Article ; Online: From gut to brain: understanding the role of microbiota in inflammatory bowel disease.
2024 Volume 15, Page(s) 1384270
Abstract: With the proposal of the "biological-psychological-social" model, clinical decision-makers and researchers have paid more attention to the bidirectional interactive effects between psychological factors and diseases. The brain-gut-microbiota axis, as an ... ...
Abstract | With the proposal of the "biological-psychological-social" model, clinical decision-makers and researchers have paid more attention to the bidirectional interactive effects between psychological factors and diseases. The brain-gut-microbiota axis, as an important pathway for communication between the brain and the gut, plays an important role in the occurrence and development of inflammatory bowel disease. This article reviews the mechanism by which psychological disorders mediate inflammatory bowel disease by affecting the brain-gut-microbiota axis. Research progress on inflammatory bowel disease causing "comorbidities of mind and body" through the microbiota-gut-brain axis is also described. In addition, to meet the needs of individualized treatment, this article describes some nontraditional and easily overlooked treatment strategies that have led to new ideas for "psychosomatic treatment". |
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MeSH term(s) | Humans ; Gastrointestinal Microbiome ; Brain/metabolism ; Inflammatory Bowel Diseases/etiology ; Inflammatory Bowel Diseases/therapy ; Inflammatory Bowel Diseases/metabolism ; Microbiota ; Mental Disorders/metabolism |
Language | English |
Publishing date | 2024-03-21 |
Publishing country | Switzerland |
Document type | Journal Article ; Review ; Research Support, Non-U.S. Gov't |
ZDB-ID | 2606827-8 |
ISSN | 1664-3224 ; 1664-3224 |
ISSN (online) | 1664-3224 |
ISSN | 1664-3224 |
DOI | 10.3389/fimmu.2024.1384270 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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