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  1. Article ; Online: Structure Revision of Formyl Phloroglucinol Meroterpenoids: A Unified Approach Using NMR Fingerprinting and DFT NMR and ECD Analyses.

    Holland, Darren C / Carroll, Anthony R

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 3

    Abstract: NMR fingerprints are valuable tools for analyzing complex natural product mixtures and identifying incorrectly assigned structures in the literature. Our diagnostic NMR fingerprints for formyl phloroglucinol meroterpenoids revealed discrepancies in the ... ...

    Abstract NMR fingerprints are valuable tools for analyzing complex natural product mixtures and identifying incorrectly assigned structures in the literature. Our diagnostic NMR fingerprints for formyl phloroglucinol meroterpenoids revealed discrepancies in the structures reported for eucalyprobusal C (
    Language English
    Publishing date 2024-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29030594
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  2. Article ; Online: Marine indole alkaloid diversity and bioactivity. What do we know and what are we missing?

    Holland, Darren C / Carroll, Anthony R

    Natural product reports

    2023  Volume 40, Issue 10, Page(s) 1595–1607

    Abstract: Covering: marine indole alkaloids ( ...

    Abstract Covering: marine indole alkaloids (
    MeSH term(s) Indole Alkaloids/pharmacology ; Indole Alkaloids/chemistry ; Antineoplastic Agents ; Anti-Infective Agents ; Biological Products/pharmacology ; Biological Products/chemistry ; Antifungal Agents
    Chemical Substances Indole Alkaloids ; Antineoplastic Agents ; Anti-Infective Agents ; Biological Products ; Antifungal Agents
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Meta-Analysis ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/d2np00085g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Letter to the editor on "Antimicrobial compounds isolated from

    Jenkins, Ian D / Carroll, Anthony R

    Natural product research

    2023  Volume 38, Issue 10, Page(s) 1812

    Abstract: A bisphosphonate recently isolated from Tropaeolum tuberosum is almost certainly a contaminant and not a genuine natural product. ...

    Abstract A bisphosphonate recently isolated from Tropaeolum tuberosum is almost certainly a contaminant and not a genuine natural product.
    MeSH term(s) Tropaeolum ; Anti-Infective Agents
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2023-06-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2023.2219817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Marine natural products.

    Carroll, Anthony R / Copp, Brent R / Grkovic, Tanja / Keyzers, Robert A / Prinsep, Michèle R

    Natural product reports

    2024  Volume 41, Issue 2, Page(s) 162–207

    Abstract: Covering: January to the end of December 2022This review covers the literature published in 2022 for marine natural products (MNPs), with 645 citations (633 for the period January to December 2022) referring to compounds isolated from marine ... ...

    Abstract Covering: January to the end of December 2022This review covers the literature published in 2022 for marine natural products (MNPs), with 645 citations (633 for the period January to December 2022) referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, the submerged parts of mangroves and other intertidal plants. The emphasis is on new compounds (1417 in 384 papers for 2022), together with the relevant biological activities, source organisms and country of origin. Pertinent reviews, biosynthetic studies, first syntheses, and syntheses that led to the revision of structures or stereochemistries, have been included. An analysis of NP structure class diversity in relation to biota source and biome is discussed.
    MeSH term(s) Animals ; Biological Products/chemistry ; Marine Biology ; Molecular Structure ; Cnidaria/chemistry ; Echinodermata/chemistry ; Aquatic Organisms
    Chemical Substances Biological Products
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/d3np00061c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: How different are marine microbial natural products compared to their terrestrial counterparts?

    Voser, Tanja M / Campbell, Max D / Carroll, Anthony R

    Natural product reports

    2022  Volume 39, Issue 1, Page(s) 7–19

    Abstract: Covering: 1877 to 2020A key challenge in natural products research is the selection of biodiversity to yield novel chemistry. Recently, marine microorganisms have become a preferred source. But how novel are marine microorganism natural products compared ...

    Abstract Covering: 1877 to 2020A key challenge in natural products research is the selection of biodiversity to yield novel chemistry. Recently, marine microorganisms have become a preferred source. But how novel are marine microorganism natural products compared to those reported from terrestrial microbes? Cluster analysis of chemical fingerprints and molecular scaffold analysis of 55 817 compounds reported from marine and terrestrial microorganisms, and marine macro-organisms showed that 76.7% of the compounds isolated from marine microorganisms are closely related to compounds isolated from terrestrial microorganisms. Only 14.3% of marine microorganism natural products are unique when marine macro-organism natural products are also considered. Studies targeting marine specific and understudied microbial phyla result in a higher likelihood of finding marine specific compounds, whereas the depth and geographic location of microorganism collection have little influence. We recommend marine targeted strain isolation, incorporating early use of genomic sequencing to guide strain selection, innovation in culture media and cultivation techniques and the application of cheminformatics tools to focus on unique natural product diversity, rather than the dereplication of known compounds.
    MeSH term(s) Aquatic Organisms/chemistry ; Aquatic Organisms/metabolism ; Biodiversity ; Biological Products/chemistry ; Molecular Structure
    Chemical Substances Biological Products
    Language English
    Publishing date 2022-01-26
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/d1np00051a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Echiumin E, an Aryl Dihydronaphthalene Lignan from the Australian Invasive Plant Paterson's Curse (

    Jin, Ju / Holland, Darren C / Carroll, Anthony R / Zunk, Matthew

    Journal of natural products

    2022  Volume 85, Issue 10, Page(s) 2474–2479

    Abstract: A new aryl dihydronaphthalene lignan, echiumin E ( ...

