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  1. Article ; Online: Systematic Review and Meta-Analysis of the Outcome of Different Treatments for Innominate Artery Stenosis or Occlusion.

    Catasta, Alexandra / Bianchini Massoni, Claudio / Perini, Paolo / Carli, Anna Giulia / Freyrie, Antonio

    Angiology

    2023  Volume 75, Issue 4, Page(s) 314–322

    Abstract: The present study reported the outcomes of different treatments for innominate artery (IA) atherosclerotic stenosis or occlusion. We performed a systematic review of the literature (4 database searched; last search February 2022), including articles with ...

    Abstract The present study reported the outcomes of different treatments for innominate artery (IA) atherosclerotic stenosis or occlusion. We performed a systematic review of the literature (4 database searched; last search February 2022), including articles with ≥5 patients. We performed meta-analyses of proportions for different postoperative outcomes. Fourteen studies were included (656 patients; 396 underwent surgery, 260 endovascular procedures). IA lesions were asymptomatic in 9.6% (95% CI 4.6-14.6). Overall estimated technical success (TS) rate was 91.7% (95% CI 86.9-96.4); weighted TS rate was 86.8% (95% CI 75-98.6) in the surgical group (SG), 97.1% (95% CI 94.6-99.7) in the endovascular group (EG). Postoperative stroke in SG was 2.5% (95% CI 1-4.1) and 2.1% in EG (95% CI .3-3.8). Overall, 30-day occlusion was estimated .9% (95% CI 0-1.8) in SG and .7% (95% CI 0-1.7) in EG. Thirty-day mortality was 3.4% (95% CI .9-5.8) in SG and .7% (95% CI 0-1.7) in EG. Estimated mean follow-up after intervention was 65.5 months (95% CI 45.5-85.5) in SG and 22.4 months (95% CI 14.72-30.16) in EG. During follow-up, restenosis in SG were 2.8% (95% CI .5-5.1) and 16.6% (95% CI 5- 28.1) in EG. In conclusion, the endovascular approach seems to offer good short to mid-term outcomes, but with a higher rate of restenosis during follow-up.
    MeSH term(s) Humans ; Constriction, Pathologic/surgery ; Brachiocephalic Trunk/surgery ; Endovascular Procedures ; Atherosclerosis/therapy ; Blood Vessel Prosthesis Implantation ; Treatment Outcome ; Stents
    Language English
    Publishing date 2023-03-09
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 80040-5
    ISSN 1940-1574 ; 0003-3197
    ISSN (online) 1940-1574
    ISSN 0003-3197
    DOI 10.1177/00033197231162179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui IV Zs.61: Show issues Location:
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  2. Article ; Online: Fatal severe persistent pulmonary hypertension with lung microvasculature parietal hyperplasia in a neonate with congenital cytomegalovirus infection treated in-utero with valacyclovir: A case report.

    Fernicola, Federica / Carli, Anna / Arienti, Francesca / Viola Vasarri, Maria / Lanteri, Laura / Scandella, Gaia / Poletti De Chaurand, Valeria / Zicoia, Marianna / Iozzi, Lucia / Gorla, Sonia / Luisa Ventura, Maria / Locatelli, Anna / Sinelli, Mariateresa / Ornaghi, Sara

    European journal of obstetrics, gynecology, and reproductive biology

    2024  Volume 294, Page(s) 245–246

    MeSH term(s) Infant, Newborn ; Humans ; Hypertension, Pulmonary/drug therapy ; Hypertension, Pulmonary/etiology ; Valacyclovir/therapeutic use ; Hyperplasia ; Cytomegalovirus Infections/complications ; Cytomegalovirus Infections/drug therapy ; Lung/diagnostic imaging ; Microvessels ; Antiviral Agents/therapeutic use
    Chemical Substances Valacyclovir (MZ1IW7Q79D) ; Antiviral Agents
    Language English
    Publishing date 2024-01-11
    Publishing country Ireland
    Document type Case Reports ; Letter
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2024.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 837: Show issues Location:
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  3. Article ; Online: Indirect impact of SARS-CoV-2 pandemic on incidence of maternal primary cytomegalovirus and Toxoplasma gondii infection in pregnancy.

