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Article ; Online: Patients Living with Arterial Hypertension in Mexico: First Insights of The Mexican Registry of Arterial Hypertension (RIHTA Study).

Palomo-Piñón, Silvia / Antonio-Villa, Neftali Eduardo / García-Cortés, Luis Rey / Moreno-Noguez, Moises / Alcocer, Luis / Álvarez-López, Humberto / Cardona-Muñoz, Ernesto G / Chávez-Mendoza, Adolfo / Díaz-Díaz, Enrique / Enciso-Muñoz, José Manuel / Galván-Oseguera, Héctor / Rosas-Peralta, Martin

American journal of hypertension

2024

Abstract: Background: Arterial hypertension is a significant cause of morbidity and mortality in Mexico. However, there is limited data available to understand blood pressure management and cardiometabolic profiles.: Aims: To assess the prevalence of ... ...

Abstract	Background: Arterial hypertension is a significant cause of morbidity and mortality in Mexico. However, there is limited data available to understand blood pressure management and cardiometabolic profiles. Aims: To assess the prevalence of controlled and uncontrolled blood pressure, as well as the prevalence of cardiometabolic risk factors among patients from the Mexican Registry of Arterial Hypertension (RIHTA). Methods: We conducted a cross-sectional analysis of participants living with arterial hypertension registered on RIHTA between December 2021 and April 2023. We used both the 2017 ACC/AHA and 2018 ESC/ESH thresholds to define controlled and uncontrolled arterial hypertension. We considered eleven cardiometabolic risk factors, which include overweight, obesity, central obesity, insulin resistance, diabetes, hypercholesterolemia, hypertriglyceridemia, low-HDL-C, high-LDL-C, low-eGFR, and high CVD risk. Results: In a sample of 5,590 participants (female: 61%, n=3,393; median age: 64 [IQR: 56-72] years), the prevalence of uncontrolled hypertension varied significantly, depending on the definition (2017 ACC/AHA: 59.9%, 95% CI: 58.6-61.2 and 2018 ESC/ESH: 20.1%, 95% CI: 19.0-21.2). In the sample, 40.43% exhibited at least 5-6 risk factors, and 32.4% had 3-4 risk factors, chiefly abdominal obesity (83.4%, 95% CI: 82.4-84.4), high-LDL-C (59.6%, 95% CI: 58.3-60.9), high-CVD risk (57.9%, 95% CI: 56.6-59.2), high triglycerides (56.2%, 95% CI: 54.9-57.5), and low-HDL-C (42.2%, 95% CI: 40.9-43.5). Conclusion: There is a high prevalence of uncontrolled hypertension interlinked with a high burden of cardiometabolic comorbidities in Mexican adults living with arterial hypertension, underscoring the urgent need for targeted interventions and better healthcare policies to reduce the burden of the disease in our country.
Language	English
Publishing date	2024-03-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	639383-4
ISSN	1941-7225 ; 1879-1905 ; 0895-7061
ISSN (online)	1941-7225 ; 1879-1905
ISSN	0895-7061
DOI	10.1093/ajh/hpae024
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Article ; Online: Effects of Renin-Angiotensin System Inhibitors on Atrial Mechanics Parameters in Patients with Metabolic Syndrome.

Peraza-Zaldivar, Juan A / Ponce-Guarneros, Juan M / Cardona-Muñoz, Ernesto G / Esparza-Guerrero, Yussef / Saldaña-Cruz, Ana M / González-Vazquez, Sergio A / Gonzalez-Lopez, Laura / Gamez-Nava, Jorge I / Rodriguez-Jimenez, Norma A

Journal of cardiovascular pharmacology and therapeutics

2023 Volume 28, Page(s) 10742484231216807

Abstract: Introduction: Metabolic syndrome (MS) is associated with abnormalities in atrial mechanics, atrial remodeling, and an increased risk of heart rhythm disorders. One of the most commonly used approaches to the prevention of cardiac remodeling in arterial ... ...

