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Article ; Online: Retraction RETRACTION of "Methylation of the RASSFIA promoter in breast cancer" by Y. Ji, H.H. Jin, M.D. Wang, W.X. Cao, J.L. Bao - Genet. Mol. Res. 15 (2): gmr.15028261 (2016) - DOI: 10.4238/gmr.15028261.

Ji, Y / Jin, H H / Wang, M D / Cao, W X / Bao, J L

2016 Volume 15, Issue 4

Abstract: The retracted article is: Ji Y, Jin HH, Wang MD, Cao WX, et al. (2016). Methylation of the RASSFIA promoter in breast cancer. Genet. Mol. Res. 15: gmr.15028261. There are significant parts of this article (particularly, in the discussion section) that ... ...

Abstract	The retracted article is: Ji Y, Jin HH, Wang MD, Cao WX, et al. (2016). Methylation of the RASSFIA promoter in breast cancer. Genet. Mol. Res. 15: gmr.15028261. There are significant parts of this article (particularly, in the discussion section) that are copied from "Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome", by Jia Xu, Priya B Shetty, Weiwei Feng, Carol Chenault, Robert C Bast Jr, Jean-Pierre J Issa, Susan G Hilsenbeck and Yinhua Yu, published in BMC Cancer 2012; 12: 243. DOI: 10.1186/1471-2407-12-243. The first paragraphs of both discussions are identical. This is concerning. The abstract and introduction sections have much of their text plagiarized. Overall, there is high plagiarism detected. The GMR editorial staff was alerted and after a thorough investigation, we have strong reason to believe that the peer review process was failure and, after review and contacting the authors, the editors of Genetics and Molecular Research decided to retract the article in accordance with the recommendations of the Committee on Publication Ethics (COPE). The authors and their institutions were advised of this serious breach of ethics.
Language	English
Publishing date	2016-10-07
Publishing country	Brazil
Document type	Journal Article ; Retraction of Publication
ZDB-ID	2114039-X
ISSN	1676-5680 ; 1676-5680
ISSN (online)	1676-5680
ISSN	1676-5680
DOI	10.4238/gmr.150482611
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Methylation of the RASSFIA promoter in breast cancer.

Ji, Y / Jin, H H / Wang, M D / Cao, W X / Bao, J L

publication RETRACTED

Genetics and molecular research : GMR

2016 Volume 15, Issue 2

Abstract: Tumor suppressor genes are the key targets of hypermethylation in breast cancer and may therefore lead to malignancy by deregulation of cell growth and division. Our previous pilot study with pairs of malignant and normal breast tissues identified a ... ...

Abstract	Tumor suppressor genes are the key targets of hypermethylation in breast cancer and may therefore lead to malignancy by deregulation of cell growth and division. Our previous pilot study with pairs of malignant and normal breast tissues identified a correlation between RASSFIA gene methylation and breast cancer. To determine the relationship between RASSFIA methylation and breast cancer, we conducted a larger study. We took samples from 108 patients with breast cancer, 28 patients with benign breast tumors, and 33 subjects with normal breast tissues at the Second Affiliated Hospital of Nanjing Medical University at Wuxi between July 2013 and September 2015. We used the samples to investigate methylation levels of the RASSF1A gene for associations with breast cancer. Quantitative real-time polymerase chain reaction (PCR) and methylation-specific PCR were used to investigate the levels of RASSF1A mRNA expression and RASSF1A methylation, respectively. RASSFIA was not expressed in 22 of the 108 breast cancer tissue samples (20.37%), and there was no statistically significant difference (P > 0.05); however, RASSFIA expression was significantly lower than that in the normal breast tissue samples (P < 0.05). Moreover, the methylation rate of the RASSFIA gene promoter was significantly higher in the breast cancer tissues (64.81%) than in the normal breast tissues (18.18%) and benign breast tumors (17.86%) (P < 0.05). High methylation of the RASSF1A gene promoter was an important reason for its downregulation, and the gene played a critical regulated role in the incidence and development of breast cancer.
Language	English
Publishing date	2016-07-14
Publishing country	Brazil
Document type	Journal Article ; Retracted Publication
ZDB-ID	2114039-X
ISSN	1676-5680 ; 1676-5680
ISSN (online)	1676-5680
ISSN	1676-5680
DOI	10.4238/gmr.15028261
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Improving the estimation and partitioning of plant nitrogen in the RiceGrow model

