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Article: Impact of systemic inflammatory markers on the response to Hyperthermic IntraVEsical Chemotherapy (HIVEC) in patients with non-muscle-invasive bladder cancer after bacillus Calmette-Guérin failure.

Chiancone, Francesco / Fabiano, Marco / Carrino, Maurizio / Fedelini, Maurizio / Meccariello, Clemente / Fedelini, Paolo

Arab journal of urology

2021 Volume 19, Issue 1, Page(s) 86–91

Abstract: ... ...

Abstract	Objectives
Language	English
Publishing date	2021-01-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	2631788-6
ISSN	2090-598X
ISSN	2090-598X
DOI	10.1080/2090598X.2021.1874627
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Article ; Online: The role of Protopine associated with Nuciferine in controlling adverse events during hyperthermic intravesical chemotherapy instillations. A nutraceutical approach to control adverse event during intravesical instillations.

Chiancone, Francesco / Carrino, Maurizio / Fedelini, Maurizio / Fabiano, Marco / Persico, Francesco / Meccariello, Clemente / Fedelini, Paolo

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica

2020 Volume 92, Issue 3

Abstract: Objectives: The aim of this study was to analyse the role of two alkaloid, Protopine and Nuciferine, in the prevention and the treatment of the low and mild grade adverse events related to the use of HIVEC® (Hyperthermic IntraVEsical Chemotherapy) ... ...

Abstract	Objectives: The aim of this study was to analyse the role of two alkaloid, Protopine and Nuciferine, in the prevention and the treatment of the low and mild grade adverse events related to the use of HIVEC® (Hyperthermic IntraVEsical Chemotherapy) instillations. Materials and methods: From September 2017 to September 2019, 100 patients were prospectively randomized into two groups: Group A = Protopine and Nuciferine syrup, 10 ml, once a day, for 8 weeks; Group B = placebo (flavoured coloured water), 10 ml, once a day, for 8 weeks. The primary endpoint was the evaluation of the efficacy of the therapy with Protopine and Nuciferine in controlling of the irritative symptoms. The secondary endpoint was the evaluation of the influences of the treatment on the uroflowmetric parameters. Results: The patients of Group A showed a better International Prostatic Symptoms Score (IPSS) score, a better control of urgency symptoms (PPIUS) and tolerate well the pain (VAS score). The treatment doesn't modify Uroflow-Qmax and seems to improve the Uroflow-Voided Volume (ml) without influencing the Uroflow-Post Void Residual volume (PVR). Moreover, the treatment with Protopine and Nuciferine has been proven to be effective in the treatment of overactive bladder (OAB) symptoms. Patients' evaluation of the two different treatments assessed with Patient Global Impression of Improvement questionnaire (PGI-I), demonstrated improvements in the Group A, while the Group B showed a lower satisfaction. Conclusions: Protopine and Nuciferine can be interesting nutraceutical compounds useful to control irritative and pain related symptoms of intravesical chemo/immunotherapy.
MeSH term(s)	Administration, Intravesical ; Aporphines/administration & dosage ; Benzophenanthridines/administration & dosage ; Berberine Alkaloids/administration & dosage ; Dietary Supplements ; Double-Blind Method ; Drug Combinations ; Female ; Humans ; Hyperthermic Intraperitoneal Chemotherapy/adverse effects ; Male ; Middle Aged ; Prospective Studies ; Severity of Illness Index ; Urinary Bladder Neoplasms/drug therapy ; Urinary Bladder, Overactive/drug therapy
Chemical Substances	Aporphines ; Benzophenanthridines ; Berberine Alkaloids ; Drug Combinations ; protopine (UIW569HT35) ; nuciferine (W26UEB90B7)
Language	English
Publishing date	2020-10-01
Publishing country	Italy
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	1153526-x
ISSN	2282-4197 ; 1120-8538 ; 1124-3562
ISSN (online)	2282-4197
ISSN	1120-8538 ; 1124-3562
DOI	10.4081/aiua.2020.3.177
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Article: Outcomes and complications of Hyperthermic IntraVesical Chemotherapy using mitomycin C or epirubicin for patients with non-muscle invasive bladder cancer after bacillus Calmette-Guérin treatment failure.

