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  1. AU="Carmen Gonzalez"
  2. AU="Cheah, Jaime H"
  3. AU="Forte, Florence"
  4. AU="Anika Nier"
  5. AU="Bar, Adi"
  6. AU="Alvarado Pinedo, María F."
  7. AU="Scarlett, Garry"
  8. AU="Carlos G. Vanoye"
  9. AU=Lohrmann Jens
  10. AU="Petersen, Moritz"
  11. AU="Giovanni, L."
  12. AU="Liu, Xingzheng"
  13. AU="Głód, Mateusz"
  14. AU=Teo Kelvin Yi Chong
  15. AU="Khatmi, Aysan"
  16. AU="Erculiani, M"
  17. AU="Olivier Lortholary"
  18. AU="Lisnic, Vanda Juranic"
  19. AU="Seabloom, Eric W"
  20. AU="Odvina, Clarita V"
  21. AU="Singh, Inderbir"
  22. AU="Wonoh Lee"
  23. AU="Nelson, Warrick"
  24. AU="Douglas, David N"
  25. AU="King, Gary"
  26. AU="Barbera, Lauren"
  27. AU="Carlino, Antonio"
  28. AU="Shan, Qing-Hua"
  29. AU="Starko, S"
  30. AU="Lievre, Loïc"
  31. AU=Cammack N
  32. AU="Xia, Qin"
  33. AU="Ong, Ju Lynn"
  34. AU="Cullin, Christophe"
  35. AU="Georg K.S. Andersson"
  36. AU="Jeannel, Gaël-François"
  37. AU="Stuart Woods"
  38. AU="Shchegolev, A."
  39. AU="Nadeau, Pierre-Louis"
  40. AU="Gordon, David E A"
  41. AU="Shahid Mahmood"
  42. AU="Rosenblatt, Karin"
  43. AU="Dasgupta, Suvankar"
  44. AU=Nguyen Sylvain AU=Nguyen Sylvain

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  1. Artikel ; Online: Nanoplastics Increase Fish Susceptibility to Nodavirus Infection and Reduce Antiviral Immune Responses

    Carmen González-Fernández / Alberto Cuesta

    International Journal of Molecular Sciences, Vol 23, Iss 1483, p

    2022  Band 1483

    Abstract: Nanoplastics (NPs) might cause different negative effects on aquatic organisms at different biological levels, ranging from single cells to whole organisms, including cytotoxicity, reproduction, behavior or oxidative stress. However, the impact of NPs on ...

    Abstract Nanoplastics (NPs) might cause different negative effects on aquatic organisms at different biological levels, ranging from single cells to whole organisms, including cytotoxicity, reproduction, behavior or oxidative stress. However, the impact of NPs on disease resistance is almost unknown. The objective of this study was to assess whether exposure to 50 nm functionalized polystyrene NPs impacts fish susceptibility to viral diseases both in vitro and in vivo . In particular, we focused on the nervous necrosis virus (NNV), which affects many fish species, producing viral encephalopathy and retinopathy (VER), and causes great economic losses in marine aquaculture. In vitro and in vivo approaches were used. A brain cell line (SaB-1) was exposed to 1 μg mL −1 of functionalized polystyrene NPs (PS-NH 2 , PS-COOH) and then infected with NNV. Viral titers were increased in NP-exposed cells whilst the transcription of inflammatory and antiviral markers was lowered when compared to those cells only infected with NNV. In addition, European sea bass ( Dicentrarchus labrax ) juveniles were intraperitoneally injected with the same NPs and then challenged with NNV. Our results indicated that NPs increased the viral replication and clinical signs under which the fish died although the cumulate mortality was unaltered. Again, exposure to NPs produced a lowered inflammatory and antiviral response. Our results highlight that the presence of NPs might impact the infection process of NNV and fish resistance to the disease, posing an additional risk to marine organisms.
    Schlagwörter nanoplastics ; fish ; European sea bass ; antiviral ; nodavirus (NNV) ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Thema/Rubrik (Code) 333
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Homenaje a Roque Dalton en el LXXXV aniversario de su nacimiento y XLV aniversario de su asesinato

    Carmen González Huguet

    Realidad, Iss

    2020  Band 156

    Abstract: No hay resúmenes disponibles Realidad: Revista de Ciencias Sociales y Humanidades No. 156, 2020: 209- ... ...