    Vasarri, Maria Viola / Fernicola, Federica / Arienti, Francesca / Carli, Anna / Colciago, Elisabetta / Locatelli, Anna / Trotta, Michele / Procopio, Angelica / Zammarchi, Lorenzo / Ornaghi, Sara

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2024  

    Abstract: Objective: Public health interventions promoted during the SARS-CoV-2 pandemic to control viral spread have impacted the occurrence of other communicable disease. Yet no studies have focused on perinatal infections with the potential for neonatal ... ...

    Abstract Objective: Public health interventions promoted during the SARS-CoV-2 pandemic to control viral spread have impacted the occurrence of other communicable disease. Yet no studies have focused on perinatal infections with the potential for neonatal sequelae, including cytomegalovirus (CMV) and Toxoplasma gondii (TG). Here we investigate whether incidence rates of maternal primary CMV and TG infection in pregnancy were affected by the implementation of pandemic-related public health measures.
    Methods: A retrospective study including all pregnant women with confirmed primary CMV or TG infection in pregnancy, managed between 2018 and 2021 at two university centers. The incidence rate was calculated as the number of CMV and TG infections per 100 consultations with a 95% confidence interval (CI). Data were compared between pre-pandemic (2018-2019) and pandemic (2020 and 2021) years. The Newcombe Wilson with Continuity Correction method was employed to compare incidence rates.
    Results: The study population included 215 maternal primary CMV and 192 TG infections. Rate of maternal primary CMV infection decreased in 2021 compared with 2018-2019 (4.49% vs 6.40%, attributable risk [AR] 1.92, P = 0.019). By contrast, the rate of TG infection substantially increased in 2020 (6.95% vs 4.61%, AR 2.34, P = 0.006). Close contact with cats was more common among patients with TG infection in 2020 and 2021 than among pre-pandemic TG-infected women (26.3% and 24.4% vs 13.3%, P = 0.013).
    Conclusion: Pandemic-related public health interventions and associated behavioral and lifestyle changes exerted a divergent effect on the incidence of primary CMV and TG infection in pregnancy, likely due to modulation of exposure to risk factors for these infections.
    Language English
    Publishing date 2024-04-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.15534
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    Zs.A 355: Show issues Location:
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    Zs.MO 183: Show issues

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  4. Article ; Online: Loss of Prosthetic Aortic Valve during TAVI Procedure: Endovascular Treatment in Emergent Setting.

    Carli, Anna Giulia / Perini, Paolo / Vignali, Luigi / Bianchini Massoni, Claudio / Fanelli, Mara / Freyrie, Antonio

    Annals of vascular surgery

    2021  Volume 73, Page(s) 585–588

    Abstract: Background: Transcatheter aortic valve implantation (TAVI) has proven over the years to be a viable alternative to open surgery. A rare but severe complication is represented by the valve migration. We report a case of TAVI complication due to the loss ... ...

    Abstract Background: Transcatheter aortic valve implantation (TAVI) has proven over the years to be a viable alternative to open surgery. A rare but severe complication is represented by the valve migration. We report a case of TAVI complication due to the loss of the prosthetic valve in the abdominal aorta treated by endovascular approach.
    Methods: An 88-year-old patient with severe aortic valve stenosis, symptomatic for dyspnea was proposed for a TAVI because considered at high risk for surgery. During the TAVI procedure, the undeployed device (Edwards SAPIEN 3 - Edwards Lifesciences, Irvine, CA, USA) detached from its delivery system. Several attempts to withdraw the valve fluctuating in the aorta into its supporting system were performed without success. An emergency endovascular treatment was promptly planned to obtain the exclusion from the flow of the embolized valve. Under local anaesthesia, through the percutaneous femoral access already present, a tube aortic endograft (Endurant
    Conclusions: In case of intraprocedural loss of an undeplyed valve during TAVI, the valve fixing through endograft deployment in infrarenal aorta is a possible solution.
    MeSH term(s) Aged, 80 and over ; Aorta, Abdominal/diagnostic imaging ; Aortic Valve/diagnostic imaging ; Aortic Valve/physiopathology ; Aortic Valve/surgery ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/physiopathology ; Aortic Valve Stenosis/surgery ; Endovascular Procedures ; Foreign-Body Migration/diagnostic imaging ; Foreign-Body Migration/etiology ; Foreign-Body Migration/therapy ; Heart Valve Prosthesis ; Humans ; Male ; Severity of Illness Index ; Transcatheter Aortic Valve Replacement/adverse effects ; Transcatheter Aortic Valve Replacement/instrumentation ; Treatment Outcome
    Language English
    Publishing date 2021-02-05
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 1027366-9
    ISSN 1615-5947 ; 0890-5096
    ISSN (online) 1615-5947
    ISSN 0890-5096
    DOI 10.1016/j.avsg.2020.12.044
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    Zs.A 2882: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Letter to Editor: Asymptomatic CMV infection at birth following maternal infection, valacyclovir treatment, and a subsequent negative amniocentesis.

