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  1. Article ; Online: Predicting postpartum haemorrhage: A systematic review of prognostic models.

    Carr, Bethany L / Jahangirifar, Maryam / Nicholson, Ann E / Li, Wentao / Mol, Ben W / Licqurish, Sharon

    The Australian & New Zealand journal of obstetrics & gynaecology

    2022  Volume 62, Issue 6, Page(s) 813–825

    Abstract: Background: Postpartum haemorrhage (PPH) remains a leading cause of maternal mortality and morbidity worldwide, and the rate is increasing. Using a reliable predictive model could identify those at risk, support management and treatment, and improve ... ...

    Abstract Background: Postpartum haemorrhage (PPH) remains a leading cause of maternal mortality and morbidity worldwide, and the rate is increasing. Using a reliable predictive model could identify those at risk, support management and treatment, and improve maternal outcomes.
    Aims: To systematically identify and appraise existing prognostic models for PPH and ascertain suitability for clinical use.
    Materials and methods: MEDLINE, CINAHL, Embase, and the Cochrane Library were searched using combinations of terms and synonyms, including 'postpartum haemorrhage', 'prognostic model', and 'risk factors'. Observational or experimental studies describing a prognostic model for risk of PPH, published in English, were included. The Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies checklist informed data extraction and the Prediction Model Risk of Bias Assessment Tool guided analysis.
    Results: Sixteen studies met the inclusion criteria after screening 1612 records. All studies were hospital settings from eight different countries. Models were developed for women who experienced vaginal birth (n = 7), caesarean birth (n = 2), any type of birth (n = 2), hypertensive disorders (n = 1) and those with placental abnormalities (n = 4). All studies were at high risk of bias due to use of inappropriate analysis methods or omission of important statistical considerations or suboptimal validation.
    Conclusions: No existing prognostic models for PPH are ready for clinical application. Future research is needed to externally validate existing models and potentially develop a new model that is reliable and applicable to clinical practice.
    MeSH term(s) Female ; Humans ; Pregnancy ; Placenta ; Postpartum Hemorrhage/therapy ; Postpartum Hemorrhage/drug therapy ; Postpartum Period ; Prognosis
    Language English
    Publishing date 2022-08-02
    Publishing country Australia
    Document type Journal Article ; Systematic Review
    ZDB-ID 390815-x
    ISSN 1479-828X ; 0004-8666
    ISSN (online) 1479-828X
    ISSN 0004-8666
    DOI 10.1111/ajo.13599
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Partner delivered relaxation massage to support mild antenatal anxiety; views of participants.

    Hall, Helen / Lauche, Romy / Fogarty, Sarah / Kloester, Joy / Carr, Bethany / Munk, Niki

    Midwifery

    2021  Volume 105, Page(s) 103229

    Abstract: Background: Approximately one-fifth of pregnant women suffer from anxiety and/or depression. These mental health conditions are associated with increased infant and maternal morbidity. Relaxation massage has the potential to improve mental health and ... ...

    Abstract Background: Approximately one-fifth of pregnant women suffer from anxiety and/or depression. These mental health conditions are associated with increased infant and maternal morbidity. Relaxation massage has the potential to improve mental health and may provide a vaulable option for pregnant women. This paper reports on participants' experiences of partner delivered massage as a technique to manage mild antenatal anxiety.
    Methods: We conducted a feasibility study with 44 pregnant women who self-assessed as mildly anxious. The women were randomised into massage therapy (14 women/partner dyads) or to an active control group (13 women). 4-6 weeks after the birth of their baby, massage group participants were invited to be interviewed about their experiences; twelve women and four partners agreed. The qualitative data was analysed using reflective thematic analysis.
    Results: Four themes emerged from the data; Supporting mental health, Connecting, Useful and adaptable and Making it happen. Partner delivered massage was an accessible and practical method to manage mild anxiety for pregnant women in this study. The massage program also provided useful skills for participants to apply in their lives after the birth of their child, which has the potential to continue to support maternal mental health as well as partner connection.
    Conclusion: Partner delivered massage offers low-cost, accessible option for pregnant women to manage their mild anxiety. These findings have particular relevance in the context of the COVID-19 pandemic, where anecdotal reports indicate that antenatal stress is increasing and women may have limited access to healthcare services.
    MeSH term(s) Anxiety/prevention & control ; COVID-19 ; Depression ; Female ; Humans ; Male ; Massage ; Pandemics ; Parturition ; Pregnancy ; SARS-CoV-2
    Language English
    Publishing date 2021-12-20
    Publishing country Scotland
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1036567-9
    ISSN 1532-3099 ; 0266-6138
    ISSN (online) 1532-3099
    ISSN 0266-6138
    DOI 10.1016/j.midw.2021.103229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Recent Advances and New Directions in Measuring Theory of Mind in Autistic Adults.

