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Article ; Online: Reducing Central Line Utilization by Peripherally Infusing Vasopressors.

Coyer, Ben / Carlucci, Melissa

Dimensions of critical care nursing : DCCN

2023 Volume 42, Issue 3, Page(s) 131–136

Abstract: Background: Central line-associated bloodstream infection is a preventable contributor to excess death and excess cost in the health care system. Vasopressor infusion is one of the primary reasons for central line placement. In the medical intensive ... ...

Abstract	Background: Central line-associated bloodstream infection is a preventable contributor to excess death and excess cost in the health care system. Vasopressor infusion is one of the primary reasons for central line placement. In the medical intensive care unit (MICU) at an academic medical center, there was no standard practice for peripheral versus central infusion of vasopressors. Objective: The objective of this quality improvement project was to implement an evidence-based, nurse-driven protocol to guide the peripheral infusion of vasopressors. The goal was to reduce central line utilization by 10%. Methods: Education on the protocol was provided to the MICU nurses, MICU residents, and crisis nurses, followed by a 16-week implementation period. Nursing staff were also surveyed preimplementation and postimplementation of the protocol. Results: Central line utilization was reduced by 37.9%, and there were no central line-associated bloodstream infections recorded during project implementation. Most of the nursing staff indicated that use of the protocol increased their confidence in administering vasopressors without a central line. No significant extravasation events occurred. Discussion: Although a causal link between implementation of this protocol and reduction of central line utilization cannot be established, the reduction is clinically meaningful given the known risks of central lines. Increased nursing staff confidence also provides support for continued use of the protocol. Conclusion: A nurse-driven protocol to guide the peripheral infusion of vasopressors can be effectively implemented into nursing practice.
MeSH term(s)	Humans ; Intensive Care Units ; Quality Improvement ; Sepsis/prevention & control ; Nurses ; Catheterization, Peripheral ; Physicians
Language	English
Publishing date	2023-03-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	632780-1
ISSN	1538-8646 ; 0730-4625
ISSN (online)	1538-8646
ISSN	0730-4625
DOI	10.1097/DCC.0000000000000576
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Article ; Online: Prevalence of Orthorexia Nervosa in a sample of italian young adults.

Lupi, M / Carano, A / Carlucci, M / Acciavatti, T / Pettorruso, M / Cinosi, E / De Berardis, D / Martinotti, G

La Clinica terapeutica

2024 Volume 175, Issue 2, Page(s) 125–127

Abstract: Abstract: There is only limited epidemiological information on Orthorexia Nervosa; the aim of the present study is, therefore, to assess the prevalence of ON in a population of young adults and to identify possible specific features and eventual ... ...

Abstract	Abstract: There is only limited epidemiological information on Orthorexia Nervosa; the aim of the present study is, therefore, to assess the prevalence of ON in a population of young adults and to identify possible specific features and eventual psychopatological dimensions. 1317 participants (732 females and 585 males; mean age 22.36 yrs) completed a battery containing the orthorexia measure (ORTHO-15), statements about demographic characteristics as well as physiological parameters. The mean ORTO-15 score was 31.89; considering the cut-off of 40 in the reference test, our results showed a 11.9% prevalence of ON. Analyzing the characteristics of the orthorexic group, the prevalence in females compared to males appears to be statistically very significant (115 vs 43; 72.8% vs 27.2%); moreover shows higher and statistically significant scores in each of the 15 items of the reference test compared to the non-orthorexic group. Our data confirming that ON might be a relevant and potentially underestimate phenomenon in the community. Further studies are warranted in order to explore the diagnostic boundaries of this syndrome, its course and outcome, and the possible therapeutic strategies.
MeSH term(s)	Male ; Female ; Humans ; Young Adult ; Adult ; Health Behavior ; Orthorexia Nervosa ; Feeding and Eating Disorders/epidemiology ; Prevalence ; Feeding Behavior ; Surveys and Questionnaires ; Italy/epidemiology
Language	English
Publishing date	2024-04-03
Publishing country	Italy
Document type	Observational Study
ZDB-ID	123320-8
ISSN	1972-6007 ; 0009-9074
ISSN (online)	1972-6007
ISSN	0009-9074
DOI	10.7417/CT.2024.5044
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Article: First report of

Habib, Wassim / Carlucci, Mariangela / Fasano, Roberto / Nigro, Franco

Plant disease

2023

Abstract: First report ... ...

