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  1. Article: [Spindle-shaped diffuse large B-cell lymphoma of ovary: report of a case].

    Cao, H L / Wang, Z

    Zhonghua bing li xue za zhi = Chinese journal of pathology

    2017  Volume 46, Issue 12, Page(s) 859–860

    Language Chinese
    Publishing date 2017-12-28
    Publishing country China
    Document type Journal Article
    ZDB-ID 784533-9
    ISSN 0529-5807
    ISSN 0529-5807
    DOI 10.3760/cma.j.issn.0529-5807.2017.12.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2958: Show issues Location:
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  2. Article: [Advances of biological agents in the treatment of gastrointestinal acute graft-versus-host disease].

    Wu, J Y / Liu, X / Wang, S N / Jiang, E L / Wang, B M / Cao, H L

    Zhonghua nei ke za zhi

    2023  Volume 63, Issue 1, Page(s) 107–112

    Language Chinese
    Publishing date 2023-12-28
    Publishing country China
    Document type Journal Article
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    DOI 10.3760/cma.j.cn112138-20231004-00179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Single hydrogen-methane breath test for the diagnosis of small intestinal bacterial growth].

    Huang, H / Li, H Z / Wang, Y R / Song, Y / Wang, B M / Cao, H L / Jiang, K

    Zhonghua nei ke za zhi

    2023  Volume 62, Issue 11, Page(s) 1335–1340

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Methane/analysis ; Cross-Sectional Studies ; Intestine, Small/microbiology ; Bacteria ; Gastrointestinal Diseases ; Breath Tests/methods ; Hydrogen/analysis
    Chemical Substances Methane (OP0UW79H66) ; Hydrogen (7YNJ3PO35Z)
    Language Chinese
    Publishing date 2023-11-07
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    DOI 10.3760/cma.j.cn112138-20221111-00843
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Values of long noncoding RNA SAMMSON in the clinicopathologic features and the prognostic implications of human gastric cancer.

    Sun, S-B / Lin, S-X / Cao, H-L / Xiao, Z-Q

    European review for medical and pharmacological sciences

    2020  Volume 24, Issue 11, Page(s) 6080–6087

    Abstract: Objective: The aim of this study was to explore the clinical significance of lncRNA-survival associated mitochondrial melanoma-specific oncogenic non-coding RNA (lncRNA-SAMMSON) in the development and clinicopathological parameters of gastric cancer (GC) ...

    Abstract Objective: The aim of this study was to explore the clinical significance of lncRNA-survival associated mitochondrial melanoma-specific oncogenic non-coding RNA (lncRNA-SAMMSON) in the development and clinicopathological parameters of gastric cancer (GC).
    Patients and methods: Tissue specimens were collected from GC patients who received treatment in our hospital. Real-time quantitative polymerase chain reaction (QRT-PCR) was used to determine lncRNA-SAMMSON expression. Small interfering RNA (siRNA) was transfected to suppress the expression of lncRNA-SAMMSON in vitro. Pearson's χ2-test  was used to investigate the interaction of lncRNA-SAMMSON with clinicopathological parameters of GC patients. Kaplan-Meier method and Log rank analysis were used to analyze the progression-free survival time and overall time of GC patients. Furthermore, transwell assay and wound healing assay were conducted to determine the invasion and migration abilities of GC cells, respectively.
    Results: QRT-PCR results showed that lncRNA-SAMMSON was abnormally overexpressed in GC tissues and cells (p<0.05). Pearson's χ2-test illustrated that clinical stage, distant metastasis and lymph node metastasis were closely related to lncRNA-SAMMSON expression in GC patients (p<0.05). Kaplan-Meier survival analysis represented that GC patients with high lncRNA-SAMMSON expression had significantly shorter progression-free survival time and overall survival time (p<0.05). Transwell assay and wound healing assay proved that inhibition of lncRNA-SAMMSON in GC cells dramatically reduced the invasion and migration abilities of GC cells, respectively (p<0.05).
    Conclusions: LncRNA-SAMMSON played an important role in the development of GC, which might be regarded as a new target for the diagnosis and treatment of GC.
    MeSH term(s) Cell Movement ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Stomach Neoplasms/diagnosis ; Stomach Neoplasms/genetics ; Stomach Neoplasms/metabolism ; Tumor Cells, Cultured
    Chemical Substances RNA, Long Noncoding
    Language English
    Publishing date 2020-06-22
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202006_21503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1887: Show issues Location:
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  5. Article ; Online: The research on medical image classification algorithm based on PLSA-BOW model.