    Fernicola, Federica / Carli, Anna / Arienti, Francesca / Vasarri, Maria Viola / Lanteri, Laura / Scandella, Gaia / De Chaurand, Valeria Poletti / Zicoia, Marianna / Iozzi, Lucia / Ventura, Maria Luisa / Sinelli, Mariateresa / Locatelli, Anna / Ornaghi, Sara

    European journal of obstetrics, gynecology, and reproductive biology

    2023  Volume 292, Page(s) 268–269

    MeSH term(s) Pregnancy ; Infant, Newborn ; Female ; Humans ; Valacyclovir/therapeutic use ; Amniocentesis ; Antiviral Agents/therapeutic use ; Cytomegalovirus Infections/diagnosis ; Cytomegalovirus Infections/drug therapy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/drug therapy ; Infectious Disease Transmission, Vertical/prevention & control
    Chemical Substances Valacyclovir (MZ1IW7Q79D) ; Antiviral Agents
    Language English
    Publishing date 2023-11-21
    Publishing country Ireland
    Document type Letter ; Comment
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2023.11.020
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    Zs.A 837: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  6. Article: Anterior pituitary function may predict functional and cognitive outcome in patients with traumatic brain injury undergoing rehabilitation.

    Bondanelli, Marta / Ambrosio, Maria Rosaria / Cavazzini, Lorenza / Bertocchi, Amedeo / Zatelli, Maria Chiara / Carli, Anna / Valle, Domenico / Basaglia, Nino / Uberti, Ettore C Degli

    Journal of neurotrauma

    2007  Volume 24, Issue 11, Page(s) 1687–1697

    Abstract: Traumatic brain injury (TBI) is the leading cause of death and disability in young adults. Growth hormone-insulin-like growth factor I (GH-IGF-I) system has an important role in the recovery of the central nervous system. The aim of the study was to ... ...

    Abstract Traumatic brain injury (TBI) is the leading cause of death and disability in young adults. Growth hormone-insulin-like growth factor I (GH-IGF-I) system has an important role in the recovery of the central nervous system. The aim of the study was to evaluate the relationship between pituitary function (in particular, the GH-IGF-I axis) and outcome from TBI. We studied 72 patients (56 males; mean age 37.2 +/- 1.8 years) receiving rehabilitation after TBI. According to the Glasgow Coma Scale (GCS), 10 patients had moderate and 52 severe TBI. Ten patients had growth hormone GH deficiency (GHD), 10 LH-FSH, three TSH, and three ACTH deficiency. Overall pituitary dysfunction occurred in 22 (30.5%) patients, with anterior hypopituitarism in 19 (26.4%), isolated diabetes insipidus in one, and isolated hyperprolactinemia in two. GH response to GHRH + ARG (arginine) positively correlated with Functional Independence Measure (FIM D; r = 0.267, p < 0.02) and Level of Cognitive Functioning Scale (LCFS D; r = 0.287, p < 0.01) at discharge, and negatively with Disability Rating Score at discharge (DRS D; r = -0.324, p < 0.005). Unfavorable outcome measures (FIM D, LCFS D, and DRS D) occurred in patients with hypopituitarism as compared with normal pituitary function (p < 0.05). Multiple regression analysis identified both GCS (p < 0.005) and GH peak (p < 0.05) as strong independent predictors of outcome. In conclusion, recovery after TBI may be negatively influenced by concomitant pituitary dysfunction. The GH peak value is an independent predictor of outcome, indicating that recovery during an intensive rehabilitation program after TBI may be positively influenced by normal GH secretion.
    MeSH term(s) Adolescent ; Adult ; Aged ; Brain Injuries/complications ; Brain Injuries/psychology ; Brain Injuries/rehabilitation ; Cognition/physiology ; Cohort Studies ; Female ; Glasgow Coma Scale ; Human Growth Hormone/blood ; Humans ; Insulin-Like Growth Factor I/metabolism ; Male ; Middle Aged ; Motor Activity/physiology ; Pituitary Diseases/etiology ; Pituitary Diseases/physiopathology ; Pituitary Diseases/psychology ; Predictive Value of Tests ; Recovery of Function/physiology ; Treatment Outcome
    Chemical Substances Human Growth Hormone (12629-01-5) ; Insulin-Like Growth Factor I (67763-96-6)
    Language English
    Publishing date 2007-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645092-1
    ISSN 1557-9042 ; 0897-7151
    ISSN (online) 1557-9042
    ISSN 0897-7151
    DOI 10.1089/neu.2007.0343
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    Zs.A 2016: Show issues Location:
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  7. Article ; Online: Predictors of pituitary dysfunction in patients surviving ischemic stroke.

