 0/7) and respiratory acidosis (1/3, 0/7), All 10 patients recovered with supportive care, including intubation and ventilation for one case. The median length of hospital stay was 19 h (range 2.6-131 h).
    Conclusions: ADB-BUTINACA has recently emerged as a drug of misuse in England. Clinical features of toxicity are consistent with those of other SCRA and include reduced level of consciousness, respiratory and/or metabolic acidosis, seizures, confusion and hallucinations.
    MeSH term(s) Adult ; Male ; Humans ; Adolescent ; Young Adult ; Middle Aged ; Cannabinoid Receptor Agonists ; Crack Cocaine ; Heroin ; Pregabalin ; Emergency Service, Hospital ; England/epidemiology ; Hallucinations ; Benzodiazepines ; Seizures
    Chemical Substances Cannabinoid Receptor Agonists ; Crack Cocaine ; Heroin (70D95007SX) ; Pregabalin (55JG375S6M) ; Benzodiazepines (12794-10-4)
    Language English
    Publishing date 2022-08-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 204476-6
    ISSN 1556-9519 ; 0009-9309 ; 0731-3810 ; 1556-3650
    ISSN (online) 1556-9519
    ISSN 0009-9309 ; 0731-3810 ; 1556-3650
    DOI 10.1080/15563650.2022.2101469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comparison of presentations to the emergency department during the COVID-19 pandemic (COPED-C).

    Kociejowski, A / Hobart, C / Jina, R / Aberman, I / Backhurst, E / Beaumont, A / Crompton, J / Sneep, R / Cantle, F / Dodhia, H

    Journal of public health (Oxford, England)

    2021  Volume 43, Issue 4, Page(s) 731–738

    Abstract: Background: Concerns have been raised that patients requiring emergency care may not have accessed healthcare services during coronavirus disease 2019 (COVID-19) lockdown.: Methods: This case control study aimed to understand changes in ... ...

    Abstract Background: Concerns have been raised that patients requiring emergency care may not have accessed healthcare services during coronavirus disease 2019 (COVID-19) lockdown.
    Methods: This case control study aimed to understand changes in characteristics and diagnosis of patients attending a large UK Emergency Department (ED) during the first wave of the COVID-19 pandemic (March-May 2020) compared with equivalent weeks in 2019.
    Results: We found a 50.7% drop in first attendances to the ED in 2020. Likelihood of attendance and admission decreased for paediatric patients and increased for patients ≥ 46 years, and for men. Likelihood of admission increased for all Black ethnic groups and for patients from the most deprived index of multiple deprivation quintiles. This shift to an older, male, more deprived patient population with greater representation of ethnic minority groups was amplified in the 'Infections' diagnostic category.
    Conclusions: COVID-19 has dramatically impacted ED usage. Our analysis contributes to local resource planning and understanding of changes in healthcare-seeking behaviour during the pandemic. Future research to identify positive behaviour changes could help sustain a reduction in non-urgent visits in the longer term.
    MeSH term(s) COVID-19 ; Case-Control Studies ; Child ; Communicable Disease Control ; Emergency Service, Hospital ; Ethnic and Racial Minorities ; Ethnicity ; Humans ; Male ; Minority Groups ; Pandemics ; Retrospective Studies ; SARS-CoV-2
    Language English
    Publishing date 2021-03-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2142082-8
    ISSN 1741-3850 ; 1741-3842
    ISSN (online) 1741-3850
    ISSN 1741-3842
    DOI 10.1093/pubmed/fdab059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: High-Flow Humidified Oxygen as an Early Intervention in Children With Acute Severe Asthma: Protocol for a Feasibility Randomized Controlled Trial.

    Rojas-Anaya, Hector / Kapur, Akshat / Roberts, Graham / Roland, Damian / Gupta, Atul / Lazner, Michaela / Bayreuther, Jane / Pappachan, John / Jones, Christina / Bremner, Stephen / Cantle, Fleur / Seddon, Paul

    JMIR research protocols

    2024  Volume 13, Page(s) e54081

    Abstract: Background: Acute severe asthma (ASA) is a leading cause of hospital attendance in children. Standard first-line therapy consists of high-dose inhaled bronchodilators plus oral corticosteroids. Treatment for children who fail to respond to first-line ... ...

