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  1. Article ; Online: Antioxidant Activity of Polyphenols, from

    Bensaada, Hichem / Soto-Garcia, María Fernanda / Carmona-Hernandez, Juan Carlos

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 10

    Abstract: Plant polyphenols offer several benefits for the prevention of diverse illnesses. Fruit's edible and inedible parts (pulp, seeds, peels, stems, flowers) are important sources of polyphenols. Different industrial processes for fruit treatment and ... ...

    Abstract Plant polyphenols offer several benefits for the prevention of diverse illnesses. Fruit's edible and inedible parts (pulp, seeds, peels, stems, flowers) are important sources of polyphenols. Different industrial processes for fruit treatment and commercialization affect the total polyphenol content (TPC), and probably the biological activity. The purpose of the present work was to determine the TPC and antioxidant activity (by DPPH) of polyphenols extracted from the pulp and seeds of
    MeSH term(s) Antioxidants/chemistry ; Arecaceae/chemistry ; Dehydration ; Fruit/chemistry ; Polyphenols/chemistry
    Chemical Substances Antioxidants ; Polyphenols
    Language English
    Publishing date 2022-05-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27103065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Potential Hypoglycemic and Antilipidemic Activity of Polyphenols from

    Angel-Isaza, Jaime / Carmona-Hernandez, Juan Carlos / González-Correa, Clara Helena / Narváez-Solarte, William Vicente

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 8

    Abstract: The consumption of fruits or by-products from plants of the Passifloraceae family has been associated with multiple health and nutritional benefits, due to their phenolic compound content. Likewise, the effects of polyphenols ... ...

    Abstract The consumption of fruits or by-products from plants of the Passifloraceae family has been associated with multiple health and nutritional benefits, due to their phenolic compound content. Likewise, the effects of polyphenols from
    MeSH term(s) Rats ; Mice ; Animals ; Polyphenols/pharmacology ; Passiflora ; Hypoglycemic Agents/pharmacology ; Metabolic Syndrome/drug therapy ; Rats, Wistar ; Camellia sinensis ; Tea ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use
    Chemical Substances Polyphenols ; Hypoglycemic Agents ; Tea ; Plant Extracts
    Language English
    Publishing date 2023-04-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28083551
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Polyphenols from Passiflora ligularis Regulate Inflammatory Markers and Weight Gain

    Angel-Isaza Jaime / Carmona-Hernandez Juan Carlos / Narváez-Solarte William / Gonzalez-Correa Clara Helena

    Biomolecular Concepts, Vol 12, Iss 1, Pp 36-

    2021  Volume 45

    Abstract: Weight-related disorders affect more than half of the adult population worldwide; they are also concomitant with a state of chronic low-grade inflammation manifesting in abnormal cytokine production. The present study evaluated the effect of polyphenol ... ...

    Abstract Weight-related disorders affect more than half of the adult population worldwide; they are also concomitant with a state of chronic low-grade inflammation manifesting in abnormal cytokine production. The present study evaluated the effect of polyphenol and flavonoid extract from Passiflora ligularis (granadilla) on low-grade inflammation and body weight in overweight Wistar rats. To induce weight-gain, rats were fed a chow diet with 30% sucrose water and supplemented with 2.0, 2.5, and 3.0 g/L polyphenol extracts (n = 16). The design was a 3 +1 factorial model performed for 42 days (granadilla polyphenols, 3 levels of supplementation, and 1 control group). In addition to total polyphenol and total flavonoid content, the major identified and quantified polyphenol, via UHPLC, was ferulic acid. Interleukin 6 (IL-6), and cytokine tumor necrosis factor-alpha (TNF-α) were evaluated in serum. A decline in the concentration of TNF-α and in weight-gain was found in P. ligularis (granadilla) groups treated with the 2.5 g/L dose. Consumption of polyphenol extracts from granadilla inhibits interleukin-activity as an indicator of inflammation and aids in body-weight control, considering similar food intake, in overweight Wistar rats.
    Keywords passiflora ligularis (granadilla) ; phenolic compounds ; anti-inflammatory activity ; overweight rats ; Biology (General) ; QH301-705.5
    Subject code 630
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher De Gruyter
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Flavonoid/Polyphenol Ratio in

    Carmona-Hernandez, Juan Carlos / Le, Mai / Idárraga-Mejía, Ana María / González-Correa, Clara Helena

    Molecules (Basel, Switzerland)

    2021  Volume 26, Issue 21

    Abstract: Studies on polyphenols and flavonoids in natural products reveal benefits in the prevention of multiple diseases. Proper extraction, treatment of extracts, and quantification of polyphenols and flavonoids demand attention from the scientific community in ...

