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  1. Article ; Online: Reply to "Re: Survival and Tolerability of Transarterial Chemoembolization in Greater Versus less than 70 Years of Age Patients with Unresectable Hepatocellular Carcinoma-A Propensity Analysis".

    Mosconi, Cristina / Gramenzi, Annagiulia / Cappelli, Alberta / Biselli, Maurizio / Golfieri, Rita

    Cardiovascular and interventional radiology

    2021  Volume 44, Issue 7, Page(s) 1135–1136

    MeSH term(s) Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/therapy ; Chemoembolization, Therapeutic ; Humans ; Liver Neoplasms/mortality ; Liver Neoplasms/therapy ; Propensity Score
    Language English
    Publishing date 2021-03-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 603082-8
    ISSN 1432-086X ; 0342-7196 ; 0174-1551
    ISSN (online) 1432-086X
    ISSN 0342-7196 ; 0174-1551
    DOI 10.1007/s00270-021-02799-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Hepatopancreatoduodenectomy for locally advanced perihilar cholangiocarcinoma: A case report and a plea not to underestimate surgical resectability.

    Fallani, Guido / Cappelli, Alberta / Siniscalchi, Antonio / Vasuri, Francesco / Germinario, Giuliana / Ravaioli, Matteo

    International journal of surgery case reports

    2022  Volume 98, Page(s) 107495

    Language English
    Publishing date 2022-08-09
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2022.107495
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Update of the Bologna Experience in Radioembolization of Intrahepatic cholangiocarcinoma.

    Mosconi, Cristina / Cacioppa, Laura Maria / Cappelli, Alberta / Gramenzi, Anna Giulia / Vara, Giulio / Modestino, Francesco / Renzulli, Matteo / Golfieri, Rita

    Technology in cancer research & treatment

    2023  Volume 22, Page(s) 15330338231155690

    Abstract: Background: Intrahepatic cholangiocarcinoma (ICC) is the second most common primitive liver cancer and is rising in incidence worldwide. Given its low survival and resectability rates, locoregional therapies such as Yttrium-90 transarterial ... ...

    Abstract Background: Intrahepatic cholangiocarcinoma (ICC) is the second most common primitive liver cancer and is rising in incidence worldwide. Given its low survival and resectability rates, locoregional therapies such as Yttrium-90 transarterial radioembolization (Y-TARE) are increasingly being employed. This retrospective study aim was to confirm and update our previous results about overall survival (OR), safety, and efficacy of Y-TARE in patients with unresectable/recurrent ICC.
    Materials and methods: OS was evaluated as primary endpoint while radiological tumor response at 3 months, based on Response Evaluation Criteria in Solid Tumors (RECIST) 1.1, was considered as secondary endpoint.
    Results: Over a total of 49 patients, the overall median survival was 16 months (27-41 months, 95% confidence interval [CI]) from Y-TARE procedure. A significantly longer survival was recorded in naive patients compared to patients previously submitted to any type of liver-directed treatment and radical surgery (18 vs 14 months,
    Conclusions: In unresectable and recurrent ICC, Y-TARE confirms its safety and its potential in increasing OS, especially in naive patients.
    MeSH term(s) Humans ; Retrospective Studies ; Treatment Outcome ; Yttrium Radioisotopes/adverse effects ; Bile Duct Neoplasms ; Cholangiocarcinoma/pathology ; Bile Ducts, Intrahepatic/pathology ; Liver Neoplasms/radiotherapy ; Liver Neoplasms/pathology
    Chemical Substances Yttrium Radioisotopes
    Language English
    Publishing date 2023-03-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2146365-7
    ISSN 1533-0338 ; 1533-0346
    ISSN (online) 1533-0338
    ISSN 1533-0346
    DOI 10.1177/15330338231155690
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Bone echinococcosis with hip localization: A case report with evaluation of imaging features.

    Martinese, Giuseppe / Lucidi, Vincenzo / Masi, Paola Di / Adduci, Francesco / Cappelli, Alberta / Renzulli, Matteo / De Paolis, Massimiliano / Fiore, Michele / Golfieri, Rita

    Radiology case reports

    2022  Volume 17, Issue 9, Page(s) 3389–3394

    Abstract: Hydatid disease (HD) is a zoonotic parasitic disease caused by the larvae of Echinococcus. Bone echinococcosis is rare, accounting for 0.5% to 4% of all echinococcosis. We describe a particular case of pelvic echinoccosis. A 29-year-old man initially ... ...