    Cao, C H / Cao, H L

    Technology and health care : official journal of the European Society for Engineering and Medicine

    2016  Volume 24 Suppl 2, Page(s) S665–74

    Abstract: Background: With the rapid development of modern medical imaging technology, medical image classification has become more important for medical diagnosis and treatment.: Objective: To solve the existence of polysemous words and synonyms problem, this ...

    Abstract Background: With the rapid development of modern medical imaging technology, medical image classification has become more important for medical diagnosis and treatment.
    Objective: To solve the existence of polysemous words and synonyms problem, this study combines the word bag model with PLSA (Probabilistic Latent Semantic Analysis) and proposes the PLSA-BOW (Probabilistic Latent Semantic Analysis-Bag of Words) model.
    Methods: In this paper we introduce the bag of words model in text field to image field, and build the model of visual bag of words model.
    Results: The method enables the word bag model-based classification method to be further improved in accuracy.
    Conclusions: The experimental results show that the PLSA-BOW model for medical image classification can lead to a more accurate classification.
    MeSH term(s) Algorithms ; Diagnostic Imaging/classification ; Humans ; Models, Theoretical ; Research ; Semantics
    Language English
    Publishing date 2016-04-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1159961-3
    ISSN 1878-7401 ; 0928-7329
    ISSN (online) 1878-7401
    ISSN 0928-7329
    DOI 10.3233/THC-161194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Research progress of obstructive sleep apnea syndrome on colorectal cancer].

    Gao, J / Cao, H L / Chen, C / Wang, B M / Zhang, Q

    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

    2021  Volume 44, Issue 11, Page(s) 1004–1008

    MeSH term(s) Colorectal Neoplasms ; Humans ; Sleep Apnea, Obstructive/complications
    Language Chinese
    Publishing date 2021-11-10
    Publishing country China
    Document type Journal Article
    ZDB-ID 1027965-9
    ISSN 1001-0939
    ISSN 1001-0939
    DOI 10.3760/cma.j.cn112147-20210305-00148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [New insight into the pathogenesis and treatment of juvenile polyposis syndrome].

    Zhang, H / Maimaitiaili, Maimaitiabudu / Liu, Y / Wang, X H / Wang, B M / Cao, H L

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2020  Volume 58, Issue 5, Page(s) 432–435

    MeSH term(s) Humans ; Intestinal Polyposis/congenital ; Intestinal Polyposis/pathology ; Intestinal Polyposis/therapy ; Neoplastic Syndromes, Hereditary/pathology ; Neoplastic Syndromes, Hereditary/therapy
    Language Chinese
    Publishing date 2020-05-12
    Publishing country China
    Document type Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.cn112140-20190827-00544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 3292: Show issues Location:
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  8. Article: [Analysis of project results of preventive medicine from the National Natural Science Foundation of China in 2017].

    Chen, S Y / Dai, Y F / Cao, H L / Qin, L Q / Zhang, Z W

    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

    2019  Volume 53, Issue 4, Page(s) 433–436

    Abstract: We analyzed the project results of preventive medicine from the National Natural Science Foundation of China (NSFC) finished in 2017 based on the project-ending reports and data on science fund sharing service network. A total of 406 projects in this ... ...