Tang, L / Chang, R. J / Basso, B / Li, T / Zhen, F. X / Liu, L. L / Cao, W. X / Zhu, Y

Journal of agricultural science. 2018 Oct., v. 156, no. 8

2018

Abstract: Plant nitrogen (N) links with many physiological progresses of crop growth and yield formation. Accurate simulation is key to predict crop growth and yield correctly. The aim of the current study was to improve the estimation of N uptake and ... ...

Abstract	Plant nitrogen (N) links with many physiological progresses of crop growth and yield formation. Accurate simulation is key to predict crop growth and yield correctly. The aim of the current study was to improve the estimation of N uptake and translocation processes in the whole rice plant as well as within plant organs in the RiceGrow model by using plant and organ maximum, critical and minimum N dilution curves. The maximum and critical N (Nc) demand (obtained from the maximum and critical curves) of shoot and root and Nc demand of organs (leaf, stem and panicle) are calculated by N concentration and biomass. Nitrogen distribution among organs is computed differently pre- and post-anthesis. Pre-anthesis distribution is determined by maximum N demand with no priority among organs. In post-anthesis distribution, panicle demands are met first and then the remaining N is allocated to other organs without priority. The amount of plant N uptake depends on plant N demand and N supplied by the soil. Calibration and validation of the established model were performed on field experiments conducted in China and the Philippines with varied N rates and N split applications; results showed that this improved model can simulate the processes of N uptake and translocation well.
Keywords	Philippines ; agricultural sciences ; biomass ; leaves ; models ; nitrogen ; nitrogen content ; panicles ; plant nitrogen content ; rice ; soil ; China
Language	English
Dates of publication	2018-10
Size	p. 959-970.
Publishing place	Cambridge University Press
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	1498349-7
ISSN	1469-5146 ; 0021-8596
ISSN (online)	1469-5146
ISSN	0021-8596
DOI	10.1017/S0021859618001004
Database	NAL-Catalogue (AGRICOLA)

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Article: Reproductive biology of Chinese minnow Hemiculterella sauvagei Warpachowski, 1888 in the Chishui River, China

Wang, J / Liu, F / Zhang, X / Cao, W.‐X / Liu, H.‐Z / Gao, X

Journal of applied ichthyology. 2014 Apr., v. 30, no. 2

2014

Abstract: This study describes the reproductive biology of the Chinese minnow Hemiculterella sauvagei. The length‐weight relationship, sex ratio, spawning season, size at first maturity, and fecundity were analyzed based on 685 specimens collected from the Chishui ...