Abstract	Introduction: Metabolic syndrome (MS) is associated with abnormalities in atrial mechanics, atrial remodeling, and an increased risk of heart rhythm disorders. One of the most commonly used approaches to the prevention of cardiac remodeling in arterial hypertension is the administration of renin-angiotensin system (RAS) inhibitors. Therefore, this study aimed to investigate the effects of RAS inhibitors on atrial mechanics parameters in patients with MS. Methods and materials: This longitudinal observational study included 55 patients with hypertension and MS, as defined by the ATP III criteria. The patients were evaluated at the start of antihypertensive treatment with an RAS inhibitor. The patients' clinical characteristics, chosen pharmacological treatment, and transthoracic echocardiography findings were recorded at baseline and 6 months thereafter. A student's dependent sample Results: Patients with MS had higher peak atrial longitudinal strain (PALS) values at 6 months than at baseline. Meanwhile, systolic strain and peak late strain rates were lower at follow-up than at baseline. The different antihypertensive treatments had comparable effects on the PALS changes during the follow-up period. Higher high-density lipoprotein levels at baseline were correlated with changes in PALS. Conclusion: The administration of RAS inhibitors improved atrial mechanics parameters in the early stages of antihypertensive management in MS.
MeSH term(s)	Humans ; Antihypertensive Agents/therapeutic use ; Antihypertensive Agents/pharmacology ; Atrial Fibrillation ; Renin-Angiotensin System ; Metabolic Syndrome/diagnosis ; Metabolic Syndrome/drug therapy ; Metabolic Syndrome/complications ; Heart Atria ; Hypertension/diagnosis ; Hypertension/drug therapy ; Enzyme Inhibitors/pharmacology
Chemical Substances	Antihypertensive Agents ; Enzyme Inhibitors
Language	English
Publishing date	2023-11-28
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	1329372-2
ISSN	1940-4034 ; 1074-2484
ISSN (online)	1940-4034
ISSN	1074-2484
DOI	10.1177/10742484231216807
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Zs.A 4895: Show issues

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Article: A cross-sectional study on the prevalence of cardiovascular disease in elderly patients with long-term type 2 diabetes mellitus mainly attended in private clinics in Mexico. The CAPTURE study.

Arenas-León, José L / Morales-Villegas, Enrique C / Cardona-Muñoz, Ernesto G / Alcocer-Gamba, Marco A / Ramirez-Contreras, Juan P / Contreras-Sandoval, Aleida Y / González-Galvez, Guillermo

Diabetology & metabolic syndrome

2023 Volume 15, Issue 1, Page(s) 258

Abstract: Background: To estimate the contemporary prevalence of established cardiovascular disease (CVD) in adults with type 2 diabetes (T2D) in Mexico.: Methods: CAPTURE was a multinational, non-interventional, cross-sectional study across 13 countries from ... ...

Abstract	Background: To estimate the contemporary prevalence of established cardiovascular disease (CVD) in adults with type 2 diabetes (T2D) in Mexico. Methods: CAPTURE was a multinational, non-interventional, cross-sectional study across 13 countries from five continents. Standardized demographic and clinical data were collected from adults with T2D attending a single routine healthcare visit in primary or specialized care between December 2018 and September 2019. Data from Mexico are analyzed in this study. Results: Of the 9,823 patients included in the CAPTURE study, 820 (8.3%) participants were from Mexico, mainly attended in private centers (29.3% in 6 specialized diabetes treatment centers and 70.7% in 26 primary care centers). The median age was 63.0 years, 52.6% were women, the duration of diabetes was 11.8 years and the average HbA1c 7.5%. The weighted prevalence [95% CI] of CVD and atherosclerotic CVD was 36.9% [34.1-39.6] and 29.5% [26.7-32.3], respectively. Additionally, the prevalence of coronary heart disease, heart failure, peripheral arterial disease and cerebrovascular disease was 23.1% [20.6-25-7], 8.4% [6.8-10.0], 5.0% [3.5-6.5] and 3.9% [2.6-5.2], respectively. Glucose lowering drugs were used in 88.5% of patients, being metformin the most commonly drug used (79.4%), followed by sulfonylureas (26.3%). SGLT-2 inhibitors and GLP1 receptor agonists were used in 15.5% and 3.9%, respectively. Conclusions: In Mexico, nearly four out of ten patients with T2D mainly attended in private centers have CVD, particularly atherosclerotic CVD. Most patients were not taking glucose lowering drugs with proven CV benefit.
Language	English
Publishing date	2023-12-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2518786-7
ISSN	1758-5996
ISSN	1758-5996
DOI	10.1186/s13098-023-01231-6
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Article ; Online: Tadalafil Improves Haemodynamics and Arterial Stiffness but Not Flow- Mediated Dilation in Grade 1 Obesity. A Single-dose, Placebo-controlled Clinical Trial.

