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  1. Book: Effects of persistent and bioactive organic pollutants on human health

    Carpenter, David O.

    2013  

    Author's details ed. by David O. Carpenter
    Keywords Persistenter organischer Schadstoff ; Bioaktive Verbindungen ; Gesundheit ; Toxikologie
    Subject Giftkunde ; Klinische Toxikologie ; Gesundheitsstatus ; Gesundheitszustand ; Biologisch aktive Verbindungen ; Persistent organic pollutants ; POP
    Language English
    Size IX, 598 S. : Ill., graph. Darst.
    Publisher Wiley
    Publishing place Hoboken, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT017799896
    ISBN 978-1-118-15926-2 ; 1-118-15926-8
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Arnold R. Eiser: Preserving brain health in a toxic age: new insights from neuroscience, integrative medicine and public health.

    Carpenter, David O

    Reviews on environmental health

    2022  Volume 37, Issue 4, Page(s) 617

    MeSH term(s) Integrative Medicine ; Public Health ; Neurosciences ; Brain
    Language English
    Publishing date 2022-09-29
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 184450-7
    ISSN 2191-0308 ; 0048-7562 ; 0048-7554
    ISSN (online) 2191-0308
    ISSN 0048-7562 ; 0048-7554
    DOI 10.1515/reveh-2022-0008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Conference proceedings: Environmental challenges in the Pacific basin

    Carpenter, David O.

    [result of the 12th International Conference of the Pacific Basin Consortium for Environment and Health Sciences, Entitled Environment and Health in the 21st Century: Challenges and Solutions and held on October 26 - 29, 2007 at Peking University in Beijing, China]

    (Annals of the New York Academy of Sciences ; 1140)

    2008  

    Institution Pacific Basin Consortium for Environment and Health Sciences
    Event/congress International Conference Entitled Environment and Health in the 21st Century: Challenges and Solutions (2007, Peking)
    Author's details ed. David O. Carpenter
    Series title Annals of the New York Academy of Sciences ; 1140
    Collection
    Language English
    Size XI, 457 S. : Ill., graph. Darst.
    Publisher Blackwell
    Publishing place Boston, Mass
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT015751065
    ISBN 978-1-57331-740-5 ; 1-57331-740-3
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: 40 Years of Cellular and Molecular Neurobiology.

    Carpenter, David O

    Cellular and molecular neurobiology

    2021  Volume 42, Issue 1, Page(s) 1

    MeSH term(s) Brain ; Neurobiology
    Language English
    Publishing date 2021-09-02
    Publishing country United States
    Document type Editorial
    ZDB-ID 283404-2
    ISSN 1573-6830 ; 0272-4340
    ISSN (online) 1573-6830
    ISSN 0272-4340
    DOI 10.1007/s10571-021-01142-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Patterns of Emergency Room Visits for Respiratory Diseases in New York State in Relation to Air Pollution, Poverty and Smoking.

    Madani, Najm Alsadat / Carpenter, David O

    International journal of environmental research and public health

    2023  Volume 20, Issue 4

    Abstract: We have explored differences in rates of emergency room (ER) visits for respiratory diseases in the counties of New York State (NYS) in relation to levels of air pollution, poverty, and smoking. Air pollution information was derived from the National ... ...

    Abstract We have explored differences in rates of emergency room (ER) visits for respiratory diseases in the counties of New York State (NYS) in relation to levels of air pollution, poverty, and smoking. Air pollution information was derived from the National Emissions Inventory, which provides information on road, non-road, point, and non-point sources of 12 different air pollutants. This information is only available at the county level. Four types of respiratory diseases were considered: asthma, chronic obstructive pulmonary disease (COPD), acute lower respiratory diseases, and acute upper respiratory diseases. Asthma ER visits were elevated in counties with greater total air pollution. All forms of respiratory diseases were elevated in counties with a greater rate of poverty, although this may reflect the fact that poor people often use ERs for routine care. There was a very strong association between rates of smoking for COPD and acute lower respiratory diseases. There was an apparent negative association between smoking and asthma ER visits, but this must reflect the fact that smoking was much more common in upstate counties while asthma was more common in the New York City area, where air pollution is high. Air pollution was much greater in urban than in rural areas. Our evidence indicates that air pollution is the greatest risk factor for asthma attacks, whereas smoking is the greatest risk factor for chronic obstructive pulmonary disease (COPD) and lower respiratory disease. Poor people are more vulnerable to all forms of respiratory diseases.
    MeSH term(s) Humans ; Air Pollution ; Asthma/complications ; Pulmonary Disease, Chronic Obstructive/complications ; Air Pollutants ; Respiration Disorders ; Respiratory Tract Diseases/etiology ; Emergency Service, Hospital ; Smoking ; Poverty ; New York City
    Chemical Substances Air Pollutants
    Language English
    Publishing date 2023-02-13
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20043267
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Reply to A Olluri.

    Sasaki, Nozomi / Jones, Laura E / Carpenter, David O

    The American journal of clinical nutrition

    2024  Volume 119, Issue 4, Page(s) 1084–1085

    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Letter
    ZDB-ID 280048-2
    ISSN 1938-3207 ; 0002-9165
    ISSN (online) 1938-3207
    ISSN 0002-9165
    DOI 10.1016/j.ajcnut.2024.01.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Reply to P Ayotte and A Achouba.

    Sasaki, Nozomi / Jones, Laura E / Carpenter, David O

    The American journal of clinical nutrition

    2024  Volume 119, Issue 5, Page(s) 1373–1374

    MeSH term(s) Humans
    Language English
    Publishing date 2024-04-11
    Publishing country United States
    Document type Letter
    ZDB-ID 280048-2
    ISSN 1938-3207 ; 0002-9165
    ISSN (online) 1938-3207
    ISSN 0002-9165
    DOI 10.1016/j.ajcnut.2024.03.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Associations between Metal Exposures and Cognitive Function in American Older Adults.

