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  1. Article ; Online: Update on the diagnosis and treatment of choroidal hemangioma.

    García Caride, S / Fernández-Vigo, J I / Valverde-Megías, A

    Archivos de la Sociedad Espanola de Oftalmologia

    2023  Volume 98, Issue 5, Page(s) 281–291

    Abstract: Choroidal hemangioma (CH) is a benign vascular tumor dependent on the choroid. Two types of lesions are distinguished: circumscribed (CCH), the most frequent variant, and diffuse (DCH), normally associated with Sturge-Weber syndrome. HCC appears as an ... ...

    Abstract Choroidal hemangioma (CH) is a benign vascular tumor dependent on the choroid. Two types of lesions are distinguished: circumscribed (CCH), the most frequent variant, and diffuse (DCH), normally associated with Sturge-Weber syndrome. HCC appears as an orange mass that can present asymptomatically, however, when it produces symptoms, the most frequent is decreased visual acuity due to neurosensory retinal detachment. Due to its benign nature, only those that produce symptoms should be eligible for treatment. Knowledge of this pathology and its correct differential diagnosis is very relevant to establish the appropriate diagnosis and treatment, avoiding unnecessary treatments. There is currently a wide variety of multimodal diagnostic imaging tests that allow us to identify and adequately monitor this tumor. In addition, in recent years, there has been a change in the paradigm of the treatment of these tumors thanks to the use of photodinamic therapy, which has led to a significant improvement in the visual prognosis of these patients. This has been due to the use of photodynamic therapy as the treatment of choice for HCC.
    MeSH term(s) Humans ; Choroid Neoplasms/diagnosis ; Choroid Neoplasms/therapy ; Fluorescein Angiography ; Hemangioma/diagnosis ; Hemangioma/therapy ; Hemangioma/pathology ; Sturge-Weber Syndrome/diagnosis ; Sturge-Weber Syndrome/therapy ; Sturge-Weber Syndrome/complications
    Language English
    Publishing date 2023-04-14
    Publishing country Spain
    Document type Journal Article ; Review
    ISSN 2173-5794
    ISSN (online) 2173-5794
    DOI 10.1016/j.oftale.2023.04.006
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  2. Article ; Online: Corneal birth trauma with free-floating Descemet's roll. Endothelial migration or transfer?

    Garcia-Caride, S / Diaz Valle, D / Arino Gutierrez, M / Méndez Fernández, R

    Journal francais d'ophtalmologie

    2022  Volume 45, Issue 8, Page(s) e385–e387

    MeSH term(s) Corneal Diseases/surgery ; Descemet Membrane ; Descemet Stripping Endothelial Keratoplasty ; Endothelium, Corneal ; Fuchs' Endothelial Dystrophy/surgery ; Humans
    Language English
    Publishing date 2022-05-20
    Publishing country France
    Document type Letter
    ZDB-ID 426662-6
    ISSN 1773-0597 ; 0181-5512
    ISSN (online) 1773-0597
    ISSN 0181-5512
    DOI 10.1016/j.jfo.2021.11.023
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  3. Article ; Online: Corneal aberrations in primary congenital glaucoma and its visual correlation.

    Ly-Yang, Fernando / Morales-Fernandez, L / Garcia-Bella, J / Garcia-Caride, S / Santos-Bueso, E / Saenz-Frances, F / Fernandez-Vigo, J I / Garcia-Feijoo, J / Martinez-de-la-Casa, J M

    International ophthalmology

    2024  Volume 44, Issue 1, Page(s) 209

    MeSH term(s) Humans ; Visual Acuity ; Female ; Male ; Cornea/abnormalities ; Cornea/pathology ; Cornea/diagnostic imaging ; Corneal Wavefront Aberration/physiopathology ; Corneal Wavefront Aberration/diagnosis ; Infant ; Glaucoma/congenital ; Glaucoma/physiopathology ; Glaucoma/diagnosis ; Intraocular Pressure/physiology ; Hydrophthalmos/diagnosis ; Hydrophthalmos/physiopathology ; Hydrophthalmos/surgery ; Child, Preschool
    Language English
    Publishing date 2024-04-29
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-024-03150-5
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  4. Article ; Online: Combined cataract surgery and lamellar endothelial keratoplasty in iridocorneal endothelial syndrome.