Chiancone, Francesco / Fabiano, Marco / Fedelini, Maurizio / Meccariello, Clemente / Carrino, Maurizio / Fedelini, Paolo

Central European journal of urology

2020 Volume 73, Issue 3, Page(s) 287–294

Abstract: Introduction: Chemohyperthermia is a feasible option in BCG (bacillus Calmette-Guérin) failure patients who desire bladder preservation. We aimed to assess outcomes and complications of chemohyperthermia using mitomycin C (MMC) or epirubicin (EPI).: ... ...

Abstract	Introduction: Chemohyperthermia is a feasible option in BCG (bacillus Calmette-Guérin) failure patients who desire bladder preservation. We aimed to assess outcomes and complications of chemohyperthermia using mitomycin C (MMC) or epirubicin (EPI). Material and methods: From March 2017 to February 2020, 103 BCG failure or intolerance patients with high-risk NMIBC (non-muscle invasive bladder cancer) underwent a hyperthermic intravesical chemotherapy (HIVEC) regimen. Five patients did not complete at least 5 instillations and were excluded from analysis. MMC was used in 72 out of 98 patients (Group A) while EPI was used in 26 patients (Group B). Response to HIVEC, predictive factors for treatment outcome and the disease-free survival (DFS) were defined as primary endpoints. The complications of chemohyperthermia were assessed as a secondary endpoint. Results: No significant differences were found in recurrence and progression after induction course between Groups A and B. Kaplan-Meier disease-free survival was 22.61 months in Group A and 21.93 in Group B. The log-rank test showed no statistically significant difference between the two curves (p = .627). In the multivariate analysis, patients with tumor size ≥3 cm (p = .029), recurrence rate >1/year (p = .034), concomitant carcinoma in situ (CIS) during transurethral resection of bladder (TURB) (p = .039) and BCG-unresponsive status (p = .048) were associated with a worse response to chemohyperthermia. The use of MMC or EPI did not influence the response to treatment (p = .157). A slightly significant higher rate of overall complications (p = .0488) was observed in Group B. A significantly higher rate of Grade 3 frequency/urgency (p = .0064) contributed to this difference. The use of EPI was the only independent factor associated with severe urinary frequency/urgency (p = .017). No patients experienced Grade 4/5 adverse events. Conclusions: HIVEC can be considered a feasible option in BCG failure/intolerant NMIBC patients, avoiding or postponing radical cystectomy in some particular subclasses of patients.
Language	English
Publishing date	2020-08-06
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2672528-9
ISSN	2080-4873 ; 2080-4806
ISSN (online)	2080-4873
ISSN	2080-4806
DOI	10.5173/ceju.2020.0148
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Article: Preliminary evidence of the impact of social distancing on psychological status and functional outcomes of patients who underwent robot-assisted radical prostatectomy.

Chiancone, Francesco / Fabiano, Marco / Fedelini, Maurizio / Carrino, Maurizio / Meccariello, Clemente / Fedelini, Paolo

Central European journal of urology

2020 Volume 73, Issue 3, Page(s) 265–268

Abstract: Introduction: Social distancing is considered the best strategy to prevent the spread of COVID-19 (COronaVIrus Disease 19). We aimed to analyse the effect of 'social distancing' on the emotional state, post-operative pain and functional outcomes of ... ...

Abstract	Introduction: Social distancing is considered the best strategy to prevent the spread of COVID-19 (COronaVIrus Disease 19). We aimed to analyse the effect of 'social distancing' on the emotional state, post-operative pain and functional outcomes of patients undergoing robot-assisted radical prostatectomy (RARP). Material and methods: We retrospectively reviewed data of male patients who underwent RARP within the study period (from March to April 2019 [Group A = 27 patients] and from March to April 2020 [Group B = 29 patients]). Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) results were collected on the first day of hospitalization. Post-operative pain was assessed using the numerical rating scale (NRS) and visual analogic scale (VAS) after surgery in the post-anesthesia care unit (PACU) and at 24 hours. Functional outcomes were evaluated at the one-month follow-up. Demographic, pathological and peri-operative data were collected for all patients. Results: There were no significant differences in demographics and pathological characteristics amongst the groups. We observed that patients in Group A had a statistically lower value on the PHQ-9 and GAD-7 questionnaires than patients of Group B. Moreover, Group A showed statistically significant better post-operative pain control in PACU and at 24 hours. At one-month follow-up, patients in Group B required more diapers for incontinence than Group A, showing poor early continence. Patients in Group A showed interest in sexual rehabilitation after 1.11 ±.320 months while patients in Group B after 2.59 ±.712 months (p <.001). Moreover, 17 out of 29 patients (58.62%) in Group B were referred to an andrologist, compared to 100% of patients from Group A (p = 0.0006). Conclusions: Social distancing during the COVID-19 pandemic is associated with a poor pre-operative emotional state, as well as influencing post-operative pain, early urinary continence and desire for sexual rehabilitation.
Keywords	covid19
Language	English
Publishing date	2020-08-19
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2672528-9
ISSN	2080-4873 ; 2080-4806
ISSN (online)	2080-4873
ISSN	2080-4806
DOI	10.5173/ceju.2020.0219
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Article ; Online: The Use of a Combination of Vaccinium Macracarpon, Lycium barbarum L. and Probiotics (Bifiprost®) for the Prevention of Chronic Bacterial Prostatitis: A Double-Blind Randomized Study.

