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  1. Article ; Online: Oral health, hypertension and cardiovascular diseases.

    Carasol, M / Muñoz Aguilera, E / Ruilope, L M

    Hipertension y riesgo vascular

    2023  Volume 40, Issue 4, Page(s) 167–170

    MeSH term(s) Humans ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/prevention & control ; Oral Health ; Hypertension/epidemiology ; Risk Factors
    Language English
    Publishing date 2023-05-10
    Publishing country Spain
    Document type Journal Article
    ISSN 1989-4805
    ISSN (online) 1989-4805
    DOI 10.1016/j.hipert.2023.04.001
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  2. Article ; Online: The association between periodontitis and cerebrovascular disease, and dementia. Scientific report of the working group of the Spanish Society of Periodontology and the Spanish Society of Neurology.

    Leira, Y / Vivancos, J / Diz, P / Martín, Á / Carasol, M / Frank, A

    Neurologia

    2024  Volume 39, Issue 3, Page(s) 302–311

    Abstract: Objective: This article reviews the scientific evidence on the relationship between periodontitis and neurological disease, and particularly cerebrovascular disease and dementia. We also issue a series of recommendations regarding the prevention and ... ...

    Abstract Objective: This article reviews the scientific evidence on the relationship between periodontitis and neurological disease, and particularly cerebrovascular disease and dementia. We also issue a series of recommendations regarding the prevention and management of periodontitis and these neurological diseases at dental clinics and neurology units.
    Development: In response to a series of questions proposed by the SEPA-SEN working group, a literature search was performed, with no restrictions on study design, to identify the most relevant articles on the association between periodontitis and cerebrovascular disease and dementia from the perspectives of epidemiology, treatment, and the biological mechanisms involved in these associations.
    Conclusions: Periodontitis increases the risk of ischaemic stroke and Alzheimer dementia. Recurrent bacterial infections and increased low-grade systemic inflammation seem to be possible biological mechanisms underlying this association. Limited evidence suggests that various oral health interventions can reduce the future risk of cerebrovascular disease and dementia.
    MeSH term(s) Humans ; Brain Ischemia ; Stroke/epidemiology ; Stroke/etiology ; Stroke/prevention & control ; Cerebrovascular Disorders/epidemiology ; Alzheimer Disease/epidemiology ; Periodontitis/complications ; Periodontitis/epidemiology ; Periodontitis/therapy ; Neurology
    Language English
    Publishing date 2024-01-13
    Publishing country Spain
    Document type Review ; Practice Guideline
    ZDB-ID 2654369-2
    ISSN 2173-5808 ; 2173-5808
    ISSN (online) 2173-5808
    ISSN 2173-5808
    DOI 10.1016/j.nrleng.2024.01.002
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  3. Article ; Online: Spanish mental health residents' perspectives about residency education on the genetics of psychiatric disorders: A cross-sectional survey.

    Saura, Paola / García-Virumbrales, Juan / Carrasco, Juan Pablo / Pérez-Carasol, Miguel / Colomer, Lluc / Camacho-Rubio, Javier / Zorilla, Iñaki / Vilella, Elisabet

    Clinical genetics

    2023  Volume 104, Issue 4, Page(s) 427–433

    Abstract: Despite compelling evidence that some patients with a psychiatric diagnosis could benefit from genetic assessment, genetic testing for psychiatric patients is underutilized. Few studies have reported psychiatric genetics training for mental health ... ...