    Abstract No hay resúmenes disponibles Realidad: Revista de Ciencias Sociales y Humanidades No. 156, 2020: 209-241
    Schlagwörter Dalton García ; Roque Antonio ; 1935-1975-Crítica e interpretación ; Pensamiento político y social ; Poesía salvadoreña ; Social sciences (General) ; H1-99
    Sprache Spanisch
    Erscheinungsdatum 2020-12-01T00:00:00Z
    Verlag Universidad Centroamericana José Simeón Cañas
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Use of Double Gelled Microspheres to Improve Release Control of Cinnamon-Loaded Nanoemulsions

    Esther Santamaría / Alicia Maestro / Carmen González

    Molecules, Vol 29, Iss 1, p

    2023  Band 158

    Abstract: The use of nanoemulsions as encapsulation systems for active ingredients, such as cinnamon oil, has been studied. A surfactant based on polyoxyethylene glycerol esters from coconut/palm kernel oil has been used. The nanoemulsions were obtained by the two ...

    Abstract The use of nanoemulsions as encapsulation systems for active ingredients, such as cinnamon oil, has been studied. A surfactant based on polyoxyethylene glycerol esters from coconut/palm kernel oil has been used. The nanoemulsions were obtained by the two most commonly low-energy emulsification methods, the composition inversion phase (PIC) and the temperature inversion phase (PIT) methods. Nanoemulsions were successfully obtained by both methods, with very small droplet sizes (5–14 nm) in both cases, but a greater stability was observed when the PIT method was used. Nanoemulsions were encapsulated by external gelation using two different polysaccharides, alginate or chitosan, dissolved in the continuous phase of the nanoemulsion. Then, the nanoemulsion was dropped into a bath with a gelling agent. To improve the release control of cinnamon oil and avoid the burst effect, beads prepared with one of the polysaccharides were coated with the second polysaccharide and then gelled again. Double gelled beads were successfully obtained, the core with chitosan and the outer layer (shell) with alginate. SEM images showed the morphology of the single beads presenting high porosity. When the beads were coated, the porosity decreased because the second polysaccharide molecules covered the pre-existing pores. The smoother surface was obtained when this second layer was, in turn, gelled. The release patterns at pH = 2 and pH = 7 were studied. It was observed that the double gelled bead provided a more gradual release, but maintained approximately the same amount of final released oil. The release patterns were fitted to the Korsmeyer-Peppas model. The fitting parameters reflected the effect of the different coating layers, correlating with different diffusion mechanisms according to the bead core and shell materials.
    Schlagwörter encapsulation ; double gelled microspheres ; nanoemulsions ; cinnamon oil ; low-energy emulsification method ; alginate ; Organic chemistry ; QD241-441
    Thema/Rubrik (Code) 540
    Sprache Englisch
    Erscheinungsdatum 2023-12-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Neuropeptide Y: Direct vasoconstrictor and facilitatory effects on P2X1 receptor-dependent vasoconstriction in human small abdominal arteries.

    Del Carmen Gonzalez-Montelongo, Maria / Meades, Jessica Lauren / Fortuny-Gomez, Anna / Fountain, Samuel J

    Vascular pharmacology

    2023  Band 151, Seite(n) 107192

    Abstract: Neuropeptide Y (NPY) is co-released with norepinephrine and ATP by sympathetic nerves innervating arteries. Circulating NPY is elevated during exercise and cardiovascular disease, though information regarding the vasomotor function of NPY in human blood ... ...

    Abstract Neuropeptide Y (NPY) is co-released with norepinephrine and ATP by sympathetic nerves innervating arteries. Circulating NPY is elevated during exercise and cardiovascular disease, though information regarding the vasomotor function of NPY in human blood vessels is limited. Wire myography revealed NPY directly stimulated vasoconstriction (EC
    Mesh-Begriff(e) Humans ; Neuropeptide Y/pharmacology ; Vasoconstriction ; Vasoconstrictor Agents/pharmacology ; Receptors, Purinergic P2X1 ; Receptors, Neuropeptide Y/metabolism ; Arteries/metabolism
    Chemische Substanzen Neuropeptide Y ; Vasoconstrictor Agents ; Receptors, Purinergic P2X1 ; Receptors, Neuropeptide Y
    Sprache Englisch
    Erscheinungsdatum 2023-07-05
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2082846-9
    ISSN 1879-3649 ; 1537-1891 ; 1879-3649
    ISSN (online) 1879-3649 ; 1537-1891
    ISSN 1879-3649
    DOI 10.1016/j.vph.2023.107192
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Control of Redox Homeostasis by Short-Chain Fatty Acids

    Carmen González-Bosch / Patricia A. Zunszain / Giovanni E. Mann

    Pathogens, Vol 12, Iss 486, p

    Implications for the Prevention and Treatment of Breast Cancer

    2023  Band 486

    Abstract: Breast cancer is the leading cause of death among women worldwide, and certain subtypes are highly aggressive and drug resistant. As oxidative stress is linked to the onset and progression of cancer, new alternative therapies, based on plant-derived ... ...