    Abstract We analyzed the project results of preventive medicine from the National Natural Science Foundation of China (NSFC) finished in 2017 based on the project-ending reports and data on science fund sharing service network. A total of 406 projects in this field were completed in 2017. A total of 3 122 published articles supported by these projects, including 1 789 articles in science citation index (SCI) journals and 525 articles in Chinese core journals. In addition, there were 224 patent application/software copyright and 589 trained postgraduates. The top three sub-disciplines of project were non-communicable disease epidemiology, human nutrition and hygienic toxicology, accounting for 45.32% of the total number of completed projects. There were 12 institutions which had more than 10 finished projects, accounting for 41.87%. During the recent 5 years, the number of SCI articles and patents/software copyrights per project showed a general uptrend. It should be noted that the number of articles in Chinese core journals and postgraduates decreased in recent two years. Our analyses demonstrated that the project results should be guided by the new era policy of science fund to promote sustainable development of scientific research.
    MeSH term(s) China ; Foundations ; Humans ; Natural Science Disciplines ; Preventive Medicine
    Language Chinese
    Publishing date 2019-04-13
    Publishing country China
    Document type Journal Article
    ZDB-ID 604575-3
    ISSN 0253-9624
    ISSN 0253-9624
    DOI 10.3760/cma.j.issn.0253-9624.2019.04.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: lncRNA-RMRP promotes proliferation, migration and invasion of bladder cancer via miR-206.

    Cao, H-L / Liu, Z-J / Huang, P-L / Yue, Y-L / Xi, J-N

    European review for medical and pharmacological sciences

    2019  Volume 23, Issue 3, Page(s) 1012–1021

    Abstract: Objective: The incidence of bladder cancer (BC) is common in the world, but its detail mechanisms for occurrence and development remain unclear. Recently, long non-coding RNAs (lncRNAs) have been observed to play an important role in many different ... ...

    Abstract Objective: The incidence of bladder cancer (BC) is common in the world, but its detail mechanisms for occurrence and development remain unclear. Recently, long non-coding RNAs (lncRNAs) have been observed to play an important role in many different diseases. In this research, we mainly explored the role of the RNA component of mitochondrial RNA processing endoribonuclease (lncRNA-RMRP) in bladder cancer.
    Materials and methods: We used qRT-PCR to detect the expression of lncRNA-RMRP in bladder cancer patients and tumor cells, and the clinical significance was also analyzed. The methyl thiazolyl tetrazolium (MTT) assay was used to detect the cell proliferation, and we used transwell to detect the migration and invasion, after the lncRNA RMRP was inhibited. Western-blot was used to measure the relative protein expression level in bladder cancer cells after transfection with siRNA-NC or siRNA-RMRP.
    Results: We found that the lncRNA RMRP was highly expressed in bladder cancer tissue, compared with adjacent tissue. We also found that the expression of RMRP was closely related with the size, lymph node metastasis and survival time of patients. What's more, RMRP could promote the proliferation, migration and invasion of BC cell lines via regulating miR-206 as a sponge.
    Conclusions: According to the results, we found that lncRNA RMRP was closely related to the progression of bladder cancer, which could be a potential target for treating BC patients.
    MeSH term(s) Cell Line, Tumor ; Cell Movement/physiology ; Cell Proliferation/physiology ; Gene Expression Regulation, Neoplastic/physiology ; Humans ; MicroRNAs/biosynthesis ; MicroRNAs/metabolism ; Neoplasm Invasiveness/physiopathology ; RNA, Long Noncoding/antagonists & inhibitors ; RNA, Long Noncoding/biosynthesis ; RNA, Long Noncoding/metabolism ; RNA, Long Noncoding/physiology ; RNA, Small Interfering/physiology ; RNA-Binding Motifs ; Transfection ; Urinary Bladder Neoplasms/metabolism ; Urinary Bladder Neoplasms/physiopathology
    Chemical Substances MIRN206 microRNA, human ; MicroRNAs ; RMRP non-coding RNA, human ; RNA, Long Noncoding ; RNA, Small Interfering
    Language English
    Publishing date 2019-02-15
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_201902_16988
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Moth-eaten essential syphilitic alopecia.

    Cao, H-L / Engle, M Y / Shen, Y-F / Wang, J-Y

    QJM : monthly journal of the Association of Physicians

    2015  Volume 108, Issue 2, Page(s) 157–158

    MeSH term(s) Adult ; Alopecia/etiology ; Anti-Bacterial Agents/administration & dosage ; Humans ; Male ; Penicillin G Benzathine/administration & dosage ; Syphilis/diagnosis ; Syphilis/drug therapy ; Syphilis Serodiagnosis/methods
    Chemical Substances Anti-Bacterial Agents ; Penicillin G Benzathine (RIT82F58GK)
    Language English
    Publishing date 2015-02
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcu147
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