    Abstract Despite compelling evidence that some patients with a psychiatric diagnosis could benefit from genetic assessment, genetic testing for psychiatric patients is underutilized. Few studies have reported psychiatric genetics training for mental health specialists, and such research is especially lacking in Spain. We aimed to gather the opinions of Spanish mental health residents, including resident intern nurses (RINs), doctors (RIDs) and psychologists (RIPs). A short survey was prepared by an expert team and distributed to all mental health residency centers in Spain during the first semester of 2021. Of the 2028 residents, 18% responded. Participants were mainly females (71%), in their first year of residency (37%) and within the 27-31-year age range. While participants received little theoretical (13.4%) and practical (4.6%) training on average, RIDs had the most affirmative responses. Notably, RINs and RIDs were interested in genetics during residency (>40%) and strongly believed (85.0%) that genetics training using both theoretical and practical methodologies should be incorporated into residency training. However, RIPs were less interested (20%), and only 60% believed that genetics training should be incorporated. Spanish mental health residents, although interested in genetics in psychiatry, receive little training on this topic. They strongly believe that genetics training using theoretical and practical methodologies should be incorporated.
    MeSH term(s) Female ; Humans ; Male ; Internship and Residency ; Cross-Sectional Studies ; Mental Health ; Mental Disorders/genetics ; Surveys and Questionnaires
    Language English
    Publishing date 2023-06-17
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 221209-2
    ISSN 1399-0004 ; 0009-9163
    ISSN (online) 1399-0004
    ISSN 0009-9163
    DOI 10.1111/cge.14393
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    Zs.A 413: Show issues Location:
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  4. Article ; Online: The association between metabolic syndrome and periodontitis in Spain: Results from the WORALTH (Workers' ORAL healTH) Study.

    Montero, Eduardo / Molina, Ana / Carasol, Miguel / Fernández-Meseguer, Ana / Calvo-Bonacho, Eva / Teresa García-Margallo, María / Sanz, Mariano / Herrera, David

    Journal of clinical periodontology

    2020  Volume 48, Issue 1, Page(s) 37–49

    Abstract: Introduction: Evidence of an association between periodontitis and MetS (metabolic syndrome) remains controversial. The objective of this study is to evaluate the association between periodontitis and MetS in a cross-sectional population survey.: ... ...

    Abstract Introduction: Evidence of an association between periodontitis and MetS (metabolic syndrome) remains controversial. The objective of this study is to evaluate the association between periodontitis and MetS in a cross-sectional population survey.
    Material and methods: WORALTH (Workers' ORAL healTH) Study is a cross-sectional survey, conducted on a representative sample of the Spanish employed population, including 5154 participants. An oral examination following the World Health Organization (WHO) criteria evaluated the periodontal status using the Community Periodontal Index (CPI) and Clinical Attachment Levels (CAL). Logistic regression analysis with adjustment for potential confounders was used to evaluate the association between periodontitis and MetS, and its individual components.
    Results: Participants presenting a CPI = 4 were more likely to have MetS than subjects with CPI < 4 [odds ratio, OR = 1.41; 95% confidence interval (CI) 1.10-1.81; p < 0.001]. High blood pressure was the component with stronger association with periodontal status (OR = 1.94 for CAL ≥6 mm; 95% CI 1.49-2.53; p < 0.001). After stratifying for sex, the association was higher in women (OR = 2.20 for CPI = 4; 95% CI 1.31-3.62; p < 0.001). Non-metabolically healthy subjects, obese or not, presented a worse periodontal condition.
    Conclusion: Severe periodontitis (CPI = 4) was associated with MetS in a representative sample of the Spanish employed population. This association seems to be independent of body mass index and other potential confounders.
    MeSH term(s) Cross-Sectional Studies ; Female ; Humans ; Metabolic Syndrome/complications ; Metabolic Syndrome/epidemiology ; Oral Health ; Periodontitis/complications ; Periodontitis/epidemiology ; Spain/epidemiology
    Language English
    Publishing date 2020-11-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 188647-2
    ISSN 1600-051X ; 0303-6979
    ISSN (online) 1600-051X
    ISSN 0303-6979
    DOI 10.1111/jcpe.13391
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    Zs.A 1003: Show issues Location:
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  5. Article ; Online: Prediabetes and diabetes prevalence in the Workers' Oral Health Study.

    Montero, Eduardo / Carasol, Miguel / Fernández-Meseguer, Ana / Calvo-Bonacho, Eva / García-Margallo, María Teresa / Sanz, Mariano / Herrera, David

    Clinical oral investigations

    2019  Volume 23, Issue 12, Page(s) 4233–4241

    Abstract: Objective: To examine the association between periodontitis, diabetes, and prediabetes, assessed by fasting plasma glucose (FPG).: Materials and methods: Workers' Oral Health Study is a cross-sectional survey conducted on a representative sample of ... ...