Abstract	First report of
Language	English
Publishing date	2023-11-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	754182-x
ISSN	0191-2917
ISSN	0191-2917
DOI	10.1094/PDIS-05-23-1011-PDN
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Article ; Online: Creation of a critical care NP onboarding program.

Stephens, Katie / Carlucci, Melissa / Duchnowska, Anna / Blumenthal, Rachel / Dickens, Carolyn

The Nurse practitioner

2023 Volume 48, Issue 8, Page(s) 7–10

MeSH term(s)	Humans ; Inservice Training ; Critical Care
Language	English
Publishing date	2023-07-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	604085-8
ISSN	1538-8662 ; 0361-1817
ISSN (online)	1538-8662
ISSN	0361-1817
DOI	10.1097/01.NPR.0000000000000085
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Article ; Online: Breaking Bad News via Telehealth: Simulation Training for Nurse Practitioner Students.

Berta, Mara / Burt, Leah / Carlucci, Melissa / Corbridge, Susan

The Journal of nursing education

2022 Volume 61, Issue 9, Page(s) 528–532

Abstract: Background: The coronavirus disease 2019 (COVID-19) pandemic demonstrated educators must consider students' future practice will involve patient communication via telehealth, including breaking bad news.: Method: This mixed-methods analysis was ... ...

Abstract	Background: The coronavirus disease 2019 (COVID-19) pandemic demonstrated educators must consider students' future practice will involve patient communication via telehealth, including breaking bad news. Method: This mixed-methods analysis was conducted among 33 nurse practitioner (NP) students at two universities. Questionnaires were analyzed before and after a simulation training session with standardized patients to determine students' perceptions, learning satisfaction, confidence, and self-rated preparedness for delivering bad news via telehealth. Results: Students' self-rated levels of preparedness for delivering bad news were higher after participating in the simulation. Students found the teaching methods to be effective, enjoyable, motivating, and suitable to individual learning styles. Two themes emerged that described students' perceptions of the experience: valuable simulation processes and multifaceted learning applicable to future NP practice. Conclusion: Breaking bad news via virtual platforms is new and challenging. Findings suggest this simulation experience provided a valuable tool for augmenting didactic training for NP students.
MeSH term(s)	COVID-19/epidemiology ; Humans ; Nurse Practitioners/education ; Simulation Training ; Students, Nursing/psychology ; Telemedicine ; Truth Disclosure
Language	English
Publishing date	2022-09-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	410686-6
ISSN	1938-2421 ; 0148-4834
ISSN (online)	1938-2421
ISSN	0148-4834
DOI	10.3928/01484834-20220705-08
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Article ; Online: Robotic ureteral reimplantation and uretero-ureterostomy treating the ureterovesical junction pathologies in children: technical considerations and preliminary results.

Mattioli, G / Lena, F / Fiorenza, V / Carlucci, Marcello

Journal of robotic surgery

2022 Volume 17, Issue 2, Page(s) 659–667

Abstract: Robot-assisted laparoscopic extravesical ureteral reimplantation (RALUR) and robotic ureteroureterostomy (RUU) are two mini-invasive surgical techniques that have begun to be performed in pediatric urology in recent years. RALUR has been employed ... ...