    Abstract Hydatid disease (HD) is a zoonotic parasitic disease caused by the larvae of Echinococcus. Bone echinococcosis is rare, accounting for 0.5% to 4% of all echinococcosis. We describe a particular case of pelvic echinoccosis. A 29-year-old man initially presents with pain in his left hip for several years. After an accidental fall from a tree, he suffered a fracture of the left acetabulum. X-rays and CT scans showed an osteolytic area of the acetabulum with bony cortical interruption. MR imaging demonstrated extensive area of osteostructural alteration of the iliac wing and the
    Language English
    Publishing date 2022-07-19
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2022.06.065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Case report: PSMA PET/CT addresses the correct diagnosis in a patient with metastatic prostate cancer despite negative core biopsies and mpMRI. A diagnostic challenge.

    Vetrone, Luigia / Cuzzani, Giulia / Mei, Riccardo / Zanoni, Lucia / Bertaccini, Alessandro / Bianchi, Lorenzo / Castellucci, Paolo / Gaudiano, Caterina / Cappelli, Alberta / Giunchi, Francesca / Fanti, Stefano

    Frontiers in oncology

    2023  Volume 13, Page(s) 1101221

    Abstract: This is a case of [ ...

    Abstract This is a case of [
    Language English
    Publishing date 2023-02-07
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1101221
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Radiomic Features from Post-Operative

    Cuicchi, Dajana / Mottola, Margherita / Castellucci, Paolo / Bevilacqua, Alessandro / Cattabriga, Arrigo / Cocozza, Maria Adriana / Cardelli, Stefano / Dajti, Gerti / Mattoni, Susanna / Golfieri, Rita / Fanti, Stefano / Cappelli, Alberta / Coppola, Francesca / Poggioli, Gilberto

    Journal of clinical medicine

    2023  Volume 12, Issue 5

    Abstract: Locally Recurrent Rectal Cancer (LRRC) remains a major clinical concern; it rapidly invades pelvic organs and nerve roots, causing severe symptoms. Curative-intent salvage therapy offers the only potential for cure but it has a higher chance of success ... ...

    Abstract Locally Recurrent Rectal Cancer (LRRC) remains a major clinical concern; it rapidly invades pelvic organs and nerve roots, causing severe symptoms. Curative-intent salvage therapy offers the only potential for cure but it has a higher chance of success when LRRC is diagnosed at an early stage. Imaging diagnosis of LRRC is very challenging due to fibrosis and inflammatory pelvic tissue, which can mislead even the most expert reader. This study exploited a radiomic analysis to enrich, through quantitative features, the characterization of tissue properties, thus favoring an accurate detection of LRRC by Computed Tomography (CT) and 18F-FDG-Positron Emission Tomography/CT (PET/CT). Of 563 eligible patients undergoing radical resection (R0) of primary RC, 57 patients with suspected LRRC were included, 33 of which were histologically confirmed. After manually segmenting suspected LRRC in CT and PET/CT, 144 Radiomic Features (RFs) were generated, and RFs were investigated for univariate significant discriminations (Wilcoxon rank-sum test,
    Language English
    Publishing date 2023-03-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12052058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Uterine Artery Embolization for the Treatment of Symptomatic Uterine Fibroids of Different Sizes: A Single Center Experience.

    Cappelli, Alberta / Mosconi, Cristina / Cocozza, Maria Adriana / Brandi, Nicolò / Bartalena, Laura / Modestino, Francesco / Galaverni, Maria Cristina / Vara, Giulio / Paccapelo, Alexandro / Pizzoli, Gloria / Villa, Gioia / Seracchioli, Renato / Renzulli, Matteo

    Journal of personalized medicine

    2023  Volume 13, Issue 6

    Abstract: The present study aimed to evaluate the clinical and radiological 1-year outcomes of uterine artery embolization (UAE) performed in a selected population of women with symptomatic myomas and who do not wish to conceive. Between January 2004 and January ... ...

    Abstract The present study aimed to evaluate the clinical and radiological 1-year outcomes of uterine artery embolization (UAE) performed in a selected population of women with symptomatic myomas and who do not wish to conceive. Between January 2004 and January 2018, a total of 62 patients with pre-menopausal status and with no wish to conceive in the future underwent UAE for the treatment of symptomatic fibroids. All the patients underwent magnetic resonance imaging (MRI) and/or transvaginal ultrasonography (TV-US) before and after the procedure at 1-year follow-up. Clinical and radiological parameters were recorded, stratifying the population into 3 groups according to the size of the dominant myoma (group 1: <50 mm; group 2: ≥50 and ≤80 mm; group 3: >80 mm). Mean fibroid diameter was significantly reduced (42.6% ± 21.6%) at 1-year follow-up, with excellent improvements in terms of both symptoms and quality of life. No significant difference was observed regarding baseline dimension and the number of myomas. No major complications were reported (2.5%). The present study confirms the safety and efficacy of UAE in the treatment of symptomatic fibroids in pre-menopausal women with no desire to conceive.
    Language English
    Publishing date 2023-05-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm13060906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Validation of response to yttrium-90 radioembolization for hepatocellular carcinoma with portal vein invasion.