    Abstract Objective: To examine the association between periodontitis, diabetes, and prediabetes, assessed by fasting plasma glucose (FPG).
    Materials and methods: Workers' Oral Health Study is a cross-sectional survey conducted on a representative sample of the Spanish employed population including 5154 participants (59.5% men, aged 16-65). Examination of periodontal status assessed Community Periodontal Index (CPI) and clinical attachment levels (CAL). Biochemical determinations included fasting plasma glucose (FPG), triglycerides, and total cholesterol. Logistic regression analysis with adjustment for potential confounders was used to evaluate the association between periodontitis and abnormal glucose regulation.
    Results: Ninety-five participants (2.2%) of the study population had diabetes, while 373 (8.8%) presented prediabetes. Prediabetes was not associated with CPI or CAL in fully adjusted multivariate logistic regressions models. Diabetes was significantly associated with subjects having a CPI 4 after adjustment for potential confounders (odds ratio OR = 1.9, 95% confidence interval (CI) 1.1-3.1). This association was stronger in subjects < 45 years (OR = 4.0, 95% CI 1.2-12.7).
    Conclusion: Periodontitis was associated with diabetes mellitus, but not with prediabetes, in a representative sample of the Spanish employed population. The association was stronger for younger subjects, which emphasizes the need for early detection of diabetes in younger patients affected by periodontitis, particularly because periodontal therapy may help to improve glycemic control.
    Clinical relevance: Periodontitis is associated with diabetes mellitus, having at the same time a negative effect on glycemic control. It is important to develop proper early diagnosis strategies for both conditions, particularly in young male adults.
    MeSH term(s) Adolescent ; Adult ; Aged ; Blood Glucose ; Cross-Sectional Studies ; Dental Health Surveys ; Diabetes Mellitus/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Oral Health ; Periodontitis/epidemiology ; Prediabetic State/epidemiology ; Prevalence ; Spain/epidemiology ; Young Adult
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2019-03-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1364490-7
    ISSN 1436-3771 ; 1432-6981
    ISSN (online) 1436-3771
    ISSN 1432-6981
    DOI 10.1007/s00784-019-02875-3
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    Zs.A 4788: Show issues Location:
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  6. Article ; Online: Association between caries and periodontal diseases in a sample of employed adults in Spain: a cross-sectional study.

    Martínez, María / Montero, Eduardo / Carasol, Miguel / LLodrá, Juan Carlos / Sanz, Mariano / Herrera, David / Calvo-Bonacho, Eva / Fernández-Meseguer, Ana / Figuero, Elena

    Clinical oral investigations

    2021  Volume 25, Issue 6, Page(s) 3957–3966

    Abstract: Objectives: To study whether there is an association between caries and periodontitis in a representative sample from employed Spanish adults.: Materials and methods: This cross-sectional study is part of a wide epidemiological survey (WORALTH, ... ...

    Abstract Objectives: To study whether there is an association between caries and periodontitis in a representative sample from employed Spanish adults.
    Materials and methods: This cross-sectional study is part of a wide epidemiological survey (WORALTH, Workers' ORAL healTH). Oral examination was carried out in 5130 dentate subjects. Periodontal status was assessed by clinical attachment level (CAL) and Community Periodontal Index (CPI) in index teeth. For caries, all teeth were classified as healthy, decayed (D), filled (F), or missed (M), and DMFT index and prevalence of cavitated caries were calculated. ANOVA, Chi-square tests, and regression models were performed.
    Results: DMFT increased with CAL values, being 7.8, 9.6, and 10.5 for CAL 0-3 mm, 4-5 mm, and ≥ 6 mm, respectively. After adjustment for confounders, subjects with CPI ≥ 3 showed an odds ratio of 1.6 (95% confidence interval (CI) [1.3; 1.8]; p < 0.001) for presenting cavitated caries, and patients with CAL ≥ 6 mm had 0.8 higher mean DMFT (95% CI [0.2; 1.5]; p = 0.015), and 0.3 higher mean DFR (95% CI [0.2; 0.5]; p < 0.001) than those with CAL < 6 mm.
    Conclusions: The presence of CAL ≥ 6 m mm was associated with an increased DMFT and DFR, and the presence of CPI ≥ 3 was associated with a higher prevalence of cavitated caries in this representative sample.
    Clinical relevance: There is a tendency to present higher prevalence of dental caries among patients with periodontitis. Therefore, common preventive measures in dentistry, such as oral hygiene practices, should ideally include actions aimed to prevent at the same time dental caries and periodontitis.
    MeSH term(s) Adult ; Cross-Sectional Studies ; DMF Index ; Dental Caries/epidemiology ; Dental Caries Susceptibility ; Humans ; Oral Health ; Periodontal Diseases/epidemiology ; Prevalence ; Spain/epidemiology
    Language English
    Publishing date 2021-01-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1364490-7
    ISSN 1436-3771 ; 1432-6981
    ISSN (online) 1436-3771
    ISSN 1432-6981
    DOI 10.1007/s00784-020-03726-2
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    Zs.A 4788: Show issues Location:
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  7. Article ; Online: Nonsurgical treatment of periodontitis.

