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  1. Book ; Online: Using Ostraca in the Ancient World. New Discoveries and Methodologies

    Caputo, Clementina / Lougovaya, Julia

    2021  

    Keywords papyrology ; Egyptology ; ostraca ; Ancient Egypt
    Size 1 electronic resource (251 pages)
    Publisher De Gruyter
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021026534
    ISBN 9783110712902 ; 3110712903
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Using Ostraca in the Ancient World New Discoveries and Methodologies

    Caputo, Clementina / Lougovaya, Julia

    2020  

    Keywords Classical texts ; Classical history / classical civilisation ; Egyptian archaeology / Egyptology ; Classical Greek & Roman archaeology ; ostraca ; papyrology ; Egyptology ; Ancient Egypt
    Size 1 electronic resource (245 pages)
    Publisher De Gruyter
    Publishing place Berlin/Boston
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021027647
    ISBN 9783110712902 ; 3110712903
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Release of calcium into the myofibrillar space in response to active shortening of striated muscle.

    Edman, K A P / Caputo, C

    Acta physiologica (Oxford, England)

    2017  Volume 221, Issue 2, Page(s) 142–148

    Abstract: Aim: The study was undertaken to explore whether shortening of striated muscle during activity is associated with release of bound Ca: Methods: The experiments were carried out on single muscle fibres isolated from the anterior tibialis muscle of ... ...

    Abstract Aim: The study was undertaken to explore whether shortening of striated muscle during activity is associated with release of bound Ca
    Methods: The experiments were carried out on single muscle fibres isolated from the anterior tibialis muscle of Rana temporaria. The fibres were loaded with the calcium sensitive indicator Fluo-3. The fibres, stimulated to produce a partially fused isometric tetanus, were subjected to a shortening ramp or, alternatively, to a stretch ramp during activity while force, fibre length, sarcomere length and the Fluo-3 signal were recorded.
    Results: A shortening ramp performed during a partially fused tetanus caused an increase in the myofibrillar free calcium concentration and produced, simultaneously, a decrease in active force. The isometric force recovered gradually after the shortening ramp, while the intracellular Ca
    Conclusion: The results provide evidence that the myosin cross-bridges interact with the calcium binding sites on the thin filaments during active shortening, causing sustained release of calcium and reduced contractile strength.
    Language English
    Publishing date 2017-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2218636-0
    ISSN 1748-1716 ; 1748-1708
    ISSN (online) 1748-1716
    ISSN 1748-1708
    DOI 10.1111/apha.12876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Suprasellar keratinous cyst: A case report and review on its radiological features and treatment outcome.

    Huo, C W / Caputo, C / Wang, Y Y

    Surgical neurology international

    2018  Volume 9, Page(s) 15

    Abstract: Background: Keratinous or epidermoid cysts (ECs) are encapsulated lesions lined by squamous cell epithelium. They comprise approximately 1% of intracranial lesions. Contrary to dermoid cysts, they lack dermal elements such as sebaceous or apocrine ... ...

    Abstract Background: Keratinous or epidermoid cysts (ECs) are encapsulated lesions lined by squamous cell epithelium. They comprise approximately 1% of intracranial lesions. Contrary to dermoid cysts, they lack dermal elements such as sebaceous or apocrine glands and hair follicles. The sellar region is the second most common intracranial site following the cerebellopontine angle. Here, we report a case of EC in a patient who complained of endocrine disturbances. We also performed a systematic review on previously published cases to analyze clinical and radiological characteristics and report the treatment outcomes of suprasellar ECs.
    Case description: A 42-year-old woman presented with a one-year history of amenorrhea, weight gain, severe headache, and visual disturbances for 6 months. Work-up identified an elevated prolactin level and a temporal field defect of the right eye. Magnetic resonance imaging (MRI) showed a cystic suprasellar lesion pushing on the optic chiasm. She underwent endoscopic trans-sphenoidal surgery, which confirmed a keratinous cyst on histology. Postoperatively, complete resection was confirmed on imaging. She did well although her hospital stay was prolonged due to diabetes insipidus and hypocortisolism.
    Conclusion: Chronic endocrine disturbances can be the presenting complaints of a suprasellar EC, whose T1-weighted MRI appearance can be non-specific, mimicking other differential diagnoses, such as a Rathke's cleft cyst. However, the T2-weighted MRI appearances of ECs are generally hyper-intense and lesions show diffusion restriction. Treatment is surgical and yields good outcomes in most cases reported.
    Language English
    Publishing date 2018-01-22
    Publishing country United States
    Document type Case Reports
    ISSN 2229-5097
    ISSN 2229-5097
    DOI 10.4103/sni.sni_269_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A robotic arm for safe and accurate control of biomedical equipment during COVID-19.

    Iadanza, Ernesto / Pasqua, Giammarco / Piaggio, Davide / Caputo, Corrado / Gherardelli, Monica / Pecchia, Leandro

    Health and technology

    2023  Volume 13, Issue 2, Page(s) 285–300

    Abstract: Purpose: Hospital facilities and social life, along with the global economy, have been severely challenged by COVID-19 since the World Health Organization (WHO) declared it a pandemic in March 2020. Since then, countless ordinary citizens, as well as ... ...