Abstract	This study describes the reproductive biology of the Chinese minnow Hemiculterella sauvagei. The length‐weight relationship, sex ratio, spawning season, size at first maturity, and fecundity were analyzed based on 685 specimens collected from the Chishui River between July 2011 and July 2012. The relationship between standard length (SL) and body weight (BW) were estimated as BW� =� 2.14� ×� 10⁻⁴� ×� SL².⁸⁰¹ (R²� =� 0.839; N� =� 413; P� <� 0.05) for females and BW� =� 1.31 ×� 10⁻⁴� ×� SL³.⁰⁰¹ (R²� =� 0.868; N� =� 272; P� <� 0.05) for males. The female to male sex ratio, 1.52� :� 1, differed significantly from a 1� :� 1 ratio. Females predominated in standard lengths >12� cm. Analyses of the monthly variation in the gonadosomatic index (GSI), the monthly proportions of macroscopic gonadal maturity, and the size distribution of oocytes consistently suggested a prolonged spawning season of H.� sauvagei from March to August, with a peak from April to May. Logistic curves describing the relationship between proportion of maturity (Pᵣ) at each length interval and standard length were estimated as Pᵣ� =� 1/(1� +� e²⁶.⁸⁶⁷–⁰.³⁰⁶ Sᴸ) (R²� =� 0.999; N� =� 413; P� <� 0.05) for females and Pᵣ� =� 1/(1� +� e¹⁰.⁵²²–⁰.¹⁴² Sᴸ) (R²� =� 0.999; N� =� 272; P� <� 0.05) for males. Size at first maturity was estimated as 7.4� cm for males and 8.8� cm SL for females. Absolute fecundity varied from 563 to 5052, with a mean of 2413� ±� 874 oocytes per ovary. The relative fecundity was estimated to be 41–299, with a mean of 171� ±� 55 oocytes per ovary. The present study provides useful information for fishery management and resources conservation.
Keywords	body weight ; fecundity ; females ; fisheries management ; gonadosomatic index ; males ; minnows ; oocytes ; rivers ; sex ratio ; spawning ; China
Language	English
Dates of publication	2014-04
Size	p. 314-321.
Publishing place	Blackwell Wissenschafts-Verlag
Document type	Article
ZDB-ID	283875-8
ISSN	0175-8659
ISSN	0175-8659
DOI	10.1111/jai.12353
Database	NAL-Catalogue (AGRICOLA)

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Z 4247: Show issues

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Article ; Online: SPE-UPLC-MS/MS for the determination of phthalate monoesters in rats urine and its application to study the effects of food emulsifier on the bioavailability of priority controlling PAEs.

Xu, R / Gao, H T / Zhu, F / Cao, W X / Yan, Y H M / Zhou, X / Xu, Q / Ji, W L

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2016 Volume 1012-1013, Page(s) 97–105

Abstract: This research was mainly focused on the effects of food emulsifier on the bioavailability of six priority controlling phthalate acid esters (PAEs) for the further accurate assessment of their toxic effects, using the corresponding phthalate acid ... ...

Abstract	This research was mainly focused on the effects of food emulsifier on the bioavailability of six priority controlling phthalate acid esters (PAEs) for the further accurate assessment of their toxic effects, using the corresponding phthalate acid monoesters (PAMEs) in rats urine as biomarkers. Glycerin monostearate was chosen as typical food emulsifier. A method was established to determine PAMEs in urine from rats either in experimental group (integrated gavaged with glycerin monostearate and PAEs) or in control group (gavaged with PAEs only), by using solid-phase extraction (SPE) coupled with ultra performance liquid chromatography tandem mass spectrometry (SPE-UPLC-MS/MS). Extraction recoveries were more than 75% for all the PAMEs; the calibration curve was linear in the range of 1.0-1000.0ng/mL with R(2)>0.995; the limits of detection (LOD) were 0.30ng/mL-0.50ng/mL. In addition, by analysing quality control (QC) urine samples in 3 days, it showed that the method was precise and accurate, for the intra-day and inter-day RSD within 16%, and the accuracy more than 82%. Internal exposure amount of all PAEs in experimental group was significantly higher than that in control group with p values of less than 0.05 except for butyl benzyl phthalates (BBP) (P=0.07). The bioavailability of all PAEs ranged from 5.03% to 109.35% with the presence of food emulsifiers glycerin monostearate, observably higher than that without glycerin monostearate (1.12% to 54.39%). It indicated that food emulsifiers increased the bioavailability of PAEs and may lead to potential food safety risk, which should bring awareness and be further studied.
MeSH term(s)	Animals ; Biological Availability ; Chromatography, High Pressure Liquid/methods ; Emulsifying Agents/chemistry ; Emulsifying Agents/metabolism ; Limit of Detection ; Linear Models ; Male ; Phthalic Acids/isolation & purification ; Phthalic Acids/metabolism ; Phthalic Acids/pharmacokinetics ; Phthalic Acids/urine ; Rats ; Rats, Sprague-Dawley ; Reproducibility of Results ; Solid Phase Extraction/methods ; Tandem Mass Spectrometry/methods
Chemical Substances	Emulsifying Agents ; Phthalic Acids
Language	English
Publishing date	2016-02-15
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1180823-8
ISSN	1873-376X ; 0378-4347 ; 1570-0232 ; 1387-2273
ISSN (online)	1873-376X
ISSN	0378-4347 ; 1570-0232 ; 1387-2273
DOI	10.1016/j.jchromb.2016.01.007
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 813: Show issues