    García Caride, S / Cuiña Sardiña, R / Perucho González, L

    Archivos de la Sociedad Espanola de Oftalmologia

    2020  Volume 95, Issue 9, Page(s) 451–454

    Abstract: The case is reported of a 59-year-old woman, who reported decreased visual acuity (VA) in the left eye (LE). On examination, a corrected VA of finger count/ 30cm was observed in LE. Corneal oedema and folds in the Descemet's membrane were observed using ... ...

    Title translation Cirugía combinada de catarata y queratoplastia lamelar endotelial en el síndrome iridocórneo endotelial.
    Abstract The case is reported of a 59-year-old woman, who reported decreased visual acuity (VA) in the left eye (LE). On examination, a corrected VA of finger count/ 30cm was observed in LE. Corneal oedema and folds in the Descemet's membrane were observed using the slit lamp. Anterior synechiae, iris atrophy, and corectopia were also found. Iridocorneal endothelial syndrome (ICE) was diagnosed. The treatment option was a combination of cataract surgery and automated endothelial keratoplasty with Descemet's membrane dissection (DSAEK). There were no complications during the operation, with a successful anatomical and functional recovery, with a VA of 0,8 being observed after one year. This result supports the efficacy of DSAEK in ICE syndrome, encouraging more studies to be carried out that should also support its efficacy in this syndrome.
    Language Spanish
    Publishing date 2020-06-25
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5794
    ISSN (online) 2173-5794
    DOI 10.1016/j.oftal.2020.05.022
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  5. Article ; Online: Multiple retrograde retinal artery emboli as a complication of coil embolization in the region of the ophthalmic artery.

    García Caride, S / López Guajardo, L / Donate López, J

    Journal francais d'ophtalmologie

    2020  Volume 44, Issue 1, Page(s) e51–e54

    MeSH term(s) Embolism/diagnosis ; Embolism/etiology ; Embolization, Therapeutic/adverse effects ; Humans ; Ophthalmic Artery ; Retinal Artery/diagnostic imaging
    Language English
    Publishing date 2020-11-13
    Publishing country France
    Document type Letter
    ZDB-ID 426662-6
    ISSN 1773-0597 ; 0181-5512
    ISSN (online) 1773-0597
    ISSN 0181-5512
    DOI 10.1016/j.jfo.2020.03.010
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  6. Article ; Online: Hypertensive and HLA-B27 negative uveitis: Disease course and complications.

    García Caride, S / Ginés Gallego, C / Gegúndez Fernández, J A / Díaz Valle, D

    Archivos de la Sociedad Espanola de Oftalmologia

    2021  Volume 96, Issue 11, Page(s) 587–592

    Abstract: Purpose: To perform a retrospective analysis on patients with HLA-B27 negative hypertensive acute anterior uveitis. Aqueous humor samples were obtained on which a polymerase chain reaction (PCR) test was performed. The patients were then classified into ...