Chiancone, Francesco / Carrino, Maurizio / Meccariello, Clemente / Pucci, Luigi / Fedelini, Maurizio / Fedelini, Paolo

Urologia internationalis

2019 Volume 103, Issue 4, Page(s) 423–426

Abstract: Introduction: To evaluate the efficacy of Bifiprost® + Serenoa Repens 320 mg versus Serenoa Repens 320 mg alone for the prevention of chronic bacterial prostatitis (CBP) due to enterobacteriaceae.: Methods: Between September 2016 and September 2018, ... ...

Abstract	Introduction: To evaluate the efficacy of Bifiprost® + Serenoa Repens 320 mg versus Serenoa Repens 320 mg alone for the prevention of chronic bacterial prostatitis (CBP) due to enterobacteriaceae. Methods: Between September 2016 and September 2018, 120 patients with CBP at the National Institutes of Health (NIH type II) with recurrent infections due to enterobacteriaceae (Escherichia Coli and Enterococcus faecalis) were enrolled and randomized into 2 groups each to receive Bifiprost® + Serenoa Repens 320 mg (Group A) or Serenoa Repens 320 mg alone (Group B) daily for 24 weeks (after receiving a proper antibiotic treatment with subsequent culture negativization). The primary endpoint was the reduction in the episodes of prostatitis. The secondary endpoint evaluated was the score of the NIH-Chronic Prostatitis Symptom Index (NIH-CPSI). Evaluation was performed at baseline and at 12, 24, and 36 weeks. Results: The patients of the Group A experienced a significantly larger reduction in the prostatitis episodes than the Group B at 24 and 36 weeks, but they did not experience a significantly larger reduction at 12 weeks. After 12 weeks of treatment, the mean NIH-CPSI score was reduced in both groups compared with baselines, but no significant differences were seen between the Group A and Group B. On the contrary, we observed a significant difference in the mean NIH-CPSI score between the 2 groups at 24 and 36 weeks. Conclusion: The association of Bifiprost® and Serenoa Repens 320 mg improves the prevention of the episodes of CBP due to enterobacteriaceae and ameliorates prostatitis-related symptoms after 6 months of therapy. The long-term impact on the entero-urinary route was also seen 3 months after the end of the treatment.
MeSH term(s)	Adult ; Bacterial Infections/prevention & control ; Chronic Disease ; Combined Modality Therapy ; Double-Blind Method ; Humans ; Lycium ; Male ; Middle Aged ; Phytotherapy ; Plant Extracts/therapeutic use ; Probiotics ; Prostatitis/microbiology ; Prostatitis/prevention & control ; Vaccinium macrocarpon
Chemical Substances	Plant Extracts ; saw palmetto extract (J7WWH9M8QS)
Language	English
Publishing date	2019-09-17
Publishing country	Switzerland
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	204045-1
ISSN	1423-0399 ; 0042-1138
ISSN (online)	1423-0399
ISSN	0042-1138
DOI	10.1159/000502765
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Article: MRI-Cavernosography: A New Diagnostic Tool for Erectile Dysfunction Due to Venous Leakage: A Diagnostic Chance.