    Abstract Purpose: Hospital facilities and social life, along with the global economy, have been severely challenged by COVID-19 since the World Health Organization (WHO) declared it a pandemic in March 2020. Since then, countless ordinary citizens, as well as healthcare workers, have contracted the virus by just coming into contact with infected surfaces. In order to minimise the risk of getting infected by contact with such surfaces, our study aims to design, prototype, and test a new device able to connect users, such as common citizens, doctors or paramedics, with either common-use interfaces (e.g., lift and snack machine keyboards, traffic light push-buttons) or medical-use interfaces (e.g., any medical equipment keypad).
    Method: To this purpose, the device was designed with the help of Unified Modelling Language (UML) schemes, and was informed by a risk analysis, that highlighted some of its essential requirements and specifications. Consequently, the chosen constructive solution of the robotic system, i.e., a robotic-arm structure, was designed and manufactured using computer-aided design and 3D printing.
    Result: The final prototype included a properly programmed micro-controller, linked via Bluetooth to a multi-platform mobile phone app, which represents the user interface. The system was then successfully tested on different physical keypads and touch screens. Better performance of the system can be foreseen by introducing improvements in the industrial production phase.
    Conclusion: This first prototype paves the way for further research in this area, allowing for better management and preparedness of next pandemic emergencies.
    Language English
    Publishing date 2023-01-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2581463-1
    ISSN 2190-7196 ; 2190-7188
    ISSN (online) 2190-7196
    ISSN 2190-7188
    DOI 10.1007/s12553-022-00715-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Improving Management of Portal Hypertension: The Potential Benefit of Non-Etiological Therapies in Cirrhosis.

    Bitto, Niccolò / Ghigliazza, Gabriele / Lavorato, Stanislao / Caputo, Camilla / La Mura, Vincenzo

    Journal of clinical medicine

    2023  Volume 12, Issue 3

    Abstract: Portal hypertension is the consequence of cirrhosis and results from increased sinusoidal vascular resistance and hepatic blood inflow. Etiological therapies represent the first intervention to prevent a significant increase in portal pressure due to ... ...

    Abstract Portal hypertension is the consequence of cirrhosis and results from increased sinusoidal vascular resistance and hepatic blood inflow. Etiological therapies represent the first intervention to prevent a significant increase in portal pressure due to chronic liver damage. However, other superimposed pathophysiological drivers may worsen liver disease, including inflammation, bacterial translocation, endothelial dysfunction, and hyperactivation of hemostasis. These mechanisms can be targeted by a specific class of drugs already used in clinical practice. Albumin, rifaximin, statins, aspirin, and anticoagulants have been tested in cirrhosis and were a topic of discussion in the last Baveno consensus as non-etiological therapies. Based on the pathogenesis of portal hypertension in cirrhosis, our review summarizes the main mechanisms targeted by these drugs as well as the clinical evidence that considers them a valid complementary option to manage patients with cirrhosis and portal hypertension.
    Language English
    Publishing date 2023-01-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12030934
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Headache Improvement Following Endoscopic Resection of Pituitary Adenomas.

    Delport, Ryan / King, James / Castle-Kirszbaum, Mendel / Goldschlager, Tony / Caputo, Carmela / Wang, Yi Yuen

    World neurosurgery

    2023  Volume 176, Page(s) e456–e461

    Abstract: Background: Headache is a common symptom in patients with pituitary adenomas. Research on whether resection of pituitary adenomas via the endoscopic endonasal approach (EEA) affects headaches is limited, and the pathophysiology of headaches associated ... ...

    Abstract Background: Headache is a common symptom in patients with pituitary adenomas. Research on whether resection of pituitary adenomas via the endoscopic endonasal approach (EEA) affects headaches is limited, and the pathophysiology of headaches associated with pituitary adenomas remains unclear. This study aimed to determine if resection of pituitary adenomas via the EEA improves headaches and investigate factors that may be associated with headaches in patients with pituitary adenoma.
    Methods: A prospectively collected database of 122 patients undergoing resection of pituitary adenoma via the EEA was analyzed. Patient-reported headache severity was collected prospectively using the Headache Impact Test (HIT-6) at preoperative baseline and 4 postoperative time points (3 weeks, 6 weeks, 3 months, and 6 months).
    Results: Adenoma size and subtype, cavernous sinus invasion, and hormonal status were not associated with preoperative headache burden. In patients with preoperative headaches (HIT-6 score >36), significant decreases in HIT-6 score were observed postoperatively at 6 weeks (5.5-point improvement, 95% CI 1.27-9.78, P < 0.01), 3 months (3.6-point improvement, 95% CI 0.01-7.18, P < 0.05), and 6 months (7.5-point improvement, 95% CI 3.43-11.46, P < 0.01). The only factor associated with headache improvement was cavernous sinus invasion (P = 0.003). Adenoma size and subtype and hormonal status were not associated with postoperative headache burden.
    Conclusions: Resection via the EEA is associated with significant improvement in headache-related impact on patient functioning from ≥6 weeks after surgery. Patients with cavernous sinus invasion are more likely to experience improvement in headaches. The mechanism of headaches associated with pituitary adenoma still requires clarification.
    MeSH term(s) Humans ; Pituitary Neoplasms/complications ; Pituitary Neoplasms/surgery ; Adenoma/complications ; Adenoma/surgery ; Endoscopy ; Headache/complications ; Nose/surgery ; Treatment Outcome ; Retrospective Studies
    Language English
    Publishing date 2023-06-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.05.082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Design and planning of flexible mobile Micro-Grids using Deep Reinforcement Learning