    Sanz, Ignacio / Alonso, Bettina / Carasol, Miguel / Herrera, David / Sanz, Mariano

    The journal of evidence-based dental practice

    2012  Volume 12, Issue 3 Suppl, Page(s) 76–86

    Abstract: Context: Scaling and root planing (SRP) is the gold standard treatment for most patients with chronic periodontitis. Nevertheless, in the last years, different therapeutic strategies have been proposed to improve the results of SRP and hence to avoid ... ...

    Abstract Context: Scaling and root planing (SRP) is the gold standard treatment for most patients with chronic periodontitis. Nevertheless, in the last years, different therapeutic strategies have been proposed to improve the results of SRP and hence to avoid the need of periodontal surgical interventions in some patients with advanced periodontitis. They are based on modifications of standard therapies (such as enhancement of instrument tip designs), on development of new technologies (such as lasers), or development of alternative treatment protocols (eg, full-mouth disinfection). The purpose of this review is, therefore, to update the scientific evidence based on randomized clinical trials (RCT) evaluating these advanced nonsurgical therapies that have been published between January 2010 and March 2012.
    Evidence acquisition: RCTs published between January 2010 and March 2012 have been selected. Previous systematic reviews were used as a start point. Three distinct aspects were evaluated independently: the modification of conventional instruments, the advent of new technologies, and the development of new treatment protocols.
    Evidence synthesis: Twenty-two publications were selected: 4 were related to modifications of standard therapies (new tip designs and local anesthetics), 14 to new technologies (new ultrasonic devices, air abrasive systems, endoscope and lasers), and 4 to new treatment protocols.
    Conclusions: These technological advances and the development of new protocols may improve patient-related outcomes and cost-effectiveness, although they have not shown significant differences in efficacy when compared with conventional SRP.
    MeSH term(s) Anti-Infective Agents, Local ; Clinical Protocols ; Dental Instruments ; Dental Scaling/instrumentation ; Dental Scaling/methods ; Humans ; Periodontal Index ; Periodontitis/therapy ; Root Planing/instrumentation ; Root Planing/methods ; Treatment Outcome
    Chemical Substances Anti-Infective Agents, Local
    Language English
    Publishing date 2012-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2056058-8
    ISSN 1532-3390 ; 1532-3382
    ISSN (online) 1532-3390
    ISSN 1532-3382
    DOI 10.1016/S1532-3382(12)70019-2
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    Zs.A 5561: Show issues Location:
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  8. Article ; Online: Periodontal conditions among employed adults in Spain.

    Carasol, Miguel / Llodra, Juan Carlos / Fernández-Meseguer, Ana / Bravo, Manuel / García-Margallo, María Teresa / Calvo-Bonacho, Eva / Sanz, Mariano / Herrera, David

    Journal of clinical periodontology

    2016  Volume 43, Issue 7, Page(s) 548–556

    Abstract: Aim: To assess the prevalence and severity of periodontal conditions among a representative sample of employed adults in Spain.: Material and methods: A national cross-sectional study was conducted during 2008-2011. Periodontal status of 5130 workers, ...