    Livingston, Lucy Anne / Carr, Bethany / Shah, Punit

    Journal of autism and developmental disorders

    2018  Volume 49, Issue 4, Page(s) 1738–1744

    Abstract: Theory of Mind' (ToM) is the ability to attribute mental states to others to make sense of their behaviour. ToM research has informed understanding of (a)typical social behaviour, including the symptoms of autism spectrum disorder (ASD). This began with ...

    Abstract 'Theory of Mind' (ToM) is the ability to attribute mental states to others to make sense of their behaviour. ToM research has informed understanding of (a)typical social behaviour, including the symptoms of autism spectrum disorder (ASD). This began with research on ToM in autistic children and there has been a noticeable increase in the study of ToM in autistic adults. However, methodological limitations in adult ToM research may be limiting its explanatory power of ASD symptoms and their management, therefore we discuss recent advances in measuring ToM aimed at addressing these issues. We also examine previously overlooked approaches and propose several new directions that have potential to improve the sensitivity, accuracy, and clinical utility of ToM measurement in autistic adulthood.
    MeSH term(s) Adult ; Autism Spectrum Disorder/diagnosis ; Autism Spectrum Disorder/psychology ; Comprehension ; Diagnosis, Computer-Assisted/methods ; Diagnosis, Computer-Assisted/trends ; Female ; Humans ; Male ; Social Behavior ; Theory of Mind/physiology
    Language English
    Publishing date 2018-10-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 391999-7
    ISSN 1573-3432 ; 0162-3257
    ISSN (online) 1573-3432
    ISSN 0162-3257
    DOI 10.1007/s10803-018-3823-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Differences in meconium stained amniotic fluid in an Australian population: A retrospective study.

    Carr, Bethany L / Copnell, Beverley / McIntyre, Meredith

    Women and birth : journal of the Australian College of Midwives

    2018  Volume 32, Issue 2, Page(s) e259–e263

    Abstract: Background: Meconium stained amniotic fluid commonly occurs postdates ( >40 weeks gestation) indicating fetal maturity. Previous literature indicates that different ethnicities mature at different rates.: Aim: To compare the rate of meconium stained ... ...

    Abstract Background: Meconium stained amniotic fluid commonly occurs postdates ( >40 weeks gestation) indicating fetal maturity. Previous literature indicates that different ethnicities mature at different rates.
    Aim: To compare the rate of meconium stained amniotic fluid of Australian-born and non-Australian born women.
    Methods: A retrospective correlation study design was implemented, using data collected in the birth outcomes system at one tertiary hospital. Data was collected from all women who gave birth to a term (>/=37 weeks gestation), singleton, liveborn baby between January 1st to December 31st, 2014. Maternal country of birth was used for comparison. Categorical data was analyzed using Chi-Square test for Independence. Continuous variables were assessed for normality, and differences were compared using an Independent t-test or a Mann-Whitney U test. All tests were two-tailed and p<0.05 was considered statistically significant.
    Results: 3,041 women were included; 1131 Australian-born and 1910 non-Australian born. Meconium stained amniotic fluid occurred more frequently in non-Australian born women compared to Australian-born women (23.5% vs. 19.8 p=0.02). Their babies were significantly smaller (Mean=3265g, Standard Deviation 463.8 vs Mean=3442g, Standard Deviation 499.2, p<0.001), with no difference in gestational length (Mean=39.4, Standard Deviation 1.28 vs Mean=39.5, Standard Deviation 1.18, p=0.06). Increasing gestational age had the strongest association with meconium stained amniotic fluid; >/=42 weeks gestation occurring 3.52 (95% Confidence Interval: 2.00, 6.22, p=<0.001) more than <40 weeks gestation.
    Conclusion: Maternity health services should record ethnicity and region of birth to provide individualised care as women born overseas often have poorer perinatal outcomes when compared to Australian-born women.
    MeSH term(s) Adolescent ; Adult ; Amniotic Fluid/chemistry ; Australia ; Female ; Gestational Age ; Humans ; Infant, Newborn ; Meconium/metabolism ; Middle Aged ; Pregnancy ; Retrospective Studies ; Young Adult
    Language English
    Publishing date 2018-06-25
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2235085-8
    ISSN 1878-1799 ; 1871-5192
    ISSN (online) 1878-1799
    ISSN 1871-5192
    DOI 10.1016/j.wombi.2018.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Maternal mental health and partner-delivered massage: A pilot study.