Di Serafino, Marco / Pucci, Luigi / Iacobellis, Francesca / Fasbender Jacobitti, Marco / Ronza, Roberto / Sabatino, Vittorio / De Luca, Luigi / Iossa, Vincenzo / Langella, Nunzio Alberto / Persico, Francesco / Grimaldi, Dario / Schillirò, Maria Laura / Lessoni, Luca / Notorio, Maurizio / Carrino, Maurizio / Romano, Luigia

Diagnostics (Basel, Switzerland)

2023 Volume 13, Issue 13

Abstract: Erectile dysfunction caused by venous leakage is a vascular disease in which blood fails to accumulate in the corpora cavernosa due to the abrupt drainage of blood from the penis secondary to an abnormal venous network that affects 1 to 2% of men under ... ...

Abstract	Erectile dysfunction caused by venous leakage is a vascular disease in which blood fails to accumulate in the corpora cavernosa due to the abrupt drainage of blood from the penis secondary to an abnormal venous network that affects 1 to 2% of men under 25 years old and about 10 to 20% over 60 years old, who do not raise a sufficient erection for penetrative sex. The study of the venous leak and its characterization in young patients with erectile dysfunction represent a diagnostic challenge, and imaging remains the best way to diagnose this condition. In the article, it is described the methods of execution and the diagnostic role of the cavernous MRI in the study of vasogenic erectile dysfunction from the venous leak, proposing it as a good alternative to the cavernous CT, considering the satisfactory results in terms of diagnostic interpretation, the absence of ionizing radiation, the higher soft tissue resolution of the imaging method and the lower administration of contrast agent.
Language	English
Publishing date	2023-06-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics13132178
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Article: Distal corporoplasty for distal cylinders extrusion after penile prosthesis implantation.

Carrino, Maurizio / Chiancone, Francesco / Battaglia, Gaetano / Pucci, Luigi / Fedelini, Paolo

Urologia

2017 Volume 84, Issue 1, Page(s) 38–39

Abstract: Introduction: Distal extrusion of cylinders is a potential complication of the penile prosthesis implantation. Several methods have been proposed for repairing a distal penile erosion. We present our preliminary experience in "Distal corporoplasty" ... ...

Abstract	Introduction: Distal extrusion of cylinders is a potential complication of the penile prosthesis implantation. Several methods have been proposed for repairing a distal penile erosion. We present our preliminary experience in "Distal corporoplasty" technique. Methods: We enrolled 18 consecutive patients whose underwent a distal corporoplasty with simultaneous reimplantation of an "AMS 700 inflatable penile prosthesis (LGX)" from January 2013 to November 2015 at our hospital. All procedures were performed by a single surgical team. Intraoperative and postoperative complications have been classified and reported according to Satava6 and Clavien-Dindo (CD) system.7 Mean values with standard deviations (±SD) were computed and reported for all items. Results: Mean age of the patients was 53.61 (±11.90) years. Mean body max index (BMI) was 24.22 (±2.51). Mean operative time was 85.2 (±13.1) minutes. Blood losses were minimal. No intraoperative complications are reported according to Satava classification. Four out of 18 patients (22.22%) experienced postoperative complications according to CD system. All patients had sexual intercourse for the first time postsurgery after a mean of 59.11 ± 2.08 days. Mean follow-up was 22.11 (±9.95). Discussions: Distal extrusion of cylinders is a potential complication of the penile prosthesis implantation. Distal corporoplasty was first described by Mulcahy. He reported a series of 14 patients with a follow-up of about 2 years with optimal functional outcomes. Moreover, distal corporoplasty resulted in shorter operative time, better function, less pain, and fewer recurrences than Gortex windsock repair.10 In our experience, distal corporoplasty is a simple and safe procedure in the treatment of distal cylinders extrusion when the prosthetic material is not exposed to the exterior.
MeSH term(s)	Foreign-Body Migration/surgery ; Humans ; Male ; Middle Aged ; Penile Implantation ; Penile Prosthesis/adverse effects ; Penis/surgery ; Postoperative Complications/surgery ; Prosthesis Failure ; Urologic Surgical Procedures, Male/methods
Language	English
Publishing date	2017-02-03
Publishing country	Italy
Document type	Journal Article
ZDB-ID	204043-8
ISSN	1724-6075 ; 0391-5603 ; 0376-0057
ISSN (online)	1724-6075
ISSN	0391-5603 ; 0376-0057
DOI	10.5301/uro.5000191
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Article ; Online: Efficacy and safety profile of GreenLight laser photoselective vaporization of the prostate in ≥ 75 years old patients: results from the Italian GreenLight Laser Study Group.