Larios-Cárdenas, Mariana / González-Radillo, Oscar I / Trujillo-Quirós, Jhonatan / Cardona-Müller, David / Barocio-Pantoja, Marycruz / Cardona-Muñoz, Ernesto G / Grover-Páez, Fernando

Current vascular pharmacology

2022 Volume 20, Issue 6, Page(s) 527–533

Abstract: Objective: Obesity, a major health issue worldwide, is associated with increased cardiovascular risk, endothelial dysfunction, and arterial stiffness. Tadalafil has been demonstrated to improve vascular parameters.: Aim: To evaluate the effect of a ... ...

Abstract	Objective: Obesity, a major health issue worldwide, is associated with increased cardiovascular risk, endothelial dysfunction, and arterial stiffness. Tadalafil has been demonstrated to improve vascular parameters. Aim: To evaluate the effect of a single 20 mg dose of tadalafil on flow-mediated dilation and hemodynamic and arterial stiffness markers. Methods: A randomized, double-blind, placebo-controlled study was conducted on 80 participants (41 assigned to placebo and 39 to tadalafil) with grade 1 obesity, to evaluate the acute effect of a single dose of 20 mg of tadalafil on flow-mediated dilation and hemodynamic and arterial stiffness markers. Results: Tadalafil did not modify flow-mediated dilation. However, it significantly lowered systolic blood pressure (SBP) (130.6±17.1 vs. 125.0±12.7 mmHg, p=0.011), diastolic blood pressure (82.7±18.2 vs. 76.5±11.8 mmHg, p≤0.001), central systolic blood pressure (116.33±19.16 vs. 109.90±15.05 mmHg, p=0.001), the augmentation index (69.1±17.1 vs. 65.7±14.4, p=0.012), and brachial-ankle pulse wave velocity (1229.7±218.4 vs. 1164.0±181.7, p=0.001). Conclusion: A single dose of tadalafil did not modify flow-mediated dilation in patients with grade 1 obesity but improved blood pressure and brachial-ankle pulse wave velocity.
MeSH term(s)	Humans ; Vascular Stiffness ; Pulse Wave Analysis ; Tadalafil/adverse effects ; Ankle Brachial Index ; Dilatation ; Blood Pressure ; Hemodynamics ; Obesity/diagnosis ; Obesity/drug therapy ; Double-Blind Method
Chemical Substances	Tadalafil (742SXX0ICT)
Language	English
Publishing date	2022-08-31
Publishing country	United Arab Emirates
Document type	Randomized Controlled Trial ; Clinical Trial
ZDB-ID	2192362-0
ISSN	1875-6212 ; 1570-1611
ISSN (online)	1875-6212
ISSN	1570-1611
DOI	10.2174/1570161120666220827154417
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Zs.A 6282: Show issues

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Article: Risk Factors of Muscle Wasting in Women with Rheumatoid Arthritis: Relevance of the Persistent Failure of Conventional Combination Therapy.

Gomez-Ramirez, Eli E / Ramirez-Villafaña, Melissa / Gamez-Nava, Jorge I / Cons-Molina, Fidencio / Rodriguez Jimenez, Norma A / Saldaña-Cruz, Ana M / Cardona-Muñoz, Ernesto G / Totsuka-Sutto, Sylvia E / Ponce-Guarneros, Juan M / Trujillo, Xochitl / Huerta, Miguel / Cruz-Jentoft, Alfonso J / Gonzalez-Lopez, Laura

Healthcare (Basel, Switzerland)

2022 Volume 10, Issue 10

Abstract: Background: Muscle wasting, also known as myopenia, is frequent in rheumatoid arthritis (RA). To date, it is still unknown if the failure of pharmacologic therapies increases the risk of myopenia in RA. Objective: To identify if treatment failure with ... ...

