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  1. Book ; Online: The EBMT Handbook

    Sureda, Anna / Corbacioglu, Selim / Greco, Raffaella / Kröger, Nicolaus / Carreras, Enric

    Hematopoietic Cell Transplantation and Cellular Therapies

    2024  

    Author's details edited by Anna Sureda, Selim Corbacioglu, Raffaella Greco, Nicolaus Kröger, Enric Carreras
    Keywords Hematology ; Transplantation of organs, tissues, etc ; Internal medicine ; Children/Surgery ; Cancer/Treatment
    Language English
    Size 1 Online-Ressource (XLII, 862 p. 62 illus., 47 illus. in color)
    Edition 8th ed. 2024
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online
    HBZ-ID HT030736098
    ISBN 978-3-031-44080-9 ; 9783031440793 ; 9783031440816 ; 9783031440823 ; 3-031-44080-3 ; 303144079X ; 3031440811 ; 303144082X
    DOI 10.1007/978-3-031-44080-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: The EBMT Handbook

    Carreras, Enric / Dufour, Carlo / Mohty, Mohamad / Kröger, Nicolaus

    Hematopoietic Stem Cell Transplantation and Cellular Therapies

    2019  

    Author's details edited by Enric Carreras, Carlo Dufour, Mohamad Mohty, Nicolaus Kröger
    Keywords Hematology ; Transplantation of organs, tissu ; Blood transfusion ; Surgery ; Surgical oncology
    Subject code 616.15
    Language English
    Size 1 Online-Ressource (XL, 702 p. 56 illus., 38 illus. in color)
    Edition Seventh Edition
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online
    HBZ-ID HT020019839
    ISBN 978-3-030-02278-5 ; 9783030022778 ; 9783030022792 ; 3-030-02278-1 ; 3030022773 ; 303002279X
    DOI 10.1007/978-3-030-02278-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: The EBMT Handbook : Hematopoietic Stem Cell Transplantation and Cellular Therapies

    Carreras, Enric / Dufour, Carlo / Mohty, Mohamad / Kröger, Nicolaus

    2019  

    Keywords Haematology ; General surgery ; Surgical oncology ; Transplant surgery ; Medicine ; Hematology ; Surgical transplantation ; Blood transfusion ; Pediatric surgery
    Size 1 electronic resource (702 pages)
    Publisher Springer Nature
    Publishing place Cham
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021029489
    ISBN 978-3-030-02278-5 ; 3-030-02278-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Vascular endothelial syndromes after HCT: 2020 update.

    Carreras, Enric

    Bone marrow transplantation

    2020  Volume 55, Issue 10, Page(s) 1885–1887

    MeSH term(s) Endothelium, Vascular ; Hematopoietic Stem Cell Transplantation ; Humans ; Syndrome
    Language English
    Publishing date 2020-03-12
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 632854-4
    ISSN 1476-5365 ; 0268-3369 ; 0951-3078
    ISSN (online) 1476-5365
    ISSN 0268-3369 ; 0951-3078
    DOI 10.1038/s41409-020-0852-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2168: Show issues Location:
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  5. Article ; Online: How I manage sinusoidal obstruction syndrome after haematopoietic cell transplantation.

    Carreras, Enric

    British journal of haematology

    2015  Volume 168, Issue 4, Page(s) 481–491

    Abstract: Sinusoidal obstruction syndrome (SOS), also called veno-occlusive disease of the liver, is one of the most relevant complications of endothelial origin that appears early after haematopoietic cell transplantation (HCT). Despite its relatively low ... ...