Abstract	Robot-assisted laparoscopic extravesical ureteral reimplantation (RALUR) and robotic ureteroureterostomy (RUU) are two mini-invasive surgical techniques that have begun to be performed in pediatric urology in recent years. RALUR has been employed especially for VUR treatment, while RUU is considered principally in case of complex doubled ureteral systems. Our aim is to discuss the safety and feasibility of these approaches in children, focusing on technical considerations and supporting their use in different anomalies and pathologies of the ureterovesical junction. We retrospectively collected data about 58 patients who underwent 44 dismembered RALUR (D-RALUR), 28 non-dismembered RALUR (ND-RALUR) and 5 RUU between May 2020 and December 2021. Indications for surgery were primary or secondary vesicoureteral reflux, megaureter, secondary UVJ obstructions, complicated doubled ureteral systems. Mean age was 3.5 years (range 0.6-12.9) and mean weight 17.1 (range 7.2-80). No intraoperative complications occurred nor conversion to open approach were reported. Major postoperative complications were reported in 11.7% of cases with a higher incidence for ND-RALUR. Mean hospital stay was 2.14 days (range 1-8). Success rate at the short-term follow-up was 91.9% for D-RALUR, 96.3% for ND-RALUR and 100% for RUU. RALUR and RUU are two feasible and safe procedures to perform in children. RALUR represents the most required and adequate technique in the treatment of UVJ pathologies, however, in selected cases RUU could represent an effective alternative that has to be considered.
MeSH term(s)	Humans ; Child ; Infant ; Child, Preschool ; Robotics ; Robotic Surgical Procedures/methods ; Retrospective Studies ; Ureterostomy ; Ureter/surgery ; Ureteral Obstruction/surgery ; Replantation/methods ; Laparoscopy/methods ; Treatment Outcome
Language	English
Publishing date	2022-10-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2268283-1
ISSN	1863-2491 ; 1863-2483
ISSN (online)	1863-2491
ISSN	1863-2483
DOI	10.1007/s11701-022-01478-7
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Article ; Online: An Innovative Virtual Poster Session for Doctor of Nursing Practice Student Project Presentations.

Diegel-Vacek, Lauren / Carlucci, Melisa

The Journal of nursing education

2020 Volume 59, Issue 12, Page(s) 697–700

Abstract: Background: The COVID-19 pandemic closed university campuses across the country. Nurse educators were challenged to develop innovative solutions for students to complete course requirements. The on-campus poster session used by a college of nursing as a ...

Abstract	Background: The COVID-19 pandemic closed university campuses across the country. Nurse educators were challenged to develop innovative solutions for students to complete course requirements. The on-campus poster session used by a college of nursing as a scholarly forum for dissemination of all Doctor of Nursing Practice (DNP) student final projects was cancelled due to the pandemic. Method: Nurse educators developed and implemented an interactive, synchronous virtual session using the Zoom Video Communications platform. Results: Twelve virtual sessions were held, and 73 students presented DNP project posters. More than 150 students and faculty attended the virtual poster sessions. Students and faculty had positive feedback regarding the virtual format. Student presentations were academically rigorous, and audiences engaged in robust discussion with DNP students. Conclusion: The virtual platform was successfully used for an interactive presentation by DNP student and nursing faculty participants. This format may be especially valuable for use of scholarship dissemination by distance learning programs. [J Nurs Educ. 2020;59(12):697-700.].
MeSH term(s)	Academic Dissertations as Topic ; COVID-19/epidemiology ; Education, Nursing, Graduate ; Humans ; Illinois/epidemiology ; Internet ; Nursing Research ; Pandemics ; Posters as Topic ; Videoconferencing
Language	English
Publishing date	2020-11-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	410686-6
ISSN	1938-2421 ; 0148-4834
ISSN (online)	1938-2421
ISSN	0148-4834
DOI	10.3928/01484834-20201118-07
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Article ; Online: Diurnal oscillations of MRI metrics in the brains of male participants.

Carlucci, Matthew / Lett, Tristram / Chavez, Sofia / Malinowski, Alexandra / Lobaugh, Nancy J / Petronis, Art

Nature communications

2023 Volume 14, Issue 1, Page(s) 7044

Abstract: Regulation of biological processes according to a 24-hr rhythm is essential for the normal functioning of an organism. Temporal variation in brain MRI data has often been attributed to circadian or diurnal oscillations; however, it is not clear if such ... ...