    Abstract Breast cancer is the leading cause of death among women worldwide, and certain subtypes are highly aggressive and drug resistant. As oxidative stress is linked to the onset and progression of cancer, new alternative therapies, based on plant-derived compounds that activate signaling pathways involved in the maintenance of cellular redox homeostasis, have received increasing interest. Among the bioactive dietary compounds considered for cancer prevention and treatment are flavonoids, such as quercetin, carotenoids, such as lycopene, polyphenols, such as resveratrol and stilbenes, and isothiocyanates, such as sulforaphane. In healthy cells, these bioactive phytochemicals exhibit antioxidant, anti-apoptotic and anti-inflammatory properties through intracellular signaling pathways and epigenetic regulation. Short-chain fatty acids (SCFAs), produced by intestinal microbiota and obtained from the diet, also exhibit anti-inflammatory and anti-proliferative properties related to their redox signaling activity—and are thus key for cell homeostasis. There is evidence supporting an antioxidant role for SCFAs, mainly butyrate, as modulators of Nrf2-Keap1 signaling involving the inhibition of histone deacetylases (HDACs) and/or Nrf2 nuclear translocation. Incorporation of SCFAs in nutritional and pharmacological interventions changes the composition of the the intestinal microbiota, which has been shown to be relevant for cancer prevention and treatment. In this review, we focused on the antioxidant properties of SCFAs and their impact on cancer development and treatment, with special emphasis on breast cancer.
    Schlagwörter breast cancer ; short-chain fatty acids ; butyrate ; microbiota ; redox signaling ; Keap1-Nrf2 ; Medicine ; R
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2023-03-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Magnetic Iron Nanoparticles

    Jesús Roberto Vargas-Ortiz / Carmen Gonzalez / Karen Esquivel

    Processes, Vol 10, Iss 2282, p

    Synthesis, Surface Enhancements, and Biological Challenges

    2022  Band 2282

    Abstract: This review focuses on the role of magnetic nanoparticles (MNPs), their physicochemical properties, their potential applications, and their association with the consequent toxicological effects in complex biologic systems. These MNPs have generated an ... ...

    Abstract This review focuses on the role of magnetic nanoparticles (MNPs), their physicochemical properties, their potential applications, and their association with the consequent toxicological effects in complex biologic systems. These MNPs have generated an accelerated development and research movement in the last two decades. They are solving a large portion of problems in several industries, including cosmetics, pharmaceuticals, diagnostics, water remediation, photoelectronics, and information storage, to name a few. As a result, more MNPs are put into contact with biological organisms, including humans, via interacting with their cellular structures. This situation will require a deeper understanding of these particles’ full impact in interacting with complex biological systems, and even though extensive studies have been carried out on different biological systems discussing toxicology aspects of MNP systems used in biomedical applications, they give mixed and inconclusive results. Chemical agencies, such as the Registration, Evaluation, Authorization, and Restriction of Chemical substances (REACH) legislation for registration, evaluation, and authorization of substances and materials from the European Chemical Agency (ECHA), have held meetings to discuss the issue. However, nanomaterials (NMs) are being categorized by composition alone, ignoring the physicochemical properties and possible risks that their size, stability, crystallinity, and morphology could bring to health. Although several initiatives are being discussed around the world for the correct management and disposal of these materials, thanks to the extensive work of researchers everywhere addressing the issue of related biological impacts and concerns, and a new nanoethics and nanosafety branch to help clarify and bring together information about the impact of nanoparticles, more questions than answers have arisen regarding the behavior of MNPs with a wide range of effects in the same tissue. The generation of a consolidative framework of these ...
    Schlagwörter iron oxide ; magnetic nanoparticles ; nanomaterials ; nanoparticles ; nanotoxicology ; Chemical technology ; TP1-1185 ; Chemistry ; QD1-999
    Thema/Rubrik (Code) 620
    Sprache Englisch
    Erscheinungsdatum 2022-11-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: Vida y obra del Hno. Alain (Henri Eugene Liogier y Allut) en Cuba / Life and work of Bro. Alain (Henri Eugene Liogier y Allut) in Cuba

    Carmen González García

    Revista del Jardín Botánico Nacional, Vol 39, Iss 0, Pp 113-

    2018  Band 123

    Abstract: RESUMEN En este trabajo se presenta una síntesis de la vida y obra de Henri Eugene Liogier de Sereys Allut (Hno. Alain). Se destaca su labor durante los 27 años que permaneció en Cuba, donde alternó su vocación como eclesiástico y docente en el Colegio ... ...