    Bondanelli, Marta / Ambrosio, Maria Rosaria / Carli, Anna / Bergonzoni, Antonella / Bertocchi, Amedeo / Zatelli, Maria Chiara / Ceruti, Stefano / Valle, Domenico / Basaglia, Nino / degli Uberti, Ettore C

    The Journal of clinical endocrinology and metabolism

    2010  Volume 95, Issue 10, Page(s) 4660–4668

    Abstract: Background: Stroke is a leading cause of death in industrialized countries, representing the main cause of long-term disability. Recent studies indicate that hypopituitarism may be observed after an acute stroke.: Objective: The aim was to ... ...

    Abstract Background: Stroke is a leading cause of death in industrialized countries, representing the main cause of long-term disability. Recent studies indicate that hypopituitarism may be observed after an acute stroke.
    Objective: The aim was to prospectively investigate incidence and pattern of pituitary dysfunction in patients suffering ischemic stroke and to assess the predictive value of different clinical and radiological parameters for hypopituitarism.
    Patients and methods: We assessed endocrine, clinical, radiological, and functional parameters in 56 patients (34 males; mean age, 64.8 ± 1.3 yr; mean body mass index, 25.8 ± 0.45 kg/m(2)) at 1-3 months (visit 1) and 12-15 months (visit 2) after an ischemic stroke.
    Results: At visit 1, hypopituitarism was detected in 20 (35.7%) of 56 stroke patients, with multiple deficits in three and isolated deficits in 17. At visit 2, hypopituitarism was detected in 18 (37.5%) of 48 stroke patients, with multiple deficits in two. Four patients with previously diagnosed isolated GH or LH/FSH deficit exhibited normal pituitary function, whereas GH deficiency was newly diagnosed in three cases. Hypopituitarism was associated with worse outcome. We identified both clinical (preexisting diabetes mellitus, medical complications during hospitalization) and radiological (Alberta Stroke Programme Early CT Score ≤ 7) parameters as major risk factors for developing hypopituitarism after ischemic stroke.
    Conclusions: Hypopituitarism may associate with ischemic stroke in one third of cases and persist in a long-term period, aggravating the functional outcome. We identified specific risk factors for hypopituitarism after stroke, which may help to select patients needing an accurate endocrine evaluation to improve stroke outcome.
    MeSH term(s) Aged ; Brain Ischemia/complications ; Brain Ischemia/diagnostic imaging ; Brain Ischemia/epidemiology ; Brain Ischemia/rehabilitation ; Female ; Humans ; Hypopituitarism/epidemiology ; Hypopituitarism/etiology ; Incidence ; Male ; Middle Aged ; Pituitary Diseases/diagnosis ; Pituitary Diseases/diagnostic imaging ; Pituitary Diseases/epidemiology ; Pituitary Diseases/etiology ; Pituitary Function Tests ; Predictive Value of Tests ; Prognosis ; Radiography ; Risk Factors ; Stroke/complications ; Stroke/diagnostic imaging ; Stroke/epidemiology ; Stroke Rehabilitation ; Survivors/statistics & numerical data
    Language English
    Publishing date 2010-10
    Publishing country United States
    Document type Evaluation Studies ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/jc.2010-0611
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