    Abstract Aim: To assess the prevalence and severity of periodontal conditions among a representative sample of employed adults in Spain.
    Material and methods: A national cross-sectional study was conducted during 2008-2011. Periodontal status of 5130 workers, stratified by gender, age and occupation, was assessed based on Community Periodontal Index (CPI) and Clinical Attachment Level (CAL), following the WHO criteria.
    Results: The percentage of subjects with periodontal pockets (CPI codes 3-4) was 38.4%, [95% Confidence Interval (CI): 36.4-40.5] increasing significantly in subjects ≥45 years; 13.7% (95% CI: 12.8-14.7) of workers showed CAL 4-5 mm, while 7.7% (95% CI: 7.0-8.5) showed CAL ≥6 mm, again increasing significantly in the population ≥45 years. Prevalence of worse periodontal conditions was significantly higher in male workers, in subjects with primary school education and lower income, and in smokers and former smokers. The periodontal condition in young adults (35-44 years) was worse in comparison with those previously reported in Spanish national surveys.
    Conclusion: Prevalence of destructive periodontal diseases was age-, gender-, education-, income- and tobacco smoking-related. Young adults showed worse periodontal conditions than has been previously reported in national surveys in Spain. It is suggested to include oral evaluation and preventive strategies in work-related medical check-ups.
    MeSH term(s) Adult ; Cross-Sectional Studies ; Female ; Humans ; Male ; Periodontal Diseases ; Periodontal Index ; Prevalence ; Spain
    Language English
    Publishing date 2016-05-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 188647-2
    ISSN 1600-051X ; 0303-6979
    ISSN (online) 1600-051X
    ISSN 0303-6979
    DOI 10.1111/jcpe.12558
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  9. Article: Algunas consideraciones a las indicaciones y técnica de la intubación orotraqueal por vía submental.

    Hernández Montero, S / Hernández Montero, E / Viu, E / Moros Peña, F M / Carasol, M

    Revista espanola de anestesiologia y reanimacion

    2004  Volume 51, Issue 10, Page(s) 615–6; author reply 616

    Title translation On indications and techniques for submental orotracheal intubation.
    MeSH term(s) Chin ; Humans ; Intubation, Intratracheal/methods
    Language Spanish
    Publishing date 2004-12
    Publishing country Spain
    Document type Comment ; Letter
    ZDB-ID 604162-0
    ISSN 2340-3284 ; 0034-9356 ; 1131-4044
    ISSN (online) 2340-3284
    ISSN 0034-9356 ; 1131-4044
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    Zs.A 445: Show issues Location:
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  10. Article: Mandibular cementifying fibroma in relation to a large periodontal bone defect. Report of a case.

    Alández, J / Herrera, J I / Sanz, M / Carasol, M

    Journal of periodontology

    1995  Volume 66, Issue 4, Page(s) 291–294

    Abstract: A cementifying fibroma associated with a large intraosseous periodontal defect is reported. This tumor was located in the lingual aspect of the first lower left molar. Therapy consisted on flap surgery, tumor excision, and placement of a bone autograft ... ...

    Abstract A cementifying fibroma associated with a large intraosseous periodontal defect is reported. This tumor was located in the lingual aspect of the first lower left molar. Therapy consisted on flap surgery, tumor excision, and placement of a bone autograft in order to fill the residual bone defect. Six months after the treatment, clinical and radiographic signs of periodontal regeneration were evidenced.
    MeSH term(s) Adult ; Bone Transplantation ; Female ; Humans ; Mandibular Neoplasms/complications ; Mandibular Neoplasms/surgery ; Odontogenic Tumors/complications ; Odontogenic Tumors/surgery ; Periodontal Pocket/etiology ; Periodontal Pocket/surgery
    Language English
    Publishing date 1995-04
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 390921-9
    ISSN 1943-3670 ; 0022-3492 ; 1049-8885 ; 0095-960X
    ISSN (online) 1943-3670
    ISSN 0022-3492 ; 1049-8885 ; 0095-960X
    DOI 10.1902/jop.1995.66.4.291
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