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  1. Article ; Online: Diaphragmatic dysfunction associated with invasive mechanical ventilation in critically ill adult patients

    Tocalini, Pablo / Vicente, Antonela / Carballo, Juan Manuel / Garegnani, Luis Ignacio

    Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina)

    2021  Volume 78, Issue 2, Page(s) 197–206

    Abstract: Invasive mechanical ventilation (VMI) is a life support therapy that is not free of complications, such as ventilator induced diaphragmatic dysfunction, which is characterized by atrophy and weakness of the muscle. Interest in this pathology seems to be ... ...

    Title translation [Disfunción diafragmática asociada a la ventilación mecánica invasiva en pacientes adultos críticamente enfermos]
    Abstract Invasive mechanical ventilation (VMI) is a life support therapy that is not free of complications, such as ventilator induced diaphragmatic dysfunction, which is characterized by atrophy and weakness of the muscle. Interest in this pathology seems to be based on the association found with negative clinical results. The prevalence ranges between 29 and 80%, probably due to the variability between the different diagnostic methods and the time of evaluation. The gold standard continues to be the transdiaphragmatic negative pressure generated by the bilateral stimulation of the phrenic nerves, although due to the lack of practicality, diaphragmatic ultrasound began to be used. Although it has several modalities, not all of them have correlation analysis with the gold standard. Another problem arises when analyzing the independent association between pathology and VMI, since confusing factors are not easy to isolate.
    MeSH term(s) Adult ; Critical Illness ; Humans ; Respiration, Artificial ; Retrospective Studies
    Language Spanish
    Publishing date 2021-06-28
    Publishing country Argentina
    Document type Journal Article
    ZDB-ID 390127-0
    ISSN 1853-0605 ; 0014-6722 ; 0301-7281
    ISSN (online) 1853-0605
    ISSN 0014-6722 ; 0301-7281
    DOI 10.31053/1853.0605.v78.n2.28458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Impact of implementing a protocol of respiratory care measures and optimization of mechanical ventilation in potential lung donors.

    Bezzi, Marco Guillermo / Brovia, Carla Candela / Carballo, Juan Manuel / Elías, Maia Inés / Moreno, Agustina Belén / Ruiz, Vanesa Romina / Cordiviola, Fernanda / Barbieri, David / Fariña, Adriana / Borello, Silvina

    Revista Brasileira de terapia intensiva

    2021  Volume 32, Issue 4, Page(s) 571–577

    Abstract: Objective: To describe the results from the implementation of a respiratory care and mechanical ventilation protocol on potential lung donors who met the conditions for procurement. The secondary objective is to compare the results with historical data.! ...

    Title translation Impacto de la implementación de medidas de cuidados respiratorios y optimización de la ventilación mecánica en potenciales donantes de pulmón.
    Abstract Objective: To describe the results from the implementation of a respiratory care and mechanical ventilation protocol on potential lung donors who met the conditions for procurement. The secondary objective is to compare the results with historical data.
    Methods: This was a retrospective, observational study. It included potential donors suitable for procurement of organs who had brain death and were hospitalized in critical care units of the Autonomous City of Buenos Aires from April 2017 to March 2018. Main variables: number of potential lung donors that reached the objective of procurement, rate of lungs procured, and rate of implanted lungs. Values of p < 0.05 were considered significant.
    Results: Thirty potential lung donors were included, and 23 (88.5%; 95%CI 69.8 - 97.6) met the oxygenation objective. Twenty potential lung donors donated organs, of whom eight donated lungs, with which four double lung transplants and eight single lung transplants were performed. Seven of 12 lungs were procured and implanted in the preprotocol period, while all 12 were under the protocol (p = 0.38). The implantation rate was 58.3% (7/12) in the historical control period and 100% (12/12) (p = 0.04) in the study period.
    MeSH term(s) Brain Death ; Humans ; Lung ; Lung Transplantation ; Respiration, Artificial ; Retrospective Studies ; Tissue Donors ; Tissue and Organ Procurement
    Language English
    Publishing date 2021-01-20
    Publishing country Brazil
    Document type Journal Article ; Observational Study
    ZDB-ID 2732162-9
    ISSN 1982-4335 ; 1982-4335
    ISSN (online) 1982-4335
    ISSN 1982-4335
    DOI 10.5935/0103-507X.20200095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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