    Abstract Sinusoidal obstruction syndrome (SOS), also called veno-occlusive disease of the liver, is one of the most relevant complications of endothelial origin that appears early after haematopoietic cell transplantation (HCT). Despite its relatively low incidence and the fact that most cases of SOS resolve spontaneously, the cases that evolve to multi-organ failure (MOF; severe SOS) have a mortality rate higher than 80% and represent one of the major clinical problems after HCT. For this reason, transplantation teams must have a pre-established policy regarding preventive measures in high-risk patients, strict daily control of weight and fluid balance during HCT, homogeneous diagnostic criteria, appropriate complementary studies for a correct differential diagnosis and measures to prevent and manage hepatorenal syndrome; in addition they must also be ready to start early treatment with defibrotide in patients with a possible severe SOS. Due to the lack of definitive evidence to enable the establishment of general recommendations in the management of SOS, this review analyses all of these aspects based on the author's personal experience.
    MeSH term(s) Combined Modality Therapy ; Diagnosis, Differential ; Disease Management ; Drug Therapy, Combination ; Early Diagnosis ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/pathology ; Fluid Therapy ; Hematopoietic Stem Cell Transplantation ; Hepatic Veno-Occlusive Disease/diagnosis ; Hepatic Veno-Occlusive Disease/etiology ; Hepatic Veno-Occlusive Disease/physiopathology ; Hepatic Veno-Occlusive Disease/therapy ; Humans ; Methylprednisolone/therapeutic use ; Multiple Organ Failure/etiology ; Multiple Organ Failure/prevention & control ; Polydeoxyribonucleotides/therapeutic use ; Risk Factors ; Symptom Assessment ; Transplantation Conditioning/adverse effects ; Transplantation Conditioning/methods
    Chemical Substances Polydeoxyribonucleotides ; defibrotide (438HCF2X0M) ; Methylprednisolone (X4W7ZR7023)
    Language English
    Publishing date 2015-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.13215
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Influence of silane interfacial chemistry on the curing process of anionic Polyamide 6 in glass reinforced composites

    Belkhiri, Achraf / Virgilio, Nick / Santanach Carreras, Enric / Esvan, Jérôme / Nassiet, Valérie / Welemane, Hélène / De Almeida, Olivier / Chabert, France

    Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2023 Aug. 09, p.132183-

    2023  , Page(s) 132183–

    Abstract: The manufacturing of composites based on reactive thermoplastic polyamide 6 (PA6), reinforced with glass particles or fibers for structural applications, is quite sensitive to the state of the interface. Surface hydroxyls present at the glass surface can ...

    Abstract The manufacturing of composites based on reactive thermoplastic polyamide 6 (PA6), reinforced with glass particles or fibers for structural applications, is quite sensitive to the state of the interface. Surface hydroxyls present at the glass surface can completely inhibit both the PA6 polymerization and crystallization processes. Care must then be exerted when tuning the interfacial chemistry in this system. This work demonstrates how an adequate choice of silane coupling agent, combined with a precise surface grafting methodology and tight control of hydroxyl groups density on glass particulates, yields kinetics and degrees of polymerization and crystallization comparable to the pure PA6 resin. Various silanes were grafted onto the microparticles and their surfaces were characterized by Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, thermogravimetric analysis, confocal laser scanning microscopy and contact angle measurements. The activator was also grafted onto the glass surface to initiate polymerization directly from the surface. The results showed that all treated glass particles surfaces allowed obtaining a high degree of conversion but with varying polymerization and crystallization kinetics. The results provide fundamental information on the role of the surface chemistry of glass reinforcements on the polymerization and crystallization of PA6, which are essential for the proper control of composite manufacturing.
    Keywords Fourier transform infrared spectroscopy ; X-ray photoelectron spectroscopy ; contact angle ; crystallization ; glass ; microscopy ; particulates ; polyamides ; polymerization ; silane ; thermogravimetry ; thermoplastics ; Anionic ring opening polymerisation of PA6 ; Glass reinforcement ; Silane sizing ; Polymerization kinetics
    Language English
    Dates of publication 2023-0809
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 1500517-3
    ISSN 0927-7757
    ISSN 0927-7757
    DOI 10.1016/j.colsurfa.2023.132183
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Is sickle cell disease-related neurotoxicity a systemic endotheliopathy?

    Palomo, Marta / Diaz-Ricart, Maribel / Carreras, Enric

    Hematology/oncology and stem cell therapy

    2020  Volume 13, Issue 2, Page(s) 111–115

    Abstract: The aim of the present article is to review the role of endothelial damage and dysfunction in the vaso-occlusive episodes associated with sickle cell disease (SCD). This inherited hematological disorder leads to irreversible damage of multiple organs ... ...