Abstract	Regulation of biological processes according to a 24-hr rhythm is essential for the normal functioning of an organism. Temporal variation in brain MRI data has often been attributed to circadian or diurnal oscillations; however, it is not clear if such oscillations exist. Here, we provide evidence that diurnal oscillations indeed govern multiple MRI metrics. We recorded cerebral blood flow, diffusion-tensor metrics, T1 relaxation, and cortical structural features every three hours over a 24-hr period in each of 16 adult male controls and eight adult male participants with bipolar disorder. Diurnal oscillations are detected in numerous MRI metrics at the whole-brain level, and regionally. Rhythmicity parameters in the participants with bipolar disorder are similar to the controls for most metrics, except for a larger phase variation in cerebral blood flow. The ubiquitous nature of diurnal oscillations has broad implications for neuroimaging studies and furthers our understanding of the dynamic nature of the human brain.
MeSH term(s)	Adult ; Humans ; Male ; Circadian Rhythm/physiology ; Brain/diagnostic imaging ; Magnetic Resonance Imaging ; Bipolar Disorder ; Neuroimaging
Language	English
Publishing date	2023-11-03
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-023-42588-6
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Article ; Online: Scikick: A sidekick for workflow clarity and reproducibility during extensive data analysis.

Carlucci, Matthew / Bareikis, Tadas / Koncevičius, Karolis / Gibas, Povilas / Kriščiūnas, Algimantas / Petronis, Art / Oh, Gabriel

PloS one

2023 Volume 18, Issue 7, Page(s) e0289171

Abstract: Reproducibility is crucial for scientific progress, yet a clear research data analysis workflow is challenging to implement and maintain. As a result, a record of computational steps performed on the data to arrive at the key research findings is often ... ...

Abstract	Reproducibility is crucial for scientific progress, yet a clear research data analysis workflow is challenging to implement and maintain. As a result, a record of computational steps performed on the data to arrive at the key research findings is often missing. We developed Scikick, a tool that eases the configuration, execution, and presentation of scientific computational analyses. Scikick allows for workflow configurations with notebooks as the units of execution, defines a standard structure for the project, automatically tracks the defined interdependencies between the data analysis steps, and implements methods to compile all research results into a cohesive final report. Utilities provided by Scikick help turn the complicated management of transparent data analysis workflows into a standardized and feasible practice. Scikick version 0.2.1 code and documentation is available as supplementary material. The Scikick software is available on GitHub (https://github.com/matthewcarlucci/scikick) and is distributed with PyPi (https://pypi.org/project/scikick/) under a GPL-3 license.
MeSH term(s)	Computational Biology/methods ; Workflow ; Reproducibility of Results ; Software ; Data Analysis
Language	English
Publishing date	2023-07-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0289171
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Article: First report of

Habib, Wassim / Carlucci, Mariangela / Manco, Lorenzo / Altamura, Giuseppe / Delle Donne, Angelo Giovanni / Nigro, Franco

Plant disease

2023

Abstract: Common fig (Ficus carica L.) in is one of the most important crops in the Mediterranean area. In Italy, it is grown on a total area of 2118 ha. In Apulia (South-eastern Italy), the annual production of fig exceeds 3200 tons annually and together with ... ...