    Abstract RESUMEN En este trabajo se presenta una síntesis de la vida y obra de Henri Eugene Liogier de Sereys Allut (Hno. Alain). Se destaca su labor durante los 27 años que permaneció en Cuba, donde alternó su vocación como eclesiástico y docente en el Colegio de La Salle del Vedado (La Habana) y su amor por la naturaleza vegetal cubana, guiado por las enseñanzas y conocimientos de los Hnos. León y Marie-Victorin. El Hno. Alain realizó diferentes expediciones botánicas a lo largo de la isla, recolectó plantas y realizó observaciones ecológicas en muchas de las localidades visitadas. Sus contribuciones al estudio de la flora de Cuba incluyen más de 170 nombres científicos de plantas propuestas por él, además de su importante bibliografía de diversas temáticas y que junto con el Hno. León colaboró en los estudios y redacción de la Flora de Cuba, obra monumental de la botánica sistemática cubana. Palabras clave: personalidades botánicas, Hermanos de La Salle, flora cubana ABSTRACT A synthesis of the life and work of Henri Eugene Liogier de Sereys Allut (Bro. Alain) is presented. His work is outstanding during the 27 years he spent in Cuba, where he alternated his vocation as an ecclesiastic and teacher in the College of La Salle of Vedado (Havana) and his love of Cuban plants nature, guided by the teachings and knowledge of the Bros. León and Marie-Victorin. The Bro. Alain carried out different botanical expeditions throughout the island collecting plants and making ecological observations in many of the localities visited. His contributions to the study of Cuban flora covered more than 170 scientific names of plants proposed by him, as well as his important bibliography on various topics and that together with Bro. Leon collaborated in the studies and writing of the Flora de Cuba, a monumental work of Cuban botany. Keywords: botany personalities, Brothers of La Salle, Cuban flora Recibido: mayo 2018 Aceptado: julio 2018 Publicado online 30 de diciembre de 2018. ISSN 2410-5546 RNPS 2372 (DIGITAL) - ISSN 0253-5696 RNPS 0060 ...
    Schlagwörter personalidades botánicas ; hermanos de la salle ; flora cubana ; Plant ecology ; QK900-989
    Sprache Englisch
    Erscheinungsdatum 2018-08-01T00:00:00Z
    Verlag Universidad de La Habana
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Non- Saccharomyces as Biotools to Control the Production of Off-Flavors in Wines

    Antonio Morata / Iris Loira / Carmen González / Carlos Escott

    Molecules, Vol 26, Iss 4571, p

    2021  Band 4571

    Abstract: Off-flavors produced by undesirable microbial spoilage are a major concern in wineries, as they affect wine quality. This situation is worse in warm areas affected by global warming because of the resulting higher pHs in wines. Natural biotechnologies ... ...

    Abstract Off-flavors produced by undesirable microbial spoilage are a major concern in wineries, as they affect wine quality. This situation is worse in warm areas affected by global warming because of the resulting higher pHs in wines. Natural biotechnologies can aid in effectively controlling these processes, while reducing the use of chemical preservatives such as SO 2 . Bioacidification reduces the development of spoilage yeasts and bacteria, but also increases the amount of molecular SO 2 , which allows for lower total levels. The use of non- Saccharomyces yeasts, such as Lachancea thermotolerans , results in effective acidification through the production of lactic acid from sugars. Furthermore, high lactic acid contents (>4 g/L) inhibit lactic acid bacteria and have some effect on Brettanomyces . Additionally, the use of yeasts with hydroxycinnamate decarboxylase (HCDC) activity can be useful to promote the fermentative formation of stable vinylphenolic pyranoanthocyanins, reducing the amount of ethylphenol precursors. This biotechnology increases the amount of stable pigments and simultaneously prevents the formation of high contents of ethylphenols, even when the wine is contaminated by Brettanomyces .
    Schlagwörter wine ; yeasts ; non- Saccharomyces ; off-smells ; volatile acidity ; ethylphenols ; Organic chemistry ; QD241-441
    Sprache Englisch
    Erscheinungsdatum 2021-07-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: José Blain, un modesto naturalista