    Abstract Background: Acute severe asthma (ASA) is a leading cause of hospital attendance in children. Standard first-line therapy consists of high-dose inhaled bronchodilators plus oral corticosteroids. Treatment for children who fail to respond to first-line therapy is problematic: the use of intravenous agents is inconsistent, and side effects are frequent. High-flow humidified oxygen (HiFlo) is widely used in respiratory conditions and is increasingly being used in ASA, but with little evidence for its effectiveness. A well-designed, adequately powered randomized controlled trial (RCT) of HiFlo therapy in ASA is urgently needed, and feasibility data are required to plan such an RCT. In this study, we describe the protocol for a feasibility study designed to fill this knowledge gap.
    Objective: This study aims to establish whether a full RCT of early HiFlo therapy in children with ASA can be conducted successfully and safely, to establish whether recruitment using deferred consent is practicable, and to define appropriate outcome measures and sample sizes for a definitive RCT. The underlying hypothesis is that early HiFlo therapy in ASA will reduce the need for more invasive treatments, allow faster recovery and discharge from hospital, and in both these ways reduce distress to children and their families.
    Methods: We conducted a feasibility RCT with deferred consent to assess the use of early HiFlo therapy in children aged 2 to 11 years with acute severe wheeze not responding to burst therapy (ie, high-dose inhaled salbutamol with or without ipratropium). Children with a Preschool Respiratory Assessment Measure score ≥5 after burst therapy were randomized to commence HiFlo therapy or follow standard care. The candidate primary outcomes assessed were treatment failure requiring escalation and time to meet hospital discharge criteria. Patient and parent experiences were also assessed using questionnaires and telephone interviews.
    Results: The trial was opened to recruitment in February 2020 but was paused for 15 months owing to the COVID-19 pandemic. The trial was reopened at the lead site in July 2021 and opened at the other 3 sites from August to December 2022. Recruitment was completed in June 2023.
    Conclusions: This feasibility RCT of early HiFlo therapy in children with ASA recruited to the target despite major disturbances owing to the COVID-19 pandemic. The data are currently being analyzed and will be published separately.
    Trial registration: International Standard Randomised Controlled Trial Number Registry ISRCTN78297040; https://www.isrctn.com/ISRCTN78297040.
    International registered report identifier (irrid): DERR1-10.2196/54081.
    Language English
    Publishing date 2024-03-28
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2719222-2
    ISSN 1929-0748
    ISSN 1929-0748
    DOI 10.2196/54081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: What is a 'learning organization' in general practice? A case study.

    Cantle, F

    Health services management research

    2000  Volume 13, Issue 3, Page(s) 152–155

    Abstract: The focus of the research herein was to examine the main characteristics of a learning organization in a general practice. An ethnographic approach was taken. Blockage instrument, structured interviews and documentary evidence were used to establish the ... ...

    Abstract The focus of the research herein was to examine the main characteristics of a learning organization in a general practice. An ethnographic approach was taken. Blockage instrument, structured interviews and documentary evidence were used to establish the validity and the reliability of the research. Data were collected and analysed systematically. It is shown that the case study practice contains the characteristics of a learning organization and key management and organizational issues, such as policy making, practice management and performance management, are identified. Management strategies are offered and recommendations made both for the case study practice and generally for primary and secondary healthcare services. We hope that our research will guide further strategic planning in the case study practice, and that it will help other general practices and the NHS as a whole in the development of a learning organization.
    MeSH term(s) England ; Family Practice/organization & administration ; Health Services Research ; Humans ; Learning ; Organizational Case Studies ; Organizational Culture ; Organizational Innovation ; Staff Development ; State Medicine/organization & administration
    Language English
    Publishing date 2000-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 645114-7
    ISSN 0951-4848
    ISSN 0951-4848
    DOI 10.1177/095148480001300302
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The impact of the COVID-19 pandemic on the number of presentations of penetrating injuries to a UK major trauma centre.

    Hickland, Maria M / Massouh, Philippa / Sutthakorn, Roxanne E / Greenslade, Charlotte / Jennings, Cara / Cantle, Fleur / Bew, Duncan

    Journal of public health (Oxford, England)

    2021  Volume 44, Issue 1, Page(s) e126–e132

    Abstract: Background: Knife-related violence is of growing concern in the UK. This study aims to investigate the impact of the COVID-19 pandemic on the frequency of penetrating injuries at a UK major trauma centre.: Methods: This was a retrospective study ... ...

    Abstract Background: Knife-related violence is of growing concern in the UK. This study aims to investigate the impact of the COVID-19 pandemic on the frequency of penetrating injuries at a UK major trauma centre.
    Methods: This was a retrospective study comparing the number of patients attending the emergency department of King's College Hospital (KCH) with a penetrating injury (gunshot or stab wound) during the 'pandemic year' (1 March 2020-28 February 2021) compared with the equivalent time period in the previous year. Penetrating injuries as a result of self-harm were excluded. The primary outcome was to assess whether there were any changes to the frequency of presentations during three periods of national lockdowns.
    Results: Lockdown 1 showed a 48.45% reduction in presentations in the 'pandemic year' compared to the previous year, lockdown 2 showed a 31.25% reduction; however, lockdown 3 showed an 8.89% increase in the number of presentations.
    Conclusion: Our findings suggest that despite the initial reduction in the number of presentations of penetrating injury during lockdown 1, this returned to normal levels by lockdown 3. Further research is required to understand the effects of government-imposed restrictions on interpersonal violence and identify appropriate methods of outreach prevention during a pandemic.
    MeSH term(s) COVID-19/epidemiology ; Communicable Disease Control ; Humans ; Pandemics ; Retrospective Studies ; SARS-CoV-2 ; Trauma Centers ; United Kingdom/epidemiology
    Language English
    Publishing date 2021-10-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2142082-8
    ISSN 1741-3850 ; 1741-3842
    ISSN (online) 1741-3850
    ISSN 1741-3842
    DOI 10.1093/pubmed/fdab333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Intravenous access in children in the emergency department.