Abstract	Common fig (Ficus carica L.) in is one of the most important crops in the Mediterranean area. In Italy, it is grown on a total area of 2118 ha. In Apulia (South-eastern Italy), the annual production of fig exceeds 3200 tons annually and together with olive and grapevine, they characterize the Apulian agricultural panorama. In September 2021, symptoms of a vascular wilt disease and, in severe cases, decline tree mortality were observed in Salento area (Apulia). Symptomatic Affected plants showed symptoms of leaf wilt and different stages of disease expression, which begins with leaf chlorosis on shoots, followed by wilting, extensive defoliation and twig dieback. On the main branches andlower part of the trunk and in some cases on lateral branches, bark cracks and cankers were observed and extended wood discoloration was detected in cross sections. In two orchards located in Salice Salentino (Site 1) and Squinzano (Site 2), where disease incidence exceeded 80%, 3-5 wood discs per tree were gathered from affected tissues from two (Site 1) and four (Site 2) trees. Isolations were performed on malt extract agar 2% amended with 0.5 g L-1 streptomycin sulfate. A Ceratocystis species was recovered from all samples trees with high frequencies (83.3%). Two-week-old colonies on potato dextrose agar showed black ascomata with 300-600 µm wide bases and 1100-2250 µm long necks. On the tips of the necks, ascospores (5-6x4-5 µm) exuded in creamy white sticky masses. Endoconidia (5-9x4.5-7 µm) were abundant, cylindrical, aseptate, and produced in chains. Two monoconidial representative strains CRSFA.Cer.033 (Site 1) and CRSFA.Cer.035 (Site 2) were deposited in the DISSPA Di.S.S.P.A. collection of the University of Bari. Species identification was done through sequence analyses of rDNA internal transcribed spacer region (ITS) using ITS5/ITS4 primers (White et al. 1990), elongation factor 1 alpha gene (TEF) using EF1/EF2 (O'Donnell et al. 1998) and RNA polymerase II gene (RPB2) gene using RPB2-5F/FRPB2fRPB2-7cR (Liu et al. 1999). Sequences were deposited in NCBI GenBank (accession numbers: OQ329983-OQ335969 (ITS), OQ352265-OQ352266 (TEF), OQ352268-OQ352267 (RPB2)). The sequences of both Apulian isolates were identical. BLAST searches revealed high similarity to the sequences of two isolates of Ceratocystis ficicola Kajitani and Masuya from Japan: ex-type CMW38543 and CMW38544, specifically 98.41% identity matching with KY685076 (ITS), 100% with KY685079 (TEF), and 99.87% with KY685083 and KY685082 (RPB2). Pathogenicity tests were conducted, on six common fig 'Dottato' seedlings by inoculating one year-old twigs with mycelium plugs (Bolboli et al. 2022). Control plants were inoculated with PDA plugs without mycelium. After one month, all inoculated twigs showed symptoms of wilt. Forty days post-inoculation, the bark of inoculated twigs was removed, and longitudinal and transverse sections revealed wood discolorations extending above and below the inoculation point. Ceratocystis ficicola was consistently reisolated from symptomatic tissues and identified as described above, thus fulfilling Koch's postulates. Neither symptoms nor positive isolations were observed in control seedlings. The pathogen was first described in 2011 in Japan (Kajitani and Masuya, 2011) where it currently affects all fig-producing areas. In 2018, it was reported for the first time in the EPPO region in Greece (Tsopelas et al., 2021), and to our knowledge, this is the first report on its detection in Italy. Since February 2022, C. ficicola has been included in the EPPO alert list because of its potential to cause tree mortality and the difficulty of its eradication. Regional national surveys are therefore urgently needed to determine its distribution in the fig growing areas of Italy and limit its spread. References Bolboli, Z., et al. 2022. Mycol. Prog. 21:89. doi: 10.1007/s11557-022-01834-9 Kajitani, Y., and Masuya, H., 2011. Mycoscience 52:349. doi: 10.1007/s10267-011-0116-5 Liu, Y. J., et al. 1999. Mol. Biol. and Evol. 16:1799. doi: 10.1093/oxfordjournals.molbev.a026092 O'Donnell, K., et al. 1998. Proc Natl Acad Sci USA 95:2044. doi: 10.1073/pnas.95.5.2044 Tsopelas, P., et al. 2021. Phytopathol. Mediterr. 60:337. doi: 10.36253/phyto-12794 White, T. J., et al. 1990. Page 315 in: PCR Protocols: A Guide to Methods and Applications. Academic Press, San Diego. doi: 10.1016/0307-4412(91)90165-5.
Language	English
Publishing date	2023-07-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	754182-x
ISSN	0191-2917
ISSN	0191-2917
DOI	10.1094/PDIS-03-23-0464-PDN
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