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Article: [Effects of parenteral nutrition on cell cycle kinetics in gastric cancer patients].

Cao, W X

Zhonghua zhong liu za zhi [Chinese journal of oncology

1992 Volume 14, Issue 6, Page(s) 418–420

Abstract: Studies were made on tumor growth changes by 1-week supplementary parenteral nutrition in undernourished advanced gastric cancer patients. Biopsy of the normal mucosa and cancerous tissue were taken through endoscope before and one week after parenteral ... ...

Abstract	Studies were made on tumor growth changes by 1-week supplementary parenteral nutrition in undernourished advanced gastric cancer patients. Biopsy of the normal mucosa and cancerous tissue were taken through endoscope before and one week after parenteral nutrition and at the time of operation. Percentage of cells in various phases were analyzed by flow cytometry. The frequency of S and proliferative phases were markedly increased (P < 0.05) in cancerous tissue but not in the normal mucosa. These results demonstrate that a stimulating effect may be present in tumor cell kinetics and hence, the use of a cycle-specific chemotherapeutic agent is indicated.
MeSH term(s)	Aneuploidy ; Cell Cycle ; DNA, Neoplasm/genetics ; Female ; Flow Cytometry ; Gastric Mucosa/pathology ; Humans ; Male ; Middle Aged ; Parenteral Nutrition/adverse effects ; S Phase ; Stomach Neoplasms/pathology ; Stomach Neoplasms/therapy
Chemical Substances	DNA, Neoplasm
Language	Chinese
Publishing date	1992-11
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	603424-x
ISSN	0253-3766
ISSN	0253-3766
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.B 2277: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 321: Show issues

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Article: [Effects of parenteral nutrition on protein metabolism in patients with gastric cancer].

Cao, W X

Zhonghua wai ke za zhi [Chinese journal of surgery

1990 Volume 28, Issue 12, Page(s) 742–4, 782–3

Abstract: Unlabelled: In this study, the changes of protein kinetics in patients with gastric cancer were determined using by 15N-glycine tracer assay before and after parenteral nutrition. The results showed that the protein turnover especially anabolic rate may ...

Abstract	Unlabelled: In this study, the changes of protein kinetics in patients with gastric cancer were determined using by 15N-glycine tracer assay before and after parenteral nutrition. The results showed that the protein turnover especially anabolic rate may be enhanced by parenteral nutritional support. The pre- and post operative increase of protein anabolic rate was more than that of the catabolic rate, about 10% and 88% respectively. This phenomenon could be explained as following, (1). the abnormal metabolism in cancer patients was extinguished after the tumor resection; (2). the supplementation of the nitrogen was increased; (3). branched chain amino acids could be used as energy resource for muscle metabolism and to improve protein synthesis while its breakdown was inhibited. Conclusion: It is necessary to administer the parenteral nutritional support to patients with malnutrition before operation. With adequate nitrogen and calorie supply, negative nitrogen balance could be improved.
MeSH term(s)	Adult ; Aged ; Amino Acids, Branched-Chain/metabolism ; Humans ; Kinetics ; Male ; Middle Aged ; Parenteral Nutrition, Total ; Preoperative Care ; Prospective Studies ; Proteins/metabolism ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/therapy
Chemical Substances	Amino Acids, Branched-Chain ; Proteins
Language	Chinese
Publishing date	1990-12
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	604573-x
ISSN	0529-5815
ISSN	0529-5815
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.B 2469: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 218: Show issues