    Abstract Purpose: To perform a retrospective analysis on patients with HLA-B27 negative hypertensive acute anterior uveitis. Aqueous humor samples were obtained on which a polymerase chain reaction (PCR) test was performed. The patients were then classified into 3 groups depending on whether they were positive for cytomegalovirus (CMV) or herpesvirus (HSV-VZV) or negative for both.
    Material and methods: Different variables were collected in successive visits (baseline, 3, 6, and 12 months). The variables were age, sex, visual acuity, intraocular pressure (IOP), cells in the anterior chamber, retro-keratic precipitates, hypotensive treatment, glaucoma or retina surgery, corneal transplantation, and central thickness of the retinal nerve fiber layer.
    Results: The sample was 36 patients, with a mean age of 59.78 ± 15.26 years. The mean baseline IOP value was 40 ± 10.42 mmHg in the CMV group compared to 23.8 ± 10.4 mmHg in the HSV-VZV, and 22.65 ± 9.9 mmHg in the negative group. The baseline frequency of retro-keratic precipitates, hypotensive treatment, glaucoma surgery, and corneal transplantation was higher in CMV positives. At one year, the loss of retinal nerve fiber layer and glaucoma surgery was greater in the negative group. In the 3 groups, there was a direct and positive correlation between IOP and inflammation in the anterior chamber. Being 0.94 (P = .05) for the positive for CMV, 0.24 (P = .75) in that of HSV-VZV, and 0.98 (P = .17) in the negative group.
    Conclusions: HLA-B27 negative hypertensive acute anterior uveitis with CMV positive has a more aggressive initial presentation. However, after one year, the glaucomatous damage is less than in the negative group. In hypertensive acute anterior uveitis, when inflammation in anterior chamber is controlled then IOP is also controlled.
    MeSH term(s) Adult ; Aged ; Cytomegalovirus ; HLA-B27 Antigen/genetics ; Humans ; Middle Aged ; Retrospective Studies ; Uveitis ; Uveitis, Anterior
    Chemical Substances HLA-B27 Antigen
    Language English
    Publishing date 2021-06-12
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5794
    ISSN (online) 2173-5794
    DOI 10.1016/j.oftale.2021.01.005
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  7. Article ; Online: Ocular involvement in two siblings with Cohen's syndrome.

    Peña Urbina, P / García Caride, S / Gómez de Liaño Sánchez, R / Domingo Gordo, B

    Journal francais d'ophtalmologie

    2021  Volume 44, Issue 7, Page(s) e437–e440

    MeSH term(s) Child ; Developmental Disabilities ; Fingers ; Humans ; Intellectual Disability ; Muscle Hypotonia ; Siblings
    Language English
    Publishing date 2021-04-02
    Publishing country France
    Document type Letter
    ZDB-ID 426662-6
    ISSN 1773-0597 ; 0181-5512
    ISSN (online) 1773-0597
    ISSN 0181-5512
    DOI 10.1016/j.jfo.2020.10.004
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  8. Article ; Online: Hypertensive and HLA-B27 negative uveitis: Disease course and complications.

    García Caride, S / Ginés Gallego, C / Gegúndez Fernández, J A / Díaz Valle, D

    Archivos de la Sociedad Espanola de Oftalmologia

    2021  

    Abstract: Purpose: To perform a retrospective analysis on patients with HLA-B27 negative hypertensive acute anterior uveitis. Aqueous humor samples were obtained on which a polymerase chain reaction (PCR) test was performed. The patients were then classified into ...

    Title translation Evolución y complicaciones en pacientes con uveítis hipertensivas HLA-B27 negativas.
    Abstract Purpose: To perform a retrospective analysis on patients with HLA-B27 negative hypertensive acute anterior uveitis. Aqueous humor samples were obtained on which a polymerase chain reaction (PCR) test was performed. The patients were then classified into 3 groups depending on whether they were positive for cytomegalovirus (CMV) or herpesvirus (HSV-VZV) or negative for both.
    Material and methods: Different variables were collected in successive visits (baseline, 3, 6, and 12 months). The variables were age, sex, visual acuity, intraocular pressure (IOP), cells in the anterior chamber, retro-keratic precipitates, hypotensive treatment, glaucoma or retina surgery, corneal transplantation, and central thickness of the retinal nerve fiber layer.
    Results: The sample was 36 patients, with a mean age of 59.78±15.26 years. The mean baseline IOP value was 40±10.42mmHg in the CMV group compared to 23.8±10.4mmHg in the HSV-VZV, and 22.65±9.9mmHg in the negative group. The baseline frequency of retro-keratic precipitates, hypotensive treatment, glaucoma surgery, and corneal transplantation was higher in CMV positives. At one year, the loss of retinal nerve fiber layer and glaucoma surgery was greater in the negative group. In the 3 groups, there was a direct and positive correlation between IOP and inflammation in the anterior chamber. Being 0.94 (P=.05) for the positive for CMV, 0.24 (P=.75) in that of HSV-VZV, and 0.98 (P=.17) in the negative group.
    Conclusions: HLA-B27 negative hypertensive acute anterior uveitis with CMV positive has a more aggressive initial presentation. However, after one year, the glaucomatous damage is less than in the negative group. In hypertensive acute anterior uveitis, when inflammation in anterior chamber is controlled then IOP is also controlled.
    Language Spanish
    Publishing date 2021-03-17
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5794
    ISSN (online) 2173-5794
    DOI 10.1016/j.oftal.2021.01.006
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  9. Article ; Online: Preseptal cellulitis, intraocular inflammatory reaction and corneal persistent epithelial defect as side effects of avapritinib.