Abstract	Background: Muscle wasting, also known as myopenia, is frequent in rheumatoid arthritis (RA). To date, it is still unknown if the failure of pharmacologic therapies increases the risk of myopenia in RA. Objective: To identify if treatment failure with conventional synthetic DMARDs (csDMARDs) constitutes an independent risk factor of muscle wasting in women with RA. Methods: This was a cross-sectional study. We included 277 women with RA. Assessments in RA patients included: clinical, epidemiological, and therapeutic variables. The skeletal muscle index (SMI) was estimated by DXA, and myopenia was diagnosed if they had an SMI < 5.45 kg/m2. Multivariable logistic regression models identified risk factors of myopenia. Results: Muscle wasting was observed in 28.2% of patients with RA. The risk factors of myopenia in RA were menopausal (OR: 4.45, 95% CI: 1.86 to 10.64) and failure of combined therapy with csDMARDs (OR: 2.42, 95% CI: 1.15 to 5.07). The increased body mass index was protective (OR:0.81, 95% CI: 0.75 to 0.87). Conclusions: Around one of four patients with RA presented muscle wasting. Muscle wasting is related to treatment failure of combined csDMARDs; other factors influencing the presence of muscle wasting is being postmenopausal, whereas, the body mass index was a protective factor.
Language	English
Publishing date	2022-10-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare10102004
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Article: Real-World Evidence Evaluation on the Lipid Profile, Therapeutic Goals, and Safety of the Fixed-Dose Combination of Rosuvastatin/Ezetimibe (Trezete®) in Dyslipidemia Patients.

Rodríguez-Saldaña, Joel / Padilla-Padilla, Francisco / Cardona-Muñoz, Ernesto G / Romero-Antonio, Yulia / Arguedas-Núñez, María Marcela / Sander-Padilla, José G / Martínez-Muñoz, Alberto / Lugo-Sánchez, Laura A / Rodríguez-Vazquez, Ileana C / González-Canudas, Jorge

Cardiology research and practice

2022 Volume 2022, Page(s) 9464733

Abstract: Introduction: Cardiovascular diseases are the leading cause of death worldwide. The combination of statins and cholesterol-absorption inhibitors promotes the decrease in risk factors, such as high concentrations of LDL (low-density lipoproteins). The ... ...

Abstract	Introduction: Cardiovascular diseases are the leading cause of death worldwide. The combination of statins and cholesterol-absorption inhibitors promotes the decrease in risk factors, such as high concentrations of LDL (low-density lipoproteins). The aim of the study was to evaluate changes in the lipid profile and the effect on therapeutic goals, as well as the safety of dyslipidemia patients treated with Rosuvastatin/Ezetimibe (Trezete®). Materials and methods: A real-world evidence study was conducted with retrospective data collection through a review of clinical records from dyslipidemia patients treated with Trezete® in routine medical practice. Clinical records included results of biochemical markers before treatment and at least one follow up between weeks 8 and 16. Results: The study included 103 patients' clinical records (55.4% men) with a mean age of 56.0 ± 13.0 years. More than 57% of the patients had mixed dyslipidemia and a median disease progression of 3.1 (IQR, 1.5; 9.1) years. Regarding LDL concentrations, 72.8% of the patients achieved therapeutic goals according to cardiovascular risk (CVR), which was statistically significant. Similarly, 94.1% achieved goals for total cholesterol (<200 mg/dL) and 56.0% for triglycerides (<150 mg/dL), a Conclusion: Trezete® shows an important clinical impact on CVR-related target markers during the treatment of dyslipidemia patients. It is relevant to mention that a significant percentage of patients achieved therapeutic goals during the first months of treatment. Fixed-dose combination therapy has shown to be as safe as monotherapy treatment. ClinicalTrials.gov Identifier: NCT04862962.
Language	English
Publishing date	2022-09-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2506187-2
ISSN	2090-0597 ; 2090-8016
ISSN (online)	2090-0597
ISSN	2090-8016
DOI	10.1155/2022/9464733
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Article ; Online: Percentage of change and increment of the glucose level after a normal oral tolerance curve between 24 and 28 weeks of pregnancy.