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Article: Assessing newly developed and published vegetation indices for estimating rice leaf nitrogen concentration with ground- and space-based hyperspectral reflectance

Tian, Y.C / Yao, X / Yang, J / Cao, W.X / Hannaway, D.B / Zhu, Y

Field crops research. 2011 Jan. 31, v. 120, no. 2

2011

Abstract: Non-destructive and quick assessment of leaf nitrogen (N) status is important for dynamic management of nitrogen nutrition and productivity forecast in crop production. This research was undertaken to make a systematic analysis on the quantitative ... ...

Abstract	Non-destructive and quick assessment of leaf nitrogen (N) status is important for dynamic management of nitrogen nutrition and productivity forecast in crop production. This research was undertaken to make a systematic analysis on the quantitative relationship of leaf nitrogen concentrations (LNCs) to different hyperspectral vegetation indices with multiple field experiments under varied nitrogen rates and varied types in rice (Oryza sativa L.). The results showed that some published indices had good relations with LNC such as two-band indices, R ₇₅₀/R ₇₁₀ (ZM), Gitelson and Merzlyak index two (GM-2), R ₇₃₅/R ₇₂₀ (RI-1dB), R ₇₃₈/R ₇₂₀ (RI-2dB) and the normalized difference red edge index (NDRE), three-band indices, adjusted normalized index 705 (mND705), physiological reflectance index c (PRIc), terrestrial chlorophyll index (MTCI), and red edge position derived with four point linear interpolation (REP_LI). Three-band indices performed better than two-band indices, with MTCI exhibiting the best logarithmic relation to LNC in rice. Then, hyper-spectral vegetation indices computed with random two bands (λ ₁ and λ ₂) from 400 to 2500nm range were related to LNC of rice. The results indicated that two-band indices combined with bands of 550-600nm and 500-550nm in green region had good relationships with LNC, and simple ratio index SR(533,565) performed the best in all two-band indices, similar to the published three-band indices (mND705, PRIc and MTCI). New three-band indices R ₄₃₄/(R ₄₉₆ + R ₄₀₁) and R ₇₀₅/(R ₇₁₇ + R ₄₉₁) were proposed for prediction of LNC with improved ability over the SR(533,565) and published spectral indices. Moreover, R ₇₀₅/(R ₇₁₇ + R ₄₉₁) performed well in all the data from ground spectra, modeled AVIRIS and Hyperion spectra, and acquired Hyperion image hyperspectra. The R ₄₃₄/(R ₄₉₆ + R ₄₀₁) also exhibited well in both ground and modeled AVIRIS and Hyperion image spectra, but could not be tested with the acquired Hyperion image because of the absence in radiometric calibration of the bands less than 416nm. Overall, the newly developed three-band spectral index R ₇₀₅/(R ₇₁₇ + R ₄₉₁) should be a good indicator of LNC at ground and space scales in rice. Yet, these new indices still need to be tested with more remote sensors based on ground, airborne and spaceborne, and verified widely in other ecological locations involving different cultivars and production systems.
Keywords	Oryza sativa ; chlorophyll ; crop production ; cultivars ; field experimentation ; hyperspectral imagery ; image analysis ; leaves ; nitrogen ; nitrogen content ; production technology ; quantitative analysis ; reflectance ; remote sensing ; rice ; vegetation
Language	English
Dates of publication	2011-0131
Size	p. 299-310.
Publishing place	[Amsterdam]: Elsevier
Document type	Article
ZDB-ID	435684-6
ISSN	0378-4290
ISSN	0378-4290
DOI	10.1016/j.fcr.2010.11.002
Database	NAL-Catalogue (AGRICOLA)