Campobasso, Davide / Morselli, Simone / Greco, Francesco / De Nunzio, Cosimo / Destefanis, Paolo / Fasolis, Giuseppe / Varvello, Francesco / Voce, Salvatore / Reale, Giulio / Cai, Tommaso / Oriti, Rino / Tuccio, Agostino / Ruggera, Lorenzo / Laganà, Antonino / Dadone, Claudio / Gontero, Paolo / De Rienzo, Gaetano / Pucci, Luigi / Carrino, Maurizio /

Montefiore, Franco / Rabito, Salvatore / Miano, Roberto / Schips, Luigi / Frattini, Antonio / Micali, Salvatore / Ferrari, Giovanni / Cindolo, Luca

Aging clinical and experimental research

2023 Volume 35, Issue 4, Page(s) 877–885

Abstract: Background: Benign Prostatic Obstruction (BPO) is the most common non-malignant urological condition among men and its incidence rise with age. Among prostate treatments, GreenLight laser seems to reduce bleeding and would be safer in the aging ... ...

Abstract	Background: Benign Prostatic Obstruction (BPO) is the most common non-malignant urological condition among men and its incidence rise with age. Among prostate treatments, GreenLight laser seems to reduce bleeding and would be safer in the aging population. Aims: We aimed to compare the functional outcomes and safety profile of < 75 years old (Group A) and ≥ 75 years old (Group B) patients. Methods: In a multicenter setting, we retrospectively analyzed all the patients treated with GreenLight Laser vaporization of the prostate (PVP). Results: 1077 patients were eligible for this study. 757 belonged to Group A (median age 66 years) and 320 to Group B (median age 78 years). No differences were present between the two groups in terms of prostate volume, operative time, hospital stay, PSA decrease over time after surgery, complications and re-intervention rate with a median follow-up period of 18 months (IQR 12-26). Nevertheless, focusing on complications, GreenLight laser PVP demonstrated an excellent safety profile in terms of hospital stay, re-intervention and complications, with an overall 29.6% complication rate in older patients and only two cases of Clavien III. Functional outcomes were similar at 12 month and became in favor of Group A over time. These data are satisfactory with a Qmax improvement of 111.7% and an IPSS reduction of 69.5% in older patients. Discussion and conclusions: GreenLight laser photoselective vaporization of the prostate is a safe and efficient procedure for all patients, despite their age, with comparable outcomes and an equal safety profile.
MeSH term(s)	Male ; Humans ; Aged ; Prostate/surgery ; Prostate/pathology ; Prostatic Hyperplasia/surgery ; Prostatic Hyperplasia/complications ; Prostatic Hyperplasia/pathology ; Retrospective Studies ; Volatilization ; Lasers ; Laser Therapy/adverse effects ; Laser Therapy/methods ; Treatment Outcome
Language	English
Publishing date	2023-02-10
Publishing country	Germany
Document type	Multicenter Study ; Journal Article
ZDB-ID	2104785-6
ISSN	1720-8319 ; 1594-0667
ISSN (online)	1720-8319
ISSN	1594-0667
DOI	10.1007/s40520-023-02351-9
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Article: The Use of a Combination of Vaccinium Macracarpon, Lycium barbarum L. and Probiotics (Bifiprost®) for the Prevention of Chronic Bacterial Prostatitis: A Double-Blind Randomized Study

Chiancone, Francesco / Carrino, Maurizio / Meccariello, Clemente / Pucci, Luigi / Fedelini, Maurizio / Fedelini, Paolo

Urologia Internationalis

2019 Volume 103, Issue 4, Page(s) 423–426

Abstract: Introduction: To evaluate the efficacy of Bifiprost® + Serenoa Repens 320 mg versus Serenoa Repens 320 mg alone for the prevention of chronic bacterial prostatitis (CBP) due to enterobacteriaceae. Methods: Between September 2016 and September 2018, 120 ... ...