Zavalza-Gómez, Ana B / Pérez-Hernández, Sandra C / Arrazola-Fregozo, Aldo G / Espinel-Bermúdez, María C / Grover-Páez, Fernando / González, Sara Pascoe / Ramos-Zavala, Maria G / Cardona-Muñoz, Ernesto G / Cardona-Müller, David / Hernández-González, Sandra O

The journal of obstetrics and gynaecology research

2022 Volume 49, Issue 3, Page(s) 846–851

Abstract: Aim: To determine the percentage of change and increment in glucose levels after a normal oral glucose tolerance test between 24 and 28 weeks of pregnancy.: Methods: We studied 3510 pregnant women who attended their obstetric delivery at a tertiary ... ...

Abstract	Aim: To determine the percentage of change and increment in glucose levels after a normal oral glucose tolerance test between 24 and 28 weeks of pregnancy. Methods: We studied 3510 pregnant women who attended their obstetric delivery at a tertiary care hospital in Guadalajara, Mexico in 2018, according to characteristics and risk 1647 (47%) patients were screened for diabetes diagnosis using the oral glucose tolerance test, 501 patients reported normal values between their 24th and 28th week of pregnancy, only 400 patients had their fasting glucose level measured on the same day of their obstetric delivery, to be compared. Results: Average age was 30 years, with an average of 25.3 weeks of pregnancy. The fasting serum glucose levels taken after 28 weeks of pregnancy and before the obstetrical delivery showed an increase of 1.1 mmol/L in women who develop gestational diabetes mellitus, in contrast to women who did not develop gestational diabetes mellitus after 28 weeks their blood glucose only increased on average 0.4 mmol/L. The incidence of gestational diabetes mellitus in the study population during 2018 was 32.7%. Patients who developed gestational diabetes mellitus after a normal oral glucose tolerance test had greater body mass index before the pregnancy and newborns had a higher weight than babies born to mothers without gestational diabetes mellitus. Conclusion: Changes in glucose levels after the oral tolerance test of normal glucose require strict monitoring, in that it was demonstrated that 3% of patients developed gestational diabetes mellitus after week 28 of gestation.
MeSH term(s)	Pregnancy ; Female ; Humans ; Infant, Newborn ; Adult ; Diabetes, Gestational ; Blood Glucose ; Glucose Tolerance Test ; Parturition ; Mexico
Chemical Substances	Blood Glucose
Language	English
Publishing date	2022-12-08
Publishing country	Australia
Document type	Journal Article
ZDB-ID	1327307-3
ISSN	1447-0756 ; 1341-8076
ISSN (online)	1447-0756
ISSN	1341-8076
DOI	10.1111/jog.15517
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Zs.A 1810: Show issues

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Article ; Online: Effectiveness of degradable and non-degradable implants to close large septal perforations in an experimental model.

Hernández Martinez, Victor M / Garcia Benavides, Leonel / Totsuka Sutto, Sylvia E / Cardona Muñoz, Ernesto G / Campos Bayardo, Tania Isabel / Pascoe Gonzalez, Sara

Journal of plastic surgery and hand surgery

2016 Volume 50, Issue 4, Page(s) 222–226

Abstract: Background Reparation of large nasal septum perforations continues to be challenging. Bipedicled mucoperichondrial and inter-positional grafts currently show the most promising results. New implants have emerged to be used as a support membrane to carry ... ...