    Carmen González García

    Revista del Jardín Botánico Nacional, Vol 38, Iss 1, Pp 167-

    su presencia en la botánica cubana / José Blain, a modest naturalist: his presence in the Cuban botany

    2017  Band 173

    Abstract: RESUMEN A través de la historia, cubanos y extranjeros han dedicado su obra al conocimiento y desarrollo de la botánica en Cuba, y han dado a conocer al mundo las bondades y riquezas de la naturaleza cubana, en especial de su flora, por lo que han ... ...

    Abstract RESUMEN A través de la historia, cubanos y extranjeros han dedicado su obra al conocimiento y desarrollo de la botánica en Cuba, y han dado a conocer al mundo las bondades y riquezas de la naturaleza cubana, en especial de su flora, por lo que han merecido respeto y reconocimiento. En la botánica cubana del siglo XIX, fundamentalmente en su segunda mitad, se destacó José Blain. En el presente trabajo se argumenta su presencia y legado para las ciencias naturales en Cuba, en particular, para la botánica. Se dan a conocer sus aportes al estudio de las plantas, sus cualidades como naturalista empírico y sus relaciones con diferentes científicos de la época, los cuales reconocieron su loable trabajo, colaboraron y compartieron amistad. Blain recibió el reconocimiento de sus colegas y en su honor fueron nombradas nuevas especies para la ciencia. De este modo, José Blain tiene el reconocido prestigio para la botánica cubana, coleccionista y amante de la naturaleza. Palabras clave: finca “El Retiro”, jardines botánicos, localidad “Aspiro”, personalidades botánicas ABSTRACT Through the history, Cubans and foreigners have dedicated their work to the knowledge and develoment of botany in Cuba, and have made known to the world the benefits and riches of Cuban nature, especially its flora, for what they have deserved respect and recognition. In the Cuban botany of the nineteenth century, mainly in the second half, stood out José Blain. In the present work his presence and legacy for the natural sciences in Cuba, in particular, for the botany, is argued. His contributions to the study of plants, his qualities as an empirical naturalist and his relationships with different scientists of the time, are acknowledged, who recognized his praiseworthy work, collaborated and shared friendship. Blain received recognition from his colleagues and in his honor were named new species for science. In this way, José Blain has the recognized prestige for the Cuban botany, collector and lover of nature. Keywords: Aspiro, “El Retiro”, ...
    Schlagwörter Plant ecology ; QK900-989
    Sprache Englisch
    Erscheinungsdatum 2017-11-01T00:00:00Z
    Verlag Universidad de La Habana
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: Educación de calidad y reconstrucción resiliente en el alumnado. Estudio piloto durante el confinamiento por la Covid-19

    Raquel Artuch Garde / María Carmen González-Torres

    DEDiCA, Iss

    2021  Band 18

    Abstract: Se plantea una investigación que tiene como objetivo evaluar la resiliencia de un grupo de 103 alumnos y alumnas de primaria y secundaria, a través de una encuesta online para conocer su percepción general y establecer las diferencias en función de la ... ...

    Abstract Se plantea una investigación que tiene como objetivo evaluar la resiliencia de un grupo de 103 alumnos y alumnas de primaria y secundaria, a través de una encuesta online para conocer su percepción general y establecer las diferencias en función de la etapa educativa. El estudio se llevó a cabo en el mes de junio de 2020 cuando todavía todos estaban confinados en sus casas. Entre los resultados se destaca la importancia de trabajar con todos ellos la comunicación emocional con las familias, sentirse partes del centro educativo, desarrollar habilidades y destrezas y fomentar el conocimiento de sus fortalezas. Se encuentran pocas diferencias significativas entre estas edades (10-15 años) y se propone tener en cuenta el modelo de Henderson y Milstein para desarrollar la resiliencia en el ámbito educativo.
    Schlagwörter alumnado de primaria y secundaria ; calidad educativa ; fortalezas ; participación ; resiliencia ; Education (General) ; L7-991 ; History of scholarship and learning. The humanities ; AZ20-999
    Sprache Englisch
    Erscheinungsdatum 2021-05-01T00:00:00Z
    Verlag Universidad de Granada
    Dokumenttyp Artikel ; Online
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