    Hall, Helen / Munk, Niki / Carr, Bethany / Fogarty, Sarah / Cant, Robyn / Holton, Sara / Weller, Carolina / Lauche, Romy

    Women and birth : journal of the Australian College of Midwives

    2020  Volume 34, Issue 3, Page(s) e237–e247

    Abstract: Background: Anxiety and depression affects many pregnant women. Massage may be beneficial for supporting mental wellbeing during this time. The aim of this study was to assess the feasibility and acceptability of a partner-delivered relaxation massage ... ...

    Abstract Background: Anxiety and depression affects many pregnant women. Massage may be beneficial for supporting mental wellbeing during this time. The aim of this study was to assess the feasibility and acceptability of a partner-delivered relaxation massage program for pregnant women, and its impact on symptoms of antenatal anxiety, stress and depression.
    Methods: A feasibility randomised controlled trial was conducted to compare partner-delivered relaxation massage (intervention) with self-directed stress management (control). Women attended an initial workshop at 28-32 weeks gestation followed by completion of a self-directed massage or stress management program. Qualitative data about the feasibility and acceptability (primary outcomes) were collected via online participant diaries and post-birth interviews. Anxiety, depression and stress symptoms (secondary outcomes) were assessed using the Depression and Anxiety Stress Scale (DASS-21). Birth outcomes were collected at the post- birth interview.
    Results: A total of 14 women/partner dyads in the massage group and 13 women in the self-directed stress management group, attended the initial workshops. When interviewed, participants from both groups reported that the programs were feasible and acceptable. Women's mean scores on all subscales of the DASS-21significantly decreased over time in both the intervention and the control group.
    Conclusion: Pregnant women found the partner-delivered massage program to be feasible and acceptable. Both programs decreased women's symptoms of anxiety, depression and stress with no significant differences identified between the two groups. An adequately powered experimental study with a large representative sample is needed to determine whether partner-delivered relaxation massage reduces pregnant women's symptoms of anxiety, depression and stress.
    MeSH term(s) Adult ; Anxiety/psychology ; Anxiety/therapy ; Depression/psychology ; Depression/therapy ; Family ; Female ; Humans ; Male ; Massage ; Maternal Health ; Mental Health ; Pilot Projects ; Pregnancy ; Pregnancy Complications/psychology ; Pregnant Women/psychology ; Psychotherapy ; Sexual Partners ; Spouses
    Language English
    Publishing date 2020-06-06
    Publishing country Netherlands
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2235085-8
    ISSN 1878-1799 ; 1871-5192
    ISSN (online) 1878-1799
    ISSN 1871-5192
    DOI 10.1016/j.wombi.2020.05.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Normal foetal kidney volume in offspring of women treated for gestational diabetes.

    Hokke, Stacey / de Zoysa, Natasha / Carr, Bethany L / Abruzzo, Veronica / Coombs, Peter R / Allan, Carolyn A / East, Christine / Ingelfinger, Julie R / Puelles, Victor G / Black, Mary J / Ryan, Danica / Armitage, James A / Wallace, Euan M / Bertram, John F / Cullen-McEwen, Luise A

    Endocrinology, diabetes & metabolism

    2019  Volume 2, Issue 4, Page(s) e00091

    Abstract: Aims: The worldwide prevalence of gestational diabetes mellitus (GDM) is increasing. Studies in rodent models indicate that hyperglycaemia during pregnancy alters kidney development, yet few studies have examined if this is so in humans. The objective ... ...

    Abstract Aims: The worldwide prevalence of gestational diabetes mellitus (GDM) is increasing. Studies in rodent models indicate that hyperglycaemia during pregnancy alters kidney development, yet few studies have examined if this is so in humans. The objective of this study was to evaluate the association of treated GDM with foetal kidney size.
    Materials and methods: Participants were recruited from an Australian tertiary hospital, and clinical data were collected from women without GDM and women diagnosed and treated for GDM and their offspring. Participants underwent an obstetric ultrasound at 32-34 weeks gestation for foetal biometry and foetal kidney volume measurement.
    Results: Sixty-four non-GDM and 64 GDM women participated in the study. Thirty percent of GDM women were diagnosed with fasting hyperglycaemia, while 89% had an elevated 2-hour glucose level. Maternal age, weight and body mass index were similar in women with and without GDM. Estimated foetal weight, foetal kidney dimensions, total foetal kidney volume and birth weight were similar in offspring of women with and without GDM.
    Conclusions: We conclude that a period of mild hyperglycaemia prior to diagnosis of GDM and treatment initiation, which coincides with a period of rapid nephron formation and kidney growth, does not alter kidney size at 32-34 weeks gestation.
    Language English
    Publishing date 2019-08-30
    Publishing country England
    Document type Journal Article
    ISSN 2398-9238
    ISSN (online) 2398-9238
    DOI 10.1002/edm2.91
    Database MEDical Literature Analysis and Retrieval System OnLINE

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