    Sturgeon, Jonathan / Lifford, Rhiannon / Cantle, Fleur

    Pediatric emergency care

    2014  Volume 30, Issue 3, Page(s) 226

    MeSH term(s) Catheterization, Peripheral ; Child ; Emergency Service, Hospital ; Emergency Treatment ; Humans ; Infusions, Intraosseous
    Language English
    Publishing date 2014-03
    Publishing country United States
    Document type Letter
    ZDB-ID 632588-9
    ISSN 1535-1815 ; 0749-5161
    ISSN (online) 1535-1815
    ISSN 0749-5161
    DOI 10.1097/PEC.0000000000000096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Education. The nurse therapist.

    Cantle, F

    Nursing mirror

    1985  Volume 161, Issue 2, Page(s) 46–48

    MeSH term(s) Adult ; Behavior Therapy/education ; Female ; Humans ; Phobic Disorders/therapy ; Psychiatric Nursing/education
    Language English
    Publishing date 1985-07-10
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 603412-3
    ISSN 0029-6511
    ISSN 0029-6511
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Implementing treat-to-target urate-lowering therapy during hospitalisations for gout flares.

    Russell, Mark D / Ameyaw-Kyeremeh, Louise / Dell'Accio, Flora / Lapham, Heather / Head, Natalie / Stovin, Christopher / Patel, Vishit / Clarke, Benjamin D / Nagra, Deepak / Alveyn, Edward / Adas, Maryam A / Bechman, Katie / de la Puente, María A / Ellis, Benjamin / Byrne, Corrine / Patel, Rina / Rutherford, Andrew I / Cantle, Fleur / Norton, Sam /
    Roddy, Edward / Hudson, Joanna / Cope, Andrew P / Galloway, James B

    Rheumatology (Oxford, England)

    2023  

    Abstract: Objectives: To evaluate a strategy designed to optimise care and increase uptake of urate-lowering therapy (ULT) during hospitalisations for gout flares.: Methods: We conducted a prospective cohort study to evaluate a strategy that combined optimal ... ...

    Abstract Objectives: To evaluate a strategy designed to optimise care and increase uptake of urate-lowering therapy (ULT) during hospitalisations for gout flares.
    Methods: We conducted a prospective cohort study to evaluate a strategy that combined optimal in-hospital gout management with a nurse-led, follow-up appointment, followed by handover to primary care. Outcomes, including ULT initiation, urate target attainment, and re-hospitalisation rates, were compared between patients hospitalised for flares in the 12 months post-implementation and a retrospective cohort of hospitalised patients from 12 months pre-implementation.
    Results: 119 and 108 patients, respectively, were hospitalised for gout flares in the 12 months pre- and post-implementation. For patients with 6-month follow-up data available (n = 94 and n = 97, respectively), the proportion newly initiated on ULT increased from 49.2% pre-implementation to 92.3% post-implementation (age/sex-adjusted odds ratio (aOR) 11.5; 95% confidence interval (CI) 4.36-30.5; p < 0.001). After implementation, more patients achieved a serum urate ≤360 micromol/L within 6 months of discharge (10.6% pre-implementation vs. 26.8% post-implementation; aOR 3.04; 95% CI 1.36-6.78; p = 0.007). The proportion of patients re-hospitalised for flares was 14.9% pre-implementation vs. 9.3% post-implementation (aOR 0.53, 95% CI 0.22 to 1.32; p = 0.18).
    Conclusion: Over 90% of patients were initiated on ULT after implementing a strategy to optimise hospital gout care. Despite increased initiation of ULT during flares, recurrent hospitalisations were not more frequent following implementation. Significant relative improvements in urate target attainment were observed post-implementation; however, for the majority of hospitalised gout patients to achieve urate targets, closer primary-secondary care integration is still needed.
    Language English
    Publishing date 2023-10-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/kead574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Early Epidemiological and Clinical Analysis of the First 200 Patients with COVID-19 Admitted via the Emergency Department in Kings College Hospital, London

    Sneep, Ruth / Cantle, Fleur / Brookes, Andrew / Jina, Raeesa / Williams, Sarah / Galloway, James / Norton, Sam / Udukala, Mangalanath / Birring, Surinder / Zuckerman, Mark

    SSRN Electronic Journal ; ISSN 1556-5068

    A Retrospective Cohort Study

    2020  

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.2139/ssrn.3576791
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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