    García Caride, Sara / Marquina, Gloria / Díaz Valle, David

    Anti-cancer drugs

    2021  Volume 32, Issue 10, Page(s) 1127–1130

    Abstract: Avapritinib is a tyrosine kinase inhibitor currently being investigated on clinical trials for the treatment of unresectable or metastatic gastrointestinal stromal tumour (GIST). It has been recently approved by the Food and Drug Administration and the ... ...

    Abstract Avapritinib is a tyrosine kinase inhibitor currently being investigated on clinical trials for the treatment of unresectable or metastatic gastrointestinal stromal tumour (GIST). It has been recently approved by the Food and Drug Administration and the European Medicines Agency for the treatment of unresectable or metastatic GIST harbouring PDGFRa Exon 18 mutation and by the European Medicines Agency for the treatments of unresectable or metastatic GIST harbouring the PDGFRa D842V mutation. We report a clinical case of a 76-year-old female, diagnosed with a stage IV GIST, treated with avapritinib 300 mg once daily. through compassionate use who experienced an intraocular side effect not previously reported avapritinib. She developed preseptal cellulitis on her right eye following 2 months of treatment with avapritinib and, subsequently evolved to an intraocular inflammatory reaction and persistent corneal epithelial defect. The treatment with avapritinib was stopped and the patient received corticosteroid and corneal regenerating agents. The symptoms resolved within 1 month and the patient has remained on stable disease at two subsequent adjusted avapritinib doses (100 mg once daily) for over 1 year.
    MeSH term(s) Aged ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Cellulitis/chemically induced ; Epithelium, Corneal ; Eye Diseases/chemically induced ; Female ; Gastrointestinal Stromal Tumors/drug therapy ; Gastrointestinal Stromal Tumors/pathology ; Humans ; Inflammation/chemically induced ; Neoplasm Metastasis ; Neoplasm Staging ; Pyrazoles/adverse effects ; Pyrazoles/therapeutic use ; Pyrroles/adverse effects ; Pyrroles/therapeutic use ; Receptor, Platelet-Derived Growth Factor alpha/genetics ; Triazines/adverse effects ; Triazines/therapeutic use
    Chemical Substances Antineoplastic Agents ; Pyrazoles ; Pyrroles ; Triazines ; avapritinib (513P80B4YJ) ; Receptor, Platelet-Derived Growth Factor alpha (EC 2.7.10.1)
    Language English
    Publishing date 2021-07-19
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1065301-6
    ISSN 1473-5741 ; 0959-4973
    ISSN (online) 1473-5741
    ISSN 0959-4973
    DOI 10.1097/CAD.0000000000001123
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    Zs.A 3125: Show issues Location:
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  10. Article ; Online: Useful technique for pupillometry in difficult cases.

    García Caride, Sara / Valverde Megías, Alicia / Jacobo, Enriquez Fuentes / Blanca, Domingo Gordo

    Acta ophthalmologica

    2023  Volume 101, Issue 5, Page(s) 582–584

    MeSH term(s) Humans ; Pupil ; Reflex, Pupillary ; Physical Examination
    Language English
    Publishing date 2023-01-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2408333-1
    ISSN 1755-3768 ; 1755-375X
    ISSN (online) 1755-3768
    ISSN 1755-375X
    DOI 10.1111/aos.15632
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