Abstract	Background Reparation of large nasal septum perforations continues to be challenging. Bipedicled mucoperichondrial and inter-positional grafts currently show the most promising results. New implants have emerged to be used as a support membrane to carry on the mucosal cells, taking advantage of the innate proliferative properties of the mucosal tissue. Objective To compare the effectiveness of two kinds of material; non-absorbable dimethylsiloxane (silicone elastomers) and absorbable porcine small intestinal submucosa (Surgisis), both used as an inter-positional graft without neighbouring flaps to close nasal septal perforations in an experimental model. Methods Fifteen dogs were divided into three groups. One group received Surgisis, the other sheets of dimethylsiloxane and the last group a sham group. The dogs were followed for 6 weeks. Results The initial perforation of the nasal septum showed complete mucosal closure in the dimethylsiloxane group. The Surgisis group, on the other hand, had a smaller reduction than that at the beginning (final mean area = 23.0 ± 5.4 mm(2) (p < 0.05); however, complete closure was not achieved. Sham animals showed an inconstant and slight reduction in dimension from 100 mm(2) to 70 ± 16 mm(2) of mucosa and cartilage, but closure was not achieved. A significantly higher number of capillaries were observed in the Surgisis group compared to the dimethylsiloxane group (p < 0.05) without differences in inflammation, fibrosis, or necrosis. Conclusions The non-absorbable implant; dimethylsiloxane facilitates a better closure of the nasal septum.
MeSH term(s)	Absorbable Implants ; Animals ; Collagen ; Dimethylpolysiloxanes ; Dogs ; Intestinal Mucosa ; Models, Animal ; Nasal Mucosa/anatomy & histology ; Nasal Septal Perforation/surgery ; Nasal Septum/surgery ; Prostheses and Implants ; Rhinoplasty/methods ; Swine
Chemical Substances	Dimethylpolysiloxanes ; surgisis ; Collagen (9007-34-5)
Language	English
Publishing date	2016-08
Publishing country	Sweden
Document type	Comparative Study ; Journal Article
ZDB-ID	2551921-9
ISSN	2000-6764 ; 2000-656X
ISSN (online)	2000-6764
ISSN	2000-656X
DOI	10.3109/2000656X.2016.1152973
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Article ; Online: Serum chemerin levels: A potential biomarker of joint inflammation in women with rheumatoid arthritis.

Gonzalez-Ponce, Fabiola / Gamez-Nava, Jorge I / Perez-Guerrero, Emilio E / Saldaña-Cruz, Ana M / Vazquez-Villegas, Maria L / Ponce-Guarneros, Juan M / Huerta, Miguel / Trujillo, Xochitl / Contreras-Haro, Betsabe / Rocha-Muñoz, Alberto D / Carrillo-Escalante, Maria O / Sanchez-Rodriguez, Esther N / Gomez-Ramirez, Eli E / Nava-Valdivia, Cesar A / Cardona-Muñoz, Ernesto G / Gonzalez-Lopez, Laura

PloS one

2021 Volume 16, Issue 9, Page(s) e0255854

Abstract: Background: Chemerin has a potential role in perpetuating inflammation in autoimmune diseases. Nevertheless, to date, there is no conclusive information on whether high chemerin levels increase the severity of rheumatoid arthritis (RA). Therefore, this ... ...

Abstract	Background: Chemerin has a potential role in perpetuating inflammation in autoimmune diseases. Nevertheless, to date, there is no conclusive information on whether high chemerin levels increase the severity of rheumatoid arthritis (RA). Therefore, this study evaluated whether serum chemerin is a biomarker of disease activity in RA patients. Methods: Study design: cross-sectional. The assessment included clinical and laboratory characteristics, body mass index (BMI) and fat mass. The severity of the disease activity was identified according to the DAS28-CRP index as follows: A) RA with a DAS28-CRP≤2.9 (remission/mild activity) and B) RA with a DAS28-CRP>2.9 (moderate/severe activity). Serum chemerin concentrations were measured by ELISA, and ≥103 ng/mL was considered a high level. Logistic regression analysis was applied to determine whether high chemerin levels were associated with disease activity in RA after adjusting for confounders. Multiple regression analysis was performed to identify variables associated with chemerin levels. Results: Of 210 RA patients, 89 (42%) subjects had moderate/severe disease activity and had higher serum chemerin levels than patients with low disease activity or remission (86 ± 34 vs 73± 27; p = 0.003). Serum chemerin correlated with the number of swollen joints (r = 0.15; p = 0.03), DAS28-CRP (r = 0.22; p = 0.002), and C-reactive protein levels (r = 0.14; p = 0.04), but no correlation was observed with BMI and fat mass. In the adjusted logistic regression analysis, high chemerin levels (≥103 ng/mL) were associated with an increased risk of moderate/severe disease activity (OR: 2.76, 95% CI 1.35-5.62; p = 0.005). In the multiple regression analysis, after adjusting for potential confounders, serum chemerin levels were associated with higher DAS28-CRP (p = 0.002). Conclusions: Higher chemerin levels increased the risk of moderate and severe disease activity in RA. These results support the role of chemerin as a marker of inflammation in RA. Follow-up studies will identify if maintaining low chemerin levels can be used as a therapeutic target.
MeSH term(s)	Arthritis, Rheumatoid/complications ; Biomarkers/blood ; C-Reactive Protein/analysis ; Chemokines/blood ; Cross-Sectional Studies ; Female ; Humans ; Inflammation/blood ; Inflammation/diagnosis ; Inflammation/etiology ; Knee Joint/pathology ; Middle Aged ; Prognosis ; Severity of Illness Index
Chemical Substances	Biomarkers ; Chemokines ; RARRES2 protein, human ; C-Reactive Protein (9007-41-4)
Language	English
Publishing date	2021-09-10
Publishing country	United States
Document type	Journal Article ; Observational Study
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0255854
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Article ; Online: Confiabilidad de un monitor automatizado para la medición de la presión arterial.