Institution	Department of Urology, AORN A.Cardarelli, Naples, Italy Department of Andrology, AORN A.Cardarelli, Naples, Italy
Abstract	Introduction: To evaluate the efficacy of Bifiprost® + Serenoa Repens 320 mg versus Serenoa Repens 320 mg alone for the prevention of chronic bacterial prostatitis (CBP) due to enterobacteriaceae. Methods: Between September 2016 and September 2018, 120 patients with CBP at the National Institutes of Health (NIH type II) with recurrent infections due to enterobacteriaceae (Escherichia Coli and Enterococcus faecalis) were enrolled and randomized into 2 groups each to receive Bifiprost® + Serenoa Repens 320 mg (Group A) or Serenoa Repens 320 mg alone (Group B) daily for 24 weeks (after receiving a proper antibiotic treatment with subsequent culture negativization). The primary endpoint was the reduction in the episodes of prostatitis. The secondary endpoint evaluated was the score of the NIH-Chronic Prostatitis Symptom Index (NIH-CPSI). Evaluation was performed at baseline and at 12, 24, and 36 weeks. Results: The patients of the Group A experienced a significantly larger reduction in the prostatitis episodes than the Group B at 24 and 36 weeks, but they did not experience a significantly larger reduction at 12 weeks. After 12 weeks of treatment, the mean NIH-CPSI score was reduced in both groups compared with baselines, but no significant differences were seen between the Group A and Group B. On the contrary, we observed a significant difference in the mean NIH-CPSI score between the 2 groups at 24 and 36 weeks. Conclusion: The association of Bifiprost® and Serenoa Repens 320 mg improves the prevention of the episodes of CBP due to enterobacteriaceae and ameliorates prostatitis-related symptoms after 6 months of therapy. The long-term impact on the entero-urinary route was also seen 3 months after the end of the treatment.
Keywords	Prostate ; Prostatitis ; Symptoms ; Inflammation ; Entero-urinary route ; Probiotic
Language	English
Publishing date	2019-09-17
Publisher	S. Karger AG
Publishing place	Basel, Switzerland
Document type	Article
Note	Original Paper
ZDB-ID	204045-1
ISSN	1423-0399 ; 0042-1138
ISSN (online)	1423-0399
ISSN	0042-1138
DOI	10.1159/000502765
Database	Karger publisher's database

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Article: Rare complication after a transrectal ultrasound guided prostate biopsy: a giant retroperitoneal hematoma.

Chiancone, Francesco / Mirone, Vincenzo / Fedelini, Maurizio / Meccariello, Clemente / Pucci, Luigi / Carrino, Maurizio / Fedelini, Paolo

Urologia

2016 Volume 83, Issue 2, Page(s) 103–105

Abstract: Common complications related to transrectal ultrasound (TRUS) guided prostatic needle biopsy are hematuria, hematospermia, and hematochezia. To the best of our knowledge, we report the second case of a very large hematoma extending from the pelvis into ... ...

Abstract	Common complications related to transrectal ultrasound (TRUS) guided prostatic needle biopsy are hematuria, hematospermia, and hematochezia. To the best of our knowledge, we report the second case of a very large hematoma extending from the pelvis into the retroperitoneal space in literature.A 66-year-old man with a serum prostate-specific antigen (PSA) of 5.4 ng/ml was admitted to our department for a TRUS-guided prostatic needle biopsy. Laboratory values on the day before biopsy, including coagulation studies, were all normal. The patients did not take any anticoagulant drugs. No immediate complications were encountered. Nevertheless, 7 hours after the biopsy, the patient reached our emergency department with severe diffuse abdominal pain, hypotension, tachycardia, and confusional state. He underwent an ultrasonography and then a computed tomography (CT) scan that showed "a blood collection in the pelvis that extending to the lower pole of left kidney associated with a focus of active contrast extravasation, indicating active ongoing prostate bleeding." Consequently, he underwent a diagnostic angiography that showed no more contrast extravasation, without the need of embolization. Management of hematoma has been conservative and hematoma was completely reabsorbed 4 months later.
MeSH term(s)	Aged ; Hematoma/etiology ; Hematoma/pathology ; Humans ; Image-Guided Biopsy/adverse effects ; Image-Guided Biopsy/methods ; Male ; Prostate/pathology ; Rectum ; Retroperitoneal Space ; Ultrasonography, Interventional
Language	English
Publishing date	2016-05-24
Publishing country	Italy
Document type	Case Reports ; Journal Article
ZDB-ID	204043-8
ISSN	1724-6075 ; 0391-5603 ; 0376-0057
ISSN (online)	1724-6075
ISSN	0391-5603 ; 0376-0057
DOI	10.5301/uro.5000161
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