    Abstract The aim of the present article is to review the role of endothelial damage and dysfunction in the vaso-occlusive episodes associated with sickle cell disease (SCD). This inherited hematological disorder leads to irreversible damage of multiple organs through a wide variety of mechanisms, such as sickling of red cells, oxidative state due to ischemic-reperfusion episodes, inflammation, hypercoagulation state, and platelet activation, among others. In SCD, the endothelium arises as the key entity where most of these processes, which eventually lead to increased morbidly and mortality, interact. This review begins with the already accepted idea that organ-specific vasculopathy precedes clinical manifestation, and briefly explains one of the main triggers of vaso-occlusive episodes, the complex interplay between blood cells and the dysfunctional endothelium. Endothelial protective strategies emerge as a potential tool for the prevention of organ-specific disease in SCD. Actually, this knowledge is currently used for the development of potential pharmacologic interventions to improve the lives of SCD patients.
    MeSH term(s) Anemia, Sickle Cell/complications ; Humans ; Nervous System Diseases/etiology ; Nervous System Diseases/pathology
    Language English
    Publishing date 2020-03-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2651893-4
    ISSN 1658-3876
    ISSN 1658-3876
    DOI 10.1016/j.hemonc.2019.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6950: Show issues Location:
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  8. Article: Prevención y tratamiento de la enfermedad venooclusiva hepática.

    Carreras, Enric

    Gastroenterologia y hepatologia

    2011  Volume 34, Issue 9, Page(s) 635–640

    Abstract: Hematopoietic stem cell transplantation is currently the main cause of hepatic veno-occlusive disease, which is the early complication of this procedure with the highest short-term morbidity and mortality. Given that mortality from severe hepatic veno- ... ...

    Title translation Prevention and treatment of hepatic veno-occlusive disease.
    Abstract Hematopoietic stem cell transplantation is currently the main cause of hepatic veno-occlusive disease, which is the early complication of this procedure with the highest short-term morbidity and mortality. Given that mortality from severe hepatic veno-occlusive disease can be nearly 100%, the search for measures to prevent of treat this complication is essential. Several risk factors for this complication have been identified and the triggering event that leads to sinusoidal obstruction has been shown to be sinusoidal endothelial cell injury. The present review analyzes measures to avoid or modify the casual risk factors for this complication, as well as the pharmacological agents that can prevent or modify the initial endothelial dysfunction or the resulting sinusoidal occlusion.
    MeSH term(s) Hepatic Veno-Occlusive Disease/prevention & control ; Hepatic Veno-Occlusive Disease/therapy ; Humans
    Language Spanish
    Publishing date 2011-11
    Publishing country Spain
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 632502-6
    ISSN 0210-5705
    ISSN 0210-5705
    DOI 10.1016/j.gastrohep.2011.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2044: Show issues Location:
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  9. Article ; Online: Prevention of veno-occlusive disease/sinusoidal obstruction syndrome: a never-ending story and no easy answer.

    Corbacioglu, Selim / Grupp, Stephan A / Richardson, Paul Gerard / Duarte, Rafael / Pagliuca, Antonio / Ruutu, Tapani / Mahadeo, Kris / Carreras, Enric

    Bone marrow transplantation

    2023  Volume 58, Issue 8, Page(s) 839–841

    MeSH term(s) Humans ; Hepatic Veno-Occlusive Disease/etiology ; Hepatic Veno-Occlusive Disease/prevention & control ; Vascular Diseases ; Hematopoietic Stem Cell Transplantation
    Language English
    Publishing date 2023-05-25
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 632854-4
    ISSN 1476-5365 ; 0268-3369 ; 0951-3078
    ISSN (online) 1476-5365
    ISSN 0268-3369 ; 0951-3078
    DOI 10.1038/s41409-023-02007-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2168: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Endothelial Dysfunction in Hematopoietic Cell Transplantation.

    Palomo, Marta / Diaz-Ricart, Maribel / Carreras, Enric

    Clinical hematology international

    2019  Volume 1, Issue 1, Page(s) 45–51

    Abstract: The goal of this review is to look at the role of endothelial damage and dysfunction in the initiation and development of early complications that appear after hematopoietic cell transplantation (HCT). These early complications share overlapping clinical ...

    Abstract The goal of this review is to look at the role of endothelial damage and dysfunction in the initiation and development of early complications that appear after hematopoietic cell transplantation (HCT). These early complications share overlapping clinical manifestations and the suspicion of underlying endothelial damage. Several studies using different approaches, such as animal and in vitro models, the analysis of soluble biomarkers and clinical findings have provided evidence of this endothelial dysfunction. Historically, the first complication in which the role of endothelial damage was elucidated was the veno-oclusive disease/sinusoidal obstructive syndrome. In the last two decades, increasing evidence of the implication of the endothelium in the pathophysiology of other syndromes such as capillary leak syndrome, transplant-associated microangiopathy, or even graft
    Language English
    Publishing date 2019-03-18
    Publishing country France
    Document type Journal Article ; Review
    ISSN 2590-0048
    ISSN (online) 2590-0048
    DOI 10.2991/chi.d.190317.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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