Cardona-Müller, David / Grover-Páez, Fernando / Guzmán-Saldivar, Víctor / Alanis-Sánchez, Guillermo A / Murguía-Soto, César / Totsuka-Sutto, Sylvia E / Quezada-Fernández, Patricia / Macías-Chumacera, Agustín / Cardona-Muñoz, Ernesto G / Ramos-Becerra, Carlos G

Revista medica de Chile

2018 Volume 146, Issue 2, Page(s) 190–195

Abstract: Background A correct blood pressure (BP) measurement is essential for the diagnosis and control of high BP.: Aim: To evaluate the agreement and repeatability of BP measurements with the OMRON HEM-7320-LA device compared to a mercury sphygmomanometer.!# ...

Title translation	Reliability of an automatic monitor for blood pressure measurement.
Abstract	Background A correct blood pressure (BP) measurement is essential for the diagnosis and control of high BP. Aim: To evaluate the agreement and repeatability of BP measurements with the OMRON HEM-7320-LA device compared to a mercury sphygmomanometer. Material and methods: A cross-sectional study comparing BP measurements made by two randomly selected trained nurses and an automatic oscillometric device. The mercurial sphygmomanometer was connected to the automated device via a "T" type connector and a dual-head stethoscope was used, allowing simultaneous measurements. The results were analyzed with one-factor analysis of variance, Bland-Altman's test, repeatability coefficient (RC), and intra-class correlation coefficient (ICC). Results: Forty-nine participants aged 56 ± 19 years were included. Nineteen had hypertension (38%). We did not observe a significant difference in either systolic (SBP) or diastolic blood pressure (DBP) pressure measurements between the observers and the device. The mean difference was -0.09 mmHg (95% confidence intervals (CI)-0.9 to 0.7) for SBP and -0.9 mmHg (95% CI -1.7 to -0.13) for DBP. The RC for SBP (6.2, 5.2 and 5.8 mmHg) and DBP (4.7, 4.2 y 5.2 mmHg) was similar between the observers and the device. The ICC for SBP was 0.990 (95% CI 0.983 to 0.995, p < 0.01) and 0.986 (95% CI 0.977 to 0.991, p < 0.01) for DBP. Conclusions: There was a high level of agreement and similar measurement repeatability in the measurements performed by the automatic device and the mercurial sphygmomanometer. No differences in BP measurements were observed.
MeSH term(s)	Blood Pressure Determination/instrumentation ; Blood Pressure Determination/methods ; Blood Pressure Monitors ; Cross-Sectional Studies ; Female ; Humans ; Hypertension/diagnosis ; Male ; Middle Aged ; Reproducibility of Results
Language	Spanish
Publishing date	2018-02
Publishing country	Chile
Document type	Comparative Study ; Journal Article
ZDB-ID	732136-3
ISSN	0717-6163 ; 0034-9887
ISSN (online)	0717-6163
ISSN	0034-9887
DOI	10.4067/s0034-98872018000200190
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Zs.B 402: Show issues

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