    Abstract Studies on polyphenols and flavonoids in natural products reveal benefits in the prevention of multiple diseases. Proper extraction, treatment of extracts, and quantification of polyphenols and flavonoids demand attention from the scientific community in order to report more specific biological action. Total polyphenol content (TPC) and total flavonoid content (TFC) (measured at three different times) of ethanol, methanol and acetone extracts of
    MeSH term(s) Antioxidants/analysis ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Cacao/chemistry ; Chromatography, High Pressure Liquid ; Flavonoids/chemistry ; Flavonoids/pharmacology ; Fruit/chemistry ; Phytochemicals ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Polyphenols/chemistry ; Polyphenols/pharmacology ; Solvents ; Spectrum Analysis
    Chemical Substances Antioxidants ; Flavonoids ; Phytochemicals ; Plant Extracts ; Polyphenols ; Solvents
    Language English
    Publishing date 2021-10-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules26216431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Polyphenols from Passiflora ligularis Regulate Inflammatory Markers and Weight Gain.

    Angel-Isaza, Jaime / Carmona-Hernandez, Juan Carlos / Narváez-Solarte, William / Gonzalez-Correa, Clara Helena

    Biomolecular concepts

    2021  Volume 12, Issue 1, Page(s) 36–45

    Abstract: Weight-related disorders affect more than half of the adult population worldwide; they are also concomitant with a state of chronic low-grade inflammation manifesting in abnormal cytokine production. The present study evaluated the effect of polyphenol ... ...

    Abstract Weight-related disorders affect more than half of the adult population worldwide; they are also concomitant with a state of chronic low-grade inflammation manifesting in abnormal cytokine production. The present study evaluated the effect of polyphenol and flavonoid extract from
    MeSH term(s) Animals ; Biomarkers/metabolism ; Dietary Supplements ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/pathology ; Male ; Passiflora/chemistry ; Plant Extracts/pharmacology ; Polyphenols/pharmacology ; Rats ; Rats, Wistar ; Weight Gain
    Chemical Substances Biomarkers ; Plant Extracts ; Polyphenols
    Language English
    Publishing date 2021-06-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2557908-3
    ISSN 1868-503X ; 1868-5021
    ISSN (online) 1868-503X
    ISSN 1868-5021
    DOI 10.1515/bmc-2021-0005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effect of 8-Week Consumption of a Dietary Pattern Based on Fruit, Avocado, Whole Grains, and Trout on Postprandial Inflammatory and Oxidative Stress Gene Expression in Obese People.

    Muñoz-Pérez, Diana María / González-Correa, Clara Helena / Astudillo Muñoz, Elcy Yaned / Sánchez-Giraldo, Maite / Carmona-Hernández, Juan Carlos / López-Miranda, José / Camargo, Antonio / Rangel-Zúñiga, Oriol Alberto

    Nutrients

    2023  Volume 15, Issue 2

    Abstract: Overweight and obesity constitute a major global public health problem. Healthy dietary patterns induce changes at the molecular level. Currently, there are no studies evaluating the effect of a diet based on fruit, avocado, whole grains, and trout ( ... ...

    Abstract Overweight and obesity constitute a major global public health problem. Healthy dietary patterns induce changes at the molecular level. Currently, there are no studies evaluating the effect of a diet based on fruit, avocado, whole grains, and trout (FAWGT diet) on the expression of obesity-related genes. This randomized controlled crossover study included 44 obese Colombians with BMI ≥30 kg/m
    MeSH term(s) Animals ; Cross-Over Studies ; Fruit ; Gene Expression ; Inflammation/diet therapy ; Inflammation/genetics ; Inflammation/metabolism ; Obesity/diet therapy ; Obesity/genetics ; Obesity/metabolism ; Oxidative Stress ; Persea ; Trout ; Whole Grains ; Humans ; Fish Proteins, Dietary
    Chemical Substances Fish Proteins, Dietary
    Language English
    Publishing date 2023-01-07
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15020306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Polyphenol Extracts from Three Colombian Passifloras (Passion Fruits) Prevent Inflammation-Induced Barrier Dysfunction of Caco-2 Cells.

    Carmona-Hernandez, Juan Carlos / Taborda-Ocampo, Gonzalo / Valdez, Jonathan C / Bolling, Bradley W / González-Correa, Clara Helena

    Molecules (Basel, Switzerland)

    2019  Volume 24, Issue 24

    Abstract: Chronic intestinal inflammation is associated with pathophysiology of obesity and inflammatory bowel diseases. Gastrointestinal inflammation increases barrier dysfunction exacerbating the immune response and perpetuating chronic inflammation. Anti- ... ...

    Abstract Chronic intestinal inflammation is associated with pathophysiology of obesity and inflammatory bowel diseases. Gastrointestinal inflammation increases barrier dysfunction exacerbating the immune response and perpetuating chronic inflammation. Anti-inflammatory flavonoids may prevent this intestinal barrier dysfunction. The purpose of this study was to evaluate the polyphenol composition of Colombian
    MeSH term(s) Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/pharmacology ; Caco-2 Cells ; Chromatography, High Pressure Liquid ; Humans ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; Mass Spectrometry ; Passiflora/chemistry ; Phytochemicals/chemistry ; Phytochemicals/pharmacology ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; Polyphenols/chemistry ; Polyphenols/isolation & purification ; Polyphenols/pharmacology
    Chemical Substances Anti-Inflammatory Agents ; Phytochemicals ; Plant Extracts ; Polyphenols
    Language English
    Publishing date 2019-12-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules24244614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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