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Article: Monitoring leaf nitrogen status with hyperspectral reflectance in wheat

Feng, W / Yao, X / Zhu, Y / Tian, Y.C / Cao, W.X

European journal of agronomy. 2008 Apr., v. 28, no. 3

2008

Abstract: The objectives of this study were to determine the relationships of leaf nitrogen concentration on a leaf dry weight basis (LNC) and leaf nitrogen accumulation per unit soil area (LNA) to ground-based canopy hyperspectral reflectance and derivative ... ...

Abstract	The objectives of this study were to determine the relationships of leaf nitrogen concentration on a leaf dry weight basis (LNC) and leaf nitrogen accumulation per unit soil area (LNA) to ground-based canopy hyperspectral reflectance and derivative parameters, and to establish quantitative models for real-time monitoring of leaf N status with key hyperspectral bands and estimation indices in wheat (Triticum aestivum L.). Three field experiments were conducted with different N application rates and wheat cultivars across three growing seasons, and time-course measurements were taken on canopy hyperspectral reflectance, LNC and leaf dry weights under the various treatments. The results showed that LNC and LNA in wheat increased with increasing nitrogen fertilization rates, and changes in canopy hyperspectral reflectance under varied N rates were all highly significant, with consistent patterns across the different cultivars and years. The sensitive spectral bands occurred mostly within visible light and near infrared regions, and a close correlation existed between red-edge district and LNC or LNA. An integrated linear regression equation of LNC to spectral parameters REIPle and λ o well described the dynamic pattern of LNC changes in wheat, giving the determination of coefficients (R ²) as 0.831 and 0.834, and the standard errors (SE) as 0.405 and 0.403, respectively. The hyperspectral parameters MSS-SARVI and FD742 were linearly related to LNA, with R ² as 0.861 and 0.873, and SE as 1.11 and 1.06, respectively. When independent data were used to test the derived equations, the R ² values between the measured and estimated LNC from spectral parameters REIPle and mND705 were 0.752 and 0.695, with the average relative errors (RE) as 14.4% and 16.5%, respectively. For spectral parameters FD742 and SDr/SDb, the R ² values between the measured and estimated LNA were 0.872 and 0.828, with RE as 14.1% and 15.2%, respectively. The high fit between the measured and estimated values indicated that the present models based on hyperspectral reflectance could be used for reliable estimation of the leaf N status in wheat plant under different growing conditions.
Keywords	Triticum aestivum ; wheat ; leaves ; nitrogen content ; nutrient uptake ; hyperspectral imagery ; reflectance ; models ; field experimentation ; nitrogen fertilizers ; fertilizer rates ; cultivars ; temporal variation ; calibration ; equations ; canopy ; regression analysis ; monitoring ; measurement ; China
Language	English
Dates of publication	2008-04
Size	p. 394-404.
Publishing place	Amsterdam, the Netherlands: Elsevier Science Pub. Co.
Document type	Article
ZDB-ID	1157136-6
ISSN	1873-7331 ; 1161-0301
ISSN (online)	1873-7331
ISSN	1161-0301
DOI	10.1016/j.eja.2007.11.005
Database	NAL-Catalogue (AGRICOLA)

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Z 5704: Show issues

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Article: Assessing newly developed and published vegetation indices for estimating rice leaf nitrogen concentration with ground- and space-based hyperspectral reflectance

Tian, Y. C. / Yao, X. / Yang, J. / Cao, W. X. / Hannaway, D. B. / Zhu, Y.

Field crops research

2011 Volume 120, Issue 2, Page(s) 299

Document type	Article
ZDB-ID	435684-6
ISSN	0378-4290
Database	Current Contents Nutrition, Environment, Agriculture

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