    Caputo, Cesare / Cardin, Michel-Alexandre / Ge, Pudong / Teng, Fei / Korre, Anna / Antonio del Rio Chanona, Ehecatl

    Applied Energy. 2023 Apr., v. 335 p.120707-

    2023  

    Abstract: Ongoing risks from climate change have significantly impacted the livelihood of global nomadic communities and are likely to lead to increased migratory movements in coming years. As a result, mobility considerations are becoming increasingly important ... ...

    Abstract Ongoing risks from climate change have significantly impacted the livelihood of global nomadic communities and are likely to lead to increased migratory movements in coming years. As a result, mobility considerations are becoming increasingly important in energy systems planning, particularly to achieve energy access in developing countries. Advanced “Plug and Play” control strategies have been recently developed with such a decentralized framework in mind, allowing easier interconnection of nomadic communities, both to each other and to the main grid. Considering the above, the design and planning strategy of a mobile multi-energy supply system for a nomadic community is investigated in this work. Motivated by the scale and dimensionality of the associated uncertainties, impacting all major design and decision variables over the 30-year planning horizon, Deep Reinforcement Learning (DRL) Flexibility Analysis is implemented for the design and planning problem. DRL based solutions are benchmarked against several rigid baseline design options to compare expected performance under uncertainty. The results on a case study for ger communities in Mongolia suggest that mobile nomadic energy systems can be both technically and economically feasible, particularly when considering flexibility, although the degree of spatial dispersion among households is an important limiting factor. Additionally, the DRL based policies lead to the development of dynamic evolution and adaptability strategies, which can be used by the targeted communities under a very wide range of potential scenarios. Key economic, sustainability and resilience indicators such as Cost, Equivalent Emissions and Total Unmet Load are measured, suggesting potential improvements compared to available baselines of up to 25%, 67% and 76%, respectively. Finally, the decomposition of values of flexibility and plug and play operation is presented using a variation of real options theory, with important implications for both nomadic communities and policymakers focused on enabling their energy access.
    Keywords case studies ; climate change ; economic feasibility ; energy ; livelihood ; migratory behavior ; uncertainty ; Mongolia ; Deep Reinforcement Learning ; Energy Systems Design ; Flexibility in Design ; Mobile Micro-Grids Systems ; Real Options Analysis ; Uncertainty and Risk Analysis
    Language English
    Dates of publication 2023-04
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Use and reproduction
    ZDB-ID 2000772-3
    ISSN 0306-2619
    ISSN 0306-2619
    DOI 10.1016/j.apenergy.2023.120707
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Letter to the Editor: "A Meta-Analysis of the Prevalence of Cardiac Valvulopathy in Patients With Hyperprolactinemia Treated With Cabergoline".

    Caputo, Carmela / Inder, Warrick J

    The Journal of clinical endocrinology and metabolism

    2018  Volume 104, Issue 10, Page(s) 4319–4320

    MeSH term(s) Cabergoline ; Ergolines ; Heart Valve Diseases ; Humans ; Hyperprolactinemia ; Prevalence
    Chemical Substances Ergolines ; Cabergoline (LL60K9J05T)
    Language English
    Publishing date 2018-08-06
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/jc.2019-00577
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Effect of calcium deprivation on frog skeletal muscles at different pH values.

    Argibay, J / Caputo, C

    The Journal of membrane biology

    2013  Volume 4, Issue 1, Page(s) 68–73

    Abstract: Whole sartorius muscles from the frog were exposed to calcium-free solutions at different pH values. The depolarizations caused by these solutions were measured 1 hr after the solution change. When the pH was 7.2, the mean depolarization was 8 mV. At pH ... ...

    Abstract Whole sartorius muscles from the frog were exposed to calcium-free solutions at different pH values. The depolarizations caused by these solutions were measured 1 hr after the solution change. When the pH was 7.2, the mean depolarization was 8 mV. At pH values of 5.1 and 8.5, the mean depolarizations were 1 and 17 mV, respectively. Similar experiments were carried out with solutions in which the main anion was sulfate instead of chloride. In these cases, the depolarization values caused by calcium deprivation at pH values of 7.2, 5.5, and 8.5 were 11, 4, and 20 mV, respectively.
    Language English
    Publishing date 2013-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3082-x
    ISSN 1432-1424 ; 0022-2631
    ISSN (online) 1432-1424
    ISSN 0022-2631
    DOI 10.1007/BF02431962
    Database MEDical Literature Analysis and Retrieval System OnLINE

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