    Mosconi, Cristina / Cucchetti, Alessandro / Pettinato, Cinzia / Golfieri, Rita / Cappelli, Alberta

    Journal of hepatology

    2018  Volume 69, Issue 1, Page(s) 259–260

    MeSH term(s) Carcinoma, Hepatocellular ; Embolization, Therapeutic ; Humans ; Liver Neoplasms ; Portal Vein ; Prognosis ; Yttrium Radioisotopes
    Chemical Substances Yttrium Radioisotopes ; Yttrium-90 (1K8M7UR6O1)
    Language English
    Publishing date 2018-03-14
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2018.02.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Transarterial Chemoembolization and Radioembolization for Unresectable Intrahepatic Cholangiocarcinoma-a Systemic Review and Meta-Analysis.

    Mosconi, Cristina / Solaini, Leonardo / Vara, Giulio / Brandi, Nicolò / Cappelli, Alberta / Modestino, Francesco / Cucchetti, Alessandro / Golfieri, Rita

    Cardiovascular and interventional radiology

    2021  Volume 44, Issue 5, Page(s) 728–738

    Abstract: Purpose: Intrahepatic cholangiocarcinoma (ICC) has a poor prognosis, when unresectable; therefore, intra-arterial therapies (IAT) such as trans-arterial chemoembolization (TACE) and trans-arterial radioembolization (TARE) have been employed. With the ... ...

    Abstract Purpose: Intrahepatic cholangiocarcinoma (ICC) has a poor prognosis, when unresectable; therefore, intra-arterial therapies (IAT) such as trans-arterial chemoembolization (TACE) and trans-arterial radioembolization (TARE) have been employed. With the present systematic review and meta-analysis, we aimed to analyse published studies to understand if one IAT can be superior to the alternative.
    Materials and methods: A systematic search of PubMed and Web of Science databases was performed for articles published until 1 March 2020 relevant to IAT for ICC. Overall survival was the primary end point. Occurrence of clinical adverse events and tumour overall response were secondary outcome measures.
    Results: A total of 31 articles (of 793, n.1695 patients) were selected for data extraction, 13 were on TACE (906 patients) and 18 were on TARE (789 patients). Clinical and tumour characteristics showed moderate heterogeneity between the two groups. The median survival after TACE was 14.2 months while after TARE was 13.5 months (95%C.I.: 11.4-16.1). The survival difference was small (d = 0.112) at 1 year and negligible at 2 years (d = 0.028) and at 3 years (d = 0.049). The radiological objective response after TACE was 20.6% and after TARE was 19.3% (d = 0.032). Clinical adverse events occurred in 58.5% after TACE, more frequently than after TARE (43.0%, d = 0.314).
    Conclusion: In conclusion, IATs are promising treatments for improving outcomes for patients with unresectable ICC. To date, TACE and TARE provide similar good outcomes, except for adverse events. Therefore, the decision about techniques is determined by ability to utilize these resources and patient specific factors (liver function or lesion dimension).
    MeSH term(s) Bile Duct Neoplasms/therapy ; Bile Ducts, Intrahepatic ; Chemoembolization, Therapeutic/methods ; Cholangiocarcinoma/therapy ; Humans ; Yttrium Radioisotopes/therapeutic use
    Chemical Substances Yttrium Radioisotopes
    Language English
    Publishing date 2021-03-11
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 603082-8
    ISSN 1432-086X ; 0342-7196 ; 0174-1551
    ISSN (online) 1432-086X
    ISSN 0342-7196 ; 0174-1551
    DOI 10.1007/s00270-021-02800-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reply to External validation of an individual prognostic calculator after trans-arterial chemo-embolization for hepatocellular carcinoma.

    Cucchetti, Alessandro / Cappelli, Alberta / Golfieri, Rita

    Liver international : official journal of the International Association for the Study of the Liver

    2016  Volume 36, Issue 8, Page(s) 1232

    Language English
    Publishing date 2016-08
    Publishing country United States
    Document type Letter
    ZDB-ID 2102783-3
    ISSN 1478-3231 ; 1478-3223
    ISSN (online) 1478-3231
    ISSN 1478-3223
    DOI 10.1111/liv.13145
    Database MEDical Literature Analysis and Retrieval System OnLINE

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