    Sasaki, Nozomi / Carpenter, David O

    International journal of environmental research and public health

    2022  Volume 19, Issue 4

    Abstract: Cognitive function frequently declines with older age, independently of the development of neurodegenerative diseases, and few interventions are known to counter this decline. Exposure to neurotoxic metals may contribute to this decline in cognitive ... ...

    Abstract Cognitive function frequently declines with older age, independently of the development of neurodegenerative diseases, and few interventions are known to counter this decline. Exposure to neurotoxic metals may contribute to this decline in cognitive function in older adults. Using the National Health and Nutrition Examination Survey (NHANES) data, the performance of 3042 adults aged 60 years and older on three cognitive tests for immediate, delayed, and working memory were examined in relation to blood concentrations of seven metals and metalloids and urinary concentrations of nineteen metals and metabolites. Using linear regression models, associations between cognitive tests and logarithms of metal exposures were adjusted for age, sex, ethnicity, education level, depression, diabetes, alcohol consumption, and cigarette use. Increased selenium was strongly associated with better performance on all three cognitive tests. Cadmium and lead were negatively associated with performance on all three cognitive tests. Some urinary metabolites of arsenic, urinary lead, cadmium, and tungsten were significantly associated with poor performance on some tests. In older adults, higher selenium levels were strongly associated with better cognitive performance.
    MeSH term(s) Arsenic ; Cognition ; Environmental Exposure/analysis ; Metals/toxicity ; Nutrition Surveys ; United States/epidemiology
    Chemical Substances Metals ; Arsenic (N712M78A8G)
    Language English
    Publishing date 2022-02-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19042327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Rodent Brain Tumor Models for Studies Focusing on Boron Neutron Capture Therapy.

    Barth, Rolf F / Carpenter, David E

    Cancer biotherapy & radiopharmaceuticals

    2022  Volume 38, Issue 3, Page(s) 148–151

    Abstract: Rodent brain tumor models have been very useful in advancing the treatment of glioblastomas. This review focuses on the four most widely used rodent brain tumor models: the C6, 9L, and F98 rat gliomas, and the GL261 murine glioma. All of these have been ... ...

    Abstract Rodent brain tumor models have been very useful in advancing the treatment of glioblastomas. This review focuses on the four most widely used rodent brain tumor models: the C6, 9L, and F98 rat gliomas, and the GL261 murine glioma. All of these have been used in studies relating to boron neutron capture therapy. The most important of these studies were those using the 9L gliosarcoma, which led to the clinical use of boronophenylalanine, and the F98 glioma, which has been used for the preclinical evaluation of new boron delivery agents and methods of optimizing their delivery.
    MeSH term(s) Rats ; Mice ; Animals ; Rats, Inbred F344 ; Rodentia ; Boron Neutron Capture Therapy/methods ; Boron Compounds/therapeutic use ; Brain Neoplasms/pathology ; Glioma/radiotherapy ; Glioma/drug therapy
    Chemical Substances Boron Compounds
    Language English
    Publishing date 2022-09-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1315649-4
    ISSN 1557-8852 ; 1084-9785
    ISSN (online) 1557-8852
    ISSN 1084-9785
    DOI 10.1089/cbr.2022.0041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Effects of glyphosate and glyphosate-based herbicides like Roundup™ on the mammalian nervous system: A review.

    Madani, Najm Alsadat / Carpenter, David O

    Environmental research

    2022  Volume 214, Issue Pt 4, Page(s) 113933

    Abstract: Glyphosate is the active ingredient in glyphosate-based herbicides (GBHs), such as Roundup™, the most widely used herbicides in the world. Glyphosate targets an essential enzyme in plants that is not found in animals. However, both glyphosate and GBHs ... ...

    Abstract Glyphosate is the active ingredient in glyphosate-based herbicides (GBHs), such as Roundup™, the most widely used herbicides in the world. Glyphosate targets an essential enzyme in plants that is not found in animals. However, both glyphosate and GBHs are rated as Group 2A, probable human carcinogens, and also have documented effects on reproduction, acting as endocrine disruptive chemicals. We have reviewed reports of the effects of glyphosate and GBHs on mammalian nervous system function. As with several other herbicides, GBHs exposure has been associated with an increased risk of Parkinson's Disease and death of neurons in the substantia nigra. There is also some evidence implicating Roundup™ in elevated risk of autism. Other studies have shown the effects of GBHs on synaptic transmission in animal and cellular studies. The major mechanism of action appears to be oxidative stress, accompanied by mitochondrial dysfunction. In addition, some gut bacteria utilize the enzyme used by plants, and glyphosate and GBHs use has been shown to alter the gut microbiome. There is a large and growing body of evidence that the gut microbiome alters susceptibility to great number of human diseases, including nervous system function. The weight of the evidence indicates that in addition to cancer and reproductive effects, glyphosate and GBHs have significant adverse effects on the brain and behavior and increase the risk of at least some serious neurological diseases.
    MeSH term(s) Animals ; Carcinogens ; Glycine/analogs & derivatives ; Glycine/toxicity ; Herbicides/toxicity ; Humans ; Mammals ; Nervous System ; Glyphosate
    Chemical Substances Carcinogens ; Herbicides ; Glycine (TE7660XO1C)
    Language English
    Publishing date 2022-07-19
    Publishing country Netherlands
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2022.113933
    Database MEDical Literature Analysis and Retrieval System OnLINE

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