    Abstract A new aryl dihydronaphthalene lignan, echiumin E (
    MeSH term(s) Male ; Humans ; Echium/chemistry ; Echium/metabolism ; HeLa Cells ; Australia ; Neuroblastoma ; Lignans/pharmacology ; Lignans/metabolism ; Plants
    Chemical Substances Lignans
    Language English
    Publishing date 2022-09-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/acs.jnatprod.2c00151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1144: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Camaldulensals A-C, the First Meroterpenoids Possessing Two Spatially Separated Formyl Phloroglucinols Conjugated to a Terpene Core from the Leaves of

    Daus, Mareena / Hayton, Joshua B / Holland, Darren C / Voravuthikunchai, Supayang P / Carroll, Anthony R / Chakthong, Suda

    Journal of natural products

    2023  Volume 86, Issue 8, Page(s) 1994–2005

    Abstract: Three new bis-formyl phloroglucinol-meroterpenoids ( ...

    Abstract Three new bis-formyl phloroglucinol-meroterpenoids (
    MeSH term(s) Terpenes/chemistry ; Eucalyptus/chemistry ; Phloroglucinol/pharmacology ; Phloroglucinol/chemistry ; Methicillin-Resistant Staphylococcus aureus ; Plant Leaves/chemistry ; Molecular Structure
    Chemical Substances Terpenes ; Phloroglucinol (DHD7FFG6YS)
    Language English
    Publishing date 2023-08-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/acs.jnatprod.3c00443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1144: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Marine natural products.

    Carroll, Anthony R / Copp, Brent R / Davis, Rohan A / Keyzers, Robert A / Prinsep, Michèle R

    Natural product reports

    2023  Volume 40, Issue 2, Page(s) 275–325

    Abstract: Covering: January to December 2021This review covers the literature published in 2021 for marine natural products (MNPs), with 736 citations (724 for the period January to December 2021) referring to compounds isolated from marine microorganisms and ... ...

    Abstract Covering: January to December 2021This review covers the literature published in 2021 for marine natural products (MNPs), with 736 citations (724 for the period January to December 2021) referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms. The emphasis is on new compounds (1425 in 416 papers for 2021), together with the relevant biological activities, source organisms and country of origin. Pertinent reviews, biosynthetic studies, first syntheses, and syntheses that led to the revision of structures or stereochemistries, have been included. An analysis of the number of authors, their affiliations, domestic and international collection locations, focus of MNP studies, citation metrics and journal choices is discussed.
    MeSH term(s) Animals ; Biological Products/chemistry ; Marine Biology ; Molecular Structure ; Cnidaria/chemistry ; Echinodermata/chemistry ; Aquatic Organisms
    Chemical Substances Biological Products
    Language English
    Publishing date 2023-02-22
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/d2np00083k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: How different are marine microbial natural products compared to their terrestrial counterparts?

    Voser, Tanja M. / Campbell, Max D. / Carroll, Anthony R.

    Natural product reports. 2022 Jan. 26, v. 39, no. 1

    2022  

    Abstract: A key challenge in natural products research is the selection of biodiversity to yield novel chemistry. Recently, marine microorganisms have become a preferred source. But how novel are marine microorganism natural products compared to those reported ... ...

    Abstract A key challenge in natural products research is the selection of biodiversity to yield novel chemistry. Recently, marine microorganisms have become a preferred source. But how novel are marine microorganism natural products compared to those reported from terrestrial microbes? Cluster analysis of chemical fingerprints and molecular scaffold analysis of 55 817 compounds reported from marine and terrestrial microorganisms, and marine macro-organisms showed that 76.7% of the compounds isolated from marine microorganisms are closely related to compounds isolated from terrestrial microorganisms. Only 14.3% of marine microorganism natural products are unique when marine macro-organism natural products are also considered. Studies targeting marine specific and understudied microbial phyla result in a higher likelihood of finding marine specific compounds, whereas the depth and geographic location of microorganism collection have little influence. We recommend marine targeted strain isolation, incorporating early use of genomic sequencing to guide strain selection, innovation in culture media and cultivation techniques and the application of cheminformatics tools to focus on unique natural product diversity, rather than the dereplication of known compounds.
    Keywords biodiversity ; chemoinformatics ; cluster analysis ; genomics
    Language English
    Dates of publication 2022-0126
    Size p. 7-19.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/d1np00051a
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Structure Revisions of the Sponge-Derived Dibrominated Bis-indole Alkaloids, Echinosulfone A and the Echinosulfonic Acids A to D.

    Holland, Darren C / Kiefel, Milton J / Carroll, Anthony R

    The Journal of organic chemistry

    2020  Volume 85, Issue 5, Page(s) 3490–3496

    Abstract: The structures of the sponge-derived dibrominated bis-indole alkaloids, namely, echinosulfone A ( ...

    Abstract The structures of the sponge-derived dibrominated bis-indole alkaloids, namely, echinosulfone A (
    MeSH term(s) Alkaloids ; Indole Alkaloids ; Magnetic Resonance Spectroscopy ; Molecular Structure
    Chemical Substances Alkaloids ; Indole Alkaloids
    Language English
    Publishing date 2020